clofibrate and colchicine

clofibrate has been researched along with colchicine in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19904 (22.22)18.7374
1990's0 (0.00)18.2507
2000's4 (22.22)29.6817
2010's10 (55.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Carew, TE; Steinberg, D; Weinstein, DB1
Crepaldi, G; Jemmolo, RM; Lirussi, F; Muraca, M; Nassuato, G; Okolicsanyi, L; Orlando, R; Strazzabosco, M1
Cain, GD; Rahman, F1
Gut, JP1
Akhurst, LC; Bertens, A; Botta, A; Cinelli, S; Clare, MG; Lorenzon, G; Lorge, E; Marzin, D; Montero, R; Thybaud, V; van Delft, J1
Araki, H; Hamada, S; Itoh, S; Kobayashi, K; Kubo, K; Lorenzon, G; Lorge, E; Marzin, D; Matsui, A; Matsuoka, A; Miyajima, H; Nishida, S; Senjyu, N; Thybaud, V; Wakata, A; Yamakage, K; Yamamura, E; Yoshida, J1
Aardema, MJ; Lorenzon, G; Lorge, E; Marzin, D; Oliver, J; Thybaud, V; Wakata, A1

Reviews

3 review(s) available for clofibrate and colchicine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The effect of drugs on bile flow and composition. An overview.
    Drugs, 1986, Volume: 31, Issue:5

    Topics: Animals; Bile; Bile Acids and Salts; Cats; Chlorpromazine; Cholagogues and Choleretics; Cholesterol; Clofibrate; Colchicine; Cricetinae; Dehydrocholic Acid; Diuretics; Dogs; Enterohepatic Circulation; Estrogens; Glucagon; Guinea Pigs; Humans; Insulin; Liver; Macaca mulatta; Phospholipids; Rabbits; Rats; Rifampin; Rifamycins; Somatostatin; Theophylline; Ursodeoxycholic Acid

1986
Current concepts in therapy: drug-induced malabsorption--a review.
    Southern medical journal, 1973, Volume: 66, Issue:6

    Topics: Aminosalicylic Acids; Calcium Carbonate; Cholestyramine Resin; Clofibrate; Colchicine; Contraceptives, Oral; Diuretics; Ethanol; Humans; Intestinal Absorption; Malabsorption Syndromes; Mannitol; Methotrexate; Phenytoin

1973

Other Studies

15 other study(ies) available for clofibrate and colchicine

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Pathogenesis of hyperlipidemias, clues to treatment?
    Advances in experimental medicine and biology, 1975, Volume: 63

    Topics: Animals; Cholesterol; Clofibrate; Colchicine; Hyperlipidemias; Lipoproteins; Lipoproteins, LDL; Muscle, Smooth; Portacaval Shunt, Surgical; Sterols; Swine

1975
[Changes in indications for drugs].
    La Revue du praticien, 1980, Feb-01, Volume: 30, Issue:7

    Topics: Amantadine; Clofibrate; Colchicine; Drug Therapy; Female; Gout; Humans; Levamisole; Metronidazole; Middle Aged; Probenecid; Sulfinpyrazone

1980
SFTG international collaborative study on in vitro micronucleus test II. Using human lymphocytes.
    Mutation research, 2006, Aug-04, Volume: 607, Issue:1

    Topics: Adult; Aneugens; Bleomycin; Clofibrate; Colchicine; Cytarabine; Diethylstilbestrol; Female; Fluorouracil; Humans; In Vitro Techniques; International Cooperation; Lymphocytes; Male; Mannitol; Micronucleus Tests; Mutagens; Thiabendazole; Urethane

2006
SFTG international collaborative study on in vitro micronucleus test IV. Using CHL cells.
    Mutation research, 2006, Aug-04, Volume: 607, Issue:1

    Topics: Aneugens; Animals; Bleomycin; Cell Line; Clofibrate; Colchicine; Cricetinae; Cytarabine; Cytochalasin B; Diethylstilbestrol; Fluorouracil; Griseofulvin; In Vitro Techniques; International Cooperation; Mannitol; Micronucleus Tests; Mutagens; Urethane

2006
SFTG international collaborative study on in vitro micronucleus test I. General conditions and overall conclusions of the study.
    Mutation research, 2006, Aug-04, Volume: 607, Issue:1

    Topics: Aneugens; Animals; Bleomycin; Cell Line; CHO Cells; Clofibrate; Colchicine; Cricetinae; Cytarabine; Cytochalasin B; Diethylstilbestrol; Fluorouracil; Griseofulvin; Humans; In Vitro Techniques; International Cooperation; Leukemia L5178; Lymphocytes; Mannitol; Mice; Micronucleus Tests; Mitomycin; Mutagens; Thiabendazole

2006