clofazimine and ethionamide

clofazimine has been researched along with ethionamide in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199018 (45.00)18.7374
1990's9 (22.50)18.2507
2000's4 (10.00)29.6817
2010's4 (10.00)24.3611
2020's5 (12.50)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Bera, S; Mondal, D1
Castagnolo, D; Denny, WA; Dos Santos, JL; Fernandes, GFS; Thompson, AM1
Cartel, JL; Grosset, JH; Martin, PM; Moulia-Pelat, JP; Nguyen Ngoc, L; Spiegel, A1
Bourland, J; Pattyn, SR1
Groenen, G; Janssens, L; Kuykens, L; Mputu, LB; Pattyn, SR1
Deplus, S; Flageul, B; Spindler, E1
Cottenot, F; Flageul, B; Pennec, J; Vignon-Pennamen, MD; Wallach, D1
Ellard, GA2
Bourland, J; Ghys, P; Grillone, S; Groenen, G; Pattyn, SR1
Deverchin, J; Ghys, P; Groenen, G; Janssens, L; Pattyn, SR1
Bach, MA; Garraud, O; Ribierre, O1
Chatterjee, BR1
Gelber, RH1
Bach, MA; Cottenot, F; Flageul, B; Hoffenbach, A; Wallach, D1
Pattyn, SR1
Andrade, VL; Avelleira, JR; da Cunha, LH; Marques, AB1
Coussens, L; Groenen, G; Janssens, L; Kayembe, T; Nollet, E; Pattyn, SR1
Ji, BH1
Freerksen, E; Rosenfeld, M1
Jopling, WH1
Waters, MF1
Bourland, J; Davies, EM; Feracci, C; Grillone, S; Janssens, L; Pattyn, SR; Saylan, T1
Gordon, GR; Murray, JF; Peters, JH; Simmon, VF1
Brown, KE; McDougall, AC; Winsley, BE1
Leiker, DL1
Denis, P; Ghys, P; Janssens, L; Karibushi, N; Kuykens, L; Pattyn, SR; Tshilumba, K1
Cottenot, F; de Carsalade, GY; Flageul, B; Pennec, J; Spindler, E; Wallach, D1
Childs, JM; Fish, DN; Malone, RS; Peloquin, CA; Spiegel, DM1
Adam, RD; Childs, JM; Nix, DE; Peloquin, CA; Zhu, M1
Adam, RD; Auclair, B; Godo, PG; Krueger, TS; Nix, DE; Peloquin, CA1
Chimara, E; da Silva Telles, MA; Ferrazoli, L; Riley, LW1
Hassan, G; Kant, S; Parengal, J; Saheer, S1
Khalid, UK; Kumar Verma, A; Mathuria, KK; Munjal, S; Myneedu, VP; Puri, MM; Sarin, R; Singla, N; Singla, R; Vohra, V1
Dhamija, RK; Garg, D; Saroha, D; Singh, AK1
E R, V; Keny, S; Lawande, D; Parrikar, A1
Ahmad, N; Atif, M; Ghafoor, A; Iqbal, Q; Khan, S; Latif, A; Saleem, F; Wahid, A1
Antoine, R; Gaudin, C; Hartkoorn, RC1

Reviews

4 review(s) available for clofazimine and ethionamide

ArticleYear
Insights of synthetic analogues of anti-leprosy agents.
    Bioorganic & medicinal chemistry, 2019, 07-01, Volume: 27, Issue:13

    Topics: Humans; Leprostatic Agents; Leprosy; Structure-Activity Relationship

2019
Tuberculosis Drug Discovery: Challenges and New Horizons.
    Journal of medicinal chemistry, 2022, 06-09, Volume: 65, Issue:11

    Topics: Antitubercular Agents; COVID-19 Drug Treatment; Drug Discovery; Humans; Mycobacterium tuberculosis; Tuberculosis

2022
Drug resistance in leprosy--a review.
    Leprosy review, 1985, Volume: 56, Issue:4

    Topics: Animals; Clofazimine; Dapsone; Drug Resistance, Microbial; Ethionamide; Humans; Leprosy; Mice; Microbial Sensitivity Tests; Rifampin

1985
Growing points in leprosy research. 4. Recent advances in the chemotherapy of leprosy.
    Leprosy review, 1974, Volume: 45, Issue:1

    Topics: Clofazimine; Dapsone; Ethionamide; Humans; Leprosy; Rifampin; Sulfonamides; Thioacetazone; Thiourea

1974

Trials

9 trial(s) available for clofazimine and ethionamide

ArticleYear
Treatment of multibacillary leprosy with a regimen of 13 weeks duration.
    Leprosy review, 1992, Volume: 63, Issue:1

    Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Ethionamide; Humans; Leprostatic Agents; Leprosy; Prospective Studies

1992
Combined regimens of one year duration in the treatment of multibacillary leprosy--I. Combined regimens with rifampicin administered during one year.
    Leprosy review, 1989, Volume: 60, Issue:2

    Topics: Clinical Trials as Topic; Clofazimine; Cohort Studies; Dapsone; Drug Administration Schedule; Ethionamide; Female; Humans; Leprostatic Agents; Leprosy; Male; Rifampin

1989
Combined regimens of one year duration in the treatment of multibacillary leprosy--II. Combined regimens with rifampicin administered during 6 months.
    Leprosy review, 1989, Volume: 60, Issue:2

    Topics: Clinical Trials as Topic; Clofazimine; Cohort Studies; Dapsone; Drug Administration Schedule; Ethionamide; Female; Humans; Leprostatic Agents; Leprosy; Male; Rifampin

1989
Efficacy of different regimens in multibacillary leprosy.
    Leprosy review, 1986, Volume: 57 Suppl 3

    Topics: Clinical Trials as Topic; Clofazimine; Dapsone; Drug Administration Schedule; Drug Therapy, Combination; Ethionamide; Humans; Leprosy; Random Allocation; Rifampin

1986
Hepatotoxicity of the combination of rifampin-ethionamide in the treatment of multibacillary leprosy.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1984, Volume: 52, Issue:1

    Topics: Adolescent; Adult; Chemical and Drug Induced Liver Injury; Child; Clinical Trials as Topic; Clofazimine; Dapsone; Drug Therapy, Combination; Ethionamide; Female; Humans; Leprosy; Male; Middle Aged; Prospective Studies; Rifampin

1984
A randomized clinical trial of two single-dose treatments for paucibacillary leprosy.
    Leprosy review, 1994, Volume: 65, Issue:1

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Clofazimine; Dapsone; Drug Administration Schedule; Drug Therapy, Combination; Ethionamide; Female; Humans; Infant; Leprosy; Male; Middle Aged; Prognosis; Recurrence; Rifampin

1994
Daily multidrug therapy for leprosy; results of a fourteen-year experience.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1997, Volume: 65, Issue:1

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Clofazimine; Dapsone; Drug Resistance, Microbial; Drug Therapy, Combination; Erythema Nodosum; Ethionamide; Female; Follow-Up Studies; Humans; Leprostatic Agents; Leprosy, Borderline; Leprosy, Lepromatous; Leprosy, Tuberculoid; Male; Middle Aged; Recurrence; Rifampin

1997
Pharmacokinetics of cycloserine under fasting conditions and with high-fat meal, orange juice, and antacids.
    Pharmacotherapy, 2001, Volume: 21, Issue:8

    Topics: Administration, Oral; Adult; Aminosalicylic Acid; Antacids; Antibiotics, Antitubercular; Area Under Curve; Beverages; Citrus; Clofazimine; Cross-Over Studies; Cycloserine; Dietary Fats; Drug Interactions; Electrophoresis, Capillary; Ethionamide; Fasting; Female; Food-Drug Interactions; Humans; Intestinal Absorption; Male

2001
Pharmacokinetics and relative bioavailability of clofazimine in relation to food, orange juice and antacid.
    Tuberculosis (Edinburgh, Scotland), 2004, Volume: 84, Issue:6

    Topics: Administration, Oral; Adult; Aminosalicylic Acid; Antacids; Antitubercular Agents; Beverages; Biological Availability; Citrus sinensis; Clofazimine; Cross-Over Studies; Cycloserine; Dietary Fats; Drug Combinations; Drug Interactions; Ethionamide; Food; Food-Drug Interactions; Humans; Leprostatic Agents; Pyridoxine

2004

Other Studies

27 other study(ies) available for clofazimine and ethionamide

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Leprosy in French Polynesia. The possible impact of multidrug therapy on epidemiological trends.
    Leprosy review, 1992, Volume: 63, Issue:3

    Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Ethionamide; Humans; Leprosy; Polynesia; Rifampin

1992
Ambulatory treatment of multibacillary leprosy with a regimen of 8 months duration.
    Leprosy review, 1992, Volume: 63, Issue:1

    Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Ethionamide; Humans; Leprostatic Agents; Leprosy

1992
[Acute uveitis in reversal reactions].
    Acta leprologica, 1991, Volume: 7, Issue:4

    Topics: Acute Disease; Clofazimine; Drug Combinations; Ethionamide; Female; Humans; Leprosy, Lepromatous; Male; Middle Aged; Rifampin; Uveitis

1991
[Late reversal reactions in leprosy].
    Acta leprologica, 1990, Volume: 7, Issue:2

    Topics: Clofazimine; Dapsone; Drug Combinations; Ethionamide; Female; Humans; Leprosy; Male; Recurrence; Rifampin

1990
The chemotherapy of leprosy. Part 1.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1990, Volume: 58, Issue:4

    Topics: Animals; Clofazimine; Dapsone; Drug Resistance, Microbial; Drug Therapy, Combination; Ethionamide; Humans; Leprosy; Mycobacterium leprae; Prothionamide; Rifampin

1990
A follow up of T-cell subsets and of anti-M. leprae antibody titer as measured by the FLA-ABS test in Melanesian leprosy patients under polychemotherapy.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1986, Volume: 54, Issue:1

    Topics: Adolescent; Adult; Antibodies, Bacterial; Child; Clofazimine; Dapsone; Drug Therapy, Combination; Erythema Nodosum; Ethionamide; Fluorescent Antibody Technique; Humans; Leprosy; Middle Aged; Mycobacterium leprae; New Caledonia; Rifampin; T-Lymphocytes; T-Lymphocytes, Cytotoxic; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory

1986
On multi-drug combinations in the treatment of leprosy.
    Indian journal of leprosy, 1988, Volume: 60, Issue:4

    Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Ethionamide; Humans; Leprosy; Rifampin

1988
The killing of Mycobacterium leprae in mice by various dietary concentrations of clofazimine and ethionamide.
    Leprosy review, 1987, Volume: 58, Issue:4

    Topics: Administration, Oral; Animals; Clofazimine; Dose-Response Relationship, Drug; Ethionamide; Female; Leprosy; Mice; Mice, Inbred BALB C; Mycobacterium leprae

1987
Antibodies to phenolic glycolipid-1 and to whole Mycobacterium leprae in leprosy patients: evolution during therapy.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1986, Volume: 54, Issue:2

    Topics: Antibodies, Bacterial; Antigens, Bacterial; Clofazimine; Dapsone; Drug Therapy, Combination; Ethionamide; Glycolipids; Humans; Immunoglobulin G; Immunoglobulin M; Leprostatic Agents; Leprosy; Longitudinal Studies; Mycobacterium leprae; Rifampin; Time Factors

1986
Feasibility of multidrug therapy (MDT) in Hansen's disease in an urban population--Curupaiti State Hospital, Rio de Janeiro, Brazil.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1987, Volume: 55, Issue:3

    Topics: Adolescent; Adult; Brazil; Clofazimine; Dapsone; Drug Therapy, Combination; Ethionamide; Female; Humans; Leprostatic Agents; Leprosy; Male; Patient Acceptance of Health Care; Patient Compliance; Prednisolone; Prothionamide; Rifampin; Urban Population

1987
Prospective study on the relationship between intensive bactericidal therapy and leprosy reactions.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1986, Volume: 54, Issue:2

    Topics: Adult; Child; Clofazimine; Dapsone; Drug Therapy, Combination; Edema; Erythema Nodosum; Ethionamide; Female; Humans; Leprostatic Agents; Leprosy; Male; Neuritis; Prospective Studies; Rifampin

1986
Fundamental data, methods and goals of present research on the treatment of leprosy.
    Zeitschrift fur Tropenmedizin und Parasitologie, 1973, Volume: 24

    Topics: Animals; Animals, Laboratory; Antitubercular Agents; Clofazimine; Dapsone; Ethionamide; Humans; In Vitro Techniques; Isoniazid; Leprosy; Mice; Mycobacterium lepraemurium; Rifampin; Sulfonamides; Trimethoprim

1973
Side-effects of antileprosy drugs in common use.
    Leprosy review, 1983, Volume: 54, Issue:4

    Topics: Clofazimine; Dapsone; Drug Hypersensitivity; Ethionamide; Humans; Leprostatic Agents; Leprosy; Rifampin; Thioacetazone

1983
The treatment of leprosy.
    Tubercle, 1983, Volume: 64, Issue:3

    Topics: Adult; Animals; Clofazimine; Dapsone; Drug Resistance, Microbial; Erythema Nodosum; Ethionamide; Humans; Leprosy; Mycobacterium leprae; Patient Compliance; Prothionamide; Rifampin

1983
Mutagenic activity of antileprosy drugs and their derivatives.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1983, Volume: 51, Issue:1

    Topics: Clofazimine; Ethionamide; Leprostatic Agents; Mutagenicity Tests; Prothionamide; Rifampin

1983
Chemotherapy of leprosy; "bubble" or "calendar" packs for the administration of rifampin, dapsone, clofazimine, or prothionamide/ethionamide.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1983, Volume: 51, Issue:4

    Topics: Clofazimine; Dapsone; Drug Packaging; Ethionamide; Humans; Leprostatic Agents; Leprosy; Prothionamide; Rifampin; Tablets

1983
[Chemotherapy of leprosy. II. Sulfones and sulfonamides].
    Nederlands tijdschrift voor geneeskunde, 1980, Jan-12, Volume: 124, Issue:2

    Topics: Clofazimine; Drug Resistance, Microbial; Ethionamide; Humans; Leprostatic Agents; Leprosy; Prothionamide; Rifampin

1980
The effect of hemodialysis on cycloserine, ethionamide, para-aminosalicylate, and clofazimine.
    Chest, 1999, Volume: 116, Issue:4

    Topics: Adolescent; Adult; Aged; Aminosalicylic Acid; Antitubercular Agents; Biological Availability; Clofazimine; Cycloserine; Ethionamide; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Renal Dialysis

1999
Mycobacterium kansasii: antibiotic susceptibility and PCR-restriction analysis of clinical isolates.
    Journal of medical microbiology, 2005, Volume: 54, Issue:Pt 10

    Topics: Amikacin; Anti-Bacterial Agents; Brazil; Ciprofloxacin; Clarithromycin; Clofazimine; Cycloserine; DNA Fingerprinting; DNA, Bacterial; Doxycycline; Drug Resistance, Bacterial; Ethambutol; Ethionamide; Genotype; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium Infections, Nontuberculous; Mycobacterium kansasii; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Rifabutin; Rifampin; Streptomycin

2005
Extra-pulmonary primary multidrug-resistant tubercular lymphadenitis in an HIV negative patient.
    BMJ case reports, 2012, May-08, Volume: 2012

    Topics: Adult; Antitubercular Agents; Clarithromycin; Clofazimine; Cycloserine; Diagnosis, Differential; Drug Therapy, Combination; Ethambutol; Ethionamide; Female; HIV Seronegativity; Humans; Isoniazid; Kanamycin; Ofloxacin; Pyrazinamide; Rifampin; Tuberculosis, Lymph Node; Tuberculosis, Multidrug-Resistant

2012
Initial experience of bedaquiline implementation under the National TB Programme at NITRD, Delhi, India.
    The Indian journal of tuberculosis, 2019, Volume: 66, Issue:1

    Topics: Adult; Antitubercular Agents; Cardiotoxicity; Clofazimine; Cycloserine; Diarylquinolines; Drug Therapy, Combination; Electrocardiography; Ethionamide; Female; Humans; India; Linezolid; Male; Moxifloxacin; National Health Programs; Sputum; Time Factors; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary

2019
Irreversible neuropathy in extremely-drug resistant tuberculosis: An unfortunate clinical conundrum.
    The Indian journal of tuberculosis, 2020, Volume: 67, Issue:3

    Topics: Adult; Aminosalicylic Acid; Antitubercular Agents; Clofazimine; Cycloserine; Deprescriptions; Diarylquinolines; Ethionamide; Extensively Drug-Resistant Tuberculosis; Female; Humans; Kanamycin; Linezolid; Neural Conduction; Neurotoxicity Syndromes; Peripheral Nervous System Diseases; Pyrazinamide; Pyridoxine; Tuberculosis, Pulmonary

2020
Gitelman-like syndrome: A rare complication of using aminoglycosides in tuberculosis - A case report.
    The Indian journal of tuberculosis, 2020, Volume: 67, Issue:3

    Topics: Alkalosis; Antitubercular Agents; Capreomycin; Clofazimine; Cycloserine; Deprescriptions; Ethionamide; Gitelman Syndrome; Humans; Hypocalcemia; Hypokalemia; Levofloxacin; Linezolid; Male; Middle Aged; Pyrazinamide; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Water-Electrolyte Imbalance

2020
Effectiveness of Shorter Treatment Regimen in Multidrug-Resistant Tuberculosis Patients in Pakistan: A Multicenter Retrospective Record Review.
    The American journal of tropical medicine and hygiene, 2021, 03-15, Volume: 104, Issue:5

    Topics: Adult; Amikacin; Antitubercular Agents; Clofazimine; Drug Administration Schedule; Drug Resistance, Multiple, Bacterial; Ethambutol; Ethionamide; Female; Humans; Isoniazid; Lost to Follow-Up; Male; Middle Aged; Moxifloxacin; Mycobacterium tuberculosis; Pakistan; Pyrazinamide; Retrospective Studies; Survival Analysis; Treatment Failure; Tuberculosis, Multidrug-Resistant

2021
Intragenic Distribution of IS
    Microbiology spectrum, 2021, 09-03, Volume: 9, Issue:1

    Topics: Antitubercular Agents; Clofazimine; Computational Biology; DNA Transposable Elements; Drug Resistance, Bacterial; Ethionamide; Humans; Mutation; Mycobacterium tuberculosis; Tuberculosis

2021