clofazimine and bedaquiline

clofazimine has been researched along with bedaquiline in 72 studies

Research

Studies (72)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	42 (58.33)	24.3611
2020's	30 (41.67)	2.80

Authors

Authors	Studies
Barry, CE; Dartois, V	1
Biava, M; Cocozza, M; Consalvi, S; Poce, G	1
Dušek, J; Hrabálek, A; Huszár, S; Jand'ourek, O; Karabanovich, G; Klimešová, V; Kočová Vlčková, H; Konečná, K; Konyariková, Z; Korábečný, J; Korduláková, J; Kučera, T; Mikušová, K; Pávek, P; Pávková, I; Pavliš, O; Roh, J; Savková, K; Stolaříková, J; Vávrová, K	1
Ekins, S; Kyaw Zin, PP; Makarov, V; Reynolds, RC; Salina, E	1
Anderson, KS; Cabeza de Vaca, I; Deshmukh, M; Ghahremanpour, MM; Ippolito, JA; Jorgensen, WL; Liosi, ME; Tirado-Rives, J; Zhang, CH	1
Castagnolo, D; Denny, WA; Dos Santos, JL; Fernandes, GFS; Thompson, AM	1
Cole, ST; Dhar, N; Hartkoorn, RC; Mendoza-Losana, A; Sala, C; Zhang, M	1
Cole, ST; Hartkoorn, RC; Uplekar, S	1
Andries, K; Coeck, N; de Jong, BC; Gevers, T; Koul, A; Lounis, N; Thys, K; Villellas, C; Vranckx, L	1
Amoabeng, O; Mdluli, KE; Minkowski, A; Nuermberger, EL; Tasneen, R; Upton, AM; Williams, K	1
Bloemberg, GV; Böttger, EC; Bruderer, V; Hömke, R; Somoskovi, A	1
Burger, DA; Dawson, R; Diacon, AH; Donald, PR; Everitt, D; Hutchings, J; Mendel, CM; Schall, R; Symons, G; van Niekerk, C; Venter, A; von Groote-Bidlingmaier, F	1
Cole, ST; Lechartier, B	1
Andries, K; Bald, D; Cook, GM; Heineke, MH; Koul, A; Lill, H; Lu, P; van Spanning, R	1
Andries, K; Arnett, KA; Creissen, E; Henao-Tamayo, M; Lenaerts, AJ; Massoudi, L; Obregón-Henao, A; Ordway, DJ	1
Caminero, JA; Scardigli, A	1
Black, PA; Louw, GE; Pule, CM; Sampson, SL; van Helden, PD; Victor, TC; Warren, RM	1
Almeida, D; Andries, K; Grosset, J; Ioerger, T; Li, SY; Mdluli, K; Nuermberger, E; Sacchettini, J; Tyagi, S	1
Adamson, JH; Cumming, BM; Finin, PM; Jonnala, SR; Lamprecht, DA; Rahman, MA; Russell, SL; Steyn, AJ	1
Wallis, RS	1
Centis, R; D'Ambrosio, L; Enwerem, M; Lingtsang, RD; Migliori, GB; Sadutshang, TD; Tadolini, M; Tiberi, S	1
Andries, K; Coeck, N; de Jong, B; Lounis, N; Meehan, CJ; Rigouts, L; Villellas, C	1
de Moura, VC; Jackson, M; Jones, V; Li, W; North, EJ; Sanchez-Hidalgo, A	1
Akkerman, O; Aleksa, A; Alffenaar, JW; Amale, R; Artsukevich, J; Belilovski, E; Borisov, SE; Bruchfeld, J; Caminero, JA; Carpena Martinez, I; Centis, R; Codecasa, L; D'Ambrosio, L; Dalcolmo, M; Davies Forsman, L; Denholm, J; Dheda, K; Douglas, P; Duarte, R; Enwerem, M; Esmail, A; Fadul, M; Filippov, A; Gaga, M; Ganatra, S; Garcia-Fuertes, JA; García-García, JM; González Montaner, P; Gualano, G; Jonsson, J; Kunst, H; Lau, JS; Lazaro Mastrapa, B; Manga, S; Manika, K; Maryandyshev, A; Migliori, GB; Mullerpattan, J; Oelofse, S; Ortelli, M; Palmero, DJ; Palmieri, F; Papalia, A; Papavasileiou, A; Payen, MC; Pontali, E; Robalo Cordeiro, C; Romero Leyet, R; Saderi, L; Sadutshang, TD; Sanukevich, T; Skrahina, A; Solodovnikova, V; Sotgiu, G; Spanevello, A; Teran Troya, JL; Tiberi, S; Topgyal, S; Toscanini, F; Tramontana, AR; Udwadia, ZF; Viggiani, P; White, V; Zumla, A	1
Caminero, JA; Migliori, GB; Piubello, A; Scardigli, A	1
Dong, L; Fu, Y; Huang, H; Huo, F; Jing, W; Li, Y; Ma, Y; Pang, Y; Zhao, L; Zong, Z	1
Jo, KW; Nam, GB; Shim, TS; Yoon, HY	1
Almeida, DV; Barnes-Boyle, K; Li, SY; Lu, Y; Nuermberger, E; Peloquin, CA; Tasneen, R; Xu, J	1
Brill, MJE; Maartens, G; Pandie, M; Svensson, EM	1
Chen, C; Dartois, V; Dick, T; Gardete, S; Jansen, RS; Rhee, KY; Shetty, A	1
Borroni, E; Cirillo, DM; Crook, DW; Cugnata, F; Davies, TJ; Fowler, PW; Gibertoni Cruz, AL; Grazian, C; Hoosdally, SJ; Peto, TEA; Rancoita, PMV; Walker, TM	1
Ismail, N; Ismail, NA; Omar, SV; Peters, RPH	2
Ahmad, N; Ahuja, SD; Akkerman, OW; Alffenaar, JC; Anderson, LF; Baghaei, P; Bang, D; Barry, PM; Bastos, ML; Behera, D; Benedetti, A; Bisson, GP; Boeree, MJ; Bonnet, M; Brode, SK; Brust, JCM; Cai, Y; Caumes, E; Cegielski, JP; Centis, R; Chan, ED; Chan, PC; Chang, KC; Charles, M; Cirule, A; D'Ambrosio, L; Dalcolmo, MP; de Vries, G; Dheda, K; Esmail, A; Flood, J; Fox, GJ; Fréchet-Jachym, M; Fregona, G; Gayoso, R; Gegia, M; Gler, MT; Gu, S; Guglielmetti, L; Holtz, TH; Hughes, J; Isaakidis, P; Jarlsberg, L; Kempker, RR; Keshavjee, S; Khan, FA; Kipiani, M; Koenig, SP; Koh, WJ; Kritski, A; Kuksa, L; Kvasnovsky, CL; Kwak, N; Lan, Z; Lange, C; Laniado-Laborín, R; Lee, M; Leimane, V; Leung, CC; Leung, EC; Li, PZ; Lowenthal, P; Maciel, EL; Marks, SM; Mase, S; Mbuagbaw, L; Menzies, D; Migliori, GB; Milanov, V; Miller, AC; Mitnick, CD; Modongo, C; Mohr, E; Monedero, I; Nahid, P; Ndjeka, N; O'Donnell, MR; Padayatchi, N; Palmero, D; Pape, JW; Podewils, LJ; Reynolds, I; Riekstina, V; Robert, J; Rodriguez, M; Schnippel, K; Seaworth, B; Seung, KJ; Shim, TS; Singla, R; Smith, SE; Sotgiu, G; Sukhbaatar, G; Tabarsi, P; Tiberi, S; Trajman, A; Trieu, L; Udwadia, ZF; van der Werf, TS; Veziris, N; Viiklepp, P; Vilbrun, SC; Walsh, K; Westenhouse, J; Yew, WW; Yim, JJ; Zetola, NM; Zignol, M	1
Cao, P; Doan, TN; Emeto, TI; McBryde, ES; McCaw, JM	1
Bantubani, N; Chotoo, S; Conradie, F; Enwerem, M; Ferreira, H; Hughes, J; Ismail, N; Maartens, G; Master, I; Meintjes, G; Mohr, E; Ndjeka, N; Padanilam, X; Romero, R; Schnippel, K; Singh, N; Te Riele, J; Variava, E	1
Andrejak, C; Bax, H; Boeree, MJ; Brouwer, MA; Hoefsloot, W; Kunst, H; Lorent, N; Magis-Escurra, C; Rahman, A; van Groningen, H; van Ingen, J; Wagner, D; Wener, R; Zweijpfenning, SMH	1
Clemens, DL; Dillon, BJ; Ho, CM; Horwitz, MA; Lee, BY; Masleša-Galić, S; Nava, S; Silva, A	1
Aarnoutse, RE; Hoefsloot, W; Kuipers, S; Magis-Escurra, C; Pennings, LJ; Remmers, K; Ruth, MM; Sangen, JJN; Svensson, E; van Ingen, J; Wertheim, HFL; Zweijpfenning, SMH	1
Laughon, BE; Lee, SFK; Lipman, M; McHugh, TD	1
Chu, N; Dai, G; Dong, L; Huang, H; Huo, F; Jing, W; Li, Y; Lu, J; Pang, Y; Zong, Z	1
Khalid, UK; Mathuria, KK; Munjal, SK; Myneedu, VP; Puri, MM; Sarin, R; Singla, N; Singla, R; Verma, A; Vohra, V	1
Khalid, UK; Kumar Verma, A; Mathuria, KK; Munjal, S; Myneedu, VP; Puri, MM; Sarin, R; Singla, N; Singla, R; Vohra, V	1
Berube, BJ; Castro, L; Choi, SR; Narayanasamy, P; Parish, T; Russell, D	1
Baloch, AQ; Borroni, E; Cirillo, DM; Ghafoor, A; Ghodousi, A; Khanzada, FM; Qadir, M; Rizvi, AH; Tahseen, S; Trovato, A	1
Chiang, CY; de Jong, BC; Decroo, T; Ortuno-Gutierrez, N; Piubello, A; Rieder, HL; Schwoebel, V; Tahseen, S; Trébucq, A; Van Deun, A	1
Andres, S; Heyckendorf, J; Hoffmann, H; Hofmann-Thiel, S; Indra, A; Kalsdorf, B; Lange, C; Maurer, FP; Merker, M; Niemann, S; Rumetshofer, R	1
Andres, S; Ängeby, K; Barilar, I; Chryssanthou, E; Fowler, PW; Jureen, P; Kohl, TA; Köser, C; Maurer, FP; Merker, M; Moradigaravand, D; Niemann, S; Parkhill, J; Peacock, SJ; Schön, T; Walker, T	1
Ahmad, N; Baghaei, P; Barkane, L; Benedetti, A; Brode, SK; Brust, JCM; Campbell, JR; Chang, VWL; Falzon, D; Guglielmetti, L; Isaakidis, P; Kempker, RR; Kipiani, M; Kuksa, L; Lan, Z; Lange, C; Laniado-Laborín, R; Menzies, D; Nahid, P; Rodrigues, D; Singla, R; Udwadia, ZF	1
Farhat, M; Kadura, S; King, N; Köser, CU; Nakhoul, M; Theron, G; Zhu, H	1
Dhamija, RK; Garg, D; Saroha, D; Singh, AK	1
Ahidjo, BA; Boey, M; Chew, KL; Liu, Z; Octavia, S; Teo, J	1
Du, J; Gao, J; Li, L; Liu, Y; Pang, Y; Shu, W; Wang, L; Wang, Y; Xu, S; Xue, Z	1
Chan, WY; Ha, SY; Ho, KW; Ho, PL; Lam, AY; Lau, TW; So, NL; To, KK	1
Al-Shaer, MH; Alghamdi, WA; Barbakadze, K; Kempker, RR; Kipiani, M; Mikiashvili, L; Peloquin, CA	1
Basdeo, SA; Cahill, C; Cox, DJ; Gogan, KM; Gordon, SV; Keane, J; O'Connell, F; O'Sullivan, J; Phelan, JJ	1
Ardhianto, D; Fatmawati, U	1
Chew, KL; Go, J; Octavia, S; Teo, J; Yeoh, SF	1
Barilar, I; Cirillo, DM; Farhat, MR; Freschi, L; Köser, CU; Miotto, P; Niemann, S; Spitaleri, A; Tahseen, S; Vargas, R	1
Bhyat, Z; Conradie, F; Enwerem, M; Ferreira, H; Hughes, J; Ismail, F; Ismail, NA; Joseph, L; Kock, Y; Letsaolo, V; Maartens, G; Meintjes, G; Moultrie, H; Ndjeka, N; Ngcamu, D; Okozi, N; Omar, SV; Padanilam, X; Reuter, A; Romero, R; Schaaf, S; Te Riele, J; van der Meulen, M; Variava, E	1
Almoslem, M; Drusano, GL; Duncanson, B; Kim, S; Louie, A; Myrick, J; Neely, M; Nole, J; Peloquin, CA; Scanga, CA; Schmidt, S; Yamada, W	1
Abdelwahab, MT; Baker, P; Beeri, K; Bradford, Y; Brust, JCM; Denti, P; Gandhi, NR; Haas, DW; Maartens, G; Meintjes, G; Ritchie, MD; Svensson, EM; van Beek, SW; Wasserman, S	1
Ahmed, S; Bastard, M; Franke, MF; Grium Tefera, D; Hewison, C; Holtzman, D; Huerga, H; Islam, S; Jacques Leblanc, G; Khan, PY; Khan, U; Kumsa, A; Lachenal, N; Leonovich, O; Mamsa, S; Manzur-Ul-Alam, M; Melikyan, N; Mitnick, CD; Myint, Z; Osso, E; Padayachee, S; Rafi Siddiqui, M; Rashitov, M; Rich, ML; Salahuddin, N; Salia, G; Sánchez, E; Serobyan, A; Seung, KJ; Varaine, F; Vetushko, D; Yeghiazaryan, L	1
Akdoğan Kittana, FN; Hömke, R; Sander, P; Schulthess, B	1
Adam, I; Byabajungu, H; Guido, O; Joloba, ML; Kabahita, JM; Kabugo, J; Kakembo, FE; Kakooza, F; Kanyerezi, S; Kasule, GW; Lutaaya, P; Mboowa, G; Musisi, K; Nabisubi, P; Nakato, H; Namaganda, MM; Namutebi, J; Oola, D; Otim, J; Sserwadda, I	1
Chen, X; Ding, Y; Fu, L; Guo, S; Liu, H; Lu, Y; Wang, B; Wang, N; Zhang, W; Zhu, H	1
Gao, J; Gao, M; Li, L; Liu, F; Liu, Y; Pang, Y; Shu, W; Sun, Y; Xie, L; Zhang, L	1
Chen, H; Chen, N; Li, X; Liu, Y; Nie, Q; Tu, S; Xiao, F; Yao, G; Zhou, Y; Zhu, M	1
Adnan, S; Atwood, SA; Avaliani, Z; Bastard, M; Binegdie, AB; Daugarina, Z; Franke, MF; Gelin, A; Hernán, MA; Hewison, C; Huerga, H; Isani, AK; Khan, M; Khan, PY; Khan, U; Llanos, F; Manzur-Ul-Alam, M; Melikyan, A; Melikyan, N; Mitnick, CD; Nkundanyirazo, P; Putri, FA; Rich, ML; Seung, KJ; Trevisi, L; Vetushko, D; Vilbrun, C; Zarli, K	1
Carter, JJ; Cirillo, DM; Fowler, PW; Hunt, M; Iqbal, Z; Malone, KM; Merker, M; Niemann, S; Nilgiriwala, KS; Rodrigues, C; Sonnenkalb, L; Spitaleri, A; Utpatel, C	1
Chen, S; Chu, N; Dong, L; Huang, H; Huo, F; Jiang, G; Jing, W; Nie, W; Shang, Y; Shi, W; Xue, Y	1
Andries, K; Coeck, N; de Jong, BC; Mulders, W; Rigouts, L; Snobre, J; Tzfadia, O; Villellas, MC	1

Reviews

9 review(s) available for clofazimine and bedaquiline

Article	Year
A medicinal chemists' guide to the unique difficulties of lead optimization for tuberculosis. Bioorganic & medicinal chemistry letters, 2013, Sep-01, Volume: 23, Issue:17 Topics: Animals; Antitubercular Agents; Drug Discovery; Humans; Lung; Mycobacterium tuberculosis; Tuberculosis	2013
SAR analysis of new anti-TB drugs currently in pre-clinical and clinical development. European journal of medicinal chemistry, 2014, Oct-30, Volume: 86 Topics: Animals; Antitubercular Agents; Humans; Mycobacterium tuberculosis; Structure-Activity Relationship; Tuberculosis; Tuberculosis, Multidrug-Resistant	2014
Molecule Property Analyses of Active Compounds for Journal of medicinal chemistry, 2020, 09-10, Volume: 63, Issue:17 Topics: Antitubercular Agents; Bacterial Proteins; Drug Discovery; Drug Resistance, Bacterial; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Nucleoside-Phosphate Kinase; Structure-Activity Relationship; Tuberculosis	2020
Tuberculosis Drug Discovery: Challenges and New Horizons. Journal of medicinal chemistry, 2022, 06-09, Volume: 65, Issue:11 Topics: Antitubercular Agents; COVID-19 Drug Treatment; Drug Discovery; Humans; Mycobacterium tuberculosis; Tuberculosis	2022
Efflux pump inhibitors: targeting mycobacterial efflux systems to enhance TB therapy. The Journal of antimicrobial chemotherapy, 2016, Volume: 71, Issue:1 Topics: Antitubercular Agents; Biological Transport, Active; Clofazimine; Diarylquinolines; Drug Resistance, Bacterial; Humans; Membrane Transport Proteins; Mycobacterium tuberculosis	2016
Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis. Lancet (London, England), 2018, 09-08, Volume: 392, Issue:10150 Topics: Amikacin; Antitubercular Agents; Capreomycin; Carbapenems; Clofazimine; Diarylquinolines; Drug Therapy, Combination; Fluoroquinolones; Humans; Kanamycin; Levofloxacin; Linezolid; Moxifloxacin; Recurrence; Treatment Failure; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary	2018
New drugs to treat difficult tuberculous and nontuberculous mycobacterial pulmonary disease. Current opinion in pulmonary medicine, 2019, Volume: 25, Issue:3 Topics: Amikacin; Anti-Bacterial Agents; Clofazimine; Diarylquinolines; Extensively Drug-Resistant Tuberculosis; Humans; Linezolid; Liposomes; Lung Diseases; Microbial Sensitivity Tests; Mycobacterium Infections, Nontuberculous; Nitroimidazoles; Oxazoles	2019
Drug-associated adverse events in the treatment of multidrug-resistant tuberculosis: an individual patient data meta-analysis. The Lancet. Respiratory medicine, 2020, Volume: 8, Issue:4 Topics: Adult; Aminosalicylic Acid; Antitubercular Agents; Canada; Clofazimine; Diarylquinolines; Drug-Related Side Effects and Adverse Reactions; Female; Fluoroquinolones; Humans; Incidence; Linezolid; Male; Mycobacterium tuberculosis; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary	2020
Systematic review of mutations associated with resistance to the new and repurposed Mycobacterium tuberculosis drugs bedaquiline, clofazimine, linezolid, delamanid and pretomanid. The Journal of antimicrobial chemotherapy, 2020, 08-01, Volume: 75, Issue:8 Topics: Antitubercular Agents; Clofazimine; Diarylquinolines; Humans; Linezolid; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Pharmaceutical Preparations; Tuberculosis, Multidrug-Resistant	2020

Trials

3 trial(s) available for clofazimine and bedaquiline

Article	Year
Bactericidal activity of pyrazinamide and clofazimine alone and in combinations with pretomanid and bedaquiline. American journal of respiratory and critical care medicine, 2015, Apr-15, Volume: 191, Issue:8 Topics: Adult; Antitubercular Agents; Clofazimine; Diarylquinolines; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Nitroimidazoles; Pyrazinamide; Treatment Outcome; Tuberculosis; Tuberculosis, Multidrug-Resistant	2015
Improved outcomes following addition of bedaquiline and clofazimine to a treatment regimen for multidrug-resistant tuberculosis. The Journal of international medical research, 2023, Volume: 51, Issue:1 Topics: Antitubercular Agents; Clofazimine; Humans; Prospective Studies; Tuberculosis, Multidrug-Resistant	2023
Effectiveness of Bedaquiline Use beyond Six Months in Patients with Multidrug-Resistant Tuberculosis. American journal of respiratory and critical care medicine, 2023, 06-01, Volume: 207, Issue:11 Topics: Antitubercular Agents; Clofazimine; Diarylquinolines; Humans; Tuberculosis, Multidrug-Resistant	2023

Other Studies

60 other study(ies) available for clofazimine and bedaquiline

Article	Year
Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase. Journal of medicinal chemistry, 2019, 09-12, Volume: 62, Issue:17 Topics: Alcohol Oxidoreductases; Antitubercular Agents; Bacterial Proteins; Dinitrobenzenes; Dose-Response Relationship, Drug; Drug Development; Hydrocarbons, Fluorinated; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Triazoles	2019
Identification of 14 Known Drugs as Inhibitors of the Main Protease of SARS-CoV-2. ACS medicinal chemistry letters, 2020, Dec-10, Volume: 11, Issue:12 Topics:	2020
Streptomycin-starved Mycobacterium tuberculosis 18b, a drug discovery tool for latent tuberculosis. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:11 Topics: Acetamides; Amino Acid Sequence; Animals; Antitubercular Agents; Clofazimine; Diarylquinolines; Disease Models, Animal; Drug Discovery; Drugs, Investigational; Female; Genetic Engineering; Latent Tuberculosis; Linezolid; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Molecular Sequence Data; Mycobacterium tuberculosis; Oxazines; Oxazolidinones; Quinolines; Rifampin; Streptomycin; Structure-Activity Relationship; Xanthenes	2012
Cross-resistance between clofazimine and bedaquiline through upregulation of MmpL5 in Mycobacterium tuberculosis. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:5 Topics: Antitubercular Agents; Clofazimine; Diarylquinolines; Drug Resistance, Multiple, Bacterial; Mycobacterium tuberculosis	2014
Acquired resistance of Mycobacterium tuberculosis to bedaquiline. PloS one, 2014, Volume: 9, Issue:7 Topics: Animals; Antitubercular Agents; Bacterial Proteins; Base Sequence; Clofazimine; Diarylquinolines; Drug Resistance, Bacterial; Genes, Bacterial; Genetic Fitness; Humans; Mice; Microbial Sensitivity Tests; Models, Biological; Molecular Sequence Data; Mutation; Mycobacterium tuberculosis; Reserpine; Tuberculosis; Up-Regulation; Verapamil	2014
Contribution of the nitroimidazoles PA-824 and TBA-354 to the activity of novel regimens in murine models of tuberculosis. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:1 Topics: Animals; Antitubercular Agents; Clofazimine; Diarylquinolines; Disease Models, Animal; Drug Therapy, Combination; Female; Fluoroquinolones; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Nitroimidazoles; Oxazines; Oxazoles; Pyrazinamide; Random Allocation; Tuberculosis	2015
A mutation associated with clofazimine and bedaquiline cross-resistance in MDR-TB following bedaquiline treatment. The European respiratory journal, 2015, Volume: 45, Issue:2 Topics: Antitubercular Agents; Clofazimine; Diarylquinolines; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Phenotype; Quinolines; Treatment Outcome; Tuberculosis, Multidrug-Resistant	2015
Mode of Action of Clofazimine and Combination Therapy with Benzothiazinones against Mycobacterium tuberculosis. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:8 Topics: Animals; Antitubercular Agents; Clofazimine; Diarylquinolines; Drug Therapy, Combination; Female; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Piperazines; Thiazines; Tuberculosis, Multidrug-Resistant; Vitamin K 2	2015
The cytochrome bd-type quinol oxidase is important for survival of Mycobacterium smegmatis under peroxide and antibiotic-induced stress. Scientific reports, 2015, May-27, Volume: 5 Topics: Anti-Bacterial Agents; ATP Synthetase Complexes; Bacterial Proteins; Clofazimine; Diarylquinolines; Electron Transport Complex IV; Gene Knockout Techniques; Hydrogen Peroxide; Mutation; Mycobacterium smegmatis; NADH Dehydrogenase; Quinolones; Reactive Oxygen Species; Stress, Physiological	2015
Susceptibility of Mycobacterium abscessus to antimycobacterial drugs in preclinical models. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:11 Topics: Animals; Anti-Bacterial Agents; Clarithromycin; Clofazimine; Diarylquinolines; Granulocyte-Macrophage Colony-Stimulating Factor; Mice; Mice, Knockout; Mice, SCID; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium Infections	2015
Classification of antituberculosis drugs: a new proposal based on the most recent evidence. The European respiratory journal, 2015, Volume: 46, Issue:4 Topics: Antitubercular Agents; Carbapenems; Clavulanic Acid; Clofazimine; Diarylquinolines; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Humans; Infectious Disease Medicine; Linezolid; Nitroimidazoles; Oxazoles; Practice Guidelines as Topic; Tuberculosis, Multidrug-Resistant; World Health Organization	2015
Mutations in pepQ Confer Low-Level Resistance to Bedaquiline and Clofazimine in Mycobacterium tuberculosis. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:8 Topics: Animals; Antitubercular Agents; Clofazimine; Diarylquinolines; Female; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Tuberculosis, Multidrug-Resistant	2016
Turning the respiratory flexibility of Mycobacterium tuberculosis against itself. Nature communications, 2016, 08-10, Volume: 7 Topics: Adenosine Triphosphate; Animals; Antitubercular Agents; Clofazimine; Diarylquinolines; Drug Therapy, Combination; Electron Transport Chain Complex Proteins; Hep G2 Cells; Humans; Imidazoles; Inhibitory Concentration 50; Macrophages; Mice; Mutation; Mycobacterium tuberculosis; Piperidines; Pyridines; RAW 264.7 Cells; Reactive Oxygen Species; Tuberculosis, Multidrug-Resistant	2016
Cardiac safety of extensively drug-resistant tuberculosis regimens including bedaquiline, delamanid and clofazimine. The European respiratory journal, 2016, Volume: 48, Issue:5 Topics: Antitubercular Agents; Clofazimine; Diarylquinolines; Extensively Drug-Resistant Tuberculosis; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant	2016
Cardiac safety of extensively drug-resistant tuberculosis regimens including bedaquiline, delamanid and clofazimine. The European respiratory journal, 2016, Volume: 48, Issue:5 Topics: Antitubercular Agents; Clofazimine; Diarylquinolines; Extensively Drug-Resistant Tuberculosis; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant	2016
Unexpected high prevalence of resistance-associated Rv0678 variants in MDR-TB patients without documented prior use of clofazimine or bedaquiline. The Journal of antimicrobial chemotherapy, 2017, 03-01, Volume: 72, Issue:3 Topics: Anti-Inflammatory Agents; Antibiotics, Antitubercular; Antitubercular Agents; Clinical Trials as Topic; Clofazimine; Diarylquinolines; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Prevalence; Rifampin; Sequence Analysis, DNA; Tuberculosis, Multidrug-Resistant	2017
Synergistic Interactions of MmpL3 Inhibitors with Antitubercular Compounds Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:4 Topics: Antitubercular Agents; beta-Lactams; Clofazimine; Diarylquinolines; Drug Synergism; Membrane Transport Proteins; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Mycolic Acids; Rifampin	2017
Effectiveness and safety of bedaquiline-containing regimens in the treatment of MDR- and XDR-TB: a multicentre study. The European respiratory journal, 2017, Volume: 49, Issue:5 Topics: Adult; Antitubercular Agents; Carbapenems; Clofazimine; Cohort Studies; Diarylquinolines; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Female; HIV Infections; Humans; Linezolid; Male; Middle Aged; Patient Safety; Retrospective Studies; Sputum; Treatment Outcome; Tuberculosis, Multidrug-Resistant	2017
Proposal for a standardised treatment regimen to manage pre- and extensively drug-resistant tuberculosis cases. The European respiratory journal, 2017, Volume: 50, Issue:1 Topics: Aminosalicylic Acid; Antitubercular Agents; Carbapenems; Clofazimine; Communicable Disease Control; Diarylquinolines; Extensively Drug-Resistant Tuberculosis; Humans; Infectious Disease Medicine; Isoniazid; Linezolid; Mycobacterium tuberculosis; Treatment Outcome; Tuberculosis, Multidrug-Resistant; World Health Organization	2017
Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:10 Topics: Antitubercular Agents; Beijing; China; Clofazimine; Diarylquinolines; DNA Gyrase; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Gatifloxacin; Humans; Linezolid; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles	2017
Clinical significance of QT-prolonging drug use in patients with MDR-TB or NTM disease. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2017, 09-01, Volume: 21, Issue:9 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Azithromycin; Child; Clarithromycin; Clofazimine; Diarylquinolines; Female; Fluoroquinolones; Follow-Up Studies; Humans; Lost to Follow-Up; Macrolides; Male; Middle Aged; Moxifloxacin; Mycobacterium Infections, Nontuberculous; Mycobacterium tuberculosis; Nitroimidazoles; Nontuberculous Mycobacteria; Oxazoles; Retrospective Studies; Tuberculosis, Multidrug-Resistant; Young Adult	2017
Verapamil Increases the Bioavailability and Efficacy of Bedaquiline but Not Clofazimine in a Murine Model of Tuberculosis. Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:1 Topics: Animals; Antitubercular Agents; Biological Availability; Calcium Channel Blockers; Clofazimine; Colony Count, Microbial; Diarylquinolines; Drug Resistance, Bacterial; Female; Lung; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Tuberculosis; Verapamil	2018
Pharmacokinetic interaction between bedaquiline and clofazimine in patients with drug-resistant tuberculosis. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2018, 01-01, Volume: 22, Issue:1 Topics: Adult; Antitubercular Agents; Biological Availability; Clofazimine; Diarylquinolines; Drug Interactions; Female; Humans; Male; Middle Aged; Models, Biological; Tuberculosis, Multidrug-Resistant; Young Adult	2018
Verapamil Targets Membrane Energetics in Mycobacterium tuberculosis. Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:5 Topics: Animals; Antitubercular Agents; Calcium Channel Blockers; Cell Membrane; Clofazimine; Diarylquinolines; Drug Synergism; Female; Humans; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Verapamil	2018
Validating a 14-Drug Microtiter Plate Containing Bedaquiline and Delamanid for Large-Scale Research Susceptibility Testing of Mycobacterium tuberculosis. Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:9 Topics: Antitubercular Agents; Clofazimine; Diarylquinolines; Drug Resistance, Multiple, Bacterial; Humans; Linezolid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Reproducibility of Results; Tuberculosis; Tuberculosis, Multidrug-Resistant	2018
In vitro approaches for generation of Mycobacterium tuberculosis mutants resistant to bedaquiline, clofazimine or linezolid and identification of associated genetic variants. Journal of microbiological methods, 2018, Volume: 153 Topics: Antitubercular Agents; Bacteriological Techniques; Clofazimine; Diarylquinolines; Drug Resistance, Multiple, Bacterial; Genetic Variation; Genotype; Humans; Linezolid; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Phenotype; Tuberculosis, Multidrug-Resistant	2018
Predicting the Outcomes of New Short-Course Regimens for Multidrug-Resistant Tuberculosis Using Intrahost and Pharmacokinetic-Pharmacodynamic Modeling. Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:12 Topics: Antitubercular Agents; Clofazimine; Colony Count, Microbial; Computer Simulation; Diarylquinolines; Dose-Response Relationship, Drug; Drug Dosage Calculations; Drug Resistance, Bacterial; Drug Therapy, Combination; Ethambutol; Host-Pathogen Interactions; Humans; Immunity, Innate; Isoniazid; Kanamycin; Macrophages; Microbial Sensitivity Tests; Models, Statistical; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Prothionamide; Pyrazinamide; Time Factors; Tuberculosis, Multidrug-Resistant	2018
High treatment success rate for multidrug-resistant and extensively drug-resistant tuberculosis using a bedaquiline-containing treatment regimen. The European respiratory journal, 2018, Volume: 52, Issue:6 Topics: Adult; Anti-HIV Agents; Antitubercular Agents; Clofazimine; Diarylquinolines; Drug Resistance, Bacterial; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Female; Fluoroquinolones; HIV Infections; Humans; Levofloxacin; Linezolid; Male; Middle Aged; Poisson Distribution; South Africa; Treatment Outcome; Tuberculosis, Multidrug-Resistant	2018
Clofazimine does not lead to significant QT interval prolongation: a multicentre study. The European respiratory journal, 2018, Volume: 52, Issue:5 Topics: Arrhythmias, Cardiac; Clofazimine; Diarylquinolines; Heart; Humans; Long QT Syndrome	2018
Ultra-rapid near universal TB drug regimen identified via parabolic response surface platform cures mice of both conventional and high susceptibility. PloS one, 2018, Volume: 13, Issue:11 Topics: Adamantane; Animals; Antitubercular Agents; Clofazimine; Diarylquinolines; Disease Models, Animal; Drug Combinations; Ethylenediamines; Humans; Lung; Mice; Mycobacterium tuberculosis; Pyrazinamide; Tuberculosis	2018
Clofazimine Exposure Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:3 Topics: Antitubercular Agents; Clofazimine; Diarylquinolines; Drug Resistance, Multiple, Bacterial; Membrane Transport Proteins; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Tuberculosis, Multidrug-Resistant	2019
A bedaquiline/clofazimine combination regimen might add activity to the treatment of clinically relevant non-tuberculous mycobacteria. The Journal of antimicrobial chemotherapy, 2019, 04-01, Volume: 74, Issue:4 Topics: Antitubercular Agents; Clofazimine; Diarylquinolines; Drug Synergism; Microbial Sensitivity Tests; Microbial Viability; Mycobacterium abscessus; Mycobacterium avium Complex; Mycobacterium tuberculosis	2019
No in vitro synergistic effect of bedaquiline combined with fluoroquinolones, linezolid, and clofazimine against extensively drug-resistant tuberculosis. Diagnostic microbiology and infectious disease, 2019, Volume: 94, Issue:4 Topics: Antitubercular Agents; Clofazimine; Diarylquinolines; Drug Synergism; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Linezolid; Microbial Sensitivity Tests; Mycobacterium tuberculosis	2019
Early efficacy and safety of Bedaquiline and Delamanid given together in a "Salvage Regimen" for treatment of drug-resistant tuberculosis. The Indian journal of tuberculosis, 2019, Volume: 66, Issue:1 Topics: Adult; Cardiotoxicity; Clofazimine; Diarylquinolines; Drug Therapy, Combination; Electrocardiography; Female; Humans; Imipenem; Male; Moxifloxacin; Nitroimidazoles; Oxazoles; Salvage Therapy; Sputum; Survival Rate; Tuberculosis, Multidrug-Resistant; Young Adult	2019
Initial experience of bedaquiline implementation under the National TB Programme at NITRD, Delhi, India. The Indian journal of tuberculosis, 2019, Volume: 66, Issue:1 Topics: Adult; Antitubercular Agents; Cardiotoxicity; Clofazimine; Cycloserine; Diarylquinolines; Drug Therapy, Combination; Electrocardiography; Ethionamide; Female; Humans; India; Linezolid; Male; Moxifloxacin; National Health Programs; Sputum; Time Factors; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary	2019
Novel MenA Inhibitors Are Bactericidal against Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:6 Topics: Antitubercular Agents; Bacterial Proteins; Clofazimine; Diarylquinolines; Electron Transport; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Oxidation-Reduction	2019
Acquisition of Cross-Resistance to Bedaquiline and Clofazimine following Treatment for Tuberculosis in Pakistan. Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:9 Topics: Antitubercular Agents; Clofazimine; Diarylquinolines; Drug Resistance, Microbial; Drug Resistance, Multiple, Bacterial; Humans; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Pakistan; Retrospective Studies; Tuberculosis; Whole Genome Sequencing	2019
World Health Organization 2018 treatment guidelines for rifampicin-resistant tuberculosis: uncertainty, potential risks and the way forward. International journal of antimicrobial agents, 2020, Volume: 55, Issue:1 Topics: Antitubercular Agents; Clofazimine; Diarylquinolines; Humans; Linezolid; Mycobacterium tuberculosis; Rifampin; Tuberculosis, Pulmonary	2020
Bedaquiline-Resistant Tuberculosis: Dark Clouds on the Horizon. American journal of respiratory and critical care medicine, 2020, 06-15, Volume: 201, Issue:12 Topics: Antitubercular Agents; Clofazimine; Diarylquinolines; Drug Resistance, Multiple, Bacterial; Germany; Humans; Mycobacterium tuberculosis; Practice Guidelines as Topic; Tuberculosis, Multidrug-Resistant; World Health Organization	2020
Phylogenetically informative mutations in genes implicated in antibiotic resistance in Mycobacterium tuberculosis complex. Genome medicine, 2020, 03-06, Volume: 12, Issue:1 Topics: Antitubercular Agents; Clofazimine; Diarylquinolines; Drug Resistance, Bacterial; Genes, MDR; Inhibitory Concentration 50; Mutation; Mycobacterium tuberculosis; Phylogeny	2020
Irreversible neuropathy in extremely-drug resistant tuberculosis: An unfortunate clinical conundrum. The Indian journal of tuberculosis, 2020, Volume: 67, Issue:3 Topics: Adult; Aminosalicylic Acid; Antitubercular Agents; Clofazimine; Cycloserine; Deprescriptions; Diarylquinolines; Ethionamide; Extensively Drug-Resistant Tuberculosis; Female; Humans; Kanamycin; Linezolid; Neural Conduction; Neurotoxicity Syndromes; Peripheral Nervous System Diseases; Pyrazinamide; Pyridoxine; Tuberculosis, Pulmonary	2020
MIC Ranges of Quality Control Strain Mycobacterium peregrinum ATCC 700686 against Rifabutin, Eravacycline, Delafloxacin, Clofazimine, and Bedaquiline. Journal of clinical microbiology, 2020, 12-17, Volume: 59, Issue:1 Topics: Antitubercular Agents; Clofazimine; Diarylquinolines; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Mycobacteriaceae; Mycobacterium tuberculosis; Quality Control; Rifabutin; Tetracyclines	2020
Acquisition of clofazimine resistance following bedaquiline treatment for multidrug-resistant tuberculosis. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2021, Volume: 102 Topics: Antitubercular Agents; China; Clofazimine; Cohort Studies; Diarylquinolines; Drug Resistance, Multiple, Bacterial; Female; Genotype; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Mutation; Mycobacterium tuberculosis; Tuberculosis, Multidrug-Resistant	2021
A child with acute myeloid leukemia complicated by calcaneal osteomyelitis due to Mycobacterium abscessus infection after induction chemotherapy successfully salvaged with bedaquiline and clofazimine. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2021, Volume: 103 Topics: Anti-Bacterial Agents; Child, Preschool; Clofazimine; Combined Modality Therapy; Diarylquinolines; Drug Therapy, Combination; Female; Humans; Immunocompromised Host; Induction Chemotherapy; Leukemia, Myeloid, Acute; Mycobacterium Infections, Nontuberculous; Osteomyelitis; Salvage Therapy	2021
Pharmacokinetics of bedaquiline, delamanid and clofazimine in patients with multidrug-resistant tuberculosis. The Journal of antimicrobial chemotherapy, 2021, 03-12, Volume: 76, Issue:4 Topics: Antitubercular Agents; Clofazimine; Diarylquinolines; Humans; Nitroimidazoles; Oxazoles; Prospective Studies; Tuberculosis, Multidrug-Resistant	2021
The Iron Chelator Desferrioxamine Increases the Efficacy of Bedaquiline in Primary Human Macrophages Infected with BCG. International journal of molecular sciences, 2021, Mar-13, Volume: 22, Issue:6 Topics: Amikacin; Antitubercular Agents; Bacterial Load; Cell Survival; Clofazimine; Cycloserine; Deferoxamine; Diarylquinolines; Drug Resistance, Bacterial; Drug Synergism; Gene Expression; Humans; Interferon-gamma; Interleukin-1beta; Interleukin-6; Iron; Iron Chelating Agents; Linezolid; Macrophages; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium bovis; Primary Cell Culture; Pyrazinamide	2021
Analysis of the side effect of QTc interval prolongation in the bedaquiline regimen in drug resistant tuberculosis patients. Journal of basic and clinical physiology and pharmacology, 2021, Jun-25, Volume: 32, Issue:4 Topics: Antitubercular Agents; Clofazimine; Diarylquinolines; Drug-Related Side Effects and Adverse Reactions; Electrocardiography; Humans; Long QT Syndrome; Retrospective Studies; Tuberculosis, Multidrug-Resistant	2021
MIC Distributions of Routinely Tested Antimicrobials and of Rifabutin, Eravacycline, Delafloxacin, Clofazimine, and Bedaquiline for Mycobacterium fortuitum. Antimicrobial agents and chemotherapy, 2021, 09-17, Volume: 65, Issue:10 Topics: Anti-Infective Agents; Antitubercular Agents; Clofazimine; Diarylquinolines; Fluoroquinolones; Microbial Sensitivity Tests; Mycobacterium fortuitum; Rifabutin; Tetracyclines	2021
Role of Epistasis in Amikacin, Kanamycin, Bedaquiline, and Clofazimine Resistance in Mycobacterium tuberculosis Complex. Antimicrobial agents and chemotherapy, 2021, 10-18, Volume: 65, Issue:11 Topics: Amikacin; Antitubercular Agents; Clofazimine; Diarylquinolines; Drug Resistance, Multiple, Bacterial; Epistasis, Genetic; Humans; Kanamycin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Tuberculosis, Multidrug-Resistant	2021
Assessment of epidemiological and genetic characteristics and clinical outcomes of resistance to bedaquiline in patients treated for rifampicin-resistant tuberculosis: a cross-sectional and longitudinal study. The Lancet. Infectious diseases, 2022, Volume: 22, Issue:4 Topics: Antitubercular Agents; Clofazimine; Cross-Sectional Studies; Diarylquinolines; Humans; Longitudinal Studies; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Rifampin; Tuberculosis, Multidrug-Resistant	2022
Evaluating the effect of clofazimine against Mycobacterium tuberculosis given alone or in combination with pretomanid, bedaquiline or linezolid. International journal of antimicrobial agents, 2022, Volume: 59, Issue:2 Topics: Antitubercular Agents; Clofazimine; Diarylquinolines; Humans; Linezolid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Tuberculosis, Multidrug-Resistant	2022
Pharmacogenetics of Between-Individual Variability in Plasma Clearance of Bedaquiline and Clofazimine in South Africa. The Journal of infectious diseases, 2022, 08-12, Volume: 226, Issue:1 Topics: Antitubercular Agents; Clofazimine; Cytochrome P-450 CYP3A; Diarylquinolines; Genome-Wide Association Study; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pharmacogenetics; South Africa; Tuberculosis, Multidrug-Resistant; Vitamin K Epoxide Reductases	2022
Safety and Effectiveness Outcomes From a 14-Country Cohort of Patients With Multi-Drug Resistant Tuberculosis Treated Concomitantly With Bedaquiline, Delamanid, and Other Second-Line Drugs. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2022, 10-12, Volume: 75, Issue:8 Topics: Antitubercular Agents; Clofazimine; Cohort Studies; Diarylquinolines; Electrolytes; Fluoroquinolones; Humans; Linezolid; Nitroimidazoles; Oxazoles; Prospective Studies; Rifampin; Tuberculosis, Multidrug-Resistant	2022
Antimicrobial agents and chemotherapy, 2022, 05-17, Volume: 66, Issue:5 Topics: Anti-Bacterial Agents; Antitubercular Agents; Clofazimine; Diarylquinolines; Humans; Microbial Sensitivity Tests; Mycobacterium abscessus; Mycobacterium Infections, Nontuberculous	2022
First report of whole-genome analysis of an extensively drug-resistant Mycobacterium tuberculosis clinical isolate with bedaquiline, linezolid and clofazimine resistance from Uganda. Antimicrobial resistance and infection control, 2022, 05-12, Volume: 11, Issue:1 Topics: Adult; Antitubercular Agents; Clofazimine; Diarylquinolines; Extensively Drug-Resistant Tuberculosis; Humans; Linezolid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Rifampin; Tuberculosis, Multidrug-Resistant; Uganda	2022
Superior Efficacy of a TBI-166, Bedaquiline, and Pyrazinamide Combination Regimen in a Murine Model of Tuberculosis. Antimicrobial agents and chemotherapy, 2022, 09-20, Volume: 66, Issue:9 Topics: Animals; Antitubercular Agents; Clofazimine; Diarylquinolines; Disease Models, Animal; Isoniazid; Linezolid; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis; Tuberculosis, Multidrug-Resistant	2022
Development and Validation of a Nomogram for Prediction of QT Interval Prolongation in Patients Administered Bedaquiline-Containing Regimens in China: a Modeling Study. Antimicrobial agents and chemotherapy, 2022, 09-20, Volume: 66, Issue:9 Topics: Antitubercular Agents; Clofazimine; Creatinine; Diarylquinolines; Humans; Levofloxacin; Long QT Syndrome; Moxifloxacin; Nomograms; Tuberculosis, Multidrug-Resistant	2022
Bedaquiline and clofazimine resistance in Mycobacterium tuberculosis: an in-vitro and in-silico data analysis. The Lancet. Microbe, 2023, Volume: 4, Issue:5 Topics: Antitubercular Agents; Clofazimine; Diarylquinolines; Mycobacterium tuberculosis	2023
Bedaquiline resistance pattern in clofazimine-resistant clinical isolates of tuberculosis patients. Journal of global antimicrobial resistance, 2023, Volume: 33 Topics: Antitubercular Agents; Clofazimine; Diarylquinolines; Humans; Tuberculosis	2023
Bedaquiline- and clofazimine- selected Mycobacterium tuberculosis mutants: further insights on resistance driven largely by Rv0678. Scientific reports, 2023, 06-27, Volume: 13, Issue:1 Topics: Antitubercular Agents; Clofazimine; Diarylquinolines; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Tuberculosis, Multidrug-Resistant	2023