clofazimine and isoniazid

clofazimine has been researched along with isoniazid in 66 studies

Research

Studies (66)

Timeframe	Studies, this research(%)	All Research%
pre-1990	13 (19.70)	18.7374
1990's	11 (16.67)	18.2507
2000's	10 (15.15)	29.6817
2010's	25 (37.88)	24.3611
2020's	7 (10.61)	2.80

Authors

Authors	Studies
Haritakul, R; Keller, PA; Morgan, J	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Cho, SH; Franzblau, SG; Hwang, CH; Pauli, GF; Wan, B; Warit, S	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Barry, CE; Dartois, V	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Cai, G; Cho, S; Franzblau, SG; Jaki, BU; Lee, IA; McAlpine, JB; Napolitano, JG; Pauli, GF; Suh, JW; Wang, Y; Yang, SH	1
Dufková, I; Hrabálek, A; Karabanovich, G; Klimešová, V; Němeček, J; Pávek, P; Roh, J; Smutný, T; Stolaříková, J; Vávrová, K; Vejsová, M; Vicherek, P	1
Biava, M; Cocozza, M; Consalvi, S; Poce, G	1
Boido, V; Cannas, S; Loddo, R; Molicotti, P; Novelli, F; Parapini, S; Sparatore, A; Sparatore, F; Tasso, B; Tonelli, M; Zanetti, S	1
Centárová, I; Cole, ST; Čonka, P; Hrabálek, A; Karabanovich, G; Klimešová, V; Mikušová, K; Němeček, J; Pávek, P; Pávková, I; Roh, J; Šarkan, M; Smutný, T; Stolaříková, J; Székely, R; Vávrová, K; Vejsová, M; Vocat, A; Zemanová, J	1
Carazo, A; Hrabálek, A; Karabanovich, G; Klimešová, V; Konečná, K; Němeček, J; Pávek, P; Pavliš, O; Roh, J; Stolaříková, J; Valášková, L; Vávrová, K	1
Carazo, A; Hrabálek, A; Karabanovich, G; Klimešová, V; Němeček, J; Pávek, P; Pavliš, O; Roh, J; Stolaříková, J; Sychra, P; Valášková, L; Vávrová, K; Vlčková, H	1
Bera, S; Mondal, D	1
Dušek, J; Hrabálek, A; Huszár, S; Jand'ourek, O; Karabanovich, G; Klimešová, V; Kočová Vlčková, H; Konečná, K; Konyariková, Z; Korábečný, J; Korduláková, J; Kučera, T; Mikušová, K; Pávek, P; Pávková, I; Pavliš, O; Roh, J; Savková, K; Stolaříková, J; Vávrová, K	1
Cook, GM; Dick, T; Fridianto, KT; Go, ML; Hards, K; Lam, Y; Li, M; Negatu, DA	1
Castagnolo, D; Denny, WA; Dos Santos, JL; Fernandes, GFS; Thompson, AM	1
Iyer, GG; Ramu, G	1
Clavel-Sérès, S; Cruaud, P; Dwyer, B; Goh, KS; Jeantils, V; Rastogi, N; Ross, BC	1
Dautzenberg, B; Grosset, J; Katlama, C; Mignon, A; Parrot, R; Perronne, C; Rozenbaum, W; Truffot, C	1
Dwyer, B; Grayson, L; Hoy, J; Lucas, R; Mijch, A; Sandland, M	1
Balakrishnan, A; Christian, M; Nagarajan, M; Prabhakar, R; Somasundaram, PR; Thomas, A; Tripathy, SP	1
Aoyagi, T; Toyoda, T	1
Katoch, K; Ramanathan, U; Ramu, G	1
Gharpuray, MB; Kulkarni, DS; Kulkarni, V	1
Agins, BD; Berman, DS; el-Sadr, W; Rahal, JJ; Simberkoff, MS; Spicehandler, D	1
Nash, DR; Steele, LC; Steingrube, V; Wallace, RJ	1
Baird, B; Fauci, AS; Gill, V; Grimes, G; Lane, HC; Masur, H; Tuazon, C	1
Ganapati, R; Maniar, JK; Parikh, AC; Parikh, DA	1
Banerjee, DK; Ellard, GA; Gammon, PT; Waters, MF	1
Freerksen, E; Rosenfeld, M	1
Chaudhury, S; Ghosh, S; Hazra, S; Kundu, SK	1
Ramu, G	1
Bharadwaj, VP; Desikan, KV; Ramu, G; Venkatesan, K	1
Gangadharam, PR; Reddy, MV; Srinivasan, S	1
Dautzenberg, B; Olliaro, P	1
Lüthy, R; Opravil, M; Salfinger, M; Zaugg, M	1
Carosi, GP; Dautzenberg, B; Esposito, R; Hoy, JF; L'Age, M; Micoud, M; Olliaro, P; Opravil, M; Pirotta, N; Rozenbaum, W; Ruf, B; Sassella, D	1
Daneluzzi, D; Gangadharam, PR; Nadadhur, G; O'Sullivan, JF; Reddy, VM	1
Coker, RJ; Fisher, M; Tomlinson, DR	1
Cocco, MT; Congiu, C; De Logu, A; Onnis, V; Saddi, B; Schivo, ML	1
Bulatovic, VM; Cockerill, FR; Hall, L; Roberts, GD; Rusnak, F; Uhl, JR; Wengenack, NL	1
GRUMBACH, F	1
Seung, KJ	1
Chimara, E; da Silva Telles, MA; Ferrazoli, L; Riley, LW	1
Deo, N; Gupta, UD; Venkatesan, K	1
Chu, NH; Fu, L; Li, P; Liang, BW; Lu, Y; Wang, B; Zhao, WJ; Zheng, MQ	1
Hassan, G; Kant, S; Parengal, J; Saheer, S	1
Fu, L; Jin, H; Li, P; Lu, Y; Mdluli, K; Upton, AM; Wang, B; Xu, J; Zhao, W; Zheng, M; Zhu, H	1
Chang, KC; Leung, CC; Tam, CM; Yew, WW	1
Chiang, CY; Madan, J; Meredith, SK; Nunn, AJ; Phillips, PP; Rusen, ID; Squire, SB; Torrea, G; Van Deun, A	1
Abena Foe, JL; Aït-Khaled, N; Kuaban, C; Noeske, J; Rieder, HL; Trébucq, A	1
Adamson, J; Almeida, DV; Ammerman, NC; Bester, LA; Dorasamy, A; Grosset, JH; Mgaga, Z; Moodley, C; Moodley, S; Ngcobo, B; Singh, SD; Swanson, RV	1
Chuang, YM; Dutta, NK; Hung, CF; Karakousis, PC; Rubin, H; Wu, TC	1
Blackmore, T; McNaughton, A; McNaughton, H	1
Adamson, J; Almeida, DV; Ammerman, NC; Bester, LA; Dorasamy, A; Grosset, JH; Mgaga, Z; Moodley, C; Moodley, S; Ngcobo, B; Singh, SD; Swanson, RV; Tapley, A	1
Caminero, JA; Migliori, GB; Piubello, A; Scardigli, A	1
Cao, P; Doan, TN; Emeto, TI; McBryde, ES; McCaw, JM	1
Batalha, IL; Bernut, A; Castro-Hartmann, P; Floto, RA; Kinna, S; Klapholz, C; Michel, S; Ouberai, MM; Passemar, C; Renshaw, SA; Sader, K; Schiebler, M; Welland, ME	1
Ahmad, N; Atif, M; Ghafoor, A; Iqbal, Q; Khan, S; Latif, A; Saleem, F; Wahid, A	1
Chew, R; Woods, ML	1
Anderson, R; Cholo, MC; Mashele, SA; Matjokotja, MT; Rasehlo, SSM; Steel, HC	1
Chen, X; Ding, Y; Fu, L; Guo, S; Liu, H; Lu, Y; Wang, B; Wang, N; Zhang, W; Zhu, H	1
Chen, L; Clemens, DL; Ding, X; Gu, J; Gui, X; Hao, X; He, Y; Ho, CM; Horwitz, MA; Lee, BY; Liu, Y; Lou, H; Ma, J; Sha, W; Sun, Q; Yang, H; Yao, L; Ying, R; Zheng, X	1

Reviews

6 review(s) available for clofazimine and isoniazid

Article	Year
A medicinal chemists' guide to the unique difficulties of lead optimization for tuberculosis. Bioorganic & medicinal chemistry letters, 2013, Sep-01, Volume: 23, Issue:17 Topics: Animals; Antitubercular Agents; Drug Discovery; Humans; Lung; Mycobacterium tuberculosis; Tuberculosis	2013
SAR analysis of new anti-TB drugs currently in pre-clinical and clinical development. European journal of medicinal chemistry, 2014, Oct-30, Volume: 86 Topics: Animals; Antitubercular Agents; Humans; Mycobacterium tuberculosis; Structure-Activity Relationship; Tuberculosis; Tuberculosis, Multidrug-Resistant	2014
Insights of synthetic analogues of anti-leprosy agents. Bioorganic & medicinal chemistry, 2019, 07-01, Volume: 27, Issue:13 Topics: Humans; Leprostatic Agents; Leprosy; Structure-Activity Relationship	2019
Tuberculosis Drug Discovery: Challenges and New Horizons. Journal of medicinal chemistry, 2022, 06-09, Volume: 65, Issue:11 Topics: Antitubercular Agents; COVID-19 Drug Treatment; Drug Discovery; Humans; Mycobacterium tuberculosis; Tuberculosis	2022
Extrapulmonary and disseminated infections due to Mycobacterium malmoense: case report and review. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1993, Volume: 16, Issue:4 Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Antitubercular Agents; Clofazimine; Gastrointestinal Diseases; Homosexuality; Humans; Isoniazid; Lung Diseases; Lymphadenitis; Male; Mycobacterium Infections, Nontuberculous; Nontuberculous Mycobacteria; Rifabutin; Rifamycins; Tenosynovitis	1993
WHO group 5 drugs and difficult multidrug-resistant tuberculosis: a systematic review with cohort analysis and meta-analysis. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:9 Topics: Acetamides; Adult; Antitubercular Agents; beta-Lactams; Clofazimine; Cohort Studies; Databases, Bibliographic; Female; Fluoroquinolones; Humans; Isoniazid; Linezolid; Macrolides; Male; Oxazolidinones; Treatment Outcome; Tuberculosis, Multidrug-Resistant	2013

Trials

7 trial(s) available for clofazimine and isoniazid

Article	Year
Rifabutin in combination with clofazimine, isoniazid and ethambutol in the treatment of AIDS patients with infections due to opportunist mycobacteria. Groupe d'Etude et de Traitement des Infections à Mycobacteries Résistantes. Tubercle, 1991, Volume: 72, Issue:3 Topics: Acquired Immunodeficiency Syndrome; Adult; Antitubercular Agents; Clofazimine; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Male; Mycobacterium Infections; Opportunistic Infections; Prospective Studies; Rifabutin; Rifamycins	1991
Controlled clinical trial of two multidrug regimens with and without rifampin in highly bacilliferous BL/LL south Indian patients: a five-year report. International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1990, Volume: 58, Issue:2 Topics: Adolescent; Adult; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Infant, Newborn; Isoniazid; Leprostatic Agents; Leprosy, Borderline; Leprosy, Lepromatous; Male; Randomized Controlled Trials as Topic; Rifampin	1990
Pyrazinamide as a part of combination therapy for BL and LL patients--a preliminary report. International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1988, Volume: 56, Issue:1 Topics: Adolescent; Adult; Animals; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Isoniazid; Leprosy; Male; Mice; Middle Aged; Muscle, Smooth; Pyrazinamide; Rifampin; Scrotum; Skin; Thioacetazone	1988
Control of the body burden of M. avium complex is associated with improved quality of life and prolonged survival of patients with AIDS: a prospective trial with rifabutin combined with isoniazid, clofazimine, ethambutol. Journal of chemotherapy (Florence, Italy), 1994, Volume: 6, Issue:3 Topics: Adult; Aged; AIDS-Related Opportunistic Infections; Body Burden; Clofazimine; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Prospective Studies; Quality of Life; Rifabutin	1994
Rifabutin versus placebo in combination with three drugs in the treatment of nontuberculous mycobacterial infection in patients with AIDS. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1996, Volume: 22, Issue:4 Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antitubercular; Antitubercular Agents; Clofazimine; Double-Blind Method; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Mycobacterium Infections; Placebos; Rifabutin	1996
Evaluation of a standardized treatment regimen of anti-tuberculosis drugs for patients with multi-drug-resistant tuberculosis (STREAM): study protocol for a randomized controlled trial. Trials, 2014, Sep-09, Volume: 15 Topics: Antitubercular Agents; Bangladesh; Clinical Protocols; Clofazimine; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Fluoroquinolones; Humans; Isoniazid; Kanamycin; Moxifloxacin; Prothionamide; Pyrazinamide; Research Design; Time Factors; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary	2014
Efficacy and safety of an innovative short-course regimen containing clofazimine for treatment of drug-susceptible tuberculosis: a clinical trial. Emerging microbes & infections, 2023, Volume: 12, Issue:1 Topics: Antitubercular Agents; Clofazimine; Drug Therapy, Combination; Humans; Isoniazid; Prothionamide; Pyrazinamide; Treatment Outcome; Tuberculosis	2023

Other Studies

53 other study(ies) available for clofazimine and isoniazid

Article	Year
Anilinopyrimidines as novel antituberculosis agents. Bioorganic & medicinal chemistry letters, 2003, May-19, Volume: 13, Issue:10 Topics: Animals; Antimalarials; Antitubercular Agents; Cell Line, Tumor; Cell Survival; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Plasmodium falciparum; Pyrimidines; Structure-Activity Relationship	2003
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4 Topics: Anti-Bacterial Agents; Antitubercular Agents; DNA, Bacterial; Drug Evaluation, Preclinical; Mycobacterium tuberculosis; Oxygen	2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. Journal of natural products, 2013, Nov-22, Volume: 76, Issue:11 Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Chromatography, High Pressure Liquid; Inhibitory Concentration 50; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nuclear Magnetic Resonance, Biomolecular; Peptides, Cyclic; Streptomyces; Vero Cells	2013
1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria. European journal of medicinal chemistry, 2014, Jul-23, Volume: 82 Topics: Antineoplastic Agents; Antitubercular Agents; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Drug Screening Assays, Antitumor; HeLa Cells; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nitrobenzenes; Structure-Activity Relationship; Triazoles; Tumor Cells, Cultured	2014
Antitubercular activity of quinolizidinyl/pyrrolizidinylalkyliminophenazines. Bioorganic & medicinal chemistry, 2014, Dec-15, Volume: 22, Issue:24 Topics: Animals; Antitubercular Agents; Cell Line; Cell Survival; Chlorocebus aethiops; Humans; Microbial Sensitivity Tests; Mycobacterium avium; Mycobacterium tuberculosis; Phenazines; Pyrrolidines; Quinolizidines; Structure-Activity Relationship; Tuberculosis; Vero Cells	2014
Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis. Journal of medicinal chemistry, 2016, Mar-24, Volume: 59, Issue:6 Topics: Animals; Antitubercular Agents; Bacteria; Cell Line; Cell Survival; Drug Design; Drug Resistance, Multiple, Bacterial; Fungi; Humans; Latent Tuberculosis; Microbial Sensitivity Tests; Microsomes; Mutagens; Mycobacterium tuberculosis; Oxazoles; Primary Cell Culture; Rifampin; Structure-Activity Relationship; Thiadiazoles	2016
S-substituted 3,5-dinitrophenyl 1,3,4-oxadiazole-2-thiols and tetrazole-5-thiols as highly efficient antitubercular agents. European journal of medicinal chemistry, 2017, Jan-27, Volume: 126 Topics: Antifungal Agents; Antitubercular Agents; Drug Design; Drug Resistance; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Oxadiazoles; Structure-Activity Relationship; Sulfhydryl Compounds; Tetrazoles	2017
Development of water-soluble 3,5-dinitrophenyl tetrazole and oxadiazole antitubercular agents. Bioorganic & medicinal chemistry, 2017, 10-15, Volume: 25, Issue:20 Topics: Antitubercular Agents; Caco-2 Cells; Cell Line; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Oxadiazoles; Solubility; Structure-Activity Relationship; Tetrazoles; Water	2017
Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase. Journal of medicinal chemistry, 2019, 09-12, Volume: 62, Issue:17 Topics: Alcohol Oxidoreductases; Antitubercular Agents; Bacterial Proteins; Dinitrobenzenes; Dose-Response Relationship, Drug; Drug Development; Hydrocarbons, Fluorinated; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Triazoles	2019
Functionalized Dioxonaphthoimidazoliums: A Redox Cycling Chemotype with Potent Bactericidal Activities against Journal of medicinal chemistry, 2021, 11-11, Volume: 64, Issue:21 Topics: Animals; Antitubercular Agents; Bacterial Proteins; Cell Wall; Genes, Reporter; Imidazoles; Microbial Sensitivity Tests; Mycobacterium tuberculosis; NADH Dehydrogenase; Oxidation-Reduction; Rats; Reactive Oxygen Species; Structure-Activity Relationship; Up-Regulation	2021
Side effects of clofazimine therapy. Leprosy in India, 1976, Volume: 48, Issue:4 Suppl Topics: Adolescent; Adult; Clofazimine; Dapsone; Female; Humans; Ichthyosis; Isoniazid; Leprosy; Male; Skin Pigmentation	1976
Emergence during unsuccessful chemotherapy of multiple drug resistance in a strain of Mycobacterium tuberculosis. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1992, Volume: 11, Issue:10 Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Antitubercular Agents; Bacteriophage Typing; Blotting, Southern; Clofazimine; Colony Count, Microbial; DNA, Bacterial; Drug Resistance, Microbial; Fluoroquinolones; Humans; Isoniazid; Lactams, Macrocyclic; Male; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Polymorphism, Restriction Fragment Length; Rifamycins; Tuberculosis, Pulmonary	1992
Quadruple-drug therapy for Mycobacterium avium-intracellulare bacteremia in AIDS patients. The Journal of infectious diseases, 1990, Volume: 161, Issue:4 Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-Infective Agents; Clofazimine; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Male; Middle Aged; Mycobacterium avium-intracellulare Infection; Rifabutin; Rifamycins; Sepsis	1990
[Drugs used in tuberculosis and leprosy]. Nihon rinsho. Japanese journal of clinical medicine, 1990, Volume: 48, Issue:10 Topics: Administration, Oral; Antibiotics, Antitubercular; Clofazimine; Dapsone; Humans; Injections, Intramuscular; Isoniazid; Leprostatic Agents; Leprosy; Rifampin; Streptomycin; Tuberculosis	1990
Multiple cold abscesses in a borderline lepromatous patient on multidrug therapy. Indian journal of leprosy, 1989, Volume: 61, Issue:4 Topics: Abscess; Adult; Clofazimine; Dapsone; Drug Therapy, Combination; Ethambutol; Hip Joint; Humans; Isoniazid; Leprosy, Borderline; Leprosy, Lepromatous; Male; Rifampin; Tuberculosis, Osteoarticular	1989
Effect of combined therapy with ansamycin, clofazimine, ethambutol, and isoniazid for Mycobacterium avium infection in patients with AIDS. The Journal of infectious diseases, 1989, Volume: 159, Issue:4 Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Anti-Bacterial Agents; Antitubercular Agents; Clofazimine; Ethambutol; Humans; Isoniazid; Lactams, Macrocyclic; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Respiratory Tract Infections; Retrospective Studies; Sepsis	1989
Susceptibility testing of slowly growing mycobacteria by a microdilution MIC method with 7H9 broth. Journal of clinical microbiology, 1986, Volume: 24, Issue:6 Topics: Anti-Bacterial Agents; Clofazimine; Ethambutol; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium avium; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Rifampin; Streptomycin; Sulfamethoxazole	1986
Effect of combined clofazimine and ansamycin therapy on Mycobacterium avium-Mycobacterium intracellulare bacteremia in patients with AIDS. The Journal of infectious diseases, 1987, Volume: 155, Issue:1 Topics: Acquired Immunodeficiency Syndrome; Amikacin; Anti-Bacterial Agents; Ciprofloxacin; Clofazimine; Cycloserine; Drug Therapy, Combination; Humans; Isoniazid; Lactams, Macrocyclic; Mycobacterium avium; Mycobacterium Infections; Mycobacterium Infections, Nontuberculous; Sepsis	1987
Recent trends in chemotherapy of leprosy. The Journal of the Association of Physicians of India, 1985, Volume: 33, Issue:9 Topics: Clofazimine; Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Isoniazid; Leprostatic Agents; Leprosy; Mycobacterium leprae; Prothionamide; Rifampin	1985
Some observations on the pharmacology of clofazimine (B663). The American journal of tropical medicine and hygiene, 1974, Volume: 23, Issue:6 Topics: Aniline Compounds; Animals; Clofazimine; Dose-Response Relationship, Drug; Feces; Humans; Isoniazid; Leprosy; Mice; Phenyl Ethers; Spectrometry, Fluorescence; Thiourea	1974
Fundamental data, methods and goals of present research on the treatment of leprosy. Zeitschrift fur Tropenmedizin und Parasitologie, 1973, Volume: 24 Topics: Animals; Animals, Laboratory; Antitubercular Agents; Clofazimine; Dapsone; Ethionamide; Humans; In Vitro Techniques; Isoniazid; Leprosy; Mice; Mycobacterium lepraemurium; Rifampin; Sulfonamides; Trimethoprim	1973
Multiple drug therapy--a comparative study with 2 tier and 3 tier combination of rifampicin, clofazimine, DDS, INAH and thiacetazone in lepromatous cases. Leprosy in India, 1981, Volume: 53, Issue:2 Topics: Adolescent; Adult; Child; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Isoniazid; Leprosy; Male; Middle Aged; Rifampin; Thioacetazone	1981
Evaluation of drug regimen in lepromatous leprosy--II. Leprosy in India, 1983, Volume: 55, Issue:2 Topics: Adult; Animals; Clofazimine; Dapsone; Drug Administration Schedule; Drug Resistance, Microbial; Humans; Isoniazid; Leprostatic Agents; Leprosy; Male; Mice; Middle Aged; Rifampin; Thioacetazone	1983
Study on drug interactions. Leprosy in India, 1980, Volume: 52, Issue:2 Topics: Adult; Clofazimine; Dapsone; Drug Interactions; Drug Therapy, Combination; Humans; Isoniazid; Leprosy; Male; Middle Aged; Rifampin	1980
In vitro and in vivo synergistic effect of isoniazid with streptomycin and clofazimine against Mycobacterium avium complex (MAC). Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 1994, Volume: 75, Issue:3 Topics: AIDS-Related Opportunistic Infections; Animals; Clofazimine; Colony Count, Microbial; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Humans; In Vitro Techniques; Isoniazid; Male; Mice; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Streptomycin	1994
Antituberculosis activities of clofazimine and its new analogs B4154 and B4157. Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:3 Topics: Animals; Antitubercular Agents; Cell Line; Clofazimine; Drug Resistance, Multiple; Female; Isoniazid; Macrophages; Male; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Rats; Rifampin; Tuberculosis	1996
The management of mycobacterial infections in HIV seropositive individuals. Jefferiss Wing Therapeutics and Protocols Group. International journal of STD & AIDS, 1996, Volume: 7, Issue:4 Topics: Adrenal Cortex Hormones; Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Antitubercular Agents; Ciprofloxacin; Clarithromycin; Clofazimine; Drug Therapy, Combination; Ethambutol; HIV Infections; Humans; Isoniazid; Mycobacterium avium-intracellulare Infection; Mycobacterium Infections; Nontuberculous Mycobacteria; Practice Guidelines as Topic; Pyrazinamide; Pyridoxine; Radiography; Rifabutin; Rifampin; Tuberculosis, Meningeal; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary	1996
Activity of a new class of isonicotinoylhydrazones used alone and in combination with isoniazid, rifampicin, ethambutol, para-aminosalicylic acid and clofazimine against Mycobacterium tuberculosis. The Journal of antimicrobial chemotherapy, 2002, Volume: 49, Issue:2 Topics: Aminosalicylic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antitubercular Agents; Chlorocebus aethiops; Clofazimine; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Ethambutol; Humans; Hydrazones; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Rifampin; Vero Cells	2002
Oxidative stress increases susceptibility of Mycobacterium tuberculosis to isoniazid. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:9 Topics: Antitubercular Agents; Bacterial Proteins; Base Sequence; Clofazimine; DNA, Bacterial; Drug Resistance, Microbial; Isoniazid; Microbial Sensitivity Tests; Molecular Sequence Data; Mycobacterium tuberculosis; Naphthoquinones; Oxidants; Oxidative Stress; Peroxidases; Superoxides	2002
[Experimental antituberculous activity of 2 derivatives of pigmented phenazine (B 663 and B 720) alone and combined with other antitubercular agents (Isoniazid and ethoniamide)]. Annales de l'Institut Pasteur, 1960, Volume: 99 Topics: Antitubercular Agents; Clofazimine; Heterocyclic Compounds; Isoniazid; Morpholines; Phenazines	1960
Should isoniazid and clofazimine be used to treat multidrug-resistant tuberculosis? The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2005, Volume: 9, Issue:2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antitubercular Agents; Clofazimine; Humans; Isoniazid; Tuberculosis, Multidrug-Resistant	2005
Mycobacterium kansasii: antibiotic susceptibility and PCR-restriction analysis of clinical isolates. Journal of medical microbiology, 2005, Volume: 54, Issue:Pt 10 Topics: Amikacin; Anti-Bacterial Agents; Brazil; Ciprofloxacin; Clarithromycin; Clofazimine; Cycloserine; DNA Fingerprinting; DNA, Bacterial; Doxycycline; Drug Resistance, Bacterial; Ethambutol; Ethionamide; Genotype; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium Infections, Nontuberculous; Mycobacterium kansasii; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Rifabutin; Rifampin; Streptomycin	2005
Tissue distribution and deposition of clofazimine in mice following oral administration with or without isoniazid. Arzneimittel-Forschung, 2007, Volume: 57, Issue:7 Topics: Animals; Chromatography, High Pressure Liquid; Clofazimine; Densitometry; Drug Interactions; Isoniazid; Leprostatic Agents; Male; Mice; Mice, Inbred BALB C; Tissue Distribution	2007
[Tissue distribution and deposition of clofazimine in mice following oral administration of isoniazid]. Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2009, Volume: 32, Issue:9 Topics: Adipose Tissue; Administration, Oral; Animals; Clofazimine; Isoniazid; Kidney; Liver; Mice; Mice, Inbred Strains; Tissue Distribution	2009
Extra-pulmonary primary multidrug-resistant tubercular lymphadenitis in an HIV negative patient. BMJ case reports, 2012, May-08, Volume: 2012 Topics: Adult; Antitubercular Agents; Clarithromycin; Clofazimine; Cycloserine; Diagnosis, Differential; Drug Therapy, Combination; Ethambutol; Ethionamide; Female; HIV Seronegativity; Humans; Isoniazid; Kanamycin; Ofloxacin; Pyrazinamide; Rifampin; Tuberculosis, Lymph Node; Tuberculosis, Multidrug-Resistant	2012
In vitro and in vivo activity of clofazimine against Mycobacterium tuberculosis persisters. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2012, Volume: 16, Issue:8 Topics: Animals; Antitubercular Agents; Aza Compounds; Chronic Disease; Clofazimine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fluoroquinolones; Isoniazid; Male; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Quinolines; Rifampin; Time Factors; Tuberculosis, Pulmonary	2012
High effectiveness of a 12-month regimen for MDR-TB patients in Cameroon. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2015, Volume: 19, Issue:5 Topics: Adolescent; Adult; Aged; Antitubercular Agents; Cameroon; Clofazimine; Cohort Studies; Confidence Intervals; Developing Countries; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Ethambutol; Female; Fluoroquinolones; Gatifloxacin; Humans; Isoniazid; Kanamycin; Male; Medication Adherence; Middle Aged; Odds Ratio; Prospective Studies; Prothionamide; Pyrazinamide; Risk Assessment; Time Factors; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Young Adult	2015
Clofazimine Contributes Sustained Antimicrobial Activity after Treatment Cessation in a Mouse Model of Tuberculosis Chemotherapy. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:5 Topics: Animals; Antitubercular Agents; Clofazimine; Disease Models, Animal; Drug Combinations; Drug Therapy, Combination; Ethambutol; Female; Isoniazid; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis; Withholding Treatment	2016
Stringent Response Factors PPX1 and PPK2 Play an Important Role in Mycobacterium tuberculosis Metabolism, Biofilm Formation, and Sensitivity to Isoniazid In Vivo. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:11 Topics: Acid Anhydride Hydrolases; Animals; Antitubercular Agents; Biofilms; Citric Acid Cycle; Clofazimine; Disease Models, Animal; Drug Resistance, Bacterial; Gene Expression; Glycerophosphates; Isoenzymes; Isoniazid; Meropenem; Mice; Mycobacterium tuberculosis; Naphthoquinones; Phosphotransferases (Phosphate Group Acceptor); Polyphosphates; Thienamycins; Tuberculosis Vaccines; Tuberculosis, Multidrug-Resistant; Vaccines, DNA; Xylose	2016
Comprehensive cost of treating one patient with MDR/pre-XDR-TB in Wellington, New Zealand. The European respiratory journal, 2016, Volume: 48, Issue:4 Topics: Adult; Amikacin; Aminosalicylic Acid; Anti-Bacterial Agents; Antitubercular Agents; Bronchoscopy; Clofazimine; Depression; Drug Costs; Emigrants and Immigrants; Ethambutol; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Health Care Costs; Humans; India; Isoniazid; Linezolid; Male; Mediastinum; Microbial Sensitivity Tests; Moxifloxacin; New Zealand; Pyrazinamide; Radiography, Thoracic; Rifampin; Schizophrenia, Paranoid; Tuberculosis, Lymph Node; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pleural; Tuberculosis, Pulmonary	2016
Clofazimine has delayed antimicrobial activity against Mycobacterium tuberculosis both in vitro and in vivo. The Journal of antimicrobial chemotherapy, 2017, Volume: 72, Issue:2 Topics: Animals; Antitubercular Agents; Bacterial Load; Clofazimine; Isoniazid; Lung; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Tuberculosis, Pulmonary	2017
Proposal for a standardised treatment regimen to manage pre- and extensively drug-resistant tuberculosis cases. The European respiratory journal, 2017, Volume: 50, Issue:1 Topics: Aminosalicylic Acid; Antitubercular Agents; Carbapenems; Clofazimine; Communicable Disease Control; Diarylquinolines; Extensively Drug-Resistant Tuberculosis; Humans; Infectious Disease Medicine; Isoniazid; Linezolid; Mycobacterium tuberculosis; Treatment Outcome; Tuberculosis, Multidrug-Resistant; World Health Organization	2017
Predicting the Outcomes of New Short-Course Regimens for Multidrug-Resistant Tuberculosis Using Intrahost and Pharmacokinetic-Pharmacodynamic Modeling. Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:12 Topics: Antitubercular Agents; Clofazimine; Colony Count, Microbial; Computer Simulation; Diarylquinolines; Dose-Response Relationship, Drug; Drug Dosage Calculations; Drug Resistance, Bacterial; Drug Therapy, Combination; Ethambutol; Host-Pathogen Interactions; Humans; Immunity, Innate; Isoniazid; Kanamycin; Macrophages; Microbial Sensitivity Tests; Models, Statistical; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Prothionamide; Pyrazinamide; Time Factors; Tuberculosis, Multidrug-Resistant	2018
Polymeric nanobiotics as a novel treatment for mycobacterial infections. Journal of controlled release : official journal of the Controlled Release Society, 2019, 11-28, Volume: 314 Topics: Animals; Antitubercular Agents; Clofazimine; Delayed-Action Preparations; Disease Models, Animal; Drug Combinations; Drug Delivery Systems; Humans; Isoniazid; Macrophages; Mycobacterium tuberculosis; Nanoparticles; Polymers; Tuberculosis; Zebrafish	2019
Effectiveness of Shorter Treatment Regimen in Multidrug-Resistant Tuberculosis Patients in Pakistan: A Multicenter Retrospective Record Review. The American journal of tropical medicine and hygiene, 2021, 03-15, Volume: 104, Issue:5 Topics: Adult; Amikacin; Antitubercular Agents; Clofazimine; Drug Administration Schedule; Drug Resistance, Multiple, Bacterial; Ethambutol; Ethionamide; Female; Humans; Isoniazid; Lost to Follow-Up; Male; Middle Aged; Moxifloxacin; Mycobacterium tuberculosis; Pakistan; Pyrazinamide; Retrospective Studies; Survival Analysis; Treatment Failure; Tuberculosis, Multidrug-Resistant	2021
Multibacillary Mid-Borderline Leprosy with Type 1 Lepra Reaction and Concurrent Latent Tuberculosis. The American journal of tropical medicine and hygiene, 2021, 10-25, Volume: 106, Issue:2 Topics: Abattoirs; Anti-Inflammatory Agents; Antitubercular Agents; Clofazimine; Dapsone; Diagnosis, Differential; Humans; Isoniazid; Latent Tuberculosis; Leprostatic Agents; Leprosy, Borderline; Leprosy, Multibacillary; Male; Middle Aged; Prednisolone; Rifampin; Thrombophlebitis	2021
Assessment of the efficacy of clofazimine alone and in combination with primary agents against Mycobacterium tuberculosis in vitro. Journal of global antimicrobial resistance, 2022, Volume: 29 Topics: Animals; Antitubercular Agents; Clofazimine; Ethambutol; Humans; Isoniazid; Mice; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis	2022
Superior Efficacy of a TBI-166, Bedaquiline, and Pyrazinamide Combination Regimen in a Murine Model of Tuberculosis. Antimicrobial agents and chemotherapy, 2022, 09-20, Volume: 66, Issue:9 Topics: Animals; Antitubercular Agents; Clofazimine; Diarylquinolines; Disease Models, Animal; Isoniazid; Linezolid; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis; Tuberculosis, Multidrug-Resistant	2022