clofibrate and beta-naphthoflavone

clofibrate has been researched along with beta-naphthoflavone in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19906 (30.00)18.7374
1990's9 (45.00)18.2507
2000's5 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Blaauboer, BJ; de Kruif, CA; Falke, HE; Noordhoek, J; van Iersel, AA; Wortelboer, HM1
Bui, QD; Weisz, J; Wrighton, SA1
Gibson, GG; MacNicoll, AD; Sutcliffe, FA1
Bawden, MJ; Hansen, AJ; May, BK; Srivastava, G1
Bachmann, KA; Jahn, D; Schwartz, J; Yang, C1
Buffoni, F; Cintelli, A; Ignesti, G; Perretti, M1
Boobis, AR; Davies, DS; Elcombe, CR; Foster, JR; Hayward, C; Lock, EA; McQuade, J; Robson, RT; Sesardic, D1
Heinemeyer, G; Hildebrandt, AG; Nau, H; Roots, I1
Balfour, C; Dunbar, D; Halpert, J; Kaminsky, LS; Miller, NE; Morgan, ET1
Blaauboer, BJ; Luijckx, NB; Mennes, WC; Noordhoek, J; Wortelboer, HM1
Buhler, DR; Henderson, MC; Miranda, CL; Williams, DE1
Alvinerie, M; Coulet, M; Dacasto, M; Eeckhoutte, C; Galtier, P; Larrieu, G; Macé, K; Pfeifer, AM; Sutra, JF1
Amacher, DE; Schomaker, SJ1
Carmichael, N; Debruyne, E; Lassere, D; Nicod, L; Richert, L; Viollon-Abadie, C1
Gibson, GG; Goldfarb, PS; Gray, TJ; Ogg, MS; Tarbit, M; Williams, JM1
Kagayama, A; Mitani, Y; Niwa, T; Shiraga, T; Terakawa, M; Tokuma, Y1
Amato, G; Gervasi, PG; Giorgi, M; Longo, V; Marini, S; Mazzaccaro, A1
Alton, K; Chu, I; Goodsaid, FM; Gu, C; Kishnani, NS; Li, Z; Mandakas, G; Montgomery, D; Norton, L; Palamanda, JR; Rosenblum, IY; Smith, R; Soares, T; You, X1
Chu, I; Gu, YZ; Kumari, P; Lin, X; Mandakas, G; Palamanda, J; Smith, RJ; Snyder, RD; Soares, A; Wang, EJ1

Reviews

1 review(s) available for clofibrate and beta-naphthoflavone

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000

Other Studies

19 other study(ies) available for clofibrate and beta-naphthoflavone

ArticleYear
Comparison of cytochrome P450 isoenzyme profiles in rat liver and hepatocyte cultures. The effects of model inducers on apoproteins and biotransformation activities.
    Biochemical pharmacology, 1991, Jul-05, Volume: 42, Issue:2

    Topics: Animals; Apoproteins; Aryl Hydrocarbon Hydroxylases; Benzoflavones; beta-Naphthoflavone; Biotransformation; Blotting, Western; Cells, Cultured; Clofibrate; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Dexamethasone; Enzyme Induction; Isoenzymes; Isoniazid; Liver; Male; Microsomes, Liver; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases

1991
Hepatic catecholestrogen synthases: differential effect of sex, inducers of cytochromes P-450 and of antibody to the glucocorticoid inducible cytochrome P-450 on NADPH-dependent estrogen-2-hydroxylase and on organic hydroperoxide-dependent estrogen-2/4-hy
    The Journal of steroid biochemistry and molecular biology, 1990, Volume: 37, Issue:2

    Topics: Animals; Antibodies; Benzoflavones; beta-Naphthoflavone; Clofibrate; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Estradiol; Estrogens, Catechol; Female; Isoniazid; Kinetics; Male; Microsomes, Liver; NADP; Phenobarbital; Rats; Rats, Inbred Strains; Sex Factors

1990
Hepatic microsomal warfarin metabolism in warfarin-resistant and susceptible mouse strains: influence of pretreatment with cytochrome P-450 inducers.
    Chemico-biological interactions, 1990, Volume: 75, Issue:2

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Clofibrate; Cytochrome P-450 Enzyme System; Drug Resistance; Enzyme Induction; Female; Male; Mice; Microsomes, Liver; Phenobarbital; Sex Factors; Species Specificity; Stereoisomerism; Warfarin

1990
Heme may not be a positive regulator of cytochrome-P450 gene expression.
    European journal of biochemistry, 1989, Jan-02, Volume: 178, Issue:3

    Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Benzoflavones; beta-Naphthoflavone; Clofibrate; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Gene Expression Regulation; Genes; Heme; Humans; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains; Reference Values; RNA, Messenger; Transcription, Genetic

1989
The use of single sample clearance estimates to probe hepatic drug metabolism in rats. II.
    Xenobiotica; the fate of foreign compounds in biological systems, 1988, Volume: 18, Issue:2

    Topics: Animals; Antipyrine; Benzoflavones; beta-Naphthoflavone; Clofibrate; Drug Interactions; Liver; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Phenobarbital; Rats; Rats, Inbred Strains; Safrole; Theophylline; Valproic Acid; Warfarin

1988
Induction and quail liver diamine oxidase (histaminase). Part II: Different responses to the inducers.
    Agents and actions, 1988, Volume: 25, Issue:1-2

    Topics: Amine Oxidase (Copper-Containing); Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Clofibrate; Enzyme Induction; Histamine; In Vitro Techniques; Microsomes, Liver; Phenobarbital; Putrescine; Quail; Substrate Specificity

1988
Immunocytochemical localization of cytochrome P-450 in hepatic and extra-hepatic tissues of the rat with a monoclonal antibody against cytochrome P-450 c.
    Biochemical pharmacology, 1986, Dec-15, Volume: 35, Issue:24

    Topics: Adrenal Glands; Animals; Antibodies, Monoclonal; Benzoflavones; beta-Naphthoflavone; Clofibrate; Cytochrome P-450 Enzyme System; Enzyme Induction; Histocytochemistry; Immunoenzyme Techniques; Intestine, Small; Isoenzymes; Kidney; Liver; Lung; Male; Mice; Olfactory Mucosa; Phenobarbital; Rats; Rats, Inbred Strains; Testis

1986
Oxidation and glucuronidation of valproic acid in male rats--influence of phenobarbital, 3-methylcholanthrene, beta-naphthoflavone and clofibrate.
    Biochemical pharmacology, 1985, Jan-01, Volume: 34, Issue:1

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Clofibrate; Enzyme Induction; Flavonoids; Glucuronates; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Oxidation-Reduction; Phenobarbital; Rats; Rats, Inbred Strains; Valproic Acid

1985
Isozyme selectivity of the inhibition of rat liver cytochromes P-450 by chloramphenicol in vivo.
    Molecular pharmacology, 1985, Volume: 28, Issue:3

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Chloramphenicol; Clofibrate; Cytochrome P-450 Enzyme Inhibitors; Isoenzymes; Lauric Acids; Liver; Male; Mixed Function Oxygenases; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains; Safrole; Steroid 16-alpha-Hydroxylase; Substrate Specificity; Testosterone; Warfarin

1985
Differences in the effects of model inducers of cytochrome P450 on the biotransformation of scoparone in rat and hamster liver.
    Archives of toxicology, 1993, Volume: 67, Issue:2

    Topics: Animals; Antihypertensive Agents; Benzoflavones; beta-Naphthoflavone; Biotransformation; Clofibrate; Coumarins; Cricetinae; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Guinea Pigs; Isoniazid; Liver; Male; Mesocricetus; Microsomes, Liver; Phenobarbital; Rats; Rats, Wistar; Species Specificity

1993
In vitro metabolism of 7,12-dimethylbenz[a]anthracene by rainbow trout liver microsomes and trout P450 isoforms.
    Toxicology and applied pharmacology, 1997, Volume: 142, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; beta-Naphthoflavone; Biotransformation; Clofibrate; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Dexamethasone; DNA Adducts; Drug Synergism; Ellipticines; Enzyme Induction; Enzyme Inhibitors; Isoenzymes; Microsomes, Liver; Oncorhynchus mykiss; Proteins; Safrole

1997
Identification of human and rabbit cytochromes P450 1A2 as major isoforms involved in thiabendazole 5-hydroxylation.
    Fundamental & clinical pharmacology, 1998, Volume: 12, Issue:2

    Topics: Animals; Anticholesteremic Agents; beta-Naphthoflavone; Bronchi; Cells, Cultured; Clofibrate; Cytochrome P-450 CYP1A2; Enzyme Induction; Enzyme Inhibitors; Epithelial Cells; Humans; Hydroxylation; Isoenzymes; Liver; Male; Mixed Function Oxygenases; Rabbits; Species Specificity; Thiabendazole

1998
Ethylmorphine N-demethylase activity as a marker for cytochrome P450 CYP3A activity in rat hepatic microsomes.
    Toxicology letters, 1998, Jan-31, Volume: 94, Issue:2

    Topics: Animals; Antibodies; Aryl Hydrocarbon Hydroxylases; beta-Naphthoflavone; Biomarkers; Clofibrate; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Enzyme Inhibitors; Ethylmorphine-N-Demethylase; Female; Isoniazid; Male; Microsomes, Liver; Oxidoreductases, N-Demethylating; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Sex Factors

1998
Phenobarbital, beta-naphthoflavone, clofibrate, and pregnenolone-16alpha-carbonitrile do not affect hepatic thyroid hormone UDP-glucuronosyl transferase activity, and thyroid gland function in mice.
    Toxicology and applied pharmacology, 1999, Feb-15, Volume: 155, Issue:1

    Topics: Animals; beta-Naphthoflavone; Clofibrate; Cytochrome P-450 Enzyme System; Enzyme Induction; Glucuronosyltransferase; Liver; Male; Mice; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Sprague-Dawley; Thyroid Gland; Thyroid Hormones

1999
A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro.
    Xenobiotica; the fate of foreign compounds in biological systems, 1999, Volume: 29, Issue:3

    Topics: Alkaline Phosphatase; beta-Naphthoflavone; Caffeine; Carbamazepine; Carcinoma, Hepatocellular; Clofibrate; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Gene Expression Regulation; Genes, Reporter; Glucocorticoids; Hormone Antagonists; Humans; Isoniazid; Mifepristone; Mixed Function Oxygenases; Phenobarbital; Phenylbutazone; Phenytoin; Receptors, Glucocorticoid; Recombinant Proteins; Rifampin; Tumor Cells, Cultured; Xenobiotics

1999
Stereoselective metabolism of cibenzoline, an antiarrhythmic drug, by human and rat liver microsomes: possible involvement of CYP2D and CYP3A.
    Drug metabolism and disposition: the biological fate of chemicals, 2000, Volume: 28, Issue:9

    Topics: Animals; Anti-Arrhythmia Agents; Aryl Hydrocarbon Hydroxylases; beta-Naphthoflavone; Cell Line; Chromatography, High Pressure Liquid; Clofibrate; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Female; Humans; Imidazoles; Ketoconazole; Kinetics; Male; Microsomes; Microsomes, Liver; Oxidoreductases, N-Demethylating; Phenobarbital; Quinidine; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Sex Factors; Stereoisomerism

2000
Cytochrome P450-dependent monooxygenase activities and their inducibility by classic P450 inducers in the liver, kidney, and nasal mucosa of male adult ring-necked pheasants.
    Toxicology and applied pharmacology, 2000, Sep-15, Volume: 167, Issue:3

    Topics: Acetone; Animals; beta-Naphthoflavone; Birds; Clofibrate; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Kidney; Microsomes, Liver; Nasal Mucosa; Phenobarbital

2000
Assessment of temporal biochemical and gene transcription changes in rat liver cytochrome P450: utility of real-time quantitative RT-PCR.
    Pharmaceutical research, 2003, Volume: 20, Issue:9

    Topics: Animals; beta-Naphthoflavone; Blotting, Western; Clofibrate; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Enzyme Inhibitors; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic

2003
Temporal evaluation of CYP mRNA in mice administered with prototypical P450 inducers: comparison with conventional protein/enzyme methods.
    Drug and chemical toxicology, 2008, Volume: 31, Issue:4

    Topics: Animals; beta-Naphthoflavone; Clofibrate; Cytochrome P-450 Enzyme System; Dexamethasone; Drug Evaluation, Preclinical; Enzyme Induction; Feasibility Studies; Isoenzymes; Liver; Male; Mice; Phenobarbital; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors

2008