clofibrate and metformin

clofibrate has been researched along with metformin in 20 studies

Research

Studies (20)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (50.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (5.00)	29.6817
2010's	9 (45.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Verstraete, M	1
Alberti, KG; Betteridge, DJ; Cudworth, AG; De Silva, SR; Shawe, JE	1
Chakrabarti, R; Fearnley, GR	1
Baggio, G; Baiocchi, MR; Briani, G; Crepaldi, G; Fellin, R	1
Bardfeld, PA; Bodian, JE; Hellman, L; Sachs, BA; Sugarman, LA	1
Gormsen, J; Laursen, B	2
Gormsen, J	1
Clarke, BF; Duncan, LJ	1
Fearnley, GR	1
Asai, M; Hashimoto, K; Iwasaki, Y; Kambayashi, M; Nishiyama, M; Taguchi, T; Takayasu, S; Tsugita, M; Yoshida, M	1

Reviews

3 review(s) available for clofibrate and metformin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
The position of long-term stimulation of the endogenous fibrinolytic system: present achievements and clinical perspectives. Thrombosis et diathesis haemorrhagica, 1975, Dec-15, Volume: 34, Issue:3 Topics: Adrenocorticotropic Hormone; Anabolic Agents; Androgens; Clofibrate; Coronary Disease; Deamino Arginine Vasopressin; Drug Therapy, Combination; Female; Fibrinolysis; Fibrinolytic Agents; Glucocorticoids; Humans; Inflammation; Male; Metformin; Phenformin; Plasminogen Activators; Postoperative Complications; Sulfonylurea Compounds; Thromboembolism; Thrombophlebitis; Vascular Diseases	1975
Advances in the treatment of diabetes mellitus. The Practitioner, 1971, Volume: 207, Issue:240 Topics: Blood Glucose; Chlorpropamide; Clofibrate; Diabetes Mellitus; Diabetic Coma; Diabetic Ketoacidosis; Diabetic Retinopathy; Diet Therapy; Humans; Hypoglycemia; Insulin; Kidney Transplantation; Lactates; Light Coagulation; Metformin; Methods; Pancreas Transplantation; Phenformin; Pituitary Gland; Renal Dialysis; Sulfonylurea Compounds; Tolbutamide	1971

Trials

2 trial(s) available for clofibrate and metformin

Article	Year
Metformin and clofibrate in maturity onset diabetes mellitus: advantages of combined treatment. Diabete & metabolisme, 1979, Volume: 5, Issue:3 Topics: Alanine; Blood Glucose; Cholesterol; Circadian Rhythm; Clofibrate; Diabetes Mellitus; Drug Synergism; Fibrinogen; Glycerol; Humans; Hydroxybutyrates; Lactates; Lipoproteins; Metformin; Triglycerides	1979
Liver scan in hyperlipoproteinemia. JAMA, 1974, Feb-25, Volume: 227, Issue:8 Topics: Adult; Aged; Aspartate Aminotransferases; Blood Protein Disorders; Blood Protein Electrophoresis; Cholesterol; Clinical Trials as Topic; Clofibrate; Colloids; Ethers, Cyclic; Female; Humans; Hyperlipidemias; Hypolipidemic Agents; Lipoproteins; Liver; Liver Diseases; Male; Metformin; Middle Aged; Oxandrolone; Phenotype; Placebos; Polyamines; Polymers; Radionuclide Imaging; Sulfur; Technetium; Triglycerides	1974

Article

Year

Metformin and clofibrate in maturity onset diabetes mellitus: advantages of combined treatment.

Diabete & metabolisme, 1979, Volume: 5, Issue:3

Topics: Alanine; Blood Glucose; Cholesterol; Circadian Rhythm; Clofibrate; Diabetes Mellitus; Drug Synergism; Fibrinogen; Glycerol; Humans; Hydroxybutyrates; Lactates; Lipoproteins; Metformin; Triglycerides

1979

Liver scan in hyperlipoproteinemia.

JAMA, 1974, Feb-25, Volume: 227, Issue:8

Topics: Adult; Aged; Aspartate Aminotransferases; Blood Protein Disorders; Blood Protein Electrophoresis; Cholesterol; Clinical Trials as Topic; Clofibrate; Colloids; Ethers, Cyclic; Female; Humans; Hyperlipidemias; Hypolipidemic Agents; Lipoproteins; Liver; Liver Diseases; Male; Metformin; Middle Aged; Oxandrolone; Phenotype; Placebos; Polyamines; Polymers; Radionuclide Imaging; Sulfur; Technetium; Triglycerides

1974

Other Studies

15 other study(ies) available for clofibrate and metformin

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR. European journal of medicinal chemistry, 2011, Volume: 46, Issue:1 Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics	2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Pharmacological fibrinolysis. Acta Universitatis Carolinae. Medica. Monographia, 1972, Volume: 52 Topics: Administration, Oral; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Clofibrate; Delayed-Action Preparations; Drug Resistance; Drug Therapy, Combination; Ethylestrenol; Female; Fibrin; Fibrinolysis; Humans; Male; Metformin; Methadone; Nandrolone; Phenformin; Stimulation, Chemical; Sulfonylurea Compounds; Testosterone; Time Factors	1972
[Treatment of hyperlipoproteinemias (author's transl)]. Giornale italiano di cardiologia, 1974, Volume: 4, Issue:3 Topics: Adolescent; Adult; Anticholesteremic Agents; Child; Cholestyramine Resin; Clofibrate; Dextrothyroxine; Female; Humans; Hypercholesterolemia; Hyperlipidemias; Ion Exchange Resins; Lipoproteins; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Metformin; Middle Aged; Nicotinic Acids; Phenformin	1974
Studies on pharmacological enhancement of blood fibrinolytic activity. Angiology, 1970, Volume: 21, Issue:8 Topics: Aged; Arteriosclerosis; Clofibrate; Female; Fibrinogen; Fibrinolysis; Fibrinolytic Agents; Humans; Immunodiffusion; Male; Metformin; Middle Aged; Plasminogen; Serum Globulins; Stimulation, Chemical; Testosterone; Thrombosis; Tolazamide	1970
Fibrinolytic activity and haemagglutination inhibition immunoassays. Scandinavian journal of haematology, 1970, Volume: 7, Issue:4 Topics: Adult; Aged; Biguanides; Clofibrate; Coronary Disease; Ethylestrenol; Female; Fibrin; Fibrinogen; Fibrinolysis; Hemagglutination Inhibition Tests; Hemostasis; Humans; Immunoassay; Immunodiffusion; Immunoelectrophoresis; Liver Cirrhosis; Male; Metformin; Middle Aged; Neoplasm Metastasis; Nicotinic Acids; Physical Exertion; Plasminogen; Prostatic Neoplasms; Stimulation, Chemical; Time Factors; Tolazamide	1970
[Physiological and pharmacological aspects of fibrinolysis]. La Clinica terapeutica, 1971, May-15, Volume: 57, Issue:3 Topics: Adrenal Cortex Hormones; Anabolic Agents; Arteriosclerosis Obliterans; Biguanides; Blood Coagulation Tests; Blood Platelets; Clofibrate; Coronary Disease; Diabetes Mellitus; Ethylestrenol; Fibrinolysis; Humans; Insulin; Metformin; Myocardial Infarction; Phenformin; Sulfonylurea Compounds; Testosterone; Thrombosis	1971
Pharmacological enhancement and short-term stimulation of blood fibrinolytic activity. Scandinavian journal of haematology, 1969, Volume: 6, Issue:6 Topics: Adolescent; Adult; Aged; Aminocaproates; Anticholesteremic Agents; Arteriosclerosis; Arthritis, Rheumatoid; Asthma; Clofibrate; Diabetes Mellitus; Female; Fibrinogen; Fibrinolysis; Humans; Hypoglycemic Agents; Immunoassay; Intermittent Claudication; Kidney Failure, Chronic; Liver Cirrhosis; Lung Neoplasms; Male; Metformin; Middle Aged; Neoplasm Metastasis; Nicotinic Acids; Phlebitis; Physical Exertion; Plasminogen; Primary Myelofibrosis; Propionates; Pulmonary Heart Disease; Testosterone; Tolazamide; Urea	1969
Is the metabolic syndrome an intracellular Cushing state? Effects of multiple humoral factors on the transcriptional activity of the hepatic glucocorticoid-activating enzyme (11beta-hydroxysteroid dehydrogenase type 1) gene. Molecular and cellular endocrinology, 2008, Mar-26, Volume: 285, Issue:1-2 Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Anticholesteremic Agents; Base Sequence; Cell Line; Chromans; Clofibrate; Cortisone; Cushing Syndrome; Dexamethasone; Gene Expression Regulation, Enzymologic; Glucocorticoids; Humans; Hydrocortisone; Hypoglycemic Agents; Insulin; Interleukin-1beta; Liver; Metabolic Syndrome; Metformin; Molecular Sequence Data; Receptors, Glucocorticoid; Thiazolidinediones; Transcription Factor AP-1; Troglitazone; Tumor Necrosis Factor-alpha	2008