Page last updated: 2024-09-03

clofarabine and resveratrol

clofarabine has been researched along with resveratrol in 7 studies

Compound Research Comparison

Studies
(clofarabine)
Trials
(clofarabine)
Recent Studies (post-2010)
(clofarabine)
Studies
(resveratrol)
Trials
(resveratrol)
Recent Studies (post-2010) (resveratrol)
42410128010,9312417,998

Protein Interaction Comparison

ProteinTaxonomyclofarabine (IC50)resveratrol (IC50)
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
M18 aspartyl aminopeptidasePlasmodium falciparum 3D72.242
VifHuman immunodeficiency virus 125.31
DNA dC->dU-editing enzyme APOBEC-3G isoform 1Homo sapiens (human)25.31
Transient receptor potential cation channel subfamily A member 1Homo sapiens (human)0.75
Amyloid-beta precursor proteinHomo sapiens (human)2.6
Cytochrome P450 1A2Homo sapiens (human)3
Prostaglandin G/H synthase 1Ovis aries (sheep)2.025
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)2.312
Luciferin 4-monooxygenasePhotinus pyralis (common eastern firefly)0.0589
Cytochrome P450 3A4Homo sapiens (human)0.6
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)0.685
DNA polymerase alpha catalytic subunitHomo sapiens (human)3.3
Polyunsaturated fatty acid 5-lipoxygenaseHomo sapiens (human)4.9
AromataseHomo sapiens (human)0.96
Cytochrome P450 2C9 Homo sapiens (human)7
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)0.685
TyrosinaseHomo sapiens (human)5.35
Ribosyldihydronicotinamide dehydrogenase [quinone]Homo sapiens (human)1.3972
Nuclear factor NF-kappa-B p105 subunitHomo sapiens (human)2.5
Amine oxidase [flavin-containing] AHomo sapiens (human)2.4945
Prostaglandin G/H synthase 1Homo sapiens (human)0.8517
Sodium-dependent noradrenaline transporter Homo sapiens (human)2.312
Amine oxidase [flavin-containing] BHomo sapiens (human)5.01
Dipeptidyl peptidase 4Homo sapiens (human)0.0006
Cytochrome P450 2C19Homo sapiens (human)3
Prostaglandin G/H synthase 2Homo sapiens (human)1.672
Prostaglandin G/H synthase 2Ovis aries (sheep)3.49
Nuclear factor NF-kappa-B p100 subunit Homo sapiens (human)2.5
Transcription factor p65Homo sapiens (human)2.5
Cytochrome P450 1B1Homo sapiens (human)1.4
Transient receptor potential cation channel subfamily A member 1Rattus norvegicus (Norway rat)1.63
large T antigenBetapolyomavirus macacae26.2

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bonnac, L; Clouser, CL; Daly, MB; Kim, B; Landman, SR; Mansky, LM; Patterson, SE; Rawson, JM; Reilly, CS; Roth, ME; Xie, J1
Cho, MK; Choi, YJ; Im, JH; Kim, YB; Lee, SH; Lee, YJ; Nam, HS; Won, SY1
Cho, MK; Im, JH; Lee, DM; Lee, SH; Lee, YJ; Nam, HS; Park, JS; Won, SY1
Cho, MK; Lee, SH; Lee, YJ; Nam, HS; Oh, MH; Park, IS; Park, JW; Shim, JH1
Lee, SH; Lee, YJ1
Choi, YJ; Hwang, IS; Kim, SH; Lee, CH; Lee, SH; Lee, YJ; Nam, HS1
Fabianowska-Majewska, K; Kaufman-Szymczyk, A; Lubecka, K; Majda, K; Szuławska-Mroczek, A1

Other Studies

7 other study(ies) available for clofarabine and resveratrol

ArticleYear
Synergistic reduction of HIV-1 infectivity by 5-azacytidine and inhibitors of ribonucleotide reductase.
    Bioorganic & medicinal chemistry, 2016, 06-01, Volume: 24, Issue:11

    Topics: Anti-HIV Agents; Azacitidine; Dose-Response Relationship, Drug; Enzyme Inhibitors; HIV Infections; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Structure; Ribonucleotide Reductases; Structure-Activity Relationship

2016
Synergistic anti-cancer effects of resveratrol and chemotherapeutic agent clofarabine against human malignant mesothelioma MSTO-211H cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 52

    Topics: Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Cell Line, Tumor; Cell Proliferation; Chromones; Clofarabine; Cyclin D1; Enzyme Inhibitors; Epithelial Cells; Humans; Mesothelioma; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-met; Resveratrol; Sp1 Transcription Factor; Stilbenes

2013
Synergistic inhibition of mesothelioma cell growth by the combination of clofarabine and resveratrol involves Nrf2 downregulation.
    BMB reports, 2012, Volume: 45, Issue:11

    Topics: Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arabinonucleosides; Blotting, Western; Cell Proliferation; Clofarabine; Down-Regulation; Drug Synergism; Heme Oxygenase-1; Humans; Mesothelioma; NF-E2-Related Factor 2; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Resveratrol; RNA, Small Interfering; Signal Transduction; Stilbenes; Tumor Cells, Cultured

2012
Resveratrol contributes to chemosensitivity of malignant mesothelioma cells with activation of p53.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2014, Volume: 63

    Topics: Adenine Nucleotides; Anticarcinogenic Agents; Antineoplastic Agents; Arabinonucleosides; Base Sequence; Cell Line, Tumor; Clofarabine; DNA Primers; G1 Phase; Genes, p53; Humans; Mesothelioma; Oncogene Proteins; Polymerase Chain Reaction; Resveratrol; Stilbenes

2014
Resveratrol and clofarabine induces a preferential apoptosis-activating effect on malignant mesothelioma cells by Mcl-1 down-regulation and caspase-3 activation.
    BMB reports, 2015, Volume: 48, Issue:3

    Topics: Adenine Nucleotides; Apoptosis; Arabinonucleosides; Caspase 3; Cell Line, Tumor; Clofarabine; Down-Regulation; Enzyme Activation; Humans; Mesothelioma; Myeloid Cell Leukemia Sequence 1 Protein; Resveratrol; Stilbenes

2015
Knockdown of Bcl-xL enhances growth-inhibiting and apoptosis-inducing effects of resveratrol and clofarabine in malignant mesothelioma H-2452 cells.
    Journal of Korean medical science, 2014, Volume: 29, Issue:11

    Topics: Adenine Nucleotides; Antimetabolites, Antineoplastic; Apoptosis; Arabinonucleosides; bcl-X Protein; Caspase 3; Caspase 7; Cell Line, Tumor; Cell Proliferation; Clofarabine; G2 Phase Cell Cycle Checkpoints; Gene Knockdown Techniques; Humans; Leupeptins; Lung Neoplasms; M Phase Cell Cycle Checkpoints; Mesothelioma; Mesothelioma, Malignant; Myeloid Cell Leukemia Sequence 1 Protein; Resveratrol; RNA Interference; RNA, Messenger; RNA, Small Interfering; Stilbenes

2014
Clofarabine‑phytochemical combination exposures in CML cells inhibit DNA methylation machinery, upregulate tumor suppressor genes and promote caspase‑dependent apoptosis.
    Molecular medicine reports, 2019, Volume: 20, Issue:4

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Cell Line, Tumor; Clofarabine; Cyclin-Dependent Kinase Inhibitor p21; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Drug Synergism; Epigenesis, Genetic; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Resveratrol; Tretinoin

2019