clofibrate and nad

clofibrate has been researched along with nad in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199015 (53.57)18.7374
1990's9 (32.14)18.2507
2000's3 (10.71)29.6817
2010's1 (3.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Hashimoto, T; Imura, M; Miyazawa, S; Sakurai, T1
De Duve, C; Lazarow, PB1
Hassinen, IE; Jauhonen, VP; Savolainen, MJ1
Rognstad, R1
Eacho, PI; Foxworthy, PS; Hoover, DM; White, SL1
Horie, S; Ogawa, S; Suga, T; Watanabe, T; Yamada, J1
Haettinger, JR; Hutsell, TC; Mackerer, CR1
Cederbaum, AI; Rubin, E1
Kurup, CK; Panini, SR2
Haettinger, JR; Mackerer, CR1
McIntosh, DA; Topham, JC1
Norseth, J; Thomassen, MS1
Debeer, LJ; Mannaerts, GP1
De Saint Blanquat, G; Lamboeuf, Y1
Osmundsen, H1
Antonenkov, VD; Panchenko, LF1
Ishigami, M; Loo, Y; Sano, K; Sasaki, M; Shin, M; Umezawa, C; Yamashita, Y1
Fujita, Y; Kimura, A; Mori, Y; Sano, K; Shin, M; Umezawa, C; Yoshida, K1
Kondo, T; Marugami, M; Shibata, K; Umezawa, C1
Iwamoto, N; Sano, K; Shin, M; Umezawa, C; Yamashita, M1
Hashimoto, C; Nakakita, S; Sano, K; Shin, M; Umezawa, C1
Asada, S; Mizumori, N; Sano, K; Shin, M; Umezawa, C1
Sano, K; Shin, M; Umezawa, C1
Hammock, BD; Morisseau, C; Newman, JW; Watanabe, T1
Ohnishi, M; Sano, K; Shin, M; Umezawa, C1
Egashira, Y; Sanada, H; Sato, M; Shin, M; Sugawara, R; Tanabe, A1

Other Studies

28 other study(ies) available for clofibrate and nad

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Effects of ethyl p-chlorophenoxyisobutyrate on carbohydrate and fatty acid metabolism in rat liver.
    Journal of biochemistry, 1975, Volume: 78, Issue:6

    Topics: Animals; Body Weight; Carbohydrate Metabolism; Cholesterol; Clofibrate; Cytoplasm; Diet; Fatty Acids; Fructosephosphates; Gluconeogenesis; Glutamate Dehydrogenase; Glycerophosphates; Hexosediphosphates; Hydroxybutyrate Dehydrogenase; L-Lactate Dehydrogenase; Liver; Male; Mitochondria, Liver; NAD; Organ Size; Rats; Triglycerides

1975
A fatty acyl-CoA oxidizing system in rat liver peroxisomes; enhancement by clofibrate, a hypolipidemic drug.
    Proceedings of the National Academy of Sciences of the United States of America, 1976, Volume: 73, Issue:6

    Topics: Animals; Clofibrate; Coenzyme A; Liver; Microbodies; NAD; Organoids; Oxidation-Reduction; Palmitates; Rats

1976
Effects of clofibrate on ethanol-induced modifications in liver and adipose tissue metabolism: role of hepatic redox state and hormonal mechanisms.
    Biochemical pharmacology, 1977, Mar-01, Volume: 26, Issue:5

    Topics: Adipose Tissue; Animals; Clofibrate; Cyclic AMP; Dihydroxyacetone Phosphate; Ethanol; Fatty Acids, Nonesterified; Glycerophosphates; Kinetics; Lactates; Liver; Male; NAD; Oxidation-Reduction; Pyruvates; Rats

1977
Estimation of peroxisomal and mitochondrial fatty acid oxidation in rat hepatocytes using tritiated substrates.
    The Biochemical journal, 1991, Oct-01, Volume: 279 ( Pt 1)

    Topics: Animals; Clofibrate; Fatty Acids; Liver; Microbodies; NAD; Oxidation-Reduction; Rats; Substrate Specificity; Tritium

1991
Effect of ciprofibrate, bezafibrate, and LY171883 on peroxisomal beta-oxidation in cultured rat, dog, and rhesus monkey hepatocytes.
    Toxicology and applied pharmacology, 1990, Volume: 104, Issue:3

    Topics: Acetophenones; Animals; Autacoids; Azoles; Bezafibrate; Cells, Cultured; Clofibrate; Clofibric Acid; Dexamethasone; Dogs; Dose-Response Relationship, Drug; Female; Fibric Acids; Glucagon; Hypolipidemic Agents; In Vitro Techniques; Liver; Male; Microbodies; Microscopy, Electron; NAD; Oxidation-Reduction; Rats; Tetrazoles; Tyrosine Transaminase

1990
Participation of peroxisomes in the metabolism of xenobiotic acyl compounds: comparison between peroxisomal and mitochondrial beta-oxidation of omega-phenyl fatty acids in rat liver.
    Biochimica et biophysica acta, 1987, Sep-25, Volume: 921, Issue:2

    Topics: Acetyl Coenzyme A; Acyl-CoA Dehydrogenase, Long-Chain; Acyl-CoA Oxidase; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Clofibrate; Coenzyme A Ligases; Fatty Acids; Ketone Bodies; Lauric Acids; Liver; Male; Microbodies; Mitochondria, Liver; NAD; Oxidation-Reduction; Oxidoreductases; Rats; Rats, Inbred Strains

1987
Effects of clofibrate, in vitro, on mitochondrial respiration and oxidative phosphorylation.
    Biochemical pharmacology, 1973, Feb-15, Volume: 22, Issue:4

    Topics: Aniline Compounds; Animals; Ascorbic Acid; Butyrates; Clofibrate; Dinitrophenols; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mitochondria, Liver; NAD; Oxidative Phosphorylation; Oxygen Consumption; Polarography; Rats; Succinates; Vibration

1973
Effects of clofibrate on mitochondrial function.
    Biochemical pharmacology, 1974, Jul-15, Volume: 23, Issue:14

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Ascorbic Acid; Aspartic Acid; Calcium; Clofibrate; Energy Metabolism; Ethanol; Glycerophosphates; In Vitro Techniques; Ketoglutaric Acids; Malates; Membranes; Mitochondria, Liver; NAD; Oxidative Phosphorylation; Oxygen Consumption; Permeability; Phosphorus Radioisotopes; Rats; Succinates

1974
Cooperativity in the inhibition of oxidative phosphorylation by chlorophenoxyisobutyrate.
    Biochimica et biophysica acta, 1974, Oct-18, Volume: 368, Issue:1

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Allosteric Regulation; Animals; Binding Sites; Clofibrate; Electron Transport; Energy Transfer; Kinetics; Mathematics; Mitochondria, Liver; NAD; Oxidation-Reduction; Oxidative Phosphorylation; Protein Binding; Rats; Uncoupling Agents

1974
Mode of inhibition of mitochondrial energy transduction by chlorophenoxyisobutyrate.
    The Biochemical journal, 1974, Volume: 142, Issue:2

    Topics: Adenosine Triphosphatases; Animals; Clofibrate; Dinitrophenols; Electron Transport; Energy Transfer; Mitochondria, Liver; NAD; Oxidative Phosphorylation; Rats; Spectrophotometry; Subcellular Fractions; Succinates; Uncoupling Agents

1974
Further studies concerning the effects of clofibrate on respiration and oxidative phosphorylation of rat liver mitochondria.
    Biochemical pharmacology, 1974, Dec-01, Volume: 23, Issue:23

    Topics: Adenosine Diphosphate; Animals; Blood Glucose; Butyrates; Calcium; Cholesterol; Clofibrate; Fatty Acids, Nonesterified; Freezing; Growth; Hydroxybutyrates; In Vitro Techniques; Liver; Male; Mitochondria, Liver; Mitochondrial Swelling; NAD; Nucleotides; Organ Size; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen Consumption; Proteins; Rats; Rats, Inbred Strains; Stimulation, Chemical; Triglycerides

1974
A comparison of mouse and rat liver enzymes and their response to treatment with various compounds.
    Biochemical pharmacology, 1972, Apr-01, Volume: 21, Issue:7

    Topics: Aminopyrine; Animals; Carbon Tetrachloride; Chlorpromazine; Clofibrate; Cytochromes; DDT; Germ-Free Life; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Griseofulvin; L-Lactate Dehydrogenase; Liver; Mice; NAD; NADP; Organ Size; Oxidoreductases; Phenobarbital; Phosphogluconate Dehydrogenase; Rats; Species Specificity

1972
Stimulation of microperoxisomal beta-oxidation in rat heart by high-fat diets.
    Biochimica et biophysica acta, 1983, May-16, Volume: 751, Issue:3

    Topics: Animals; Clofibrate; Dietary Fats; Fatty Acids; Male; Microbodies; Myocardium; NAD; Organoids; Oxidation-Reduction; Palmitoyl Coenzyme A; Rats; Rats, Inbred Strains

1983
Mitochondrial and peroxisomal beta-oxidation of fatty acids in rat liver.
    Annals of the New York Academy of Sciences, 1982, Volume: 386

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Clofibrate; Coenzyme A; Fatty Acids; Kinetics; Liver; Microbodies; Mitochondria, Liver; NAD; Oleic Acid; Oleic Acids; Organoids; Oxidation-Reduction; Palmitic Acid; Palmitic Acids; Rats

1982
Effects of cyanamide and clofibrate on the enzymes of ethanol oxydation and on ethanol consumption in the rat.
    Archives internationales de pharmacodynamie et de therapie, 1980, Volume: 243, Issue:1

    Topics: Alcohol Drinking; Alcohol Oxidoreductases; Aldehyde Oxidoreductases; Animals; Catalase; Clofibrate; Cyanamide; Cyanides; Drinking Behavior; Ethanol; Male; NAD; Rats

1980
Factors which can influence beta-oxidation by peroxisomes isolated from livers of clofibrate treated rats. Some properties of peroxisomal fractions isolated in a self-generated Percoll gradient by vertical rotor centrifugation.
    The International journal of biochemistry, 1982, Volume: 14, Issue:10

    Topics: Animals; Centrifugation, Density Gradient; Chemical Phenomena; Chemistry; Clofibrate; Coenzyme A; Liver; Male; Microbodies; NAD; Organoids; Oxidation-Reduction; Rats; Rats, Inbred Strains

1982
[Induction of the activity of malate dehydrogenase (decarboxylating) and lactate dehydrogenase in the liver by clofibrate].
    Biulleten' eksperimental'noi biologii i meditsiny, 1981, Volume: 92, Issue:11

    Topics: Animals; Clofibrate; Cytosol; Dose-Response Relationship, Drug; Enzyme Induction; L-Lactate Dehydrogenase; Liver; Malate Dehydrogenase; Male; Microbodies; NAD; Rats; Rats, Inbred Strains; Time Factors

1981
Effect of feeding clofibrate-containing diet on the hepatic NAD+ level in rats.
    Journal of nutritional science and vitaminology, 1995, Volume: 41, Issue:3

    Topics: Animals; Clofibrate; Diet; Diethylhexyl Phthalate; Fenofibrate; Hypolipidemic Agents; Liver; Male; Microbodies; NAD; Rats; Rats, Sprague-Dawley

1995
NAD+ biosynthesis and metabolic fluxes of tryptophan in hepatocytes isolated from rats fed a clofibrate-containing diet.
    Biochemical pharmacology, 1996, Jul-26, Volume: 52, Issue:2

    Topics: Animals; Cells, Cultured; Clofibrate; Diet; Liver; Male; NAD; Niacin; Pentosyltransferases; Rats; Rats, Sprague-Dawley; Tryptophan

1996
Increased conversion ratio of tryptophan to niacin by the administration of clofibrate, a hypolipidemic drug, to rats.
    Bioscience, biotechnology, and biochemistry, 1996, Volume: 60, Issue:9

    Topics: Animals; Clofibrate; Hypolipidemic Agents; Liver; Male; NAD; Niacin; Niacinamide; Rats; Rats, Wistar; Tryptophan; Weaning; Weight Gain

1996
Pyridine nucleotide levels in liver of rats fed clofibrate- or pyrazinamide-containing diets.
    Biochemical pharmacology, 1998, Feb-01, Volume: 55, Issue:3

    Topics: Animals; Clofibrate; Diet; Female; Hypolipidemic Agents; Liver; Male; NAD; NADP; Pyrazinamide; Rats; Rats, Sprague-Dawley

1998
NAD+ biosynthesis from tryptophan in the presence of nicotinic acid or vice versa by rat hepatocytes--effect of clofibrate-feeding.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1998, Volume: 68, Issue:2

    Topics: Animals; Biological Transport; Clofibrate; Glutarates; Hydrolases; Liver; Male; Microbodies; NAD; Niacin; Rats; Rats, Sprague-Dawley; Tryptophan

1998
Effect of thioridazine or chlorpromazine on increased hepatic NAD+ level in rats fed clofibrate, a hypolipidaemic drug.
    The Journal of pharmacy and pharmacology, 1998, Volume: 50, Issue:4

    Topics: Animals; Antipsychotic Agents; Chlorpromazine; Clofibrate; Hypolipidemic Agents; Liver; Male; NAD; Rats; Rats, Sprague-Dawley; Thioridazine

1998
Effects of peroxisome-proliferators on the TRP-NAD pathway.
    Advances in experimental medicine and biology, 1999, Volume: 467

    Topics: Animals; Carboxy-Lyases; Cells, Cultured; Clofibrate; Female; Liver; Male; NAD; NADP; Niacin; Oxidation-Reduction; Pentosyltransferases; Peroxisome Proliferators; Peroxisomes; Phenothiazines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Tryptophan

1999
In vitro metabolism of the mammalian soluble epoxide hydrolase inhibitor, 1-cyclohexyl-3-dodecyl-urea.
    Drug metabolism and disposition: the biological fate of chemicals, 2003, Volume: 31, Issue:7

    Topics: Animals; Biotransformation; Chromatography, High Pressure Liquid; Clofibrate; Cyclohexanes; Cytochrome P-450 Enzyme System; Epoxide Hydrolases; Humans; Lauric Acids; Male; Mass Spectrometry; Microsomes, Liver; NAD; NADPH Dehydrogenase; Rats; Rats, Inbred F344; Solubility; Species Specificity; Time Factors; Urea

2003
NAD levels in the rat primary cultured hepatocytes affected by peroxisome-proliferators.
    Advances in experimental medicine and biology, 2003, Volume: 527

    Topics: Animals; Cells, Cultured; Clofibrate; Hepatocytes; NAD; Peroxisome Proliferators; Rats; Tryptophan

2003
Differential effects of pyrazinamide and clofibrate on gene expression of rat hepatic alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, a key enzyme of the tryptophan-NAD pathway.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 2006, Volume: 76, Issue:3

    Topics: Analysis of Variance; Animals; Antitubercular Agents; Carboxy-Lyases; Clofibrate; Diet, Fat-Restricted; Diet, Protein-Restricted; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Hypolipidemic Agents; Kidney; Liver; Male; Models, Animal; NAD; Peroxisome Proliferators; Pyrazinamide; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Time Factors; Transcription, Genetic; Tryptophan; Weight Gain

2006