clofarabine has been researched along with cimetidine in 4 studies
| Studies (clofarabine) | Trials (clofarabine) | Recent Studies (post-2010) (clofarabine) | Studies (cimetidine) | Trials (cimetidine) | Recent Studies (post-2010) (cimetidine) |
|---|---|---|---|---|---|
| 424 | 101 | 280 | 9,473 | 1,687 | 377 |
| Protein | Taxonomy | clofarabine (IC50) | cimetidine (IC50) |
|---|---|---|---|
| Solute carrier family 22 member 1 | Mus musculus (house mouse) | 0.59 | |
| Solute carrier family 22 member 2 | Mus musculus (house mouse) | 8 | |
| Potassium-transporting ATPase alpha chain 1 | Homo sapiens (human) | 0.82 | |
| Histamine H2 receptor | Homo sapiens (human) | 1.1742 | |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | 1.02 | |
| Potassium-transporting ATPase subunit beta | Homo sapiens (human) | 0.82 | |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | 3.0333 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Ajavon, AD; Bonate, PL; Taft, DR | 1 |
1 review(s) available for clofarabine and cimetidine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
3 other study(ies) available for clofarabine and cimetidine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Renal excretion of clofarabine: assessment of dose-linearity and role of renal transport systems on drug excretion.
Topics: Adenine Nucleotides; Animals; Antineoplastic Agents; Arabinonucleosides; Chromatography, High Pressure Liquid; Cimetidine; Clofarabine; Drug Interactions; Glomerular Filtration Rate; Kidney; Male; Protein Binding; Rats; Rats, Sprague-Dawley | 2010 |