clofibrate and bezafibrate

clofibrate has been researched along with bezafibrate in 126 studies

Research

Studies (126)

TimeframeStudies, this research(%)All Research%
pre-199070 (55.56)18.7374
1990's35 (27.78)18.2507
2000's13 (10.32)29.6817
2010's7 (5.56)24.3611
2020's1 (0.79)2.80

Authors

AuthorsStudies
Brown, PJ; Henke, BR; Sternbach, DD; Willson, TM1
Henke, BR1
Chuang, S; Horne, J; Porter, CJ; Scanlon, MJ; Velkov, T1
Abuo-Rahma, Gel-D; Aly, OM; Idrees, GA; Radwan, MF1
Chalmers, DK; Chuang, S; Horne, J; Porter, CJ; Scanlon, MJ; Velkov, T; Wielens, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Fent, K; Popovic, M; Smital, T; Zaja, R1
Bolzano, K; Krempler, F; Schellenberg, B; Schlierf, G1
Imanaka, T; Itoga, H; Okawa, S; Suga, T; Watanabe, T1
Dorić, M; Gligora, M1
Iida, T; Suga, T; Tamura, H; Watanabe, T2
Eacho, PI; Foxworthy, PS; Hoover, DM; White, SL1
Schwandt, P1
Kłosiewicz-Latoszek, L; Szostak, WB1
Hirst, DG1
Bass, NM; Brandes, R; Kaikaus, RM; Lysenko, N; Ockner, RK1
Abraham, DJ; Mehanna, AS1
Hirst, DG; Wood, PJ1
Green, KG; Heady, A; Oliver, MF1
Angelin, B; Einarsson, K; Ståhlberg, D1
Arad, R; Bar-Tana, J; Brandes, R1
Agius, L; Alberti, KG; Gerondaes, P2
Krause, BR; Newton, RS1
Bonner, FW; Eason, CT; Howells, DD; Pattison, A; Spencer, AJ1
Palmer, RH1
Hunninghake, DB; Peters, JR1
Grundy, SM; Vega, GL1
Kurasawa, T; Yamamoto, A; Yokoyama, S1
Hirst, DG; Schwartz, HC; Wood, PJ1
Postiglione, A; Riccardi, G; Saldalamacchia, G1
Branzoli, U; Carganico, G; Chiari, A; Cozzi, P; Lovisolo, PP; Severino, D1
Lang, PD; Oster, P; Schlierf, G; Vollmar, J1
Lang, PD; Mordasini, R; Oster, P; Schlierf, G; Vollmar, J1
Perutz, MF; Poyart, C1
Boag, DE; Lorimer, AR; Packard, CJ; Shepherd, J; Stewart, JM1
Honková, M; Kunesová, M; Mares, P; Skorepa, J; Zeman, M1
Maxwell, RE; Nawrocki, JW; Uhlendorf, PD1
Harvengt, C; Heller, F1
Rüth, E; Vollmar, J1
Fischer, H; Oster, P; Roche, A; Schellenberg, B; Schlierf, G; Stiehl, A; Vollmar, J1
Keller, M; Lang, PD; Middelhoff, G; Mordasini, R; Oster, P; Riesen, W1
Holler, HD; Janka, HU; Mehnert, H; Standl, A1
Dorda, W; Kostner, GM; Mühlhauser, I; Prager, R; Schernthaner, G; Zechner, R1
Lang, PD; Vollmar, J1
Day, AJ; Hudson, K; Mojumder, S1
Kurlat, MI; Neuman, J; Neuman, MP1
Djaja, S; Machalke, K; Richter, E1
Fahimi, HD; Hartig, F; Ozel, M; Reinicke, A; Stegmeier, K; Sujatta, M; Yokota, S1
Lageder, H1
Abshagen, U; Marinow, J; Spörl-Radun, S1
Boberg, J; Gustafsson, IB; Hellsing, K; Ledermann, H; Lithell, H; Ostlund-Lindqvist, AM; Vessby, B1
Kokot, F; Szczechowska, E1
Dick, TB; Ledermann, HM; Marples, J; Whittington, J1
Grützmacher, P; Lang, W; Scheuermann, E1
Day, AJ; Hudson, K; Marceglia, A1
Bode, G; Ditschuneit, H; Hutt, V; Klör, HU; Wechsler, JG1
Drosner, M; Janetschek, P; Schwandt, P; Weisweiler, P1
Lazarow, PB; Leroy-Houyet, MA; Shio, H1
Lang, PD; Mertz, DP; Vollmar, J1
Lehmann-Leo, W; Luley, C; Scheffler, W; Schilling, A; Schwartzkopff, W; Wegscheider, K1
Ledermann, H; Lithell, H; Vessby, B1
Heidland, A; Hörl, M; Hörl, WH1
Anderson, P; Norbeck, HE2
Fringes, B; Riede, UN; von Deimling, O1
Day, AJ; Hudson, K1
Braeuning, C; Middelhoff, G; Schlierf, G; Wirth, A1
Kłosiewicz-Latoszek, L; Naruszewicz, M; Nowicka, G; Szostak, WB1
Hofmann, H; Holler, HD; Stratmann, FW1
Bertuletti, R; Carini, M; Maffei, FR; Tofanetti, O1
Schwandt, P; Weisweiler, P1
Ditschuneit, H; Hutt, V; Klör, HU; Wechsler, JG2
Hausmann, L; Kaffarnik, H; Mühlfellner, G; Mühlfellner, O; Schneider, J; Schubotz, R1
Seidel, D; Walli, AK1
Bock, KD; Heidemann, H1
Kjellin, KG; Ledermann, H; Noring, L1
Bruneder, H; Klein, HJ1
Bock, KD1
Kaufmann, B; Ledermann, H1
Carini, M; Facino, RM1
Abshagen, U; Kaufmann, B; Kösters, W; Lang, PD1
Bachmann, C; Fragiacomo, C; Noseda, G; Weidmann, P1
Calder, D; Luley, C; Scheffler, W; Schilling, A; Schwartzkopff, W1
Mertz, DP1
Adzet, T; Alegret, M; Cerqueda, E; Ferrando, R; Laguna, JC; Merlos, M; Sánchez, RM; Vázquez, M1
Shand, JH; West, DW3
Dujovne, CA; Lozada, A1
Gibson, GG; Howes, D; Kass, GE; Orrenius, S; Shackleton, GL; Sharma, RK1
Adzet, T; Alegret, M; Ferrando, R; Laguna, JC; Merlos, M; Vázquez, M1
Betteridge, L; Chan, P; Gallagher, K; Munro, E; Patel, M; Schachter, M; Sever, P; Wolfe, J1
Kato, N; Sasago, S; Satoh, A; Takahashi, S1
Amiconi, G; Ascenzi, P; Bertollini, A; Coletta, M; Desideri, A; Giardina, B; Polizio, F; Santucci, R; Scatena, R1
Bismuth, J; Bonne, J; Gharbi-Chihi, J; Teboul, M; Torresani, J1
Accatino, L; Amigo, L; Andrade, L; Chianale, J; Gonzalez, S; Nervi, F; Pizarro, M; Rigotti, A; Vollrath, V; Wielandt, AM1
Adzet, T; Alegret, M; Laguna, JC; Merlos, M; Muñoz, S; Vázquez, M1
Adzet, T; Alegret, M; Laguna, JC; López, M; Merlos, M; Rodríguez, C; Vázquez, M1
Galloway, SM; Johnson, TE; Ledwith, BJ; Manam, S; Nichols, WW; Pauley, CJ; Wagner, LK1
Auerbach, BJ; Barnett, BC; DeMattos, RB; Essenburg, AD; Haubenwallner, S; Krause, BR; Leff, T; Minton, LL; Newton, RS; Pape, ME1
Adzet, T; Laguna, JC; Merlos, M; Vázquez, M1
Diemer, S; Eberlein-König, B; Przybilla, B1
Amacher, DE; Beck, R; Kenny, CV; Schomaker, SJ1
Andersen, O; Dehli, A; Gjøen, T; Ostlund Farrants, AK; Ruyter, B; Thomassen, MS1
de Wit, EC; Huisman, H; Kaptein, A; Neele, DM; Princen, HM1
Wallace, KB; Zhou, S1
Brun, S; Carmona, MC; Giralt, M; Iglesias, R; Mampel, T; Villarroya, F; Viñas, O1
Arakawa, M; Hasegawa, H; Ishikawa, H; Ito, S; Murasawa, A; Nakano, M; Nakazono, K; Nozawa, S; Onuki, K; Tohyama, C1
Tada, N1
Ascenzi, P; Coletta, M; Fasano, M; Mattu, M; Vannin, A1
Fujisaki, K; Itoh, Y; Maiguma, T; Makino, K; Oishi, R; Sasaguri, T; Takahashi-Yanaga, F; Teshima, D1
Agellon, LB; Gbaguidi, GF1
Dobordzhginidze, LM; Gratsianskiĭ, NA1
Baldwin, GS; Ford, J; Lachal, S; Shulkes, A1
Chinetti, G; Fontaine, C; Fruchart, JC; Robillard, R; Staels, B1
Dellavalle, RP; Drake, AL; Freeman, SR; Graber, M; Heilig, LF; McNealy, K; Schilling, LM1
Abe, S; Hattori, H; Ishizawa, K; Kamiya, M; Kawamura, T; Matsumura, K; Matsushita, T; Miyamoto, L; Nakamoto, A; Nemoto, H; Taoka, C; Tsuchiya, K1
Hao, Z; Liu, B; Liu, M; Tao, W; Wang, D1
Jiao, S; Li, Q; Pan, M; Qu, J; Reinach, PS; Srinivasalu, N; Yan, J; Yang, Y; Zhou, X1
de Haas, R; Frambach, SJCM; Russel, FGM; Schirris, TJJ; Smeitink, JAM; van de Wal, MAE; van den Broek, PHH1

Reviews

11 review(s) available for clofibrate and bezafibrate

ArticleYear
The PPARs: from orphan receptors to drug discovery.
    Journal of medicinal chemistry, 2000, Feb-24, Volume: 43, Issue:4

    Topics: Animals; Diabetes Mellitus; Drug Design; Humans; Hyperlipidemias; Hypertension; Inflammation; Ligands; Models, Molecular; Neoplasms; Nuclear Proteins; Obesity; Receptors, Cytoplasmic and Nuclear; Transcription Factors

2000
Peroxisome proliferator-activated receptor alpha/gamma dual agonists for the treatment of type 2 diabetes.
    Journal of medicinal chemistry, 2004, Aug-12, Volume: 47, Issue:17

    Topics: Animals; Diabetes Mellitus, Type 2; Humans; Hyperglycemia; Hypoglycemic Agents; Models, Molecular; Molecular Structure; Receptors, Cytoplasmic and Nuclear; Transcription Factors

2004
Effects of fibric acid derivatives on biliary lipid composition.
    The American journal of medicine, 1987, Nov-27, Volume: 83, Issue:5B

    Topics: Bezafibrate; Clinical Trials as Topic; Clofibrate; Clofibric Acid; Double-Blind Method; Female; Fenofibrate; Fibric Acids; Humans; Hyperlipoproteinemia Type II; Hypolipidemic Agents; Male; Propionates; Random Allocation

1987
Effect of fibric acid derivatives on blood lipid and lipoprotein levels.
    The American journal of medicine, 1987, Nov-27, Volume: 83, Issue:5B

    Topics: Anticholesteremic Agents; Bezafibrate; Clofibrate; Clofibric Acid; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hyperlipoproteinemia Type II; Lipids; Lipoproteins; Pentanoic Acids

1987
Fibric acids: effects on lipids and lipoprotein metabolism.
    The American journal of medicine, 1987, Nov-27, Volume: 83, Issue:5B

    Topics: Bezafibrate; Bile Acids and Salts; Cholesterol; Clofibrate; Fenofibrate; Gemfibrozil; Humans; Hypolipidemic Agents; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Liver; Pentanoic Acids; Triglycerides

1987
Drug interactions with fibric acids.
    Pharmacology & therapeutics, 1994, Volume: 63, Issue:2

    Topics: Anticoagulants; Bezafibrate; Clofibrate; Clofibric Acid; Contraceptives, Oral; Coronary Disease; Drug Interactions; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hyperlipidemias; Hypoglycemic Agents; Hypolipidemic Agents; Lipids

1994
[Overviews of fibrate].
    Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59 Suppl 3

    Topics: Animals; Anticholesteremic Agents; Arteriosclerosis; Bezafibrate; Cholesterol, HDL; Cholesterol, LDL; Clofibrate; Coronary Disease; Diabetes Complications; Diabetes Mellitus; Humans; Hyperlipidemias; Hypolipidemic Agents; Randomized Controlled Trials as Topic; Triglycerides

2001
[Fibrates: mechanism of action, effect on levels of lipids and lipoproteins, risk of coronary events. Part 1. Clofibrate, gemfibrosil, besafibrate].
    Kardiologiia, 2004, Volume: 44, Issue:2

    Topics: Bezafibrate; Clofibrate; Female; Gemfibrozil; Humans; Hypertriglyceridemia; Hypolipidemic Agents; Lipoproteins; Male; Randomized Controlled Trials as Topic

2004
Fibrates.
    Handbook of experimental pharmacology, 2005, Issue:170

    Topics: Animals; Atherosclerosis; Bezafibrate; Cholesterol; Clofibrate; Endothelium, Vascular; Fenofibrate; Humans; Hypolipidemic Agents; Lipid Metabolism; PPAR alpha

2005
Statins, fibrates, and melanoma risk: a systematic review and meta-analysis.
    Journal of the National Cancer Institute, 2006, Nov-01, Volume: 98, Issue:21

    Topics: Atorvastatin; Bezafibrate; Clofibrate; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Incidence; Lovastatin; Melanoma; Odds Ratio; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic; Reproducibility of Results; Simvastatin; Skin Neoplasms; United States

2006
Fibrates for secondary prevention of cardiovascular disease and stroke.
    The Cochrane database of systematic reviews, 2015, Oct-25, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Bezafibrate; Cardiovascular Diseases; Cause of Death; Cholesterol, HDL; Clofibrate; Coronary Disease; Female; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hypertriglyceridemia; Male; Middle Aged; Myocardial Infarction; Randomized Controlled Trials as Topic; Secondary Prevention; Stroke

2015

Trials

17 trial(s) available for clofibrate and bezafibrate

ArticleYear
Effects of fibric acid derivatives on biliary lipid composition.
    The American journal of medicine, 1987, Nov-27, Volume: 83, Issue:5B

    Topics: Bezafibrate; Clinical Trials as Topic; Clofibrate; Clofibric Acid; Double-Blind Method; Female; Fenofibrate; Fibric Acids; Humans; Hyperlipoproteinemia Type II; Hypolipidemic Agents; Male; Propionates; Random Allocation

1987
Hypolipidemic effects of bezafibrate: studies in Italy.
    Monographs on atherosclerosis, 1986, Volume: 14

    Topics: Bezafibrate; Clinical Trials as Topic; Clofibrate; Double-Blind Method; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemias; Lipids; Lipoproteins; Random Allocation

1986
Diurnal lipid and lipoprotein profiles in hypertriglyceridemic patients with bezafibrate and clofibrate.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1986, Volume: 186, Issue:6

    Topics: Adult; Aged; Bezafibrate; Circadian Rhythm; Clofibrate; Dietary Fats; Double-Blind Method; Female; Humans; Hyperlipidemias; Lipids; Lipoproteins; Male; Middle Aged; Triglycerides

1986
Diurnal lipid and lipoprotein profiles with bezafibrate and clofibrate in healthy volunteers.
    Pharmatherapeutica, 1985, Volume: 4, Issue:5

    Topics: Adult; Bezafibrate; Cholesterol; Circadian Rhythm; Clofibrate; Half-Life; Humans; Lipids; Lipoproteins; Male; Triglycerides

1985
[Therapeutic effects of bezafibrate in hyperlipidemia].
    Casopis lekaru ceskych, 1983, May-20, Volume: 122, Issue:20

    Topics: Adult; Aged; Bezafibrate; Clinical Trials as Topic; Clofibrate; Clofibric Acid; Female; Humans; Hyperlipidemias; Hypolipidemic Agents; Male; Middle Aged

1983
[The effect of bezafibrate on biliary lipids (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1980, Feb-01, Volume: 122, Issue:5

    Topics: Adult; Bezafibrate; Bile; Clofibrate; Clofibric Acid; Drug Evaluation; Humans; Hyperlipoproteinemias; Lipids

1980
[Carbohydrate metabolism in bezafibrate therapy. Controlled study of glibenclamide-treated diabetics with hyperlipidemia].
    MMW, Munchener medizinische Wochenschrift, 1982, May-28, Volume: 124, Issue:21

    Topics: Aged; Bezafibrate; Carbohydrate Metabolism; Clinical Trials as Topic; Clofibrate; Clofibric Acid; Diabetes Complications; Diabetes Mellitus; Glyburide; Humans; Hyperlipidemias; Hypolipidemic Agents; Middle Aged; Patient Compliance

1982
Effect of bezafibrate on plasma lipids, lipoproteins, apolipoproteins AI, AII and B and LCAT activity in hyperlipidemic, non-insulin-dependent diabetics.
    Atherosclerosis, 1982, Volume: 43, Issue:2-3

    Topics: Aged; Apolipoprotein A-II; Apolipoproteins; Apolipoproteins A; Apolipoproteins B; Bezafibrate; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Clofibrate; Clofibric Acid; Diabetes Mellitus; Female; Humans; Hyperlipoproteinemias; Lipids; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Phosphatidylcholine-Sterol O-Acyltransferase

1982
[Lipid-lowering effect of etofibrate, bezafibrate and xanthinol nicotinate in patients with hyperlipoproteinemias].
    Therapie der Gegenwart, 1982, Volume: 121, Issue:5

    Topics: Bezafibrate; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Clofibrate; Clofibric Acid; Female; Humans; Hyperlipoproteinemias; Hypolipidemic Agents; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Middle Aged; Theophylline; Xanthinol Niacinate

1982
[Comparative double-blind investigation of bezafibrate and clofibrate in patients with primary hyperlipoproteinaemia].
    Wiener klinische Wochenschrift, 1980, Feb-01, Volume: 92, Issue:3

    Topics: Bezafibrate; Cholesterol; Clofibrate; Clofibric Acid; Female; Humans; Hyperlipoproteinemias; Male; Placebos; Triglycerides

1980
Steady-state kinetics of bezafibrate and clofibrate in healthy female volunteers.
    European journal of clinical pharmacology, 1980, Volume: 17, Issue:4

    Topics: Administration, Oral; Adult; Bezafibrate; Clinical Trials as Topic; Clofibrate; Clofibric Acid; Drug Administration Schedule; Female; Half-Life; Humans; Hypolipidemic Agents; Kinetics

1980
[Comparison of the lipid-lowering agents clofibrate and bezafibrate in patients with hyperlipoproteinemias IIa and IIb].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1981, Jul-01, Volume: 36, Issue:13

    Topics: Adult; Bezafibrate; Cholesterol; Clinical Trials as Topic; Clofibrate; Clofibric Acid; Double-Blind Method; Female; Humans; Hyperlipoproteinemia Type II; Male; Middle Aged; Random Allocation; Triglycerides

1981
Comparative study of once and 3-times daily regimens of bezafibrate in patients with primary hyperlipoproteinaemia.
    Current medical research and opinion, 1981, Volume: 7, Issue:8

    Topics: Adult; Aged; Alkaline Phosphatase; Bezafibrate; Cholesterol; Clinical Trials as Topic; Clofibrate; Clofibric Acid; Creatinine; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hyperlipoproteinemias; Hypolipidemic Agents; Lipids; Male; Middle Aged; Urea

1981
Improvement of hyperlipidaemia by bezafibrate treatment in RDT patients.
    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1981, Volume: 18

    Topics: Adult; Bezafibrate; Cholesterol; Clinical Trials as Topic; Clofibrate; Clofibric Acid; Humans; Hyperlipidemias; Hypolipidemic Agents; Kidney Failure, Chronic; Middle Aged; Renal Dialysis; Triglycerides

1981
[Efficacy of bezafibrate and fenofibrate on elevated blood lipids in HLP type IIa, IIb and IV].
    Die Medizinische Welt, 1982, Apr-30, Volume: 33, Issue:17

    Topics: Adult; Aged; Anticholesteremic Agents; Bezafibrate; Clofibrate; Clofibric Acid; Female; Fenofibrate; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Hypolipidemic Agents; Lipids; Male; Middle Aged; Propionates

1982
Treatment of familial hypercholesterolemia with a combination of bezafibrate and guar.
    Atherosclerosis, 1982, Volume: 45, Issue:3

    Topics: Adult; Apolipoproteins; Bezafibrate; Body Weight; Cholesterol; Cholesterol, LDL; Clofibrate; Clofibric Acid; Drug Therapy, Combination; Female; Galactans; Humans; Hyperlipoproteinemia Type II; Lipoproteins, LDL; Male; Mannans; Middle Aged; Plant Gums; Polysaccharides

1982
[Treatment of hyperlipoproteinaemia in diabetic patients (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1981, Dec-04, Volume: 106, Issue:49

    Topics: Adult; Aged; Bezafibrate; Blood Glucose; Cholesterol; Clofibrate; Clofibric Acid; Diabetes Complications; Female; Humans; Hyperlipoproteinemias; Hypolipidemic Agents; Male; Middle Aged; Phospholipids; Placebos; Triglycerides

1981

Other Studies

99 other study(ies) available for clofibrate and bezafibrate

ArticleYear
Characterization of the drug binding specificity of rat liver fatty acid binding protein.
    Journal of medicinal chemistry, 2008, Jul-10, Volume: 51, Issue:13

    Topics: Anilino Naphthalenesulfonates; Animals; Fatty Acid-Binding Proteins; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Fluorescence; Substrate Specificity

2008
Design, synthesis and hypolipidemic activity of novel 2-(m-tolyloxy) isobutyric acid derivatives.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:6

    Topics: Animals; Cholesterol; Cholesterol, Dietary; Disease Models, Animal; Drug Design; Gemfibrozil; Hypolipidemic Agents; Male; Molecular Structure; Propionates; Rats; Rats, Wistar; Stereoisomerism; Triglycerides

2009
Probing the fibrate binding specificity of rat liver fatty acid binding protein.
    Journal of medicinal chemistry, 2009, Sep-10, Volume: 52, Issue:17

    Topics: Animals; Binding Sites; Carboxylic Acids; Clofibric Acid; Esters; Fatty Acid-Binding Proteins; Fenofibrate; Hypolipidemic Agents; Ligands; Liver; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Rats; Spectrometry, Fluorescence; Substrate Specificity; Temperature; Thermodynamics

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Molecular characterization of zebrafish Oatp1d1 (Slco1d1), a novel organic anion-transporting polypeptide.
    The Journal of biological chemistry, 2013, Nov-22, Volume: 288, Issue:47

    Topics: Animals; Evolution, Molecular; Glycosylation; Gonadal Steroid Hormones; HEK293 Cells; Humans; Ion Transport; Organic Anion Transporters; Protein Multimerization; Zebrafish; Zebrafish Proteins

2013
[A comparison of bezafibrate and clofibrate in type II B and type IV hyperlipoproteinemia].
    Acta medica Austriaca, 1979, Volume: 6, Issue:3

    Topics: Adult; Aged; Bezafibrate; Clofibrate; Clofibric Acid; Dose-Response Relationship, Drug; Female; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Hypolipidemic Agents; Male; Middle Aged

1979
Involvement of calmodulin- and protein kinase C-related mechanism in an induction process of peroxisomal fatty acid oxidation-related enzymes by hypolipidemic peroxisome proliferators.
    Biochimica et biophysica acta, 1992, Apr-30, Volume: 1135, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bezafibrate; Body Weight; Calmodulin; Catalase; Cells, Cultured; Clofibrate; Diethylhexyl Phthalate; Electrophoresis, Polyacrylamide Gel; Isoquinolines; Kinetics; Liver; Male; Membrane Proteins; Microbodies; Molecular Weight; Organ Size; Oxidation-Reduction; Piperazines; Protein Kinase C; Pyrimidines; Rats; Rats, Inbred Strains; Reference Values; Trifluoperazine

1992
Further possibilities of using aryloxycarbonic acid derivatives in clinical practice.
    Folia biologica, 1991, Volume: 37, Issue:2

    Topics: Anticholesteremic Agents; Bezafibrate; Clofibrate; Connective Tissue Diseases; Fenofibrate; Humans; Lymphocyte Activation; Phytohemagglutinins

1991
Lack of induction of hepatic DNA damage on long-term administration of peroxisome proliferators in male F-344 rats.
    Toxicology, 1991, Volume: 69, Issue:1

    Topics: Animals; Bezafibrate; Clofibrate; Diethylhexyl Phthalate; DNA Damage; DNA, Single-Stranded; Lipid Peroxidation; Liver; Male; Oxidation-Reduction; Rats; Rats, Inbred F344

1991
Effect of ciprofibrate, bezafibrate, and LY171883 on peroxisomal beta-oxidation in cultured rat, dog, and rhesus monkey hepatocytes.
    Toxicology and applied pharmacology, 1990, Volume: 104, Issue:3

    Topics: Acetophenones; Animals; Autacoids; Azoles; Bezafibrate; Cells, Cultured; Clofibrate; Clofibric Acid; Dexamethasone; Dogs; Dose-Response Relationship, Drug; Female; Fibric Acids; Glucagon; Hypolipidemic Agents; In Vitro Techniques; Liver; Male; Microbodies; Microscopy, Electron; NAD; Oxidation-Reduction; Rats; Tetrazoles; Tyrosine Transaminase

1990
Fibrates and triglyceride metabolism.
    European journal of clinical pharmacology, 1991, Volume: 40 Suppl 1

    Topics: Bezafibrate; Clofibrate; Fenofibrate; Gemfibrozil; Humans; Hypolipidemic Agents; Triglycerides

1991
Comparative studies on the influence of different fibrates on serum lipoproteins in endogenous hyperlipoproteinaemia.
    European journal of clinical pharmacology, 1991, Volume: 40, Issue:1

    Topics: Adult; Aged; Bezafibrate; Cholesterol; Clofibrate; Clofibric Acid; Colestipol; Female; Fenofibrate; Gemfibrozil; Humans; Hyperlipoproteinemias; Hypolipidemic Agents; Lipoproteins; Male; Middle Aged; Probucol

1991
Tumour radiosensitization by clofibrate and its analogs: possible mechanisms.
    Advances in experimental medicine and biology, 1990, Volume: 277

    Topics: Animals; Bezafibrate; Clofibrate; Combined Modality Therapy; Etanidazole; Female; Hypoxia; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Regional Blood Flow

1990
Induction of fatty acid binding protein by peroxisome proliferators in primary hepatocyte cultures and its relationship to the induction of peroxisomal beta-oxidation.
    Biochimica et biophysica acta, 1990, Apr-23, Volume: 1034, Issue:1

    Topics: Animals; Bezafibrate; Carrier Proteins; Cell Division; Cells, Cultured; Clofibrate; Epoxy Compounds; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fatty Acids; Liver; Male; Microbodies; Neoplasm Proteins; Nerve Tissue Proteins; Oxidation-Reduction; Palmitoyl Coenzyme A; Rats; Rats, Inbred Strains

1990
Comparison of crystal and solution hemoglobin binding of selected antigelling agents and allosteric modifiers.
    Biochemistry, 1990, Apr-24, Volume: 29, Issue:16

    Topics: Allosteric Regulation; Antisickling Agents; Benzyl Compounds; Bezafibrate; Carboxylic Acids; Clofibrate; Hemoglobin A; Humans; Myoglobin; Protein Binding; Protein Conformation; Solutions; Structure-Activity Relationship

1990
Long-term effects of peroxisome proliferators on the balance between hydrogen peroxide-generating and scavenging capacities in the liver of Fischer-344 rats.
    Toxicology, 1990, Volume: 63, Issue:2

    Topics: Acyl-CoA Oxidase; Animals; Bezafibrate; Cells, Cultured; Clofibrate; Cytosol; Diethylhexyl Phthalate; Enzyme Activation; Hydrogen Peroxide; Liver; Liver Neoplasms, Experimental; Male; Microbodies; Microscopy, Electron; Oxidoreductases; Phthalic Acids; Rats; Rats, Inbred F344; Time Factors

1990
Altered radiosensitivity in a mouse carcinoma after administration of clofibrate and bezafibrate.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1989, Volume: 15, Issue:1

    Topics: Animals; Bezafibrate; Carcinoma; Clofibrate; Mice; Oxyhemoglobins; Radiation Tolerance; Radiation-Sensitizing Agents

1989
Blood pressure, cigarette smoking and heart attack in the WHO co-operative trial of clofibrate.
    International journal of epidemiology, 1989, Volume: 18, Issue:2

    Topics: Bezafibrate; Clofibrate; Coronary Disease; Fibrinogen; Humans; Hypertension; Male; Smoking; World Health Organization

1989
Effects of treatment with clofibrate, bezafibrate, and ciprofibrate on the metabolism of cholesterol in rat liver microsomes.
    Journal of lipid research, 1989, Volume: 30, Issue:7

    Topics: Animals; Bezafibrate; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Clofibrate; Clofibric Acid; Fibric Acids; Hydroxymethylglutaryl CoA Reductases; Hypolipidemic Agents; Male; Microsomes, Liver; Rats; Rats, Inbred Strains; Sterol O-Acyltransferase

1989
Adipose conversion of cultured rat primary preadipocytes by hypolipidemic drugs.
    Biochimica et biophysica acta, 1986, Jun-27, Volume: 877, Issue:2

    Topics: Adipose Tissue; Animals; Bezafibrate; Bucladesine; Cell Differentiation; Cells, Cultured; Clofibrate; Cyclic AMP; Glycerolphosphate Dehydrogenase; Hypolipidemic Agents; Lipase; Lipoprotein Lipase; Male; Rats; Triglycerides

1986
Fatty acid metabolism in hepatocytes cultured with hypolipidaemic drugs. Role of carnitine.
    The Biochemical journal, 1988, Jul-01, Volume: 253, Issue:1

    Topics: Animals; Bezafibrate; Carnitine; Carnitine O-Acetyltransferase; Carnitine O-Palmitoyltransferase; Cells, Cultured; Clofibrate; Clofibric Acid; Fatty Acids; Fibric Acids; Glucagon; Humans; Hypolipidemic Agents; Insulin; Liver; Male; Rats; Rats, Inbred Strains

1988
Gemfibrozil increases both apo A-I and apo E concentrations. Comparison to other lipid regulators in cholesterol-fed rats.
    Atherosclerosis, 1986, Volume: 59, Issue:1

    Topics: Animals; Apolipoprotein A-I; Apolipoproteins A; Apolipoproteins E; Bezafibrate; Cholesterol, Dietary; Cholesterol, HDL; Clofibrate; Clofibric Acid; Fenofibrate; Fibric Acids; Gemfibrozil; Male; Pentanoic Acids; Rats; Rats, Inbred Strains; Valerates

1986
Assessment of gastric antisecretory effects of phenoxyisobutyrate derivatives in the rat and the mouse.
    Scandinavian journal of gastroenterology, 1988, Volume: 23, Issue:9

    Topics: Administration, Oral; Animals; Bezafibrate; Carcinoid Tumor; Clofibrate; Clofibric Acid; Fibric Acids; Gastric Juice; Male; Mice; Mice, Inbred Strains; Rats; Rats, Inbred F344; Species Specificity; Stomach Neoplasms; Time Factors

1988
A little more information about aggravation of probucol-induced HDL-reduction by clofibrate.
    Atherosclerosis, 1988, Volume: 70, Issue:1-2

    Topics: Adult; Aged; Bezafibrate; Cholesterol, HDL; Clofibrate; Drug Interactions; Drug Therapy, Combination; Female; Humans; Lipoproteins, HDL; Male; Middle Aged; Phenols; Probucol

1988
Interactions of inhibitors of carnitine palmitoyltransferase I and fibrates in cultured hepatocytes.
    The Biochemical journal, 1988, Jul-01, Volume: 253, Issue:1

    Topics: Acyltransferases; Animals; Bezafibrate; Carnitine O-Palmitoyltransferase; Cells, Cultured; Clofibrate; Clofibric Acid; Epoxy Compounds; Ethers, Cyclic; Fatty Acids; Fibric Acids; Isoenzymes; Liver; Male; Rats; Rats, Inbred Strains; Time Factors; Triglycerides

1988
The modification of hemoglobin affinity for oxygen and tumor radiosensitivity by antilipidemic drugs.
    Radiation research, 1987, Volume: 112, Issue:1

    Topics: Animals; Bezafibrate; Clofibrate; Combined Modality Therapy; Gemfibrozil; Hemoglobins; Hypolipidemic Agents; Mice; Neoplasm Transplantation; Oxygen; Pentanoic Acids; Radiation-Sensitizing Agents; Sarcoma, Experimental

1987
Ethyl 2-([5,6-dihydro-7-(1H-imidazol-1-yl)-2-naphthalenyl]oxy)- 2-methylpropanoate as a new potent oxyisobutyrate hypolipidaemic with unusual features.
    Il Farmaco; edizione scientifica, 1987, Volume: 42, Issue:3

    Topics: Animals; Bezafibrate; Chemical Phenomena; Chemistry; Cholesterol; Clofibrate; Diet; Hypercholesterolemia; Hypolipidemic Agents; Imidazoles; Lipoproteins, LDL; Male; Naphthalenes; Rats

1987
Bezafibrate lowers oxygen affinity of haemoglobin.
    Lancet (London, England), 1983, Oct-15, Volume: 2, Issue:8355

    Topics: 2,3-Diphosphoglycerate; Anemia, Sickle Cell; Bezafibrate; Clofibrate; Diphosphoglyceric Acids; Drug Synergism; Erythrocytes; Hemoglobin A; Hemoglobin, Sickle; Humans; Oxygen; Solubility

1983
Effects of bezafibrate on receptor-mediated and receptor-independent low density lipoprotein catabolism in type II hyperlipoproteinaemic subjects.
    Atherosclerosis, 1982, Volume: 44, Issue:3

    Topics: Adult; Apolipoproteins; Apolipoproteins B; Bezafibrate; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Clofibrate; Clofibric Acid; Female; Humans; Hyperlipoproteinemia Type II; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Middle Aged; Receptors, Cell Surface; Receptors, LDL

1982
Some comparative effects of gemfibrozil, clofibrate, bezafibrate, cholestyramine and compactin on sterol metabolism in rats.
    Atherosclerosis, 1983, Volume: 48, Issue:3

    Topics: Animals; Anticholesteremic Agents; Bezafibrate; Caprylates; Carbon Radioisotopes; Cholesterol; Cholesterol, Dietary; Cholestyramine Resin; Clofibrate; Gemfibrozil; Hypolipidemic Agents; Liver; Lovastatin; Male; Mevalonic Acid; Naphthalenes; Pentanoic Acids; Rats; Rats, Inbred F344; Sterols; Valerates

1983
Effects of clofibrate, bezafibrate, fenofibrate and probucol on plasma lipolytic enzymes in normolipaemic subjects.
    European journal of clinical pharmacology, 1983, Volume: 25, Issue:1

    Topics: Adult; Bezafibrate; Cholesterol; Clofibrate; Fenofibrate; Humans; Hypolipidemic Agents; Lipase; Lipolysis; Lipoprotein Lipase; Male; Phosphatidylcholine-Sterol O-Acyltransferase; Probucol; Triglycerides

1983
[Improvement in diabetes control by treatment with bezafibrate].
    Deutsche medizinische Wochenschrift (1946), 1982, Oct-01, Volume: 107, Issue:39

    Topics: Aged; Bezafibrate; Cholesterol; Clofibrate; Clofibric Acid; Diabetes Complications; Diabetes Mellitus; Female; Humans; Hyperlipidemias; Insulin; Male; Sulfonylurea Compounds; Triglycerides

1982
Reduced LDL- and increased HDL-apoproteins in patients with hypercholesterolaemia under treatment with bezafibrate.
    Atherosclerosis, 1981, Volume: 40, Issue:2

    Topics: Adult; Aged; Apolipoprotein A-I; Apolipoprotein A-II; Apolipoproteins; Apolipoproteins B; Bezafibrate; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Clofibrate; Clofibric Acid; Female; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Middle Aged; Triglycerides

1981
[Bezafibrate and delayed action etofibrate in hyperlipidemia].
    Deutsche medizinische Wochenschrift (1946), 1983, Feb-25, Volume: 108, Issue:8

    Topics: Bezafibrate; Body Weight; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Clofibrate; Clofibric Acid; Delayed-Action Preparations; Humans; Hyperlipidemias; Lipoproteins, HDL; Lipoproteins, LDL; Triglycerides

1983
The effect of bezafibrate and clofibrate on cholesterol ester metabolism in rabbit peritoneal macrophages stimulated with acetylated low density lipoproteins.
    Experimental and molecular pathology, 1983, Volume: 38, Issue:1

    Topics: Animals; Ascitic Fluid; Bezafibrate; Cholesterol Esters; Clofibrate; Clofibric Acid; Lipoproteins, LDL; Macrophages; Rabbits; Sterol Esterase; Sterol O-Acyltransferase

1983
Elevation of high density lipoprotein cholesterol (cHDL) and reduction of the total cholesterol/cHDL index in the treatment of hyperlipoproteinaemias IIb and IV with bezafibrate.
    Current medical research and opinion, 1983, Volume: 8, Issue:5

    Topics: Adult; Aged; Bezafibrate; Cholesterol; Cholesterol, HDL; Clofibrate; Clofibric Acid; Female; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Hypolipidemic Agents; Lipoproteins, HDL; Male; Middle Aged; Triglycerides

1983
The short- and long-term effects of bezafibrate in the rat.
    Annals of the New York Academy of Sciences, 1982, Volume: 386

    Topics: Animals; Bezafibrate; Carnitine O-Acetyltransferase; Catalase; Cholesterol; Clofibrate; Clofibric Acid; Female; Hypolipidemic Agents; Kinetics; Liver; Male; Microbodies; Microscopy, Electron; Organ Size; Organoids; Rats; Rats, Inbred Strains; Triglycerides

1982
Effects of bezafibrate on the serum lipoprotein lipid and apolipoprotein composition, lipoprotein triglyceride removal capacity and the fatty acid composition of the plasma lipid esters.
    Atherosclerosis, 1980, Volume: 37, Issue:2

    Topics: Adult; Apolipoproteins; Bezafibrate; Blood Glucose; Body Weight; Cholesterol; Clofibrate; Clofibric Acid; Esters; Fatty Acids; Female; Humans; Insulin; Lipids; Lipoproteins; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Middle Aged; Triglycerides

1980
The effect of bezafibrate and clofibrate on cholesterol ester metabolism in 3T3 cells in smooth muscle cells in tissue culture.
    Experimental and molecular pathology, 1982, Volume: 36, Issue:2

    Topics: Animals; Aorta; Bezafibrate; Cell Line; Cholesterol; Cholesterol Esters; Clofibrate; Clofibric Acid; Culture Techniques; Lipoproteins, LDL; Mice; Muscle, Smooth, Vascular; Swine

1982
[Bezafibrate in primary hyperlipidemias (author's transl)].
    Klinische Wochenschrift, 1982, Jan-15, Volume: 60, Issue:2

    Topics: Bezafibrate; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Clofibrate; Clofibric Acid; Female; Humans; Hyperlipidemias; Hyperlipoproteinemias; Lipoprotein Lipase; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged

1982
Effects of bezafibrate on the composition of very low density lipoproteins in type IV hyperlipoproteinemia.
    Atherosclerosis, 1982, Volume: 42, Issue:2-3

    Topics: Apolipoprotein C-I; Apolipoprotein C-II; Apolipoproteins; Apolipoproteins C; Apolipoproteins E; Bezafibrate; Cholesterol; Clofibrate; Clofibric Acid; Humans; Hyperlipoproteinemia Type IV; Hypolipidemic Agents; Lipoproteins, VLDL; Male; Protein Conformation; Triglycerides

1982
Specificity in the action of hypolipidemic drugs: increase of peroxisomal beta-oxidation largely dissociated from hepatomegaly and peroxisome proliferation in the rat.
    Journal of lipid research, 1982, Volume: 23, Issue:2

    Topics: Animals; Bezafibrate; Cell Division; Cell Fractionation; Clofibrate; Clofibric Acid; Female; Hepatomegaly; Hypolipidemic Agents; Male; Microbodies; Organ Size; Organoids; Rats; Rats, Inbred F344; Sex Factors

1982
Bezafibrate: lack of effect on creatinine excretion and muscular proteins.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1982, Volume: 180, Issue:1

    Topics: Bezafibrate; Clofibrate; Clofibric Acid; Creatine Kinase; Creatinine; Female; Humans; Hyperlipoproteinemias; Hypolipidemic Agents; Isoenzymes; Kidney; Male; Middle Aged; Muscle Proteins; Muscles; Myoglobinuria

1982
Elevated lipoprotein lipase activity in skeletal muscle tissue during treatment of hypertriglyceridaemic patients with bezafibrate.
    Atherosclerosis, 1982, Volume: 44, Issue:1

    Topics: Adipose Tissue; Adult; Bezafibrate; Clofibrate; Clofibric Acid; Female; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Hypolipidemic Agents; Lipoprotein Lipase; Male; Middle Aged; Muscles

1982
[Fat and renal failure--therapeutic aspects].
    Klinische Wochenschrift, 1982, Volume: 60, Issue:15

    Topics: Acute Kidney Injury; Animals; Bezafibrate; Carnitine; Charcoal; Clofibrate; Clofibric Acid; Humans; Hyperlipoproteinemias; Hypolipidemic Agents; Infusions, Parenteral; Kidney Failure, Chronic; Lipids; Physical Exertion; Rats; Renal Dialysis

1982
Treatment of uremic hypertriglyceridaemia with bezafibrate.
    Atherosclerosis, 1982, Volume: 44, Issue:2

    Topics: Bezafibrate; Cholesterol; Clofibrate; Clofibric Acid; Female; Humans; Hyperlipidemias; Kidney Failure, Chronic; Lipid Metabolism; Lipoproteins; Male; Triglycerides

1982
Bezafibrate treatment in primary hypercholesterolaemia. Possibility of intermittent treatment.
    Atherosclerosis, 1982, Volume: 44, Issue:3

    Topics: Animals; Bezafibrate; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Clofibrate; Clofibric Acid; Humans; Hypercholesterolemia; Lipoproteins, HDL; Lipoproteins, LDL; Mice; Microbodies; Rats; Time Factors

1982
The effect of bezafibrate and clofibrate on microsomal ACAT and lysosomal cholesterol ester hydrolase activity in the cholesterol-fed rabbit aorta.
    Atherosclerosis, 1982, Volume: 45, Issue:1

    Topics: Acyltransferases; Animals; Aorta; Bezafibrate; Carboxylic Ester Hydrolases; Clofibrate; Clofibric Acid; Female; Hypolipidemic Agents; Lysosomes; Rabbits; Regression Analysis; Sterol Esterase; Sterol O-Acyltransferase

1982
[Effect of bezafibrate on lipid and apoprotein levels in patients with idiopathic hypertriglyceridemia].
    Kardiologia polska, 1982, Volume: 25, Issue:7-8

    Topics: Adult; Aged; Apolipoproteins; Bezafibrate; Cholesterol; Clofibrate; Clofibric Acid; Female; Humans; Hyperlipoproteinemia Type III; Hyperlipoproteinemia Type IV; Hypolipidemic Agents; Male; Middle Aged; Triglycerides

1982
[Effect of bezafibrate on the carbohydrate metabolism of 17 diabetics with hyperlipidemia].
    Die Medizinische Welt, 1981, Feb-20, Volume: 32, Issue:8

    Topics: Anticholesteremic Agents; Bezafibrate; Body Weight; Carbohydrate Metabolism; Clofibrate; Clofibric Acid; Diabetes Complications; Humans; Hyperlipidemias; Placebos

1981
"In vitro" metabolism of bezafibrate by rat liver.
    Pharmacological research communications, 1981, Volume: 13, Issue:2

    Topics: Animals; Bezafibrate; Clofibrate; Clofibric Acid; Cytochrome P-450 Enzyme System; Hydroxylation; Hypolipidemic Agents; In Vitro Techniques; Kinetics; Liver; Microsomes, Liver; Mixed Function Oxygenases; Oxidation-Reduction; Rats; Subcellular Fractions

1981
Effect of bezafibrate on the high-density lipoprotein subfractions HDL2 and HDL3 in primary hyperlipoproteinemia type IV.
    Artery, 1980, Volume: 7, Issue:6

    Topics: Adult; Apolipoproteins; Bezafibrate; Cholesterol; Clofibrate; Clofibric Acid; Humans; Hyperlipoproteinemia Type IV; Lipids; Lipoproteins, HDL; Male; Middle Aged; Triglycerides

1980
Lipids and lipoproteins in hyperlipidemia type IIa during treatment with different lipid lowering drugs.
    Artery, 1980, Volume: 8, Issue:6

    Topics: Adolescent; Bezafibrate; Clofibrate; Clofibric Acid; Female; Humans; Hyperlipoproteinemia Type II; Inositol; Lipids; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Male; Nicotinic Acids; Nicotinyl Alcohol; Xanthinol Niacinate

1980
Clinical experience with bezafibrate.
    Artery, 1980, Volume: 8, Issue:6

    Topics: Bezafibrate; Blood Glucose; Body Weight; Cholesterol; Clofibrate; Clofibric Acid; Coronary Disease; Female; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Male; Triglycerides

1980
Effects of clofibric acid and bezafibrate administration on activities of alkaline phosphatase and other enzymes in livers of rats.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1981, Volume: 179, Issue:2

    Topics: Alkaline Phosphatase; Animals; Bezafibrate; Bilirubin; Clofibrate; Clofibric Acid; Glucuronates; Glucuronosyltransferase; Hexosyltransferases; Hypolipidemic Agents; Liver; Male; Microsomes, Liver; Rats; Rats, Inbred Strains

1981
[Rhabdomyolysis with acute renal failure due to bezafibrate].
    Klinische Wochenschrift, 1981, Apr-15, Volume: 59, Issue:8

    Topics: Acute Kidney Injury; Bezafibrate; Clofibrate; Clofibric Acid; Humans; Male; Middle Aged; Muscular Diseases

1981
Effects of bezafibrate on low HDL-cholesterol in patients with ischaemic cerebrovascular disease: a pilot study.
    The Journal of international medical research, 1981, Volume: 9, Issue:5

    Topics: Adult; Bezafibrate; Cerebral Infarction; Cholesterol; Cholesterol, HDL; Clofibrate; Clofibric Acid; Humans; Hypolipidemic Agents; Ischemic Attack, Transient; Lipoproteins, HDL; Male; Middle Aged

1981
Acute muscular syndrome after bezafibrate.
    Klinische Wochenschrift, 1981, Dec-01, Volume: 59, Issue:23

    Topics: Bezafibrate; Clofibrate; Clofibric Acid; Dose-Response Relationship, Drug; Humans; Hypolipidemic Agents; Myoglobinuria

1981
Clinical pharmacokinetics of bezafibrate in patients with impaired renal function.
    European journal of clinical pharmacology, 1981, Volume: 21, Issue:3

    Topics: Adult; Aged; Bezafibrate; Clofibrate; Clofibric Acid; Creatinine; Female; Humans; Hyperlipidemias; Hypolipidemic Agents; Kidney Failure, Chronic; Kinetics; Male; Middle Aged

1981
Comparative pharmacokinetics of 400 mg bezafibrate after a single oral administration of a new slow-release preparation and the currently available commercial form.
    The Journal of international medical research, 1981, Volume: 9, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Bezafibrate; Clofibrate; Clofibric Acid; Delayed-Action Preparations; Female; Humans; Hypolipidemic Agents; Kinetics; Male

1981
Effect of the hypolipidemic drug bezafibrate on the hepatic mixed function oxidase system of the rat: heterogeneity monooxygenase responses.
    Pharmacological research communications, 1981, Volume: 13, Issue:9

    Topics: Animals; Bezafibrate; Clofibrate; Clofibric Acid; Cytochrome P-450 Enzyme System; Hypolipidemic Agents; Liver; Male; Mixed Function Oxygenases; Oxidoreductases; Rats; Rats, Inbred Strains; Spectrum Analysis

1981
Pharmacokinetics of bezafibrate after single and multiple doses in the presence of renal failure.
    Klinische Wochenschrift, 1980, Sep-01, Volume: 58, Issue:17

    Topics: Adult; Bezafibrate; Clofibrate; Clofibric Acid; Drug Administration Schedule; Female; Humans; Kidney Diseases; Kinetics; Male; Middle Aged

1980
[The therapeutic efficacy of bezafibrate in hyperlipoproteinemias of various types].
    Schweizerische medizinische Wochenschrift, 1980, Dec-06, Volume: 110, Issue:49

    Topics: Bezafibrate; Cholesterol; Clofibrate; Clofibric Acid; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Hyperlipoproteinemia Type V; Hyperlipoproteinemias; Lipoproteins, HDL; Triglycerides

1980
Changes in lipids and lipoproteins in patients with hyperlipidemia type IIb, IV and V treated with different lipid lowering drugs.
    Artery, 1980, Volume: 8, Issue:2

    Topics: Anticholesteremic Agents; Bezafibrate; Cholesterol; Clofibrate; Clofibric Acid; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Hyperlipoproteinemia Type V; Inositol; Lipoproteins; Nicotinic Acids; Xanthinol Niacinate

1980
The effect of etofibrate retard, bezafibrate and procetofen.
    Artery, 1980, Volume: 8, Issue:2

    Topics: Aged; Bezafibrate; Cholesterol; Clofibrate; Clofibric Acid; Female; Fenofibrate; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Lipoproteins; Male; Middle Aged; Patient Compliance; Propionates; Triglycerides

1980
[Clofibrate therapy in hypercholesterolemia. Reports on medium-long-term movements of HDL- cholesterol by the action of clofibrate].
    Fortschritte der Medizin, 1980, Dec-04, Volume: 98, Issue:45

    Topics: Adult; Bezafibrate; Clofibrate; Clofibric Acid; Drug Administration Schedule; Female; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Male; Middle Aged

1980
Selective modification of rat hepatic microsomal fatty acid chain elongation and desaturation by fibrates: relationship with peroxisome proliferation.
    British journal of pharmacology, 1995, Volume: 114, Issue:7

    Topics: Acetyltransferases; Animals; Bezafibrate; Clofibrate; Dietary Fats; Fatty Acid Desaturases; Fatty Acid Elongases; Fatty Acids; Gemfibrozil; Male; Microbodies; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Time Factors

1995
Inhibition of neutral cholesterol ester hydrolase in rat liver by fibric acids and probucol in vitro.
    Biochemical Society transactions, 1994, Volume: 22, Issue:4

    Topics: Animals; Bezafibrate; Clofibrate; Cytosol; Kinetics; Liver; Male; Microsomes, Liver; Probucol; Rats; Sterol Esterase

1994
The effects of clofibrate and bezafibrate on cholesterol metabolism in the liver of the male rat.
    Lipids, 1994, Volume: 29, Issue:11

    Topics: Animals; Bezafibrate; Body Weight; Cholesterol; Cholesterol Esters; Clofibrate; Cytosol; Liver; Male; Microsomes, Liver; Rats; Rats, Wistar; Sterol Esterase; Sterol O-Acyltransferase

1994
Diverse mechanisms of calcium mobilization by peroxisome proliferators in rat hepatocytes.
    Toxicology and applied pharmacology, 1995, Volume: 130, Issue:2

    Topics: Animals; Anticholesteremic Agents; Antifungal Agents; Bezafibrate; Calcium; Clofibrate; Homeostasis; Imidazoles; In Vitro Techniques; Liver; Male; Microbodies; Pyrimidines; Rats; Rats, Wistar

1995
Relationship between plasma lipids and palmitoyl-CoA hydrolase and synthetase activities with peroxisomal proliferation in rats treated with fibrates.
    British journal of pharmacology, 1994, Volume: 112, Issue:2

    Topics: Animals; Bezafibrate; Cholesterol; Clofibrate; Coenzyme A Ligases; Diet; Gemfibrozil; Hypolipidemic Agents; Lipids; Liver; Male; Microbodies; Organ Size; Palmitoyl-CoA Hydrolase; Rats; Rats, Sprague-Dawley; Repressor Proteins; Saccharomyces cerevisiae Proteins; Triglycerides

1994
The effect of fibric acid derivatives on cholesterol metabolism in rat liver.
    Biochemical Society transactions, 1994, Volume: 22, Issue:2

    Topics: Animals; Bezafibrate; Cholesterol; Clofibrate; Liver; Male; Organ Size; Rats; Rats, Wistar; Sterol Esterase; Sterol O-Acyltransferase

1994
Growth inhibition of human vascular smooth muscle cells by fenofibrate: a possible therapy for restenosis.
    Cardiovascular research, 1994, Volume: 28, Issue:5

    Topics: Bezafibrate; Cell Division; Cells, Cultured; Clofibrate; Fenofibrate; Gemfibrozil; Graft Occlusion, Vascular; Humans; Muscle, Smooth; Platelet-Derived Growth Factor; Saphenous Vein

1994
Regulation of xanthine dehydrogenase in rat liver in response to peroxisome proliferators.
    Biochemical and biophysical research communications, 1993, Sep-15, Volume: 195, Issue:2

    Topics: Animals; Bezafibrate; Blotting, Western; Caprylates; Catalase; Clofibrate; Dehydroepiandrosterone; Diethylhexyl Phthalate; Fluorocarbons; Kinetics; Liver; Male; Microbodies; Rats; Rats, Wistar; Xanthine Dehydrogenase

1993
Cooperative effect of inositol hexakisphosphate, bezafibrate, and clofibric acid on the spectroscopic properties of the nitric oxide derivative of ferrous human hemoglobin.
    Journal of inorganic biochemistry, 1993, Volume: 50, Issue:4

    Topics: Bezafibrate; Clofibrate; Electron Spin Resonance Spectroscopy; Glycated Hemoglobin; Humans; Nitric Oxide; Phytic Acid; Spectrophotometry; Thermodynamics

1993
Increase of adipose differentiation by hypolipidemic fibrate drugs in Ob 17 preadipocytes: requirement for thyroid hormones.
    Biochimica et biophysica acta, 1993, May-08, Volume: 1177, Issue:1

    Topics: Adipose Tissue; Animals; Bezafibrate; Cell Differentiation; Cell Line; Cell Nucleus; Clofibrate; Fenofibrate; Gene Expression Regulation; Hypolipidemic Agents; Mice; Mice, Obese; Receptors, Thyroid Hormone; Thyroid Hormones; Thyroxine

1993
Fibrates induce mdr2 gene expression and biliary phospholipid secretion in the mouse.
    The Biochemical journal, 1996, Mar-15, Volume: 314 ( Pt 3)

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Bezafibrate; Bile; Bile Canaliculi; Clofibrate; Clofibric Acid; DNA Primers; Drug Resistance, Multiple; Fenofibrate; Fibric Acids; Gemfibrozil; Gene Expression; Hypolipidemic Agents; Liver; Male; Mice; Mice, Inbred Strains; Molecular Sequence Data; Multigene Family; Phospholipids; RNA, Messenger; RNA, Ribosomal, 18S

1996
Differential effects of fibrates on the acyl composition of microsomal phospholipids in rats.
    British journal of pharmacology, 1995, Volume: 116, Issue:3

    Topics: Animals; Bezafibrate; Cell Division; Clofibrate; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Gemfibrozil; Hypolipidemic Agents; Lipids; Liver; Male; Microbodies; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Rats, Sprague-Dawley; Time Factors

1995
Different effects of fibrates on the microsomal fatty acid chain elongation and the acyl composition of phospholipids in guinea-pigs.
    British journal of pharmacology, 1995, Volume: 116, Issue:8

    Topics: Animals; Bezafibrate; Clofibrate; Fatty Acid Synthases; Fatty Acids; Gemfibrozil; Guinea Pigs; Hypolipidemic Agents; Male; Microsomes, Liver; NADH Dehydrogenase; NADPH-Ferrihemoprotein Reductase; Palmitoyl-CoA Hydrolase; Phospholipids

1995
Growth regulation by peroxisome proliferators: opposing activities in early and late G1.
    Cancer research, 1996, Jul-15, Volume: 56, Issue:14

    Topics: Animals; Bezafibrate; Carcinogens; Cell Cycle; Cell Line; Clofibrate; Clofibric Acid; DNA; Fibric Acids; Gene Expression Regulation; Genes, Immediate-Early; Growth Substances; Mice; Microbodies; Pyrimidines; Signal Transduction; Time Factors; Transcriptional Activation

1996
Hypolipidemic activity of select fibrates correlates to changes in hepatic apolipoprotein C-III expression: a potential physiologic basis for their mode of action.
    Journal of lipid research, 1995, Volume: 36, Issue:12

    Topics: Animals; Apolipoprotein C-III; Apolipoproteins C; Bezafibrate; Cholesterol; Clofibrate; Fenofibrate; Gemfibrozil; Hypolipidemic Agents; Liver; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Triglycerides

1995
Decreased susceptibility to copper-induced oxidation of rat-lipoproteins after fibrate treatment: influence of fatty acid composition.
    British journal of pharmacology, 1996, Volume: 117, Issue:6

    Topics: Animals; Antioxidants; Bezafibrate; Clofibrate; Copper Sulfate; Fatty Acids; Gemfibrozil; Hypolipidemic Agents; Lipid Peroxidation; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Rats; Rats, Sprague-Dawley

1996
Evaluation of the phototoxic properties of some hypolipidemics in vitro: fenofibrate exhibits a prominent phototoxic potential in the UVA and UVB region.
    Journal of dermatological science, 1996, Volume: 13, Issue:2

    Topics: Bezafibrate; Clofibrate; Dermatitis, Phototoxic; Drug Evaluation, Preclinical; Fenofibrate; Gemfibrozil; Hemolysis; Humans; Hypolipidemic Agents; In Vitro Techniques; Ultraviolet Rays

1996
Hepatic microsomal enzyme induction, beta-oxidation, and cell proliferation following administration of clofibrate, gemfibrozil, or bezafibrate in the CD rat.
    Toxicology and applied pharmacology, 1997, Volume: 142, Issue:1

    Topics: Animals; Anticholesteremic Agents; Bezafibrate; Clofibrate; Cyclin-Dependent Kinases; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Induction; Female; Gemfibrozil; Isoenzymes; Liver; Male; Microbodies; Microsomes, Liver; Mixed Function Oxygenases; Organ Size; Oxidation-Reduction; Palmitoyl Coenzyme A; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred Strains; Sex Characteristics

1997
Peroxisome proliferator activated receptors in Atlantic salmon (Salmo salar): effects on PPAR transcription and acyl-CoA oxidase activity in hepatocytes by peroxisome proliferators and fatty acids.
    Biochimica et biophysica acta, 1997, Oct-18, Volume: 1348, Issue:3

    Topics: Acyl-CoA Oxidase; Animals; Base Sequence; Bezafibrate; Blotting, Northern; Clofibrate; DNA, Complementary; Fatty Acids; Humans; L-Lactate Dehydrogenase; Liver; Microbodies; Molecular Sequence Data; Oxidoreductases; Polymerase Chain Reaction; Receptors, Cytoplasmic and Nuclear; Salmon; Sequence Analysis, DNA; Sequence Homology; Transcription Factors; Transcription, Genetic

1997
No effect of fibrates on synthesis of apolipoprotein(a) in primary cultures of cynomolgus monkey and human hepatocytes: apolipoprotein A-I synthesis increased.
    Biochemical and biophysical research communications, 1998, Mar-17, Volume: 244, Issue:2

    Topics: Animals; Apolipoprotein A-I; Apolipoproteins A; Bezafibrate; Cells, Cultured; Clofibrate; Clofibric Acid; Gemfibrozil; Humans; Liver; Macaca fascicularis

1998
The effect of peroxisome proliferators on mitochondrial bioenergetics.
    Toxicological sciences : an official journal of the Society of Toxicology, 1999, Volume: 48, Issue:1

    Topics: Animals; Bezafibrate; Calcium; Clofibrate; Clofibric Acid; Diethylhexyl Phthalate; Energy Metabolism; Fenofibrate; Fibric Acids; Gemfibrozil; Intracellular Membranes; Male; Membrane Potentials; Mitochondria, Liver; Mitochondrial Swelling; Oxygen; Permeability; Peroxisome Proliferators; Pyrimidines; Rats; Rats, Sprague-Dawley; Trichloroethylene

1999
Activators of peroxisome proliferator-activated receptor-alpha induce the expression of the uncoupling protein-3 gene in skeletal muscle: a potential mechanism for the lipid intake-dependent activation of uncoupling protein-3 gene expression at birth.
    Diabetes, 1999, Volume: 48, Issue:6

    Topics: Animals; Bezafibrate; Carrier Proteins; Clofibrate; DNA-Binding Proteins; Eating; Fatty Acids, Nonesterified; Female; Gene Expression Regulation, Developmental; Hypolipidemic Agents; Ion Channels; Leptin; Male; Mice; Mitochondria, Muscle; Mitochondrial Proteins; Muscle Development; Muscle, Skeletal; Peroxisome Proliferators; Proteins; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation; Uncoupling Protein 3

1999
Gallstones in patients with rheumatoid arthritis.
    The Journal of rheumatology, 1999, Volume: 26, Issue:7

    Topics: Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Bezafibrate; C-Reactive Protein; Cholelithiasis; Clofibrate; Creatine; Female; Gastrectomy; Humans; Hypolipidemic Agents; Incidence; Kidney Calculi; Male; Metabolic Clearance Rate; Middle Aged; Ultrasonography

1999
Effect of bezafibrate and clofibrate on the heme-iron geometry of ferrous nitrosylated heme-human serum albumin: an EPR study.
    Journal of inorganic biochemistry, 2001, Volume: 84, Issue:3-4

    Topics: Bezafibrate; Clofibrate; Electron Spin Resonance Spectroscopy; Heme; Humans; Hypolipidemic Agents; Molecular Structure; Protein Binding; Protein Structure, Quaternary; Protein Structure, Tertiary; Serum Albumin

2001
Cholesterol-lowering drugs. Some drugs with demonstrated efficacy but different benefits in primary and secondary prevention.
    Prescrire international, 1999, Volume: 8, Issue:42

    Topics: Anticholesteremic Agents; Bezafibrate; Cholestyramine Resin; Clinical Trials as Topic; Clofibrate; Female; Gemfibrozil; Humans; Hypercholesterolemia; Lovastatin; Male; Myocardial Infarction; Pravastatin; Treatment Outcome

1999
Cell-specific toxicity of fibrates in human embryonal rhabdomyosarcoma cells.
    Naunyn-Schmiedeberg's archives of pharmacology, 2003, Volume: 367, Issue:3

    Topics: Bezafibrate; Clofibrate; Clofibric Acid; Disease Models, Animal; Drug Synergism; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hypolipidemic Agents; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; Rhabdomyosarcoma, Embryonal; RNA, Messenger; Simvastatin; Time Factors; Transcription Factors; Tumor Cells, Cultured

2003
The inhibition of the human cholesterol 7alpha-hydroxylase gene (CYP7A1) promoter by fibrates in cultured cells is mediated via the liver x receptor alpha and peroxisome proliferator-activated receptor alpha heterodimer.
    Nucleic acids research, 2004, Volume: 32, Issue:3

    Topics: Acids, Acyclic; Animals; Bezafibrate; Binding Sites; Cell Line, Tumor; Cells, Cultured; Cholesterol 7-alpha-Hydroxylase; Clofibrate; Dimerization; DNA-Binding Proteins; Gemfibrozil; Gene Expression Regulation; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Humans; Hydroxycholesterols; Ligands; Liver X Receptors; Nuclear Proteins; Orphan Nuclear Receptors; Promoter Regions, Genetic; Pyrimidines; Rats; Receptors, Cytoplasmic and Nuclear; Repetitive Sequences, Nucleic Acid; Response Elements; Transcription Factors

2004
PPARalpha agonists stimulate progastrin production in human colorectal carcinoma cells.
    Regulatory peptides, 2004, Aug-15, Volume: 120, Issue:1-3

    Topics: Bezafibrate; Cell Proliferation; Clofibrate; Clofibric Acid; Colorectal Neoplasms; Fenofibrate; Fibric Acids; Gastrins; Gemfibrozil; Humans; Hypolipidemic Agents; Ligands; Peroxisome Proliferator-Activated Receptors; Protein Precursors; Pyrimidines; Radioimmunoassay; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Vasodilator Agents

2004
Synthesis of highly water-soluble fibrate derivatives via BGLation.
    Bioorganic & medicinal chemistry letters, 2012, Oct-15, Volume: 22, Issue:20

    Topics: Animals; Bezafibrate; Clofibrate; Fenofibrate; Hypolipidemic Agents; Male; Rats; Rats, Sprague-Dawley; Solubility; Triglycerides; Water

2012
Opposing Effects of PPARα Agonism and Antagonism on Refractive Development and Form Deprivation Myopia in Guinea Pigs.
    Investigative ophthalmology & visual science, 2018, 12-03, Volume: 59, Issue:15

    Topics: Animals; Apolipoprotein A-II; Bezafibrate; Biometry; Blotting, Western; Butyrates; Clofibrate; Collagen Type I; Disease Models, Animal; Electroretinography; Fluorescent Antibody Technique, Indirect; Guinea Pigs; Intraocular Pressure; Malate Dehydrogenase; Myopia; Oxazoles; Phenylurea Compounds; PPAR alpha; Refraction, Ocular; Sensory Deprivation; Tyrosine

2018
Effects of clofibrate and KH176 on life span and motor function in mitochondrial complex I-deficient mice.
    Biochimica et biophysica acta. Molecular basis of disease, 2020, 06-01, Volume: 1866, Issue:6

    Topics: Adenosine Triphosphate; Animals; Bezafibrate; Chromans; Clofibrate; Electron Transport Complex I; Fatty Acids; Humans; Leigh Disease; Longevity; Mice; Mice, Knockout; Mitochondria; Mitochondrial Diseases; Motor Activity; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptors

2020