clofarabine has been researched along with entinostat in 1 studies
| Studies (clofarabine) | Trials (clofarabine) | Recent Studies (post-2010) (clofarabine) | Studies (entinostat) | Trials (entinostat) | Recent Studies (post-2010) (entinostat) |
|---|---|---|---|---|---|
| 424 | 101 | 280 | 557 | 31 | 402 |
| Protein | Taxonomy | clofarabine (IC50) | entinostat (IC50) |
|---|---|---|---|
| Histone deacetylase 3 | Homo sapiens (human) | 1.5547 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.73 | |
| Tissue factor | Homo sapiens (human) | 8 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 3.93 | |
| Histone deacetylase 4 | Homo sapiens (human) | 2.5077 | |
| Histone deacetylase 1 | Homo sapiens (human) | 1.0631 | |
| Histone deacetylase 7 | Homo sapiens (human) | 2.7679 | |
| Histone deacetylase 2 | Homo sapiens (human) | 1.4517 | |
| Polyamine deacetylase HDAC10 | Homo sapiens (human) | 3.1451 | |
| Histone deacetylase 11 | Homo sapiens (human) | 3.3762 | |
| Histone deacetylase 8 | Homo sapiens (human) | 3.5118 | |
| Histone deacetylase 6 | Homo sapiens (human) | 2.9645 | |
| Histone deacetylase 9 | Homo sapiens (human) | 2.9949 | |
| Histone deacetylase 5 | Homo sapiens (human) | 2.7109 | |
| Histone deacetylase | Plasmodium falciparum (malaria parasite P. falciparum) | 0.94 | |
| Nuclear receptor corepressor 2 | Homo sapiens (human) | 1.185 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baer, MR; Blackford, AL; Carraway, HE; Dezern, A; Ghosh, N; Gojo, I; Gore, L; Gore, SD; Greer, J; Karp, JE; Lee, MJ; Lee, S; Levis, MJ; Piekarz, R; Pratz, KW; Sawalha, Y; Smith, BD; Tomita, Y; Trepel, JB; Yuno, A | 1 |
1 trial(s) available for clofarabine and entinostat
| Article | Year |
|---|---|
Phase 1 study of the histone deacetylase inhibitor entinostat plus clofarabine for poor-risk Philadelphia chromosome-negative (newly diagnosed older adults or adults with relapsed refractory disease) acute lymphoblastic leukemia or biphenotypic leukemia.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cell Lineage; Clofarabine; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Histone Deacetylase Inhibitors; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Recurrence, Local; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Pyridines; Salvage Therapy; Young Adult | 2021 |