clofibrate and bilirubin

clofibrate has been researched along with bilirubin in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199016 (45.71)18.7374
1990's5 (14.29)18.2507
2000's8 (22.86)29.6817
2010's6 (17.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Glen, RC; Lowe, R; Mitchell, JB1
Fent, K; Popovic, M; Smital, T; Zaja, R1
Celier, C; Etienne, JP; Foliot, A; Housset, E; Jean, F1
Azarnoff, DL; Dujovne, CA; Huffman, DH; Hurwitz, A; Pentikäinen, P; Shoeman, DW1
Christoforov, B; Drocourt, JL; Etienne, JP; Fiessinger, JN; Foliot, A; Housset, E1
Tangedahl, TN1
Levy, VG; Noel, P; Nusinovici, V1
Burchell, B; Clarke, DJ; George, SG1
Dragacci, S; Fournel-Gigleux, S; Hamar-Hansen, C; Lafaurie, C; Magdalou, J; Siest, G1
Benattar, C; Dehan, M; Delaporte, B; Gabilan, JC; Gerbet, D; Leluc, R; Lindenbaum, A; Magny, JF1
Burchell, B; Celier, C; Scragg, I1
André, JC; Caldwell, J; Fournel, S; Magdalou, J; Siest, G; Thomassin, J; Villoutreix, J1
Debray, C; Rozé, C; Souchard, M; Vaille, C1
Cremonini, R; Dal Monte, PR; Menghi, B; Sarti, F; Toscano, S1
Celier, C; Foliot, A1
Barré, J; Benattar, C; Houin, G; Lindenbaum, A; Shastri, RA; Tillement, JP1
Fevery, J; Gugler, R; Kandler, H; Kutz, K1
Seidel, D; Walli, AK1
May, B; Müller, KM; Schwegler, U1
Maynard, A; Miller, M; Wennberg, RP; Yin, J1
Emi, Y; Ikushiro, S; Iyanagi, T1
Crippin, JS; Gores, GJ; Gossard, A; Laurin, J; Lindor, KD; Ludwig, J; McGill, DB; Rakela, J1
Jemnitz, K; Lengyel, G; Vereczkey, L1
Dennery, PA1
Farhat, ASh; Iranpour, R; Mohammadzadeh, A1
Ahmadpour-Kacho, M; Hajiahmadi, M; Naderi, S; Zahedpasha, Y1
Eghbalian, F; Pourhossein, A; Zandevakili, H1
Ahmadpour-Kacho, M; Hajiahmadi, M; Kamali, AA; Naderi, S; Zahedpasha, Y1
Gharehbaghi, MM; Rahbani, ME; Sakha, SH1
Ahmadabadi, F; Ayazi, P; Habibi, M; Javadi, A; Mahyar, A1
Chen, D; Duan, Z; Mu, D; Qu, Y; Xiong, T1
Saburi, A; Torkaman, M1
Bánfai, B; Bennecke, M; Christen, F; Festag, M; Lenz, B; Maliver, P; Winter, M1

Reviews

3 review(s) available for clofibrate and bilirubin

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
Pharmacological interventions for the treatment of neonatal jaundice.
    Seminars in neonatology : SN, 2002, Volume: 7, Issue:2

    Topics: Agar; Bilirubin; Charcoal; Clofibrate; Drugs, Chinese Herbal; Heme; Humans; Infant, Newborn; Jaundice, Neonatal; Liver Circulation; Metalloporphyrins; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Penicillamine; Phenobarbital; Treatment Outcome

2002
Clofibrate for unconjugated hyperbilirubinemia in neonates: a systematic review.
    Indian pediatrics, 2012, Volume: 49, Issue:1

    Topics: Bilirubin; Clofibrate; Humans; Hyperbilirubinemia, Neonatal; Infant, Newborn; Phototherapy; Treatment Outcome

2012

Trials

10 trial(s) available for clofibrate and bilirubin

ArticleYear
One-year trials with halofenate, clofibrate, and placebo.
    Clinical pharmacology and therapeutics, 1976, Volume: 19, Issue:3

    Topics: Adult; Aged; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Cholesterol; Clinical Trials as Topic; Clofibrate; Creatine Kinase; Female; Glycolates; Halofenate; Humans; Hyperlipidemias; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Middle Aged; Triglycerides; Uric Acid

1976
[Preventive treatment of jaundice in premature newborn infants with clofibrate. Double-blind controlled therapeutic trial].
    Archives francaises de pediatrie, 1985, Volume: 42, Issue:9

    Topics: Bilirubin; Clinical Trials as Topic; Clofibrate; Double-Blind Method; Female; Gestational Age; Humans; Infant, Newborn; Infant, Premature, Diseases; Jaundice, Neonatal; Male; Phototherapy; Time Factors

1985
The coronary drug project. Design, methods, and baseline results.
    Circulation, 1973, Volume: 47, Issue:3 Suppl

    Topics: Adult; Alkaline Phosphatase; Anticholesteremic Agents; Bilirubin; Blood Glucose; Blood Pressure; Blood Urea Nitrogen; Cholesterol; Clinical Trials as Topic; Clofibrate; Coronary Disease; Dextrothyroxine; Electrocardiography; Estrogens; Humans; Male; Methods; Middle Aged; Myocardial Infarction; Nicotinic Acids; Placebos; Research Design; Smoking; Triglycerides; United States; Uric Acid

1973
Fetal cocaine exposure and neonatal bilirubinemia.
    The Journal of pediatrics, 1994, Volume: 125, Issue:4

    Topics: Animals; Bilirubin; Case-Control Studies; Clofibrate; Cocaine; Female; Humans; Infant, Newborn; Liver; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley

1994
Effect of clofibrate in jaundiced term newborns.
    Indian journal of pediatrics, 2005, Volume: 72, Issue:2

    Topics: Bilirubin; Clofibrate; Combined Modality Therapy; Female; Humans; Infant, Newborn; Jaundice, Neonatal; Male; Phototherapy; Prospective Studies

2005
Effect of clofibrate in jaundiced full-term infants:a randomized clinical trial.
    Archives of Iranian medicine, 2007, Volume: 10, Issue:3

    Topics: Administration, Oral; Bilirubin; Clofibrate; Combined Modality Therapy; Female; Humans; Hypolipidemic Agents; Infant, Newborn; Jaundice, Neonatal; Length of Stay; Male; Phototherapy; Treatment Outcome

2007
Effect of clofibrate in non-hemolytic indirect hyperbiliru-binemia in full term neonates.
    Indian journal of pediatrics, 2007, Volume: 74, Issue:11

    Topics: Anticholesteremic Agents; Bilirubin; Clofibrate; Combined Modality Therapy; Female; Humans; Hyperbilirubinemia, Neonatal; Infant, Newborn; Male; Phototherapy

2007
Efficacy of clofibrate on severe neonatal jaundice associated with glucose-6-phosphate dehydrogenase deficiency (a randomized clinical trial).
    The Southeast Asian journal of tropical medicine and public health, 2008, Volume: 39, Issue:3

    Topics: Bilirubin; Clofibrate; Combined Modality Therapy; Female; Glucosephosphate Dehydrogenase Deficiency; Humans; Hypolipidemic Agents; Infant, Newborn; Jaundice, Neonatal; Male; Phototherapy; Treatment Outcome

2008
The effect of clofibrate with phototherapy in late pre-term newborns with non-hemolytic jaundice.
    Indian journal of medical sciences, 2009, Volume: 63, Issue:5

    Topics: Bilirubin; Clofibrate; Combined Modality Therapy; Double-Blind Method; Female; Humans; Hyperbilirubinemia, Neonatal; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Jaundice, Neonatal; Male; Phototherapy

2009
The effect of clofibrate on hyperbilirubinemia of term neonates.
    Acta medica Iranica, 2012, Volume: 50, Issue:1

    Topics: Bilirubin; Biomarkers; Clofibrate; Combined Modality Therapy; Female; Humans; Hyperbilirubinemia, Neonatal; Infant, Newborn; Iran; Male; Phototherapy; Single-Blind Method; Time Factors; Treatment Outcome

2012

Other Studies

22 other study(ies) available for clofibrate and bilirubin

ArticleYear
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Molecular characterization of zebrafish Oatp1d1 (Slco1d1), a novel organic anion-transporting polypeptide.
    The Journal of biological chemistry, 2013, Nov-22, Volume: 288, Issue:47

    Topics: Animals; Evolution, Molecular; Glycosylation; Gonadal Steroid Hormones; HEK293 Cells; Humans; Ion Transport; Organic Anion Transporters; Protein Multimerization; Zebrafish; Zebrafish Proteins

2013
Influence of clofibrate on hepatic transport of bilirubin and bromosulfophthalein in rats.
    Biochemical and biophysical research communications, 1979, Feb-28, Volume: 86, Issue:4

    Topics: Animals; Bile; Bilirubin; Biological Transport; Clofibrate; Glucuronosyltransferase; Liver; Male; Rats; Sulfobromophthalein

1979
Increase in the hepatic glucuronidation and clearance of bilirubin in clofibrate-treated rats.
    Biochemical pharmacology, 1977, Mar-15, Volume: 26, Issue:6

    Topics: Animals; Bilirubin; Binding Sites; Clofibrate; Dose-Response Relationship, Drug; Glucuronates; Glucuronosyltransferase; Kinetics; Liver; Male; Organ Size; Rats; Sulfobromophthalein

1977
Who gets gallstones and why.
    Postgraduate medicine, 1979, Volume: 66, Issue:3

    Topics: Bilirubin; Cholelithiasis; Cholesterol; Clofibrate; Estrogens; Hemolysis; Indians, North American; Obesity; Risk

1979
[Enzyme induction and intrahepatic cholestasis].
    Medecine & chirurgie digestives, 1978, Volume: 7, Issue:2

    Topics: Bilirubin; Cholestasis; Clofibrate; Coenzyme A Ligases; Enzyme Induction; Glucuronates; Glutethimide; Hexosyltransferases; Humans; Phenobarbital

1978
Differential expression and induction of UDP-glucuronosyltransferase isoforms in hepatic and extrahepatic tissues of a fish, Pleuronectes platessa: immunochemical and functional characterization.
    Toxicology and applied pharmacology, 1992, Volume: 115, Issue:1

    Topics: Animals; Aroclors; Bilirubin; Blotting, Western; Chlorodiphenyl (54% Chlorine); Clofibrate; Corn Oil; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Flounder; Glucuronosyltransferase; Immunohistochemistry; Intestines; Isoenzymes; Kidney; Liver; Methylcholanthrene; Microsomes; Naphthols; Testosterone; Tissue Distribution

1992
Comparative study of clofibric acid and bilirubin glucuronidation in human liver microsomes.
    Biochemical pharmacology, 1987, Nov-15, Volume: 36, Issue:22

    Topics: Adult; Age Factors; Aged; Alcohol Drinking; Animals; Bilirubin; Clofibrate; Clofibric Acid; Female; Glucuronosyltransferase; Humans; Kinetics; Male; Microsomes, Liver; Middle Aged; Rats; Reference Values; Sex Factors; Smoking

1987
Congenital jaundice in rats due to the absence of hepatic bilirubin UDP-glucuronyltransferase enzyme protein.
    FEBS letters, 1985, Apr-08, Volume: 183, Issue:1

    Topics: Animals; Bilirubin; Clofibrate; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Glucuronosyltransferase; Immunoassay; Isoenzymes; Jaundice; Liver; Male; Microsomes, Liver; Phenol; Phenols; Rats; Rats, Gunn; Rats, Inbred Strains

1985
Structure-dependent induction of bilirubin glucuronidation and lauric acid 12-hydroxylation by arylcarboxylic acids chemically related to clofibrate.
    Biochimica et biophysica acta, 1985, Oct-17, Volume: 842, Issue:2-3

    Topics: Animals; Bilirubin; Clofibrate; Cytochrome P-450 Enzyme System; Enzyme Induction; Glucuronates; Glucuronosyltransferase; Hydroxylation; Kinetics; Lauric Acids; Male; Microsomes, Liver; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Thermodynamics

1985
[Induced hypercholeresis and excretion of bile salts after treatment with clofibrate].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1972, Jun-19, Volume: 274, Issue:25

    Topics: Animals; Bicarbonates; Bile; Bile Acids and Salts; Bilirubin; Chlorine; Clofibrate; Hepatomegaly; Liver; Male; Potassium; Rats; Sodium

1972
[Study of hepatic function before and after administration of therapeutic doses of clofibrate].
    Minerva medica, 1971, Dec-22, Volume: 62, Issue:97

    Topics: Adult; Aged; Alkaline Phosphatase; Arteriosclerosis; Bilirubin; Clofibrate; Female; Humans; Hypercholesterolemia; Liver; Liver Function Tests; Male; Middle Aged; Transaminases

1971
Bilirubin content and 4-nitrophenol glucuronosyltransferase activity in Gunn rat liver.
    Clinical science (London, England : 1979), 1984, Volume: 66, Issue:4

    Topics: Animals; Bilirubin; Clofibrate; Dietary Fats; Glucuronosyltransferase; Hyperbilirubinemia, Hereditary; Liver; Male; Proteins; Rats; Rats, Gunn

1984
Effect of hyperbilirubinaemia on the plasma protein binding of chlorophenoxyisobutyric acid in neonates.
    Developmental pharmacology and therapeutics, 1984, Volume: 7 Suppl 1

    Topics: Bilirubin; Blood Proteins; Clofibrate; Clofibric Acid; Humans; Infant, Newborn; Jaundice, Neonatal; Kinetics

1984
Effect of clofibrate on the metabolism of bilirubin, bromosulphophthalein and indocyanine green and on the biliary lipid composition in Gilbert's syndrome.
    Clinical science (London, England : 1979), 1984, Volume: 66, Issue:4

    Topics: Adult; Bile; Bilirubin; Clofibrate; Female; Gilbert Disease; Humans; Hyperbilirubinemia, Hereditary; Indocyanine Green; Lipid Metabolism; Liver; Male; Sulfobromophthalein

1984
Effects of clofibric acid and bezafibrate administration on activities of alkaline phosphatase and other enzymes in livers of rats.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1981, Volume: 179, Issue:2

    Topics: Alkaline Phosphatase; Animals; Bezafibrate; Bilirubin; Clofibrate; Clofibric Acid; Glucuronates; Glucuronosyltransferase; Hexosyltransferases; Hypolipidemic Agents; Liver; Male; Microsomes, Liver; Rats; Rats, Inbred Strains

1981
[Crigler-Najjar syndrome type II in a 17-year-old girl].
    Zeitschrift fur Gastroenterologie, 1993, Volume: 31 Suppl 2

    Topics: Adolescent; Bilirubin; Biopsy; Chromosome Aberrations; Chromosome Disorders; Clofibrate; Crigler-Najjar Syndrome; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Genes, Dominant; Glucuronosyltransferase; Humans; Liver; Liver Function Tests

1993
Identification and analysis of drug-responsive expression of UDP-glucuronosyltransferase family 1 (UGT1) isozyme in rat hepatic microsomes using anti-peptide antibodies.
    Archives of biochemistry and biophysics, 1995, Dec-20, Volume: 324, Issue:2

    Topics: Amino Acid Sequence; Animals; Antibody Specificity; Bilirubin; Clofibrate; Dexamethasone; Enzyme Induction; Glucuronosyltransferase; Isoenzymes; Male; Microsomes, Liver; Molecular Sequence Data; Nitrophenols; Oligopeptides; Peptide Fragments; Pharmacology; Rats; Rats, Gunn; Rats, Wistar

1995
Ursodeoxycholic acid or clofibrate in the treatment of non-alcohol-induced steatohepatitis: a pilot study.
    Hepatology (Baltimore, Md.), 1996, Volume: 23, Issue:6

    Topics: Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Clofibrate; Drug Evaluation; Fatty Liver; Female; gamma-Glutamyltransferase; Gastrointestinal Agents; Hepatitis; Humans; Hypolipidemic Agents; Male; Middle Aged; Pilot Projects; Ursodeoxycholic Acid

1996
In vitro induction of bilirubin conjugation in primary rat hepatocyte culture.
    Biochemical and biophysical research communications, 2002, Feb-15, Volume: 291, Issue:1

    Topics: Animals; Bilirubin; Cells, Cultured; Clofibrate; Dexamethasone; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; Glucocorticoids; Glucuronosyltransferase; Hepatocytes; Hypolipidemic Agents; Immunoblotting; Isoenzymes; Male; Methylcholanthrene; Rats; Rats, Wistar; Rifampin

2002
What is important about the effect of clofibrate on neonatal hyperbilirubinemia?
    Acta medica Iranica, 2013, Mar-16, Volume: 51, Issue:2

    Topics: Bilirubin; Clofibrate; Female; Humans; Hyperbilirubinemia, Neonatal; Male; Phototherapy

2013
Assessment of Preclinical Liver and Skeletal Muscle Biomarkers Following Clofibrate Administration in Wistar Rats.
    Toxicologic pathology, 2017, Volume: 45, Issue:4

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Anticholesteremic Agents; Arginase; Aspartate Aminotransferases; Bilirubin; Biomarkers; Chemical and Drug Induced Liver Injury; Cholesterol; Cholinesterases; Clofibrate; Creatinine; Dose-Response Relationship, Drug; Fatty Acid Binding Protein 3; Glutamate Dehydrogenase; Keratin-18; Liver; Male; MicroRNAs; Muscle, Skeletal; Myosin Light Chains; Rats; Rats, Wistar; Triglycerides

2017