clofibrate and coenzyme a

clofibrate has been researched along with coenzyme a in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199025 (86.21)18.7374
1990's4 (13.79)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
De Duve, C; Lazarow, PB1
Lazarow, PB1
Gnoni, GV; Landriscina, C; Quagliariello, E1
Ball, MR; Gumaa, KA; McLean, P1
Halvorsen, O; Skrede, S1
Hassinen, IE; Jauhonen, VP; Savolainen, MJ; Voltti, H1
Brass, EP; Ruff, LJ1
Brass, EP1
Moore, KH; Solomon, FJ1
Balzer, I; Huth, W1
Agius, L; Bartlett, K; Bhuiyan, AK; Sherratt, HS1
Björkhem, I; Flatabø, T; Hvattum, E; Pedersen, JI1
Horie, S; Isobe, M; Suga, T1
Maragoudakis, ME1
Solberg, HE1
Adams, LL; Fallon, HJ; Lamb, RG1
Aas, M; Daae, LN; Solberg, HE1
Pettersen, JE1
Mishkin, S; Turcotte, R1
Fallon, HJ; Lamb, RG1
Galton, DJ; Wilson, JP1
White, LW1
Norseth, J1
Halvorsen, O1
Debeer, LJ; Mannaerts, GP1
Osmundsen, H1
Hassinen, IE; Voltti, H1
Sato, K; Sugiura, T; Tokudome, Y; Waku, K; Watanabe, M; Yamashita, A1
Chen, LS; Jin, SJ; Tserng, KY1

Reviews

1 review(s) available for clofibrate and coenzyme a

ArticleYear
A review of studies on the mode of action of clofibrate and betabenzalbutyrate.
    Lipids, 1972, Volume: 7, Issue:2

    Topics: Acyltransferases; Adenylyl Cyclase Inhibitors; Adipose Tissue; Albumins; Alkenes; Animals; Butyrates; Cholesterol; Clofibrate; Coenzyme A; Glycerol; Glycerophosphates; Ligases; Lipid Metabolism; Liver; Male; Microsomes, Liver; Protein Binding; Rats; Thyroxine; Triglycerides

1972

Other Studies

28 other study(ies) available for clofibrate and coenzyme a

ArticleYear
A fatty acyl-CoA oxidizing system in rat liver peroxisomes; enhancement by clofibrate, a hypolipidemic drug.
    Proceedings of the National Academy of Sciences of the United States of America, 1976, Volume: 73, Issue:6

    Topics: Animals; Clofibrate; Coenzyme A; Liver; Microbodies; NAD; Organoids; Oxidation-Reduction; Palmitates; Rats

1976
Three hypolipidemic drugs increase hepatic palmitoyl-coenzyme A oxidation in the rat.
    Science (New York, N.Y.), 1977, Aug-05, Volume: 197, Issue:4303

    Topics: Animals; Catalase; Clofibrate; Coenzyme A; Electron Transport Complex IV; Hypolipidemic Agents; Liver; Male; Microbodies; Organ Size; Oxidation-Reduction; Piperidines; Pyrimidines; Rats; Rats, Inbred F344; Xylenes

1977
On the mode of action of clofibrate on lipid metabolism. Inhibition of rat liver microsomal fatty acid synthesis.
    Biochemical medicine, 1975, Volume: 12, Issue:4

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Animals; Clofibrate; Coenzyme A; Fatty Acids; In Vitro Techniques; Liver; Male; Malonates; Microsomes, Liver; Rats; Subcellular Fractions

1975
Effect of clofibrate on the CoA thioester profile in rat liver.
    Biochemical and biophysical research communications, 1979, Mar-30, Volume: 87, Issue:2

    Topics: Acyl Coenzyme A; Animals; Citric Acid Cycle; Clofibrate; Coenzyme A; Dietary Fats; Energy Metabolism; Liver; Male; Mitochondrial ADP, ATP Translocases; Oxidation-Reduction; Rats

1979
Increased biosynthesis of CoA in the liver of rats treated with clofibrate.
    European journal of biochemistry, 1979, Volume: 98, Issue:1

    Topics: Acyl Coenzyme A; Animals; Clofibrate; Coenzyme A; Liver; Male; Pantothenic Acid; Rats; Subcellular Fractions

1979
Clofibrate-induced increase in coenzyme A concentration in rat tissues.
    The Biochemical journal, 1979, Jul-15, Volume: 182, Issue:1

    Topics: Animals; Chromatography, DEAE-Cellulose; Clofibrate; Coenzyme A; Kidney; Kinetics; Liver; Male; Muscles; Myocardium; Pantothenic Acid; Rats; Tissue Distribution

1979
Rat hepatic coenzyme A is redistributed in response to mitochondrial acyl-coenzyme A accumulation.
    The Journal of nutrition, 1992, Volume: 122, Issue:11

    Topics: Acyl Coenzyme A; Animals; Cell Nucleus; Cells, Cultured; Citrate (si)-Synthase; Clofibrate; Coenzyme A; Cytosol; Hydroxocobalamin; Liver; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley

1992
Interaction of carnitine and propionate with pyruvate oxidation by hepatocytes from clofibrate-treated rats: importance of coenzyme A availability.
    The Journal of nutrition, 1992, Volume: 122, Issue:2

    Topics: Animals; Carnitine; Carnitine O-Acetyltransferase; Cells, Cultured; Clofibrate; Coenzyme A; Liver; Male; Oxidation-Reduction; Propionates; Pyruvates; Rats; Rats, Inbred Strains

1992
Cardiac and hepatic acyl-CoA and acylcarnitine hydrolase activities in clofibrate-fed rabbits.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1985, Volume: 80, Issue:2

    Topics: Animals; Carboxylic Ester Hydrolases; Catalase; Clofibrate; Coenzyme A; Liver; Male; Microbodies; Myocardium; Palmitoyl-CoA Hydrolase; Rabbits; Thiolester Hydrolases

1985
Mitochondrial acetyl-CoA acetyltransferase in liver and extrahepatic tissues: role of modification by coenzyme A.
    Biochimica et biophysica acta, 1986, Mar-28, Volume: 870, Issue:2

    Topics: Acetyl-CoA C-Acetyltransferase; Acetyltransferases; Animals; Brain; Clofibrate; Coenzyme A; Diethylhexyl Phthalate; Immunoelectrophoresis; Ketone Bodies; Kidney; Kinetics; Male; Mitochondria; Mitochondria, Liver; Myocardium; Phthalic Acids; Rats; Rats, Inbred Strains

1986
Effects of ciprofibrate and 2-[5-(4-chlorophenyl)pentyl]oxirane-2-carboxylate (POCA) on the distribution of carnitine and CoA and their acyl-esters and on enzyme activities in rats. Relation between hepatic carnitine concentration and carnitine acetyltran
    The Biochemical journal, 1988, Jul-15, Volume: 253, Issue:2

    Topics: Acyl Coenzyme A; Animals; Carnitine; Carnitine O-Acetyltransferase; Cells, Cultured; Clofibrate; Clofibric Acid; Coenzyme A; Epoxy Compounds; Ethers, Cyclic; Fibric Acids; Hypoglycemic Agents; Hypolipidemic Agents; Liver; Male; Rats; Rats, Inbred Strains; Tissue Distribution

1988
Clofibrate does not induce peroxisomal 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestanoyl coenzyme A oxidation in rat liver. Evidence that this reaction is catalyzed by an enzyme system different from that of peroxisomal acyl-coenzyme A oxidation.
    Biochemistry international, 1988, Volume: 17, Issue:1

    Topics: Animals; Catalysis; Cholic Acids; Clofibrate; Coenzyme A; Liver; Male; Microbodies; Oxidation-Reduction; Oxidoreductases; Palmitic Acid; Palmitic Acids; Rats; Rats, Inbred Strains

1988
Changes in CoA pools in hepatic peroxisomes of the rat under various conditions.
    Journal of biochemistry, 1986, Volume: 99, Issue:5

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Centrifugation, Density Gradient; Clofibrate; Coenzyme A; Cytosol; Diabetes Mellitus, Experimental; Dietary Fats; Fasting; Liver; Male; Microbodies; Mitochondria, Liver; Rats; Rats, Inbred Strains

1986
On the mode of action of lipid-lowering agents. VI. Inhibition of lipogenesis in rat mammary gland cell culture.
    The Journal of biological chemistry, 1971, Jun-25, Volume: 246, Issue:12

    Topics: Acetates; Animals; Anticholesteremic Agents; Carbon Dioxide; Carbon Isotopes; Cell Line; Cell Membrane Permeability; Cholesterol; Chromatography; Chromatography, Thin Layer; Citrates; Clofibrate; Coenzyme A; Culture Techniques; Depression, Chemical; Fatty Acids, Nonesterified; Female; Glucose; Leucine; Ligases; Lipid Metabolism; Lipids; Magnesium; Malonates; Mammary Glands, Animal; Mevalonic Acid; Naphthalenes; Palmitic Acids; Phenols; Propionates; Rats; Silicon Dioxide

1971
Acyl group specificity of mitochondrial pools of carnitine acyltransferases.
    Biochimica et biophysica acta, 1974, Aug-22, Volume: 360, Issue:2

    Topics: Acyltransferases; Animals; Carnitine; Cattle; Clofibrate; Coenzyme A; Digitonin; Fatty Acids; Female; Liver; Male; Membranes; Mice; Mitochondria, Liver; Oxidation-Reduction; Rats; Sulfates; Tritium

1974
The activity of the different carnitine acyltransferases in the liver of clofibrate-fed rats.
    Biochimica et biophysica acta, 1972, Nov-30, Volume: 280, Issue:3

    Topics: Acyltransferases; Animals; Carnitine; Clofibrate; Coenzyme A; Kinetics; Liver; Male; Organ Size; Proteins; Rats; Thiolester Hydrolases; Tritium

1972
In vitro studies on the metabolism of hexadecanedioic acid and its mono-L-carnitine ester.
    Biochimica et biophysica acta, 1973, Apr-13, Volume: 306, Issue:1

    Topics: Acyltransferases; Animals; Carnitine; Clofibrate; Coenzyme A; Diabetes Mellitus; Esters; Fasting; Male; Mass Spectrometry; Mitochondria, Liver; Mitochondria, Muscle; Palmitic Acids; Rats; Tritium

1973
The binding of long chain fatty acid CoA to Z, a cytoplasmic protein present in liver and other tissues of the rat.
    Biochemical and biophysical research communications, 1974, Apr-08, Volume: 57, Issue:3

    Topics: Animals; Binding Sites; Carbon Radioisotopes; Carrier Proteins; Chromatography, Gel; Clofibrate; Coenzyme A; Fatty Acids; Kinetics; Liver; Male; Organ Specificity; Palmitic Acids; Protein Binding; Rats; Receptors, Drug; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Tritium; Ultracentrifugation

1974
Inhibition of monoacylglycerophosphate formation by chlorophenoxyisobutyrate and -benzalbutyrate.
    The Journal of biological chemistry, 1972, Feb-25, Volume: 247, Issue:4

    Topics: Acylation; Acyltransferases; Albumins; Alkenes; Animals; Butyrates; Carbon Isotopes; Clofibrate; Coenzyme A; Glycerides; Glycerophosphates; Hypolipidemic Agents; Metabolism; Microsomes, Liver; Palmitic Acids; Phospholipids; Protein Binding; Rats; Triglycerides

1972
The effect of drugs on lipogenesis from glucose and palmitate in human adipose tissue.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1971, Volume: 3, Issue:4

    Topics: Acetazolamide; Acylation; Adipose Tissue; Benzoates; Carbon Isotopes; Clofibrate; Coenzyme A; Depression, Chemical; Ethacrynic Acid; Fatty Acids; Fenfluramine; Glucose; Glycerophosphates; Humans; In Vitro Techniques; Lipids; Metabolism; Palmitic Acids; Peritoneal Cavity; Phenethylamines; Skin; Structure-Activity Relationship; Subcellular Fractions; Time Factors; Tritium

1971
Regulation of hepatic cholesterol biosynthesis by clofibrate administration.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 178, Issue:2

    Topics: Acetates; Acetoacetates; Alcohol Oxidoreductases; Animals; Anticholesteremic Agents; Carbon Dioxide; Carbon Isotopes; Cholesterol; Clofibrate; Coenzyme A; Depression, Chemical; Fatty Acids; In Vitro Techniques; Liver; Male; Mevalonic Acid; Propionates; Pyruvates; Rats

1971
Increased beta-oxidation of erucic acid in perfused hearts from rats fed clofibrate.
    Biochimica et biophysica acta, 1980, Feb-22, Volume: 617, Issue:2

    Topics: Animals; Catalase; Clofibrate; Coenzyme A; Electron Transport Complex IV; Erucic Acids; Fatty Acids; Fatty Acids, Unsaturated; Heart; In Vitro Techniques; Male; Myocardium; Oxidation-Reduction; Palmitic Acids; Perfusion; Rats

1980
Effects of hypolipidemic drugs on hepatic CoA.
    Biochemical pharmacology, 1983, Mar-15, Volume: 32, Issue:6

    Topics: Animals; Clofibrate; Coenzyme A; Hypolipidemic Agents; Lipids; Liver; Male; Organ Size; Rats; Rats, Inbred Strains

1983
Mitochondrial and peroxisomal beta-oxidation of fatty acids in rat liver.
    Annals of the New York Academy of Sciences, 1982, Volume: 386

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Clofibrate; Coenzyme A; Fatty Acids; Kinetics; Liver; Microbodies; Mitochondria, Liver; NAD; Oleic Acid; Oleic Acids; Organoids; Oxidation-Reduction; Palmitic Acid; Palmitic Acids; Rats

1982
Factors which can influence beta-oxidation by peroxisomes isolated from livers of clofibrate treated rats. Some properties of peroxisomal fractions isolated in a self-generated Percoll gradient by vertical rotor centrifugation.
    The International journal of biochemistry, 1982, Volume: 14, Issue:10

    Topics: Animals; Centrifugation, Density Gradient; Chemical Phenomena; Chemistry; Clofibrate; Coenzyme A; Liver; Male; Microbodies; NAD; Organoids; Oxidation-Reduction; Rats; Rats, Inbred Strains

1982
A subcellular study of the clofibrate-induced increase in coenzyme A concentration in rat liver.
    Biochemical pharmacology, 1980, Apr-01, Volume: 29, Issue:7

    Topics: Animals; Clofibrate; Coenzyme A; Cytochromes; Cytosol; Glutamate Dehydrogenase; Liver; Male; Mitochondria, Liver; Pantothenic Acid; Rats; Subcellular Fractions

1980
Induction of coenzyme A-dependent transacylation activity in rat liver microsomes by administration of clofibrate.
    Biochimica et biophysica acta, 1994, Mar-24, Volume: 1211, Issue:3

    Topics: Acyltransferases; Animals; Clofibrate; Coenzyme A; Enzyme Induction; Male; Microsomes, Liver; Phospholipids; Rats; Rats, Wistar

1994
Reduction pathway of cis-5 unsaturated fatty acids in intact rat-liver and rat-heart mitochondria: assessment with stable-isotype-labelled substrates.
    The Biochemical journal, 1996, Jan-15, Volume: 313 ( Pt 2)

    Topics: Animals; Carbon Isotopes; Carnitine; Clofibrate; Coenzyme A; Dietary Fats; Dinitrophenols; Fasting; Fatty Acids, Unsaturated; Gas Chromatography-Mass Spectrometry; Male; Mitochondria, Heart; Mitochondria, Liver; Oxidation-Reduction; Rats; Rats, Sprague-Dawley

1996