Compounds > clofenapate
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clofenapate and pirinixic acid

clofenapate has been researched along with pirinixic acid in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (70.00)18.2507
2000's3 (30.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ashby, J; Callander, RD; Elcombe, CR; Foster, J; Galloway, SM; Hill, R; Lefevre, PA; Mackay, JM; Randall, V; Tinwell, H1
Davies, MJ; Lake, BG; Price, RJ; Rumsby, PC1
Cattley, RC; Miller, RT; Popp, JA; Shah, RS1
Beamand, JA; Charzat, C; Lake, BG; Price, RJ; Renwick, AB; Tredger, JM1
James, NH; Roberts, RA1
Bell, AR; Bell, DR; Choudhury, AI; Dickins, M; Gray, TJ; Horley, NJ; Salter, AM; Savory, R1
Bell, DR; Elcombe, CR; Gray, TJ; Horley, NJ; Plant, NJ; Savory, RL1
Armstrong, MJ; Ashby, J; Galloway, SM; Johnson, TE1
Bell, AR; Bell, DR; Chahal, S; Choudhury, AI; Roberts, RA; Salter, AM; Tomlinson, SR1
Cunninghame, ME; Lake, BG; Price, RJ; Rumsby, PC1

Other Studies

10 other study(ies) available for clofenapate and pirinixic acid

ArticleYear
Evaluation of the genetic toxicity of the peroxisome proliferator and carcinogen methyl clofenapate, including assays using Muta Mouse and Big Blue transgenic mice.
    Human & experimental toxicology, 1994, Volume: 13, Issue:11

    Topics: Animals; Bone Marrow; Carcinogens; CHO Cells; Chromosome Aberrations; Clofenapate; Cricetinae; Humans; In Vitro Techniques; Liver; Lymphocytes; Male; Mice; Mice, Transgenic; Microbodies; Micronucleus Tests; Mutagens; Pyrimidines; Rats; Species Specificity

1994
Effect of some peroxisome proliferators on transforming growth factor-beta 1 gene expression and insulin-like growth factor II/mannose-6-phosphate receptor gene expression in rat liver.
    Carcinogenesis, 1994, Volume: 15, Issue:2

    Topics: Animals; Clofenapate; Clofibric Acid; Corn Oil; Gene Expression; Liver; Male; Microbodies; Nafenopin; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 2; Transforming Growth Factor beta

1994
The peroxisome proliferations WY-14,643 and methylclofenapate induce hepatocyte ploidy alterations and ploidy-specific DNA synthesis in F344 rats.
    Toxicology and applied pharmacology, 1996, Volume: 138, Issue:2

    Topics: Animals; Bromodeoxyuridine; Cells, Cultured; Clofenapate; DNA Replication; Liver; Male; Microbodies; Organ Size; Ploidies; Pyrimidines; Rats; Rats, Inbred F344

1996
Induction of cytochrome P450 isoenzymes in cultured precision-cut rat and human liver slices.
    Xenobiotica; the fate of foreign compounds in biological systems, 1996, Volume: 26, Issue:3

    Topics: Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Clofenapate; Clofibric Acid; Culture Techniques; Cytochrome P-450 Enzyme System; Enzyme Induction; Fibric Acids; Humans; Isoenzymes; Liver; Male; Microbodies; Phenobarbital; Pyrimidines; Rats; Rats, Sprague-Dawley

1996
Species differences in response to peroxisome proliferators correlate in vitro with induction of DNA synthesis rather than suppression of apoptosis.
    Carcinogenesis, 1996, Volume: 17, Issue:8

    Topics: Animals; Apoptosis; Blood; Clofenapate; Cricetinae; Culture Media; DNA Damage; DNA Replication; Dogs; Guinea Pigs; Homeostasis; Male; Mice; Microbodies; Nafenopin; Phenobarbital; Pyrimidines; Rats; Species Specificity; Transforming Growth Factors

1996
Molecular basis of non-responsiveness to peroxisome proliferators: the guinea-pig PPARalpha is functional and mediates peroxisome proliferator-induced hypolipidaemia.
    The Biochemical journal, 1998, Jun-15, Volume: 332 ( Pt 3)

    Topics: Amino Acid Sequence; Animals; Clofenapate; Cloning, Molecular; Cricetinae; DNA, Complementary; Humans; Hypolipidemic Agents; Lipids; Liver; Mice; Mice, Inbred C57BL; Microbodies; Molecular Sequence Data; Pyrimidines; Rats; Receptors, Cytoplasmic and Nuclear; Sequence Alignment; Transcription Factors; Xenopus

1998
The peroxisome proliferators are hepatocyte mitogens in chemically-defined media: glucocorticoid-induced PPAR alpha is linked to peroxisome proliferator mitogenesis.
    Carcinogenesis, 1998, Volume: 19, Issue:5

    Topics: Animals; Clofenapate; Clofibrate; DNA Replication; Glucocorticoids; Growth Substances; Liver; Male; Microbodies; Mitogens; Pyrimidines; Rats; Receptors, Cytoplasmic and Nuclear; Sulfides; Transcription Factors

1998
The genetic toxicity of the peroxisome proliferator class of rodent hepatocarcinogen.
    Mutation research, 2000, Mar-17, Volume: 448, Issue:2

    Topics: Animals; CHO Cells; Clofenapate; Cricetinae; Diethylhexyl Phthalate; Humans; Molecular Structure; Nafenopin; Peroxisome Proliferators; Pyrimidines

2000
Species differences in peroxisome proliferation; mechanisms and relevance.
    Mutation research, 2000, Mar-17, Volume: 448, Issue:2

    Topics: Animals; Cell Line; Clofenapate; Cricetinae; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Gene Expression Regulation; Guinea Pigs; Hepatomegaly; Humans; Liver; Male; Mesocricetus; Mice; Mice, Inbred C57BL; Mixed Function Oxygenases; Peroxisome Proliferators; Peroxisomes; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Species Specificity; Transcription Factors

2000
Species differences in hepatic peroxisome proliferation, cell replication and transforming growth factor-beta1 gene expression in the rat, Syrian hamster and guinea pig.
    Mutation research, 2000, Mar-17, Volume: 448, Issue:2

    Topics: Animals; Cell Division; Clofenapate; Clofibric Acid; Cricetinae; DNA; Fibric Acids; Gene Expression; Guinea Pigs; Liver; Male; Mesocricetus; Molecular Structure; Organ Size; Peroxisome Proliferators; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 2; Species Specificity; Transforming Growth Factor beta

2000