clofarabine has been researched along with gemcitabine in 11 studies
| Studies (clofarabine) | Trials (clofarabine) | Recent Studies (post-2010) (clofarabine) | Studies (gemcitabine) | Trials (gemcitabine) | Recent Studies (post-2010) (gemcitabine) |
|---|---|---|---|---|---|
| 424 | 101 | 280 | 12,523 | 3,208 | 6,923 |
| Protein | Taxonomy | clofarabine (IC50) | gemcitabine (IC50) |
|---|---|---|---|
| Chain A, DEOXYNUCLEOSIDE KINASE | Drosophila melanogaster (fruit fly) | 0.76 | |
| Equilibrative nucleoside transporter 1 | Homo sapiens (human) | 0.19 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 11 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ameral, R; Birkus, G; Cihlar, T; Dzubák, P; Hajdúch, M; Hocek, M; Mackman, R; Naus, P; Pohl, R; Ray, AS; Votruba, I; Wang, T | 1 |
| Benfenati, E; Raska, I; Toropov, AA; Toropova, AP | 1 |
| Birkus, G; Bourderioux, A; Cihlar, T; Dzubák, P; Feng, JY; Hajdúch, M; Hocek, M; Konecný, P; Naus, P; Perlíková, P; Pichová, I; Pohl, R; Ray, AS; Stray, KM; Votruba, I; Wang, T | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Bonnac, L; Clouser, CL; Daly, MB; Kim, B; Landman, SR; Mansky, LM; Patterson, SE; Rawson, JM; Reilly, CS; Roth, ME; Xie, J | 1 |
| Cen, Y; Sauve, AA | 1 |
| Ge, Y; Guo, Y; Qi, W; Wang, G; Xie, C; Xu, X; Zhang, A | 1 |
| Campbell, DO; Czernin, J; Lee, JT; Radu, CG; Satyamurthy, N | 1 |
| Gilbert, KS; Scoggins, JW; Stackhouse, MA; Waud, WR | 1 |
| Andersson, BS; Champlin, RE; Li, Y; Murray, D; Nieto, Y; Qazilbash, MH; Shah, J; Turturro, F; Valdez, BC; Wang, G; Wang, M; Weber, DM | 1 |
| Barrett, AM; Chen, A; Doroshow, JH; Dull, AB; Hollingshead, MG; Kinders, RJ; Kummar, S; Lawrence, SM; Parchment, RE; Wilsker, DF | 1 |
1 review(s) available for clofarabine and gemcitabine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
10 other study(ies) available for clofarabine and gemcitabine
| Article | Year |
|---|---|
6-(Het)aryl-7-deazapurine ribonucleosides as novel potent cytostatic agents.
Topics: Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cytostatic Agents; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Purines; Ribonucleosides; Stereoisomerism; Structure-Activity Relationship | 2010 |
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations.
Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water | 2010 |
Synthesis and significant cytostatic activity of 7-hetaryl-7-deazaadenosines.
Topics: Adenosine Kinase; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cytostatic Agents; Humans; Mice; RNA Polymerase II; Tubercidin | 2011 |
Synergistic reduction of HIV-1 infectivity by 5-azacytidine and inhibitors of ribonucleotide reductase.
Topics: Anti-HIV Agents; Azacitidine; Dose-Response Relationship, Drug; Enzyme Inhibitors; HIV Infections; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Structure; Ribonucleotide Reductases; Structure-Activity Relationship | 2016 |
Efficient syntheses of clofarabine and gemcitabine from 2-deoxyribonolactone.
Topics: Adenine Nucleotides; Antineoplastic Agents; Arabinonucleosides; Chemistry, Organic; Clofarabine; Deoxycytidine; Gemcitabine; Stereoisomerism; Sugar Acids | 2010 |
Synergistic antitumor interactions between gemcitabine and clofarabine in human pancreatic cancer cell lines.
Topics: Adenine Nucleotides; Antineoplastic Agents; Apoptosis; Arabinonucleosides; Cell Line, Tumor; Clofarabine; Deoxycytidine; Drug Synergism; Gemcitabine; Humans; Pancreatic Neoplasms; S Phase Cell Cycle Checkpoints | 2012 |
Stratification of nucleoside analog chemotherapy using 1-(2'-deoxy-2'-18F-fluoro-β-D-arabinofuranosyl)cytosine and 1-(2'-deoxy-2'-18F-fluoro-β-L-arabinofuranosyl)-5-methylcytosine PET.
Topics: Adenine Nucleotides; Animals; Arabinonucleosides; Cell Line, Tumor; Clofarabine; Cytarabine; Cytidine Deaminase; Cytosine; Deoxycytidine; Deoxycytidine Kinase; Fluorine Radioisotopes; Gemcitabine; Gene Expression Regulation, Neoplastic; Leukemia, Lymphoid; Mice; Positron-Emission Tomography; Treatment Outcome | 2012 |
Preclinical combination therapy of clofarabine plus radiation.
Topics: Adenine Nucleotides; Animals; Antineoplastic Agents; Arabinonucleosides; Cell Line, Tumor; Clofarabine; Combined Modality Therapy; Deoxycytidine; Drug Evaluation, Preclinical; Gemcitabine; Humans; Mice; Mice, Nude; Neoplasms, Experimental; Tumor Burden; Xenograft Model Antitumor Assays | 2012 |
Mechanistic studies on the synergistic cytotoxicity of the nucleoside analogs gemcitabine and clofarabine in multiple myeloma: relevance of p53 and its clinical implications.
Topics: Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Base Sequence; Cell Line, Tumor; Clofarabine; Deoxycytidine; DNA Damage; DNA Primers; DNA Repair; Drug Synergism; Gemcitabine; Hematopoietic Stem Cell Transplantation; Humans; Multiple Myeloma; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tumor Suppressor Protein p53 | 2013 |
Evaluation of Pharmacodynamic Responses to Cancer Therapeutic Agents Using DNA Damage Markers.
Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Cell Cycle Proteins; Clofarabine; Colorectal Neoplasms; Deoxycytidine; DNA Damage; DNA Repair; Gemcitabine; HCT116 Cells; Histones; HT29 Cells; Humans; Mice; Mice, Nude; Nuclear Proteins; Rad51 Recombinase; Topotecan; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2019 |