Compounds > clofibrate

clofibrate and aminopyrine

clofibrate has been researched along with aminopyrine in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Dayan, J; Deguingand, S; Truzman, C1
McIntosh, DA; Topham, JC1
Feller, DR; Lewis, NJ; Witiak, DT1

Other Studies

6 other study(ies) available for clofibrate and aminopyrine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Study of the mutagenic activity of 6 hepatotoxic pharmaceutical drugs in the Salmonella typhimurium microsome test, and the HGPRT and Na+/K+ ATPase system in cultured mammalian cells.
    Mutation research, 1985, Volume: 157, Issue:1

    Topics: Aminopyrine; Animals; Biotransformation; Cell Line; Clofibrate; Cricetinae; Cricetulus; Drug Resistance; Glycolates; Hypoxanthine Phosphoribosyltransferase; Liver; Lung; Microsomes, Liver; Mutagenicity Tests; Mutagens; Mutation; Nitrofurans; Nitroquinolines; Ouabain; Oxamniquine; Perhexiline; Rats; Rats, Inbred Strains; Salmonella typhimurium; Sodium-Potassium-Exchanging ATPase; Thioguanine; Ticrynafen

1985
A comparison of mouse and rat liver enzymes and their response to treatment with various compounds.
    Biochemical pharmacology, 1972, Apr-01, Volume: 21, Issue:7

    Topics: Aminopyrine; Animals; Carbon Tetrachloride; Chlorpromazine; Clofibrate; Cytochromes; DDT; Germ-Free Life; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Griseofulvin; L-Lactate Dehydrogenase; Liver; Mice; NAD; NADP; Organ Size; Oxidoreductases; Phenobarbital; Phosphogluconate Dehydrogenase; Rats; Species Specificity

1972
Influence of clofibrate (ethyl-4-chlorophenoxyisobutyrate) on hepatic drug metabolism in male rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1974, Volume: 145, Issue:1

    Topics: Age Factors; Aminopyrine; Aniline Compounds; Animals; Clofibrate; Cytochrome P-450 Enzyme System; Glucosephosphate Dehydrogenase; Hexobarbital; Hydroxylation; Liver; Male; Microsomes, Liver; Morphine; Pentobarbital; Proteins; Rats; Sleep; Zoxazolamine

1974