clofibrate and allopurinol

clofibrate has been researched along with allopurinol in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19907 (36.84)18.7374
1990's1 (5.26)18.2507
2000's1 (5.26)29.6817
2010's10 (52.63)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Graham, GG; Pond, SM; Sudlow, G; Wade, DN1
Drayer, DE; Reidenberg, MM1
Griffin, JP; Parkins, A; Williams, JR1
Sellers, E; Weser, JK1
Fabre, J; Herrera, A; Perrin, L; Petitpierre, B; Rudhardt, M1
Frahm, H; von Torklus, D; Wilke, H; Zsernaviezky, J1
Amidi, M1
Fujii, J; Islam, KN; Kawata, S; Kayanoki, Y; Matsuzawa, Y; Suzuki, K; Taniguchi, N1

Reviews

2 review(s) available for clofibrate and allopurinol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drug interactions with coumarin anticoagulants. 2.
    The New England journal of medicine, 1971, Sep-02, Volume: 285, Issue:10

    Topics: Allopurinol; Anabolic Agents; Animals; Anti-Bacterial Agents; Anticoagulants; Barbiturates; Chloral Hydrate; Chloramphenicol; Cholestyramine Resin; Clofibrate; Contraceptives, Oral; Coumarins; Dextrothyroxine; Diuretics; Drug Antagonism; Drug Synergism; Ethacrynic Acid; Ethanol; Glucagon; Glucocorticoids; Glutethimide; Humans; Oxyphenbutazone; Phenylbutazone; Quinidine; Quinine; Quinolines; Salicylates; Sulfinpyrazone; Sulfonamides; Thyroid Hormones; Tolbutamide

1971

Other Studies

17 other study(ies) available for clofibrate and allopurinol

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
The effects of allopurinol and clofibrate on the elimination of coumarin anticoagulants in man.
    Australian and New Zealand journal of medicine, 1975, Volume: 5, Issue:4

    Topics: Adult; Allopurinol; Biological Availability; Blood Proteins; Butyrates; Clofibrate; Dicumarol; Half-Life; Humans; Male; Protein Binding; Warfarin

1975
Drug metabolism and active drug metabolites in renal failure.
    Journal of dialysis, 1977, Volume: 1, Issue:4

    Topics: Allopurinol; Biotransformation; Clofibrate; Dose-Response Relationship, Drug; Humans; Kidney Failure, Chronic; Meperidine; Procainamide; Sulfonamides

1977
Effect of concomitantly administered drugs on the control of long term anticoagulant therapy.
    The Quarterly journal of medicine, 1976, Volume: 45, Issue:177

    Topics: Allopurinol; Anabolic Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Antidepressive Agents, Tricyclic; Barbiturates; Clofibrate; Digoxin; Diuretics; Drug Administration Schedule; Drug Interactions; Ethanol; Female; Humans; Hypoglycemic Agents; Male; Phenothiazines; Warfarin

1976
Behaviour of chlorpropamide in renal insufficiency and under the effect of associated drug therapy.
    International journal of clinical pharmacology, therapy and toxicology, 1972, Volume: 6, Issue:2

    Topics: Acenocoumarol; Allopurinol; Chloramphenicol; Chlorpropamide; Clofibrate; Glomerular Filtration Rate; Glomerulonephritis; Half-Life; Humans; Kidney; Kidney Diseases; Probenecid; Pyelonephritis

1972
[Multiple aseptic bone necrosis in hyperlipidaemia, hyperuricaemia, and latent diabetes mellitus (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1974, Jul-19, Volume: 99, Issue:29

    Topics: Adult; Allopurinol; Bone Diseases; Clofibrate; Diet Therapy; Dietary Carbohydrates; Femur Head Necrosis; Humans; Humerus; Hyperlipidemias; Joint Prosthesis; Knee Joint; Lipoproteins; Male; Necrosis; Prediabetic State; Triglycerides; Uric Acid

1974
Type IV hyperlipoproteinemia in a consanguinous family.
    Circulation, 1972, Volume: 45, Issue:5

    Topics: Adult; Aged; Allopurinol; Clofibrate; Consanguinity; Dietary Carbohydrates; Female; Glucose Tolerance Test; Gout; Humans; Hyperlipidemias; Lipoproteins; Male; Middle Aged; Myocardial Infarction; Pedigree; Triglycerides; Xanthomatosis

1972
The protective role of glutathione peroxidase in apoptosis induced by reactive oxygen species.
    Journal of biochemistry, 1996, Volume: 119, Issue:4

    Topics: Animals; Antioxidants; Apoptosis; Benzene Derivatives; Catalase; Cattle; Cell Line; Cell Survival; Clofibrate; Glucose Oxidase; Glutathione Peroxidase; Hydrogen Peroxide; Oxidative Stress; Peroxides; Reactive Oxygen Species; Selenious Acid; Selenium; Selenium Compounds; Superoxide Dismutase; Superoxides; Vitamin K; Xanthine Oxidase

1996