Compounds > clofibrate

clofibrate and fenofibric acid

clofibrate has been researched along with fenofibric acid in 15 studies

Research

Studies (15)

Timeframe	Studies, this research(%)	All Research%
pre-1990	8 (53.33)	18.7374
1990's	4 (26.67)	18.2507
2000's	2 (13.33)	29.6817
2010's	1 (6.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chuang, S; Horne, J; Porter, CJ; Scanlon, MJ; Velkov, T	1
Chalmers, DK; Chuang, S; Horne, J; Porter, CJ; Scanlon, MJ; Velkov, T; Wielens, J	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Fournel, S; Magdalou, J; Pinon, P; Siest, G	1
Bakir, R; Chanu, B; Djian, F; Goy-Loeper, J; Rouffy, J	1
Santafé Oroz, J; Segarra Domènech, J	1
Harvengt, C; Heller, F	1
Daubresse, JC	1
Lehmann-Leo, W; Luley, C; Scheffler, W; Schilling, A; Schwartzkopff, W; Wegscheider, K	1
Alsasua, MT; Cepeda, L; Gómez, MP	1
Lutz, WK; Schlatter, C; von Däniken, A	1
Ishigami, M; Loo, Y; Sano, K; Sasaki, M; Shin, M; Umezawa, C; Yamashita, Y	1
Betteridge, L; Chan, P; Gallagher, K; Munro, E; Patel, M; Schachter, M; Sever, P; Wolfe, J	1
Kockx, M; Kooistra, T; Princen, HM	1
Derudas, B; Gervois, PP; Gonzalez, FJ; Kockx, M; Kooistra, T; Peters, JM; Poulain, P; Princen, HM; Staels, B	1

Reviews

2 review(s) available for clofibrate and fenofibric acid

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Pharmacologic therapy of atherosclerosis (I). Current possibilities]. Medicina clinica, 1983, Nov-26, Volume: 81, Issue:17 Topics: Anticholesteremic Agents; Arteriosclerosis; Cholesterol; Clofibrate; Clofibric Acid; Fenofibrate; Gemfibrozil; Glycosaminoglycans; Humans; Ion Exchange Resins; Lipoproteins; Nicotinic Acids; Pentanoic Acids; Probucol	1983

Trials

3 trial(s) available for clofibrate and fenofibric acid

Article	Year
Comparative evaluation of the effects of ciprofibrate and fenofibrate on lipids, lipoproteins and apoproteins A and B. Atherosclerosis, 1985, Volume: 54, Issue:3 Topics: Adult; Apolipoproteins A; Apolipoproteins B; Clofibrate; Clofibric Acid; Drug Evaluation; Female; Fenofibrate; Fibric Acids; Humans; Hyperlipoproteinemia Type II; Lipids; Lipoproteins; Male; Propionates; Time Factors	1985
A comparison of fenofibrate and clofibrate hypolipidemic effects. Acta clinica Belgica, 1980, Volume: 35, Issue:4 Topics: Anticholesteremic Agents; Cholesterol; Clinical Trials as Topic; Clofibrate; Fenofibrate; Humans; Hyperlipidemias; Middle Aged; Propionates; Triglycerides	1980
[Efficacy of bezafibrate and fenofibrate on elevated blood lipids in HLP type IIa, IIb and IV]. Die Medizinische Welt, 1982, Apr-30, Volume: 33, Issue:17 Topics: Adult; Aged; Anticholesteremic Agents; Bezafibrate; Clofibrate; Clofibric Acid; Female; Fenofibrate; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Hypolipidemic Agents; Lipids; Male; Middle Aged; Propionates	1982

Other Studies

10 other study(ies) available for clofibrate and fenofibric acid

Article	Year
Characterization of the drug binding specificity of rat liver fatty acid binding protein. Journal of medicinal chemistry, 2008, Jul-10, Volume: 51, Issue:13 Topics: Anilino Naphthalenesulfonates; Animals; Fatty Acid-Binding Proteins; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Fluorescence; Substrate Specificity	2008
Probing the fibrate binding specificity of rat liver fatty acid binding protein. Journal of medicinal chemistry, 2009, Sep-10, Volume: 52, Issue:17 Topics: Animals; Binding Sites; Carboxylic Acids; Clofibric Acid; Esters; Fatty Acid-Binding Proteins; Fenofibrate; Hypolipidemic Agents; Ligands; Liver; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Rats; Spectrometry, Fluorescence; Substrate Specificity; Temperature; Thermodynamics	2009
Differential induction profile of drug-metabolizing enzymes after treatment with hypolipidaemic agents. Xenobiotica; the fate of foreign compounds in biological systems, 1987, Volume: 17, Issue:4 Topics: Animals; Biphenyl Compounds; Body Weight; Butyrophenones; Clofibrate; Clofibric Acid; Cytochrome P-450 Enzyme System; Enzyme Induction; Epoxide Hydrolases; Fenofibrate; gamma-Glutamyltransferase; Glucuronosyltransferase; Hypolipidemic Agents; Lipids; Liver; Male; Rats; Rats, Inbred Strains; Structure-Activity Relationship	1987
Effects of clofibrate, bezafibrate, fenofibrate and probucol on plasma lipolytic enzymes in normolipaemic subjects. European journal of clinical pharmacology, 1983, Volume: 25, Issue:1 Topics: Adult; Bezafibrate; Cholesterol; Clofibrate; Fenofibrate; Humans; Hypolipidemic Agents; Lipase; Lipolysis; Lipoprotein Lipase; Male; Phosphatidylcholine-Sterol O-Acyltransferase; Probucol; Triglycerides	1983
[Hypolipemic action of various drugs in rats poisoned with Triton WR 1339]. Revista espanola de fisiologia, 1982, Volume: 38 Suppl Topics: Animals; Cholesterol; Clofibrate; Fenofibrate; Hypolipidemic Agents; Lipids; Male; Nicotinic Acids; Polyethylene Glycols; Pyridinolcarbamate; Rats	1982
Lack of covalent binding to rat liver DNA of the hypolipidemic drugs clofibrate and fenofibrate. Toxicology letters, 1981, Volume: 7, Issue:4-5 Topics: Animals; Carcinogens; Clofibrate; DNA; Female; Fenofibrate; Liver; Male; Propionates; Protein Binding; Rats	1981
Effect of feeding clofibrate-containing diet on the hepatic NAD+ level in rats. Journal of nutritional science and vitaminology, 1995, Volume: 41, Issue:3 Topics: Animals; Clofibrate; Diet; Diethylhexyl Phthalate; Fenofibrate; Hypolipidemic Agents; Liver; Male; Microbodies; NAD; Rats; Rats, Sprague-Dawley	1995
Growth inhibition of human vascular smooth muscle cells by fenofibrate: a possible therapy for restenosis. Cardiovascular research, 1994, Volume: 28, Issue:5 Topics: Bezafibrate; Cell Division; Cells, Cultured; Clofibrate; Fenofibrate; Gemfibrozil; Graft Occlusion, Vascular; Humans; Muscle, Smooth; Platelet-Derived Growth Factor; Saphenous Vein	1994
Fibrate-modulated expression of fibrinogen, plasminogen activator inhibitor-1 and apolipoprotein A-I in cultured cynomolgus monkey hepatocytes -- role of the peroxisome proliferator-activated receptor-alpha. Thrombosis and haemostasis, 1998, Volume: 80, Issue:6 Topics: 5,8,11,14-Eicosatetraynoic Acid; Alitretinoin; Animals; Apolipoprotein A-I; Cells, Cultured; Clofibrate; Clofibric Acid; Dimerization; Female; Fenofibrate; Fibric Acids; Fibrinogen; Gemfibrozil; Gene Expression Regulation; Genes, Reporter; Hypolipidemic Agents; Liver; Macaca fascicularis; Male; Peroxisome Proliferators; Plasminogen Activator Inhibitor 1; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Transcription Factors; Transcriptional Activation; Tretinoin	1998
Fibrates suppress fibrinogen gene expression in rodents via activation of the peroxisome proliferator-activated receptor-alpha. Blood, 1999, May-01, Volume: 93, Issue:9 Topics: Animals; Cells, Cultured; Clofibrate; Clofibric Acid; DNA-Binding Proteins; Fenofibrate; Fibric Acids; Fibrinogen; Gene Expression Regulation; Hypolipidemic Agents; Kinetics; Liver; Male; Mice; Mice, Knockout; Peroxisome Proliferators; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Transcription Factors; Transcription, Genetic; Triglycerides	1999