clofibrate has been researched along with diethylnitrosamine in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (52.38) | 18.7374 |
| 1990's | 7 (33.33) | 18.2507 |
| 2000's | 2 (9.52) | 29.6817 |
| 2010's | 1 (4.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rao, MS; Reddy, JK | 1 |
| Aoki, T; Hakoi, K; Ito, N; Kato, T; Ozaki, K; Sato, K; Tsuda, H; Uwagawa, S; Yamaguchi, S | 1 |
| Appelkvist, EL; Dallner, G; Kalén, A | 1 |
| Kitagawa, T; Lee, GH; Nomura, K | 1 |
| Aoki, T; Hosokawa, S; Igarashi, T; Ito, N; Nakanowatari, J; Tatematsu, M | 1 |
| Bridges, JW; Greaves, P; Irisarri, E; Mompon, P; Monro, AM | 1 |
| Garvey, LK; Hamm, TE; Popp, JA; Swenberg, JA | 1 |
| Greaves, P; Irisarri, E; Monro, AM | 1 |
| Beer, D; Coloma, J; Glauert, HP; Goldsworthy, TL; Pitot, HC; Rao, MS; Schwarz, M; Xu, YD | 1 |
| Hayashi, Y; Imazawa, T; Kurokawa, Y; Matushima, Y; Takamura, N | 1 |
| Nagarajan, B; Nagini, S | 1 |
| Furukawa, K; Mochizuki, Y; Sawada, N | 2 |
| Cattley, RC; Kato, M; Popp, JA; Teets, VJ; Voss, KS | 1 |
| Asamoto, M; de Camargo, JL; Ito, N; Nagase, S; Tagawa, Y; Tsuda, H; Wada, S | 1 |
| Asamoto, M; Baba-Toriyama, H; Hori, T; Iwahori, Y; Kim, DJ; Krutovskikh, VA; Mutai, M; Ota, T; Takasuka, N; Tatematsu, M; Tsuchiya, T; Tsuda, H; Uehara, N; Yamasaki, H | 1 |
| Hong, JT; Kim, DJ; Lee, KK | 1 |
| Hirose, M; Imazawa, T; Mitsumori, K; Onodera, H; Shoda, T; Toyoda, K; Uneyama, C | 1 |
| Fukushima, S; Kikuchi, K; Kushida, M; Mikami, N; Morimura, K; Oeda, K; Okuno, Y; Ozaki, K; Saito, K; Sukata, T; Sumida, K; Uwagawa, S | 1 |
| Bannasch, P; Groos, J; Kopp-Schneider, A; Schwarz, M | 1 |
| Fukushima, K; Fukushima, N; Hirane, M; Honoki, K; Ishii, S; Takahashi, K; Tomimatsu, A; Tsujiuchi, T | 1 |
21 other study(ies) available for clofibrate and diethylnitrosamine
| Article | Year |
|---|---|
Enhancement by Wy-14,643, a hepatic peroxisome proliferator, of diethylnitrosamine-initiated hepatic tumorigenesis in the rat.
Topics: Acetates; Animals; Cell Division; Clofibrate; Diethylnitrosamine; Drug Synergism; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Nitrosamines; Pyrimidines; Rats; Rats, Inbred F344 | 1978 |
Effects of modifying agents on conformity of enzyme phenotype and proliferative potential in focal preneoplastic and neoplastic liver cell lesions in rats.
Topics: Adenosine Triphosphatases; Animals; Bromodeoxyuridine; Cell Division; Clofibrate; Diethylhexyl Phthalate; Diethylnitrosamine; Ethoxyquin; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Glutathione Transferase; Isoenzymes; Liver Neoplasms, Experimental; Male; Phenobarbital; Phenotype; Precancerous Conditions; Rats; Rats, Inbred F344; Tumor Cells, Cultured | 1992 |
The effects of inducers of the endoplasmic reticulum, peroxisomes and mitochondria on the amounts and synthesis of ubiquinone in rat liver subcellular membranes.
Topics: Animals; Cholesterol, Dietary; Cholestyramine Resin; Chromatography, High Pressure Liquid; Clofibrate; Diethylhexyl Phthalate; Diethylnitrosamine; Dolichols; Endoplasmic Reticulum; Intracellular Membranes; Liver; Methylcholanthrene; Mevalonic Acid; Microbodies; Microsomes, Liver; Mitochondria, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Ubiquinone | 1990 |
Comparative study of diethylnitrosamine-initiated two-stage hepatocarcinogenesis in C3H, C57BL and BALB mice promoted by various hepatopromoters.
Topics: Animals; Clofibrate; Diethylnitrosamine; Ethinyl Estradiol; Liver; Liver Neoplasms, Experimental; Liver Regeneration; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Phenobarbital; Species Specificity | 1989 |
Modulation of diethylnitrosamine-initiated placental glutathione S-transferase positive preneoplastic and neoplastic lesions by clofibrate, a hepatic peroxisome proliferator.
Topics: Animals; Body Weight; Clofibrate; Diethylnitrosamine; Female; Glutathione Transferase; Immunoenzyme Techniques; Isoenzymes; Liver; Liver Neoplasms, Experimental; Liver Regeneration; Male; Microbodies; Organ Size; Placenta; Precancerous Conditions; Pregnancy; Rats; Rats, Inbred F344 | 1989 |
A cytochemical study of the livers of rats treated with diethylnitrosamine/phenobarbital, with benzidine/phenobarbital, with phenobarbital, or with clofibrate.
Topics: Administration, Oral; Animals; Benzidines; Clofibrate; Diethylnitrosamine; Drug Interactions; Glucose-6-Phosphatase; Injections, Intraperitoneal; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains | 1987 |
Lack of hepatic promotional activity by the peroxisomal proliferating hepatocarcinogen di(2-ethylhexyl)phthalate.
Topics: Animals; Cell Division; Clofibrate; Diethylhexyl Phthalate; Diethylnitrosamine; Female; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Microbodies; Phthalic Acids; Rats; Rats, Inbred Strains | 1985 |
Hepatic foci of cellular and enzymatic alteration and nodules in rats treated with clofibrate or diethylnitrosamine followed by phenobarbital: their rate of onset and their reversibility.
Topics: Animals; Body Weight; Clofibrate; Diethylnitrosamine; gamma-Glutamyltransferase; Glucosephosphate Dehydrogenase; Histocytochemistry; Hyperplasia; Liver; Liver Neoplasms, Experimental; Male; Organ Size; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred Strains | 1986 |
Induction of altered hepatic foci in rats by the administration of hypolipidemic peroxisome proliferators alone or following a single dose of diethylnitrosamine.
Topics: Adenosine Triphosphatases; Animals; Clofibrate; Clofibric Acid; Diethylnitrosamine; Drug Administration Schedule; Fibric Acids; gamma-Glutamyltransferase; Glucose-6-Phosphatase; Hepatectomy; Immunologic Techniques; Liver; Microbodies; Pyrimidines; Rats; Time Factors | 1986 |
Promoting effect of peroxisome proliferators in two-stage rat renal tumorigenesis.
Topics: Animals; Clofibrate; Cocarcinogenesis; Diethylhexyl Phthalate; Diethylnitrosamine; Kidney Neoplasms; Male; Microbodies; Rats; Rats, Inbred F344 | 1988 |
Hypolipidemic drug clofibrate promotes hepatic tumor.
Topics: Animals; Carcinogenicity Tests; Clofibrate; Diethylnitrosamine; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred Strains | 1988 |
Effect of simultaneous administration of clofibrate with diethylnitrosamine on hepatic tumorigenesis in the rat.
Topics: Animals; Clofibrate; Cocarcinogenesis; Diethylnitrosamine; Dose-Response Relationship, Drug; Liver Neoplasms, Experimental; Male; Nitrosamines; Rats; Rats, Inbred F344 | 1983 |
Effects of various concentrations of ethyl-alpha-p-chlorophenoxyisobutyrate (clofibrate) on diethylnitrosamine-induced hepatic tumorigenesis in the rat.
Topics: Animals; Body Weight; Clofibrate; Cocarcinogenesis; Diethylnitrosamine; Dose-Response Relationship, Drug; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Rats | 1982 |
Initiator-specific promotion of hepatocarcinogenesis by WY-14,643 and clofibrate.
Topics: 2-Acetylaminofluorene; Animals; Clofibrate; Diethylnitrosamine; Liver Neoplasms, Experimental; Male; Microbodies; Pyrimidines; Rats; Rats, Inbred F344 | 1994 |
Modifying effects of chemicals on the development of liver preneoplastic placental glutathione S-transferase positive foci in analbuminemic and Sprague-Dawley rats.
Topics: Acetylglucosaminidase; Animals; Butylated Hydroxyanisole; Carcinogens; Clofibrate; Diethylnitrosamine; Ethionine; Glutathione Transferase; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Placenta; Precancerous Conditions; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Serum Albumin | 1993 |
Decreased connexin32 and a characteristic enzyme phenotype in clofibrate-induced preneoplastic lesions not shared with spontaneously occurring lesions in the rat liver.
Topics: Animals; Carcinogens; Clofibrate; Connexins; Diethylnitrosamine; gamma-Glutamyltransferase; Gap Junction beta-1 Protein; Glutathione Transferase; Liver Neoplasms, Experimental; Male; Microbodies; Phenotype; Precancerous Conditions; Rats; Rats, Wistar | 1996 |
Differential effects of nongenotoxic and genotoxic carcinogens on the preneoplastic lesions in the rat liver.
Topics: Administration, Oral; Animals; Body Weight; Carcinogens; Cell Count; Clofibrate; Diethylnitrosamine; Glutathione Transferase; Injections, Intraperitoneal; Liver Neoplasms; Male; Mutagens; Organ Size; Phenobarbital; Precancerous Conditions; Quinolines; Rats; Rats, Inbred F344 | 1998 |
The relationship between decrease in Cx32 and induction of P450 isozymes in the early phase of clofibrate hepatocarcinogenesis in the rat.
Topics: Animals; Body Weight; Carcinogenicity Tests; Carcinogens; Clofibrate; Connexins; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Disease Models, Animal; Drug Synergism; Enzyme Induction; Gap Junction beta-1 Protein; Glutathione Transferase; Hepatectomy; Hypertrophy; Immunoenzyme Techniques; Isoenzymes; Liver; Liver Neoplasms, Experimental; Male; Organ Size; Rats; Rats, Inbred F344 | 1999 |
alpha(2)-Macroglobulin: a novel cytochemical marker characterizing preneoplastic and neoplastic rat liver lesions negative for hitherto established cytochemical markers.
Topics: Adenoma; Alkylating Agents; alpha-Macroglobulins; Animals; Anticholesteremic Agents; Biomarkers, Tumor; Clofibrate; Diethylnitrosamine; Disease Progression; Gene Expression Regulation, Neoplastic; Glutathione Transferase; Immunohistochemistry; In Situ Hybridization; Lasers; Liver; Liver Neoplasms; Male; Oligonucleotide Array Sequence Analysis; Peroxisome Proliferators; Pyrimidines; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Time Factors; Up-Regulation | 2004 |
Comparison of mode of action of four hepatocarcinogens: a model-based approach.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Clofibrate; Diethylnitrosamine; Female; Liver Neoplasms; Male; Models, Biological; Nitrosamines; Phenobarbital; Rats; Rats, Wistar; Sex Characteristics; Substrate Specificity | 2007 |
Different induction of LPA receptors by chemical liver carcinogens regulates cellular functions of liver epithelial WB-F344 cells.
Topics: Animals; Carcinogens; Cell Line; Cell Movement; Clofibrate; Diethylnitrosamine; Epithelial Cells; Gene Expression Regulation; Liver Neoplasms, Experimental; Okadaic Acid; Phenobarbital; Rats; Rats, Inbred F344; Receptors, Lysophosphatidic Acid | 2016 |