clofarabine has been researched along with etoposide in 26 studies
| Studies (clofarabine) | Trials (clofarabine) | Recent Studies (post-2010) (clofarabine) | Studies (etoposide) | Trials (etoposide) | Recent Studies (post-2010) (etoposide) |
|---|---|---|---|---|---|
| 424 | 101 | 280 | 18,306 | 3,693 | 4,900 |
| Protein | Taxonomy | clofarabine (IC50) | etoposide (IC50) |
|---|---|---|---|
| nuclear receptor coactivator 1 isoform 1 [Homo sapiens] | Homo sapiens (human) | 1.153 | |
| nuclear receptor coactivator 3 isoform a | Homo sapiens (human) | 1.4284 | |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 3.187 | |
| Caspase-3 | Homo sapiens (human) | 1 | |
| DNA topoisomerase 2-beta | Homo sapiens (human) | 0.4299 | |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | 4.18 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (11.54) | 29.6817 |
| 2010's | 20 (76.92) | 24.3611 |
| 2020's | 3 (11.54) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Benfenati, E; Raska, I; Toropov, AA; Toropova, AP | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brown, AW; McGregor, BA; Osswald, MB; Savona, MR | 1 |
| Abichandani, R; Barry, E; Carroll, WL; Chu, R; Cooper, T; Gaynon, P; Hijiya, N; Jeha, S; Kadota, R; Rytting, M; Shen, V; Silverman, L; Steinherz, P; Thomson, B | 1 |
| Barberi, W; Bernardo, ME; Bertaina, A; Giraldi, E; Locatelli, F; Merli, P; Parasole, R; Pession, A; Rizzari, C; Testi, AM; Zecca, M | 1 |
| Abonour, R; Baute, J; Cox, E; Farag, SS; Jones, D; Kane, K; Nelson, RP; Robertson, MJ; Schwartz, JE; Secrest, A; Srivastava, S; Sullivan, C; Wood, LL | 1 |
| Bhojwani, D; Campana, D; Cheng, C; Howard, SC; Inaba, H; Jeha, S; Leung, W; Metzger, ML; Pauley, JL; Pei, D; Pui, CH; Ribeiro, RC; Rubnitz, JE; Sandlund, JT | 1 |
| Barry, E; Borowitz, MJ; Carroll, WL; Cooper, T; Dahl, G; Gaynon, PS; Hijiya, N; Isakoff, MS; Jeha, S; Kadota, R; Maloney, K; Paul, JA; Shen, V; Silverman, LB; Steinherz, PG; Thomson, B; Thottassery, JV | 1 |
| Barisone, E; Bertorello, N; Calvillo, M; De Rossi, G; Dufour, C; Lo Nigro, L; Luciani, M; Messina, C; Miano, M; Micalizzi, C; Parasole, R; Petruzziello, F; Pistorio, A; Putti, MC; Varotto, S; Ziino, O | 1 |
| Arceci, RJ; Barry, E; Hijiya, N | 1 |
| Barba, P; Bueno, J; Calbacho, M; Fernández, P; García-Boyero, R; Gonzalez, J; Martínez-Sánchez, P; Ribera, JM; Sampol, A; Serrano, J | 1 |
| Ahmed, AB; Bruserud, O; Hatfield, KJ; Kittang, AO; Reikvam, H; Sjo, M; Tvedt, TH | 1 |
| Boddy, N; Burrows, F; Pallis, M; Russell, N; Seedhouse, C; Whittall, A | 1 |
| Burke, MJ; Gorman, MF; Gossai, N; Karras, NA; Patel, NJ; Verneris, MR | 1 |
| Abbi, KK; Claxton, DF; Ehmann, WC; Rybka, W | 1 |
| Aoki, T; Arakawa, Y; Hanada, R; Hayashi, M; Koh, K; Kubota, Y; Mori, M; Oyama, R | 1 |
| Baruchel, A; Bertrand, Y; Brethon, B; Cave, H; Galambrun, C; Gandemer, V; Leverger, G; Nelken, B; Plat, G; Rohrlich, P; Schmitt, C; Thomas, C; Vérité, C | 1 |
| Chiang, AK; Ha, SY; Lee, V; Li, CK; Liu, AP | 1 |
| Gerber, JM; Grunwald, MR; Induru, R; McDonnell, MH | 1 |
| Abla, O; Boklan, J; DuBois, SG; Goldberg, J; Hijiya, N; Martin, A; Messinger, Y; Oesterheld, J; Weinstein, J | 1 |
| Choi, J; Coustan-Smith, E; Degar, B; Heym, K; Inaba, H; Klco, J; Lacayo, NJ; McNeer, J; Pounds, S; Pui, CH; Raimondi, SC; Ribeiro, RC; Rubnitz, JE; Schiff, D; Taub, J; Triplett, B; Wang, L; Yeoh, AE | 1 |
| Boddy, AV; Haber, M; Langenhorst, J; Lau, L; Lock, RB; Marshall, GM; Punt, AM; Sia, KCS; Span, M; Sutton, R; Trahair, T; Tyrrell, V; van Maarseveen, E; Venn, N; Xie, J | 1 |
| An, HY; Choi, HJ; Choi, JY; Hong, KT; Kang, HJ; Kim, BK; Shin, HY | 1 |
| Dykes, J; Håkansson, Y; Król, L; Pronk, C; Toporski, J; Turkiewicz, D | 1 |
5 review(s) available for clofarabine and etoposide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
The use of higher dose clofarabine in adults with relapsed acute lymphoblastic leukemia.
Topics: Adenine Nucleotides; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clinical Trials as Topic; Clofarabine; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dexamethasone; Dose-Response Relationship, Drug; Doxorubicin; Drug Evaluation; Etoposide; Fatal Outcome; Filgrastim; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Male; Mitoxantrone; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Recombinant Proteins; Recurrence; Remission Induction; Reoperation; Salvage Therapy; Vidarabine; Vincristine; Young Adult | 2009 |
Clofarabine in pediatric acute leukemia: current findings and issues.
Topics: Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Child; Child, Preschool; Clinical Trials as Topic; Clofarabine; Cyclophosphamide; Cytarabine; Etoposide; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2012 |
High-dose etoposide in allogeneic stem cell transplantation.
Topics: Adenine Nucleotides; Anthracyclines; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Busulfan; Carboplatin; Carmustine; Clinical Trials as Topic; Clofarabine; Cyclophosphamide; Dose Fractionation, Radiation; Drug Administration Schedule; Etoposide; Humans; Ifosfamide; Leukemia; Leukemia, Myeloid, Acute; Lomustine; Mucositis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiotherapy, Adjuvant; Severity of Illness Index; Stem Cell Transplantation; Transplantation Conditioning; Transplantation, Homologous; Whole-Body Irradiation | 2012 |
Cutaneous manifestations in leukemia patients.
Topics: Adenine Nucleotides; Antineoplastic Agents; Arabinonucleosides; Clofarabine; Cytarabine; Dermatomycoses; Etoposide; Humans; Leukemia; Mastocytosis; Niacinamide; Paraneoplastic Syndromes; Phenylurea Compounds; Skin Diseases, Bacterial; Skin Neoplasms; Sorafenib | 2016 |
10 trial(s) available for clofarabine and etoposide
| Article | Year |
|---|---|
A multi-center phase I study of clofarabine, etoposide and cyclophosphamide in combination in pediatric patients with refractory or relapsed acute leukemia.
Topics: Acute Disease; Adenine Nucleotides; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Clofarabine; Cyclophosphamide; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Infant; Leukemia; Leukemia, Myeloid, Acute; Maximum Tolerated Dose; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Salvage Therapy; Treatment Outcome; Young Adult | 2009 |
Clofarabine, cyclophosphamide and etoposide as single-course re-induction therapy for children with refractory/multiple relapsed acute lymphoblastic leukaemia.
Topics: Adenine Nucleotides; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Cyclophosphamide; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Survival Analysis; Treatment Outcome | 2009 |
A phase I trial of high-dose clofarabine, etoposide, and cyclophosphamide and autologous peripheral blood stem cell transplantation in patients with primary refractory and relapsed and refractory non-Hodgkin lymphoma.
Topics: Adenine Nucleotides; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Chemical and Drug Induced Liver Injury; Clofarabine; Combined Modality Therapy; Cyclophosphamide; Etoposide; Female; Filgrastim; Gastrointestinal Diseases; Granulocyte Colony-Stimulating Factor; Hematologic Diseases; Hematopoietic Stem Cell Mobilization; Humans; Lymphoma, Non-Hodgkin; Male; Middle Aged; Peripheral Blood Stem Cell Transplantation; Recombinant Proteins; Recurrence; Salvage Therapy; Transplantation, Autologous; Treatment Outcome | 2011 |
Phase 2 trial of clofarabine in combination with etoposide and cyclophosphamide in pediatric patients with refractory or relapsed acute lymphoblastic leukemia.
Topics: Adenine Nucleotides; Adolescent; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Cyclophosphamide; Etoposide; Female; Humans; Infant; Kaplan-Meier Estimate; Male; Nucleoside Transport Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Risk Factors; RNA, Messenger; Young Adult | 2011 |
Clofarabine, cyclophosphamide and etoposide for the treatment of relapsed or resistant acute leukemia in pediatric patients.
Topics: Acute Disease; Adenine Nucleotides; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Clofarabine; Cyclophosphamide; Drug Administration Schedule; Etoposide; Female; Gastrointestinal Diseases; Humans; Infant; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Recurrence; Remission Induction; Treatment Outcome | 2012 |
Phase I/II study of clofarabine, etoposide, and mitoxantrone in patients with refractory or relapsed acute leukemia.
Topics: Adenine Nucleotides; Adult; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Neoplasm Staging; Recurrence; Remission Induction; Treatment Outcome | 2015 |
A Phase I Study of Clofarabine With Multiagent Chemotherapy in Childhood High Risk Relapse of Acute Lymphoblastic Leukemia (VANDEVOL Study of the French SFCE Acute Leukemia Committee).
Topics: Adenine Nucleotides; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Asparaginase; Child; Child, Preschool; Clofarabine; Dexamethasone; Dose-Response Relationship, Drug; Etoposide; Female; Humans; Male; Maximum Tolerated Dose; Mitoxantrone; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Salvage Therapy; Young Adult | 2016 |
Combination of clofarabine, cyclophosphamide, and etoposide for relapsed or refractory childhood and adolescent acute myeloid leukemia.
Topics: Adenine Nucleotides; Adolescent; Adult; Allografts; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Cyclophosphamide; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Infant; Leukemia, Myeloid, Acute; Male; Survival Rate | 2017 |
Clofarabine Can Replace Anthracyclines and Etoposide in Remission Induction Therapy for Childhood Acute Myeloid Leukemia: The AML08 Multicenter, Randomized Phase III Trial.
Topics: Adolescent; Adult; Anthracyclines; Child; Child, Preschool; Clofarabine; Etoposide; Female; Humans; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Remission Induction; Young Adult | 2019 |
The combination of clofarabine, etoposide, and cyclophosphamide shows limited efficacy as a bridge to transplant for children with refractory acute leukemia: results of a monitored prospective study.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Clofarabine; Cyclophosphamide; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Infant; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Treatment Outcome; Young Adult | 2021 |
11 other study(ies) available for clofarabine and etoposide
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations.
Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Combination chemotherapy with clofarabine, cyclophosphamide, and etoposide in children with refractory or relapsed haematological malignancies.
Topics: Adenine Nucleotides; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Cyclophosphamide; Etoposide; Female; Hematologic Neoplasms; Humans; Infant; Male | 2012 |
Clofarabine-based chemotherapy for relapsed/refractory adult acute lymphoblastic leukemia and lymphoblastic lymphoma. The Spanish experience.
Topics: Adenine Nucleotides; Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cyclophosphamide; Cytarabine; Drug Evaluation; Etoposide; Female; Humans; Male; Middle Aged; Off-Label Use; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Salvage Therapy; Spain; Young Adult | 2012 |
Efficacy of RNA polymerase II inhibitors in targeting dormant leukaemia cells.
Topics: Acute Disease; Adenine Nucleotides; Antineoplastic Agents; Apoptosis; Arabinonucleosides; Azacitidine; Cell Line, Tumor; Cell Survival; Clofarabine; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Etoposide; Flavonoids; Heterocyclic Compounds, 4 or More Rings; Humans; Leukemia, Myeloid; Piperidines; Purines; RNA Polymerase II; RNA, Neoplasm; Roscovitine; Sirolimus; TOR Serine-Threonine Kinases | 2013 |
A clofarabine-based bridging regimen in patients with relapsed ALL and persistent minimal residual disease (MRD).
Topics: Adenine Nucleotides; Adolescent; Antimetabolites, Antineoplastic; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Cyclophosphamide; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Infant; Neoplasm Recurrence, Local; Neoplasm, Residual; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Probability; Remission Induction; Time Factors; Treatment Outcome; Young Adult | 2014 |
Clofarabine-based combination chemotherapy for relapse and refractory childhood acute lymphoblastic leukemia.
Topics: Adenine Nucleotides; Adolescent; Analgesics, Opioid; Antibiotic Prophylaxis; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Cefazolin; Child; Clofarabine; Cyclophosphamide; Etoposide; Fentanyl; Humans; Induction Chemotherapy; Male; Pain; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Shock, Septic; Systemic Inflammatory Response Syndrome; Treatment Outcome | 2014 |
Refractory acute lymphoblastic leukemia in Chinese children: bridging to stem cell transplantation with clofarabine, cyclophosphamide and etoposide.
Topics: Adenine Nucleotides; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Asian People; Child; Child, Preschool; Clofarabine; Cohort Studies; Combined Modality Therapy; Cyclophosphamide; Etoposide; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Young Adult | 2016 |
Optimization of a clofarabine-based drug combination regimen for the preclinical evaluation of pediatric acute lymphoblastic leukemia.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Clofarabine; Cyclophosphamide; Etoposide; Humans; Mice; Precision Medicine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Xenograft Model Antitumor Assays | 2020 |
Combination Therapy With Chemotherapy, Donor Lymphocyte Infusion With Concurrent Blinatumomab in Relapsed/Refractory Acute Precursor B-Lymphoblastic Leukemia.
Topics: Antibodies, Bispecific; Antineoplastic Combined Chemotherapy Protocols; Blood Donors; Clofarabine; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Drug Resistance, Neoplasm; Etoposide; Humans; Infant; Lymphocyte Transfusion; Male; Neoplasm Recurrence, Local; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Retrospective Studies | 2021 |