clofibrate has been researched along with arachidonic acid in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (45.45) | 18.7374 |
| 1990's | 7 (31.82) | 18.2507 |
| 2000's | 5 (22.73) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bezard, J; Blond, JP; Christiansen, EN; Mimouni, V; Poisson, JP; Ulmann, L | 1 |
| Feller, DR; Kim, SU; Newman, HA; Romstedt, KJ; Witiak, DT | 1 |
| Doig, MV; Gibson, GG; Lewis, DF; Sharma, RK | 1 |
| Bergseth, S; Bremer, J; Christiansen, EN | 1 |
| Feller, DR; Kim, SK; Newman, HA; Romstedt, K; Witiak, DT | 1 |
| Anwer, K; Gabis, J; Gojer, C; Romstedt, K | 1 |
| Capdevila, J; Estabrook, RW; Falck, JR; Kim, YR; Manna, S; Martin-Wixtrom, C | 1 |
| Feller, DR; Fertel, RH; Newman, HA; Witiak, DT | 1 |
| Gangolli, SD; Gray, TJ; Hodder, KD; Lake, BG; Stubberfield, CR; Tredger, JM; Williams, R | 1 |
| Artús, JJ; Bruseghini, L; Freixes, J; Ribalta, JM; Roma, E; Salvador, L; Vilageliu, J | 1 |
| Bruseghini, L; Freixes, J; Vilageliu, J | 1 |
| Abraham, NG; Lin, F; Schwartzman, ML | 1 |
| Frohlich, B; Ma, YH; Markham, B; Roman, RJ | 1 |
| Borhan, B; Hammock, BD; Moghaddam, M; Motoba, K; Pinot, F | 1 |
| Miller, CW; Ntambi, JM | 1 |
| Simpson, AE | 1 |
| Aversa, E; Bonazzi, A; Mastyugin, V; Mieyal, P; Schwartzman, ML; Vafaes, C | 1 |
| Diot, C; Douaire, M; Lefevre, P; Plumelet, C; Tripon, E | 1 |
| Kasyu, H; Kikuta, Y; Kusunose, E; Kusunose, M | 1 |
| Choy, PC; Dembinski, T; Hatch, GM; Jiang, YJ; Kroeger, EA; Mymin, D | 1 |
| DuTeaux, SB; Fairbairn, EA; Hammock, BD; Jelks, K; Miller, MG; Morisseau, C; Newman, JW | 1 |
| Ahokas, JT; Grzemski, FA; Panagiotopoulos, S; Tian, Q | 1 |
1 review(s) available for clofibrate and arachidonic acid
| Article | Year |
|---|---|
The cytochrome P450 4 (CYP4) family.
Topics: Animals; Arachidonic Acid; Clofibrate; Cytochrome P-450 Enzyme System; Enzyme Induction; Humans; Isoenzymes; Kidney; Lipid Metabolism; Liver; Microbodies | 1997 |
21 other study(ies) available for clofibrate and arachidonic acid
| Article | Year |
|---|---|
Elongation and desaturation of arachidonic and eicosapentaenoic acids in rat liver. Effect of clofibrate feeding.
Topics: Animals; Arachidonic Acid; Clofibrate; Eicosapentaenoic Acid; Liver; Male; Microsomes, Liver; Mitochondria, Liver; Rats | 1991 |
Potent antiplatelet effects of cyclic clofibric acid (CPIB) analogs on human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Benzopyrans; Chromans; Clofibrate; Clofibric Acid; Epinephrine; Humans; Malondialdehyde; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Thrombin | 1989 |
Role of hepatic and renal cytochrome P-450 IVA1 in the metabolism of lipid substrates.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure Liquid; Clofibrate; Cytochrome P-450 Enzyme System; Gas Chromatography-Mass Spectrometry; Hydroxylation; Isoenzymes; Kidney; Leukotriene B4; Liver; Male; Models, Molecular; Rats; Rats, Inbred Strains | 1989 |
The effect of feeding fish oils, vegetable oils and clofibrate on the ketogenesis from long chain fatty acids in hepatocytes.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Body Weight; Carbon Radioisotopes; Clofibrate; Fatty Acids; Fatty Acids, Nonesterified; Fish Oils; In Vitro Techniques; Ketones; Kinetics; Male; Oils; Palmitic Acid; Palmitic Acids; Rats; Structure-Activity Relationship | 1986 |
Comparative antiaggregatory activity in human platelets of a benzopyranone aci-reductone, clofibric acid, and a 2,3-dihydrobenzofuran analogue.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Arachidonic Acid; Arachidonic Acids; Benzofurans; Blood Platelets; Clofibrate; Clofibric Acid; Coumarins; Humans; In Vitro Techniques; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Serotonin; Structure-Activity Relationship | 1986 |
Beclobrinic acid--a new hypolipidemic agent--inhibits in vitro human platelet activation by blocking prostaglandin synthesis.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Arachidonic Acid; Arachidonic Acids; Benzhydryl Compounds; Blood Platelets; Clofibrate; Clofibric Acid; Humans; Hypolipidemic Agents; In Vitro Techniques; Malondialdehyde; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Serotonin | 1985 |
Influence of a fibric acid type of hypolipidemic agent on the oxidative metabolism of arachidonic acid by liver microsomal cytochrome P-450.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Benzphetamine; Chromatography, High Pressure Liquid; Clofibrate; Clofibric Acid; Cytochrome P-450 Enzyme System; Fatty Acids, Unsaturated; Fibric Acids; Gas Chromatography-Mass Spectrometry; Hydroxyeicosatetraenoic Acids; Hypolipidemic Agents; Lauric Acids; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1985 |
Potentiating effects of clofibrate on prostaglandin-dependent and -independent pathways of human platelet activation: evidence for involvement of cyclic AMP.
Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Clofibrate; Cyclic AMP; Humans; In Vitro Techniques; Oxygen Consumption; Platelet Aggregation; Prostaglandins; Time Factors; Type C Phospholipases | 1982 |
The effect of peroxisome proliferators on the metabolism and spectral interaction of endogenous substrates of cytochrome P-450 in rat hepatic microsomes.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Clofibrate; Clofibric Acid; Cytochrome P-450 Enzyme System; Diethylhexyl Phthalate; Hydroxylation; Linoleic Acid; Linoleic Acids; Male; Microbodies; Microsomes, Liver; Phthalic Acids; Rats; Rats, Inbred Strains; Testosterone | 1984 |
Synthesis and pharmacological evaluation of N'-morpholinomethylurea derivatives with platelet antiaggregant activity.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Chemical Phenomena; Chemistry; Clofibrate; Clofibric Acid; Humans; Hypolipidemic Agents; In Vitro Techniques; Lethal Dose 50; Platelet Aggregation; Rats; Rats, Inbred Strains | 1981 |
Platelet antiaggregant activity of plafibride ex vivo in rat, dog and rabbit.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Clofibrate; Clofibric Acid; Collagen; Dogs; Epinephrine; Female; In Vitro Techniques; Male; Platelet Aggregation; Rabbits; Rats; Rats, Inbred Strains; Species Specificity | 1981 |
Arachidonic acid omega-hydroxylation and cytochrome P450 4A expression in the rat kidney.
Topics: Aging; Animals; Arachidonic Acid; Clofibrate; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Female; Gene Expression; Gestational Age; Hydroxylation; Kidney Cortex; Male; Microsomes; Mixed Function Oxygenases; Rats; Rats, Sprague-Dawley | 1995 |
Clofibrate prevents the development of hypertension in Dahl salt-sensitive rats.
Topics: Animals; Arachidonic Acid; Blood Pressure; Clofibrate; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Drug Resistance; Female; Hydroxyeicosatetraenoic Acids; Hypertension; Lipids; Liver; Mixed Function Oxygenases; Rats; Rats, Inbred Strains; Rats, Mutant Strains; Sodium Chloride | 1993 |
Novel metabolic pathways for linoleic and arachidonic acid metabolism.
Topics: Animals; Arachidonic Acid; Clofibrate; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme Inhibitors; Epoxide Hydrolases; Epoxy Compounds; Linoleic Acid; Linoleic Acids; Male; Mice; Microsomes, Liver; Oxidation-Reduction; Phenobarbital; Trichloroepoxypropane | 1996 |
Peroxisome proliferators induce mouse liver stearoyl-CoA desaturase 1 gene expression.
Topics: Animals; Arachidonic Acid; Base Sequence; Chloramphenicol O-Acetyltransferase; Clofibrate; Cycloheximide; Fatty Acids, Unsaturated; Gemfibrozil; Gene Expression Regulation, Enzymologic; Liver; Mice; Mice, Inbred BALB C; Microbodies; Molecular Sequence Data; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Stearoyl-CoA Desaturase; Transcription Factors; Transcription, Genetic | 1996 |
Hypoxia-induced production of 12-hydroxyeicosanoids in the corneal epithelium: involvement of a cytochrome P-4504B1 isoform.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonic Acid; Aryl Hydrocarbon Hydroxylases; Base Sequence; Cell Hypoxia; Clofibrate; Cloning, Molecular; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; DNA, Complementary; Epithelium, Corneal; Female; Isoenzymes; Lung; Male; Mixed Function Oxygenases; Molecular Sequence Data; Organ Culture Techniques; Phenobarbital; Polymerase Chain Reaction; Rabbits; RNA, Messenger; Sequence Alignment; Sequence Homology, Nucleic Acid; Stereoisomerism; Transcription, Genetic | 1999 |
Effects of polyunsaturated fatty acids and clofibrate on chicken stearoyl-coA desaturase 1 gene expression.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Base Sequence; Chickens; Clofibrate; Fatty Acids, Unsaturated; Gene Expression Regulation, Enzymologic; Genes, Reporter; Luciferases; Molecular Sequence Data; Promoter Regions, Genetic; Stearoyl-CoA Desaturase; TATA Box; Transfection; Tumor Cells, Cultured | 2001 |
Expression and catalytic activity of mouse leukotriene B4 omega-hydroxylase, CYP4F14.
Topics: 5' Untranslated Regions; Alternative Splicing; Amino Acid Sequence; Animals; Arachidonic Acid; Base Sequence; Blotting, Northern; Brain; Catalysis; Clofibrate; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; DNA, Complementary; Exons; Hydroxyeicosatetraenoic Acids; Introns; Laurates; Leukotriene B4; Lipoxins; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microsomes, Liver; Mixed Function Oxygenases; Models, Genetic; Molecular Sequence Data; Prostaglandins A; Rats; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid; Substrate Specificity; Tissue Distribution; Transcription, Genetic; Transfection | 2000 |
Modulation of cytosolic phospholipase A(2) by PPAR activators in human preadipocytes.
Topics: Acyl-CoA Oxidase; Adipocytes; Arachidonic Acid; Calcimycin; Clofibrate; Cyclooxygenase 2; Enzyme Activation; Humans; Hypolipidemic Agents; Ionophores; Isoenzymes; Liposarcoma; Membrane Proteins; Oxidoreductases; Phospholipases A; Prostaglandin-Endoperoxide Synthases; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factors; Tumor Cells, Cultured; Up-Regulation | 2001 |
Epoxide hydrolases in the rat epididymis: possible roles in xenobiotic and endogenous fatty acid metabolism.
Topics: Animals; Arachidonic Acid; Clofibrate; Enzyme Activation; Epididymis; Epoxide Hydrolases; Epoxy Compounds; Male; Microsomes; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Spermatozoa; Xenobiotics | 2004 |
Peroxisome proliferator-activated receptor alpha agonist, clofibrate, has profound influence on myocardial fatty acid composition.
Topics: Animals; Antioxidants; Arachidonic Acid; Catalase; Clofibrate; Docosahexaenoic Acids; Fatty Acids, Omega-6; Fatty Acids, Unsaturated; Glutathione; Heart; Hypolipidemic Agents; Linoleic Acid; Lipid Peroxidation; Male; Myocardium; PPAR alpha; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances | 2006 |