clofibrate has been researched along with 2-acetylaminofluorene in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (33.33) | 18.7374 |
| 1990's | 5 (41.67) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Goto, M; Mochizuki, Y; Tsukada, H | 1 |
| Aoki, T; Ito, N; Mutai, M; Tatematsu, M; Wada, S | 1 |
| Rajan, A; Rao, MS; Reddy, JK; Subbarao, V; Yeldandi, AV | 1 |
| Furukawa, K; Furuya, K; Numoto, S; Williams, GM | 1 |
| Furukawa, K; Gotoh, M; Mochizuki, Y; Sawada, N; Tsukada, H | 1 |
| Cattley, RC; Kato, M; Popp, JA; Teets, VJ; Voss, KS | 1 |
| Chen, L; Hardwick, JP | 1 |
| Kauffmann, HM; Schrenk, D | 1 |
| Farber, E; Nagai, MK | 1 |
| Bannasch, P; Groos, J; Kopp-Schneider, A; Schwarz, M | 1 |
| Ando, Y; Kiyosawa, N; Manabe, S; Niino, N; Watanabe, K; Yamoto, T | 1 |
12 other study(ies) available for clofibrate and 2-acetylaminofluorene
| Article | Year |
|---|---|
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
[Proceedings: Peroxisome in 2-fluorenylacetamide-induced hyperplastic liver nodule cells].
Topics: 2-Acetylaminofluorene; Animals; Clofibrate; Fluorenes; Hyperplasia; Liver Neoplasms; Microbodies; Organoids; Rats | 1975 |
Modulatory interaction between initial clofibrate treatment and subsequent administration of 2-acetylaminofluorene or sodium phenobarbital on glutathione S-transferase positive lesion development.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Clofibrate; Drug Interactions; Glutathione Transferase; Liver Neoplasms, Experimental; Male; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred F344 | 1990 |
gamma-Glutamyltranspeptidase-negative phenotypic property of preneoplastic and neoplastic liver lesions induced by ciprofibrate does not change following 2-acetylaminofluorene administration.
Topics: 2-Acetylaminofluorene; Animals; Clofibrate; Clofibric Acid; Fibric Acids; gamma-Glutamyltransferase; Liver; Liver Neoplasms; Precancerous Conditions; Rats; Rats, Inbred F344 | 1989 |
Effects of the hepatocarcinogenic peroxisome-proliferating hypolipidemic agents clofibrate and nafenopin on the rat liver cell membrane enzymes gamma-glutamyltranspeptidase and alkaline phosphatase and on the early stages of liver carcinogenesis.
Topics: 2-Acetylaminofluorene; Alkaline Phosphatase; Animals; Body Weight; Cell Division; Cell Membrane; Clofibrate; gamma-Glutamyltransferase; Histocytochemistry; Liver; Liver Neoplasms, Experimental; Male; Microbodies; Nafenopin; Organ Size; Propionates; Rats; Rats, Inbred F344 | 1984 |
Primary culture of preneoplastic hepatocytes from rats treated with 2-acetylaminofluorene and clofibrate: relationship between resistance to dimethylnitrosamine and responsiveness of peroxisomes.
Topics: 2-Acetylaminofluorene; Animals; Cells, Cultured; Clofibrate; Dimethylnitrosamine; Drug Resistance; Liver Neoplasms, Experimental; Male; Microbodies; Microscopy, Electron; Organoids; Precancerous Conditions; Rats; Rats, Inbred Strains | 1982 |
Initiator-specific promotion of hepatocarcinogenesis by WY-14,643 and clofibrate.
Topics: 2-Acetylaminofluorene; Animals; Clofibrate; Diethylnitrosamine; Liver Neoplasms, Experimental; Male; Microbodies; Pyrimidines; Rats; Rats, Inbred F344 | 1994 |
Identification of a new P450 subfamily, CYP4F1, expressed in rat hepatic tumors.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Amino Acid Sequence; Animals; Antisense Elements (Genetics); Base Sequence; Blotting, Northern; Blotting, Western; Clofibrate; Cytochrome P-450 Enzyme System; Humans; Liver Neoplasms; Male; Microsomes; Molecular Sequence Data; Multigene Family; Rats; Sequence Homology, Amino Acid | 1993 |
Sequence analysis and functional characterization of the 5'-flanking region of the rat multidrug resistance protein 2 (mrp2) gene.
Topics: 2-Acetylaminofluorene; Animals; Binding Sites; Carcinoma, Hepatocellular; Cisplatin; Clofibrate; Cloning, Molecular; Ethinyl Estradiol; Gene Expression Regulation, Neoplastic; Genes, MDR; Genes, Reporter; Phenobarbital; Rats; RNA, Messenger; Sequence Analysis, DNA; Transfection; Tumor Cells, Cultured | 1998 |
The slow induction of resistant hepatocytes during initiation of hepatocarcinogenesis by the nongenotoxic carcinogen clofibrate.
Topics: 2-Acetylaminofluorene; Adenosine Triphosphatases; Animals; Carcinogens; Cell Division; Clofibrate; Drug Resistance; gamma-Glutamyltransferase; Glutathione S-Transferase pi; Glutathione Transferase; Immunohistochemistry; Isoenzymes; Kinetics; Liver; Liver Neoplasms, Experimental; Male; Phenotype; Rats; Rats, Inbred F344 | 1999 |
Comparison of mode of action of four hepatocarcinogens: a model-based approach.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Clofibrate; Diethylnitrosamine; Female; Liver Neoplasms; Male; Models, Biological; Nitrosamines; Phenobarbital; Rats; Rats, Wistar; Sex Characteristics; Substrate Specificity | 2007 |
Scoring multiple toxicological endpoints using a toxicogenomic database.
Topics: 2-Acetylaminofluorene; Acetaminophen; Algorithms; Animals; Biomarkers; Clofibrate; Data Interpretation, Statistical; Databases, Genetic; Endpoint Determination; Gene Expression; Liver; Male; Oligonucleotide Array Sequence Analysis; Phenobarbital; Rats; Rats, Sprague-Dawley; Toxicity Tests; Toxicogenetics | 2009 |