clofibrate and indomethacin

clofibrate has been researched along with indomethacin in 25 studies

Research

Studies (25)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (36.00)	18.7374
1990's	2 (8.00)	18.2507
2000's	3 (12.00)	29.6817
2010's	11 (44.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Strassburg, CP; Tukey, RH	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Vértesi, C; Virág, S; Welner, I	1
Ciammaichella, A	1
Dulik, DM; Fenselau, CC; van Breemen, RB	1
Hucker, HB; Stauffer, SC; White, SE	1
Flower, R; Gryglewski, R; Herbaczyńska-Cedro, K; Vane, JR	1
Vargaftig, BB; Zirinis, P	1
Storey, GO	1
Barre, J; D'Athis, P; Tillement, JP; Zini, R	1
Brooks, PM; Meffin, PJ; Veenendaal, JR	1
Robinson, AG; Verbalis, JG	1
Benet, LZ; Lin, ET; Mizuma, T	1

Reviews

2 review(s) available for clofibrate and indomethacin

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for clofibrate and indomethacin

Article	Year
Combined vessel injuring action of adjuvant arthritis and cholesterol diet. (III. Action of Chinoin-123 on a new model of experimental atherosclerosis of rat). Therapia Hungarica (English edition), 1978, Volume: 26, Issue:4 Topics: Animals; Arteriosclerosis; Arthritis; Arthritis, Experimental; Cholesterol, Dietary; Clinical Trials as Topic; Clofibrate; Indomethacin; Male; Pyridines; Pyrimidines; Rats; Sodium Salicylate	1978

Article

Year

Combined vessel injuring action of adjuvant arthritis and cholesterol diet. (III. Action of Chinoin-123 on a new model of experimental atherosclerosis of rat).

Therapia Hungarica (English edition), 1978, Volume: 26, Issue:4

Topics: Animals; Arteriosclerosis; Arthritis; Arthritis, Experimental; Cholesterol, Dietary; Clinical Trials as Topic; Clofibrate; Indomethacin; Male; Pyridines; Pyrimidines; Rats; Sodium Salicylate

1978

Other Studies

22 other study(ies) available for clofibrate and indomethacin

Article	Year
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR. European journal of medicinal chemistry, 2011, Volume: 46, Issue:1 Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
[Current status of vascular diseases and their treatment]. La Clinica terapeutica, 1979, Feb-28, Volume: 88, Issue:4 Topics: Arteriosclerosis; Aspirin; Clofibrate; Humans; Indomethacin; Sulfinpyrazone; Vasodilator Agents	1979
Activated phase II metabolites: comparison of alkylation by 1-O-acyl glucuronides and acyl sulfates. Advances in experimental medicine and biology, 1986, Volume: 197 Topics: Acylation; Alkylation; Animals; Biotransformation; Clofibrate; Drug Stability; Flufenamic Acid; Glucuronates; Glucuronosyltransferase; Half-Life; Hydrogen-Ion Concentration; Indomethacin; Kinetics; Liver; Rabbits; Sulfates	1986
Effect of halofenate on binding of various drugs to human plasma proteins and on the plasma half-life of antipyrine in monkeys. Journal of pharmaceutical sciences, 1972, Volume: 61, Issue:9 Topics: Acetamides; Animals; Anticholesteremic Agents; Antipyrine; Aspirin; Blood Proteins; Carbon Isotopes; Chlorothiazide; Clofibrate; Dicumarol; Digitoxin; Drug Interactions; Fluorine; Glycolates; Half-Life; Haplorhini; Humans; Hypolipidemic Agents; Indomethacin; Macaca; Phenothiazines; Phenylbutazone; Salicylates; Warfarin	1972
Effects of anti-inflammatory drugs on prostaglandin biosynthesis. Nature: New biology, 1972, Jul-26, Volume: 238, Issue:82 Topics: Acetaminophen; Aldosterone; Animals; Anti-Inflammatory Agents; Aspirin; Azathioprine; Benzoates; Biological Assay; Clofibrate; Dexamethasone; Dogs; Edema; Fludrocortisone; Hydrocortisone; In Vitro Techniques; Indomethacin; Mefenamic Acid; Oxygenases; Phenylbutazone; Prostaglandins; Rats; Spleen; Triamcinolone Acetonide	1972
Platelet aggregation induced by arachidonic acid is accompanied by release of potential inflammatory mediators distinct from PGE2 and PGF2. Nature: New biology, 1973, Jul-25, Volume: 244, Issue:134 Topics: Acetaminophen; Anti-Inflammatory Agents; Aorta; Arachidonic Acids; Aspirin; Biological Assay; Blood Platelets; Clofibrate; Glycerol; Indomethacin; Inflammation; Phenylbutazone; Platelet Adhesiveness; Prostaglandins; Tissue Extracts; Vasoconstrictor Agents	1973
Xanthomatosis, hyperlipoproteinaemia (type II, Fredrickson), gout, cardiac infarction. Proceedings of the Royal Society of Medicine, 1971, Volume: 64, Issue:1 Topics: Adult; Cholesterol; Clofibrate; Gout; Humans; Hyperlipidemias; Indomethacin; Lipoproteins; Male; Myocardial Infarction; Xanthomatosis	1971
Binding of clometacin to human serum albumin. Interactions with clofibrate, indomethacin, salicylic acid and warfarin. Biochemical pharmacology, 1983, Oct-01, Volume: 32, Issue:19 Topics: Analgesics; Clofibrate; Humans; Indoleacetic Acids; Indomethacin; Kinetics; Protein Binding; Salicylates; Salicylic Acid; Serum Albumin; Structure-Activity Relationship; Warfarin	1983
Probenecid-clofibrate interaction. Clinical pharmacology and therapeutics, 1981, Volume: 29, Issue:3 Topics: Adolescent; Adult; Clofibrate; Drug Interactions; Female; Glucuronates; Humans; Indomethacin; Metabolic Clearance Rate; Probenecid; Protein Binding	1981
Diabetes insipidus. Current therapy in endocrinology and metabolism, 1994, Volume: 5 Topics: Benzothiadiazines; Carbamazepine; Chlorpropamide; Clofibrate; Diabetes Insipidus; Diuretics; Female; Humans; Indomethacin; Life Style; Pregnancy; Pregnancy Complications; Sodium Chloride Symporter Inhibitors; Thirst; Vasopressins; Water	1994
Preparative chromatography of furosemide 1-O-acyl-glucuronide from urine using micronized amberiite XAD-2 and its application to other 1-O-acyl-glucuronides. Preparative biochemistry & biotechnology, 1998, Volume: 28, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzimidazoles; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Clofibrate; Flufenamic Acid; Furosemide; Glucuronates; Glucuronidase; Indomethacin; Mass Spectrometry; Molecular Structure; Probenecid; Tolmetin	1998