clofibrate has been researched along with leucine in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (76.47) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 2 (11.76) | 29.6817 |
| 2010's | 1 (5.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Coloma, L; Koenig, C; Leighton, F | 1 |
| Kumar, NS; Reddy, JK | 1 |
| Germershausen, JI; Greenspan, MD; Mackow, R | 1 |
| Suzuki, K | 1 |
| Brass, EP | 1 |
| Capuzzi, DM; Margolis, S | 1 |
| Maragoudakis, ME | 1 |
| Eder, HA; Roheim, PS; Segal, P | 1 |
| Albert, AD; Bednarek, JM; Gear, AR | 1 |
| Dvornik, D; Hill, P | 1 |
| Glatz, JF; van Moerkerk, HT; Veerkamp, JH; Wagenmakers, AJ | 1 |
| Blum, JJ | 1 |
| Casanello-Ertl, D; Duducgian-Vartavarian, L; Pardridge, WM | 1 |
| Adibi, SA; Paul, HS | 1 |
| Bajotto, G; Goto, H; Hayashi, K; Honda, T; Ishigami, M; Ishiguro, H; Katano, Y; Maeda, K; Nakano, I; Shimomura, Y | 1 |
| Kawano, F; Nakai, N; Ohira, T; Ohira, Y; Oke, Y; Terada, M | 1 |
17 other study(ies) available for clofibrate and leucine
| Article | Year |
|---|---|
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Structure, composition, physical properties, and turnover of proliferated peroxisomes. A study of the trophic effects of Su-13437 on rat liver.
Topics: Acid Phosphatase; Animals; Antigens; Catalase; Cell Fractionation; Clofibrate; D-Amino-Acid Oxidase; Female; Histocytochemistry; Hydroxy Acids; Leucine; Liver; Male; Microbodies; Nafenopin; Organoids; Oxidoreductases; Propionates; Protein Biosynthesis; Rats; Urate Oxidase | 1975 |
Stimulation of catalase synthesis and increase of carnitine acetyltransferase activity in the liver of intact female rats fed clofibrate.
Topics: Acetyltransferases; Animals; Antigens; Carnitine O-Acetyltransferase; Catalase; Clofibrate; Female; Leucine; Liver; Male; Microbodies; Organ Size; Proteins; Rats | 1979 |
Effect of halofenate and clofibrate on lipid synthesis in rat adipocytes.
Topics: Adipose Tissue; Animals; Citrates; Clofibrate; Fatty Acids; Glucose; Glycolates; Halofenate; In Vitro Techniques; Kynurenic Acid; Leucine; Oleic Acids; Palmitic Acids; Peptides; Pyruvates; Rats | 1975 |
Effects of S-8527 (1,1-bis(4'-(1'-carboxy-1'-methylpropoxy)phenyl) cyclohexane), a new hypolipidemic compound, on cholesterol and lipoprotein metabolism in rats.
Topics: Acetates; Animals; Cholesterol; Clofibrate; Cyclohexanes; Glycolates; Hypolipidemic Agents; In Vitro Techniques; Intestinal Mucosa; Leucine; Lipoproteins; Liver; Male; Mevalonic Acid; Phenoxyacetates; Rats | 1976 |
Translation rates of isolated liver mitochondria under conditions of hepatic mitochondrial proliferation.
Topics: Animals; Clofibrate; DNA, Mitochondrial; Hydroxocobalamin; Kinetics; Leucine; Male; Methionine; Methylmalonyl-CoA Mutase; Mitochondria, Liver; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Vitamin B 12 | 1992 |
Metabolic studies in isolated rat liver cells. II. Biosynthesis of serum low density lipoproteins and its regulation.
Topics: Acetates; Animals; Antigens; Buffers; Carbon Isotopes; Carrier Proteins; Chlorides; Clofibrate; Depression, Chemical; Dietary Fats; Goats; Immune Sera; Immunodiffusion; Immunoelectrophoresis; Leucine; Lipids; Lipoproteins; Liver; Magnesium; Metabolism; Niacinamide; Phosphates; Precipitin Tests; Protein Biosynthesis; Puromycin; Rabbits; Rats; Stimulation, Chemical; Succinates; Time Factors; Triglycerides; Tromethamine; Ultracentrifugation | 1971 |
On the mode of action of lipid-lowering agents. VI. Inhibition of lipogenesis in rat mammary gland cell culture.
Topics: Acetates; Animals; Anticholesteremic Agents; Carbon Dioxide; Carbon Isotopes; Cell Line; Cell Membrane Permeability; Cholesterol; Chromatography; Chromatography, Thin Layer; Citrates; Clofibrate; Coenzyme A; Culture Techniques; Depression, Chemical; Fatty Acids, Nonesterified; Female; Glucose; Leucine; Ligases; Lipid Metabolism; Lipids; Magnesium; Malonates; Mammary Glands, Animal; Mevalonic Acid; Naphthalenes; Palmitic Acids; Phenols; Propionates; Rats; Silicon Dioxide | 1971 |
Effect of clofibrate on lipoprotein metabolism in hyperlipidemic rats.
Topics: Animals; Carbon Isotopes; Clofibrate; Depression, Chemical; Dietary Carbohydrates; Hyperlipidemias; Leucine; Lipoproteins; Lipoproteins, VLDL; Male; Phospholipids; Rats; Sucrose; Triglycerides; Tritium | 1972 |
The effect of the hypocholesterolemic drug clofibrate on liver mitochondrial biogenesis. A role for neutral mitochondrial proteases.
Topics: Acid Phosphatase; Animals; Arginine; Carbon Radioisotopes; Clofibrate; Cytochrome Reductases; DNA; Electron Transport Complex IV; Hepatectomy; Leucine; Liver; Lysosomes; Malate Dehydrogenase; Male; Methionine; Mitochondria, Liver; Mixed Function Oxygenases; Monoamine Oxidase; Oxygen Consumption; Protease Inhibitors; Rats; RNA; Rotenone; Sulfur Radioisotopes | 1974 |
Agents affecting lipid metabolism. XL. Effect of ethyl chlorophenoxyisobutyrate on liver lipids and serum lipoproteins in rats.
Topics: Acetates; Animals; Carbon Isotopes; Cholesterol; Choline; Chromatography, Gas; Citrates; Clofibrate; Fatty Acids; Fatty Acids, Essential; Female; Glucose; Glycerol; In Vitro Techniques; Kinetics; Leucine; Lipids; Lipoproteins; Liver; Male; Mevalonic Acid; Organ Size; Palmitic Acids; Phospholipids; Protein Biosynthesis; Rats; Sex Factors; Sodium; Triglycerides; Tritium | 1971 |
Effect of clofibrate feeding on palmitate and branched-chain 2-oxo acid oxidation in rat liver and muscle.
Topics: Animals; Citrate (si)-Synthase; Clofibrate; Electron Transport Complex IV; Keto Acids; Kinetics; Leucine; Liver; Male; Muscles; Oxidation-Reduction; Palmitic Acid; Palmitic Acids; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1983 |
Effect of clofibrate on CO2 fixation into glycogen and fatty acids via the leucine catabolism pathway in Tetrahymena.
Topics: Acetates; Animals; Carbohydrate Metabolism; Carbon Dioxide; Clofibrate; Fatty Acids; Glycogen; Leucine; Tetrahymena pyriformis; Tyrosine | 1980 |
Branched chain amino acid oxidation in cultured rat skeletal muscle cells. Selective inhibition by clofibric acid.
Topics: Amino Acids, Branched-Chain; Animals; Cells, Cultured; Clofibrate; Clofibric Acid; Kinetics; Leucine; Muscles; Oxidation-Reduction; Rats | 1980 |
Leucine oxidation and protein turnover in clofibrate-induced muscle protein degradation in rats.
Topics: Administration, Oral; Amino Acids, Branched-Chain; Animals; Biological Transport; Clofibrate; Leucine; Liver; Male; Muscle Proteins; Muscles; Oxidation-Reduction; Rats | 1980 |
Clofibrate treatment promotes branched-chain amino acid catabolism and decreases the phosphorylation state of mTOR, eIF4E-BP1, and S6K1 in rat liver.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Amino Acids, Branched-Chain; Animals; Carrier Proteins; Clofibrate; Hypolipidemic Agents; Intracellular Signaling Peptides and Proteins; Leucine; Liver; Male; Multienzyme Complexes; Phosphoproteins; Phosphorylation; Protein Kinases; Rats; Ribosomal Protein S6 Kinases, 90-kDa; TOR Serine-Threonine Kinases | 2006 |
Effects of peroxisome proliferator-activated receptor alpha (PPARalpha) agonists on leucine-induced phosphorylation of translational targets in C2C12 cells.
Topics: Adaptor Proteins, Signal Transducing; AMP-Activated Protein Kinases; Animals; Carrier Proteins; Cell Cycle Proteins; Cell Line; Clofibrate; Elongation Factor 2 Kinase; Eukaryotic Initiation Factors; Flavonoids; Leucine; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Multienzyme Complexes; p38 Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; PPAR alpha; Protein Biosynthesis; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Pyrimidines; Ribosomal Protein S6; Ribosomal Protein S6 Kinases, 70-kDa; Sirolimus | 2008 |