clofibrate has been researched along with 25-hydroxycholesterol in 2 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (100.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Guan, JZ; Matsui, J; Murakami, H; Suda, T; Tamasawa, N; Yamato, K | 1 |
Agellon, LB; Gbaguidi, GF | 1 |
2 other study(ies) available for clofibrate and 25-hydroxycholesterol
Article | Year |
---|---|
Clofibrate, a peroxisome-proliferator, enhances reverse cholesterol transport through cytochrome P450 activation and oxysterol generation.
Topics: Animals; Anticholesteremic Agents; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Biological Transport; Blotting, Northern; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Clofibrate; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA-Binding Proteins; Drug Therapy, Combination; Hydroxycholesterols; Ketoconazole; Lipid Metabolism; Lipoproteins; Liver X Receptors; Male; Microsomes, Liver; Orphan Nuclear Receptors; Peroxisome Proliferators; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; RNA; RNA, Messenger; Steroids; Transcription Factors; Up-Regulation | 2003 |
The inhibition of the human cholesterol 7alpha-hydroxylase gene (CYP7A1) promoter by fibrates in cultured cells is mediated via the liver x receptor alpha and peroxisome proliferator-activated receptor alpha heterodimer.
Topics: Acids, Acyclic; Animals; Bezafibrate; Binding Sites; Cell Line, Tumor; Cells, Cultured; Cholesterol 7-alpha-Hydroxylase; Clofibrate; Dimerization; DNA-Binding Proteins; Gemfibrozil; Gene Expression Regulation; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Humans; Hydroxycholesterols; Ligands; Liver X Receptors; Nuclear Proteins; Orphan Nuclear Receptors; Promoter Regions, Genetic; Pyrimidines; Rats; Receptors, Cytoplasmic and Nuclear; Repetitive Sequences, Nucleic Acid; Response Elements; Transcription Factors | 2004 |