clofibrate and probenecid

clofibrate has been researched along with probenecid in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19909 (52.94)18.7374
1990's1 (5.88)18.2507
2000's1 (5.88)29.6817
2010's6 (35.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Fent, K; Popovic, M; Smital, T; Zaja, R1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Ryan, JR1
Paoletti, R; Sirtori, C; Spano, PF1
Nies, AS1
Fabre, J; Herrera, A; Perrin, L; Petitpierre, B; Rudhardt, M1
Baer, JE; Bohn, DL; Fanelli, GM; Reilly, SS1
Meffin, PJ; Veenendaal, JR; Zilm, DM1
Meffin, PJ; Veenendaal, JR1
Gut, JP1
Brooks, PM; Meffin, PJ; Veenendaal, JR1
Benet, LZ; Lin, ET; Mizuma, T1

Reviews

4 review(s) available for clofibrate and probenecid

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Clinical relevance of drugs affecting tryptophan transport.
    Annual review of pharmacology, 1975, Volume: 15

    Topics: Anti-Inflammatory Agents; Biological Transport; Clofibrate; Contraceptives, Oral; Female; Humans; Probenecid; Time Factors; Tryptophan

1975
Drug interactions.
    The Medical clinics of North America, 1974, Volume: 58, Issue:5

    Topics: Anabolic Agents; Antidepressive Agents; Biological Transport, Active; Cholestyramine Resin; Clofibrate; Drug Interactions; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Kaolin; Kidney; Pharmaceutical Preparations; Phenylbutazone; Probenecid; Protein Binding; Thyroxine; Warfarin

1974

Trials

1 trial(s) available for clofibrate and probenecid

ArticleYear
The metabolic spectrum of halofenate.
    International journal of clinical pharmacology and biopharmacy, 1975, Volume: 12, Issue:1-2

    Topics: Blood Glucose; Cholesterol; Clinical Trials as Topic; Clofibrate; Creatine Kinase; Glycolates; Halofenate; Humans; Hyperlipidemias; Probenecid; Protein Binding; Thyroid Function Tests; Thyroxine; Tolbutamide; Triglycerides; Uric Acid

1975

Other Studies

12 other study(ies) available for clofibrate and probenecid

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Molecular characterization of zebrafish Oatp1d1 (Slco1d1), a novel organic anion-transporting polypeptide.
    The Journal of biological chemistry, 2013, Nov-22, Volume: 288, Issue:47

    Topics: Animals; Evolution, Molecular; Glycosylation; Gonadal Steroid Hormones; HEK293 Cells; Humans; Ion Transport; Organic Anion Transporters; Protein Multimerization; Zebrafish; Zebrafish Proteins

2013
Behaviour of chlorpropamide in renal insufficiency and under the effect of associated drug therapy.
    International journal of clinical pharmacology, therapy and toxicology, 1972, Volume: 6, Issue:2

    Topics: Acenocoumarol; Allopurinol; Chloramphenicol; Chlorpropamide; Clofibrate; Glomerular Filtration Rate; Glomerulonephritis; Half-Life; Humans; Kidney; Kidney Diseases; Probenecid; Pyelonephritis

1972
Renal excretion and uricosuric properties of halofenate, a hypolipidemic-uricosuric agent, in the chimpanzee.
    The Journal of pharmacology and experimental therapeutics, 1972, Volume: 180, Issue:2

    Topics: Acetamides; Aminohippuric Acids; Animals; Carbon Isotopes; Carboxylic Acids; Clofibrate; Diuresis; Fluorine; Glycolates; Hydrogen-Ion Concentration; Hypolipidemic Agents; Kidney; Kidney Function Tests; Kidney Tubules; Kinetics; Male; Pan troglodytes; Probenecid; Pyrazines; Salicylates; Uricosuric Agents

1972
A renal mechanism for the clofibric acid-probenecid interaction.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:3

    Topics: Animals; Clofibrate; Clofibric Acid; Drug Interactions; Glucuronates; Hydrolysis; Kidney; Probenecid; Rabbits; Time Factors

1983
The simultaneous analysis of clofibric acid and probenecid and the direct analysis of clofibric acid glucuronide by high-performance liquid chromatography.
    Journal of chromatography, 1981, Apr-10, Volume: 223, Issue:1

    Topics: Chromatography, High Pressure Liquid; Clofibrate; Clofibric Acid; Glucuronates; Glucuronidase; Humans; Probenecid

1981
[Changes in indications for drugs].
    La Revue du praticien, 1980, Feb-01, Volume: 30, Issue:7

    Topics: Amantadine; Clofibrate; Colchicine; Drug Therapy; Female; Gout; Humans; Levamisole; Metronidazole; Middle Aged; Probenecid; Sulfinpyrazone

1980
Probenecid-clofibrate interaction.
    Clinical pharmacology and therapeutics, 1981, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Clofibrate; Drug Interactions; Female; Glucuronates; Humans; Indomethacin; Metabolic Clearance Rate; Probenecid; Protein Binding

1981
Preparative chromatography of furosemide 1-O-acyl-glucuronide from urine using micronized amberiite XAD-2 and its application to other 1-O-acyl-glucuronides.
    Preparative biochemistry & biotechnology, 1998, Volume: 28, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzimidazoles; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Clofibrate; Flufenamic Acid; Furosemide; Glucuronates; Glucuronidase; Indomethacin; Mass Spectrometry; Molecular Structure; Probenecid; Tolmetin

1998