Compounds > clofarabine
Page last updated: 2024-09-03

clofarabine and deoxycytidine

clofarabine has been researched along with deoxycytidine in 8 studies

Compound Research Comparison

Studies
(clofarabine)		Trials
(clofarabine)		Recent Studies (post-2010)
(clofarabine)		Studies
(deoxycytidine)		Trials
(deoxycytidine)		Recent Studies (post-2010) (deoxycytidine)
42410128018,1604,6528,898

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's0 (0.00)29.6817
2010's6 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bennett, LL; Brockman, RW; Chang, CH; Montgomery, JA; Parker, WB; Rose, LM; Secrist, JA; Shaddix, SC; Shortnacy, AT; White, EL1
Bennett, LL; Hertel, LW; Montgomery, JA; Parker, WB; Rose, LM; Secrist, JA; Shaddix, SC; Shewach, DS1
Cen, Y; Sauve, AA1
Ge, Y; Guo, Y; Qi, W; Wang, G; Xie, C; Xu, X; Zhang, A1
Campbell, DO; Czernin, J; Lee, JT; Radu, CG; Satyamurthy, N1
Gilbert, KS; Scoggins, JW; Stackhouse, MA; Waud, WR1
Andersson, BS; Champlin, RE; Li, Y; Murray, D; Nieto, Y; Qazilbash, MH; Shah, J; Turturro, F; Valdez, BC; Wang, G; Wang, M; Weber, DM1
Barrett, AM; Chen, A; Doroshow, JH; Dull, AB; Hollingshead, MG; Kinders, RJ; Kummar, S; Lawrence, SM; Parchment, RE; Wilsker, DF1

Other Studies

8 other study(ies) available for clofarabine and deoxycytidine

ArticleYear
Effects of 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine on K562 cellular metabolism and the inhibition of human ribonucleotide reductase and DNA polymerases by its 5'-triphosphate.
    Cancer research, 1991, May-01, Volume: 51, Issue:9

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Arabinonucleosides; Cell Division; Clofarabine; Cytidine Triphosphate; Deoxycytidine; DNA; Guanidine; Guanidines; Humans; Nucleic Acid Synthesis Inhibitors; Ribonucleotide Reductases; RNA; Tumor Cells, Cultured

1991
Comparison of the mechanism of cytotoxicity of 2-chloro-9-(2-deoxy-2- fluoro-beta-D-arabinofuranosyl)adenine, 2-chloro-9-(2-deoxy-2-fluoro- beta-D-ribofuranosyl)adenine, and 2-chloro-9-(2-deoxy-2,2-difluoro- beta-D-ribofuranosyl)adenine in CEM cells.
    Molecular pharmacology, 1999, Volume: 55, Issue:3

    Topics: Adenine Nucleotides; Antineoplastic Agents; Arabinonucleosides; Cell Division; Clofarabine; Deoxyadenosines; Deoxycytidine; Deoxycytidine Kinase; DNA; Enzyme Inhibitors; Humans; Macromolecular Substances; Phosphorylation; Substrate Specificity; Tritium; Tumor Cells, Cultured

1999
Efficient syntheses of clofarabine and gemcitabine from 2-deoxyribonolactone.
    Nucleosides, nucleotides & nucleic acids, 2010, Volume: 29, Issue:2

    Topics: Adenine Nucleotides; Antineoplastic Agents; Arabinonucleosides; Chemistry, Organic; Clofarabine; Deoxycytidine; Gemcitabine; Stereoisomerism; Sugar Acids

2010
Synergistic antitumor interactions between gemcitabine and clofarabine in human pancreatic cancer cell lines.
    Molecular medicine reports, 2012, Volume: 5, Issue:3

    Topics: Adenine Nucleotides; Antineoplastic Agents; Apoptosis; Arabinonucleosides; Cell Line, Tumor; Clofarabine; Deoxycytidine; Drug Synergism; Gemcitabine; Humans; Pancreatic Neoplasms; S Phase Cell Cycle Checkpoints

2012
Stratification of nucleoside analog chemotherapy using 1-(2'-deoxy-2'-18F-fluoro-β-D-arabinofuranosyl)cytosine and 1-(2'-deoxy-2'-18F-fluoro-β-L-arabinofuranosyl)-5-methylcytosine PET.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2012, Volume: 53, Issue:2

    Topics: Adenine Nucleotides; Animals; Arabinonucleosides; Cell Line, Tumor; Clofarabine; Cytarabine; Cytidine Deaminase; Cytosine; Deoxycytidine; Deoxycytidine Kinase; Fluorine Radioisotopes; Gemcitabine; Gene Expression Regulation, Neoplastic; Leukemia, Lymphoid; Mice; Positron-Emission Tomography; Treatment Outcome

2012
Preclinical combination therapy of clofarabine plus radiation.
    Nucleosides, nucleotides & nucleic acids, 2012, Volume: 31, Issue:9

    Topics: Adenine Nucleotides; Animals; Antineoplastic Agents; Arabinonucleosides; Cell Line, Tumor; Clofarabine; Combined Modality Therapy; Deoxycytidine; Drug Evaluation, Preclinical; Gemcitabine; Humans; Mice; Mice, Nude; Neoplasms, Experimental; Tumor Burden; Xenograft Model Antitumor Assays

2012
Mechanistic studies on the synergistic cytotoxicity of the nucleoside analogs gemcitabine and clofarabine in multiple myeloma: relevance of p53 and its clinical implications.
    Experimental hematology, 2013, Volume: 41, Issue:8

    Topics: Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Base Sequence; Cell Line, Tumor; Clofarabine; Deoxycytidine; DNA Damage; DNA Primers; DNA Repair; Drug Synergism; Gemcitabine; Hematopoietic Stem Cell Transplantation; Humans; Multiple Myeloma; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tumor Suppressor Protein p53

2013
Evaluation of Pharmacodynamic Responses to Cancer Therapeutic Agents Using DNA Damage Markers.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2019, 05-15, Volume: 25, Issue:10

    Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Cell Cycle Proteins; Clofarabine; Colorectal Neoplasms; Deoxycytidine; DNA Damage; DNA Repair; Gemcitabine; HCT116 Cells; Histones; HT29 Cells; Humans; Mice; Mice, Nude; Nuclear Proteins; Rad51 Recombinase; Topotecan; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2019