Compounds > clociguanil
Page last updated: 2024-08-25

clociguanil and wr 99210

clociguanil has been researched along with wr 99210 in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Genther, CS; Smith, CS1
Adams, JH; Auliff, AM; Cheng, Q; O'Neil, MT1
Nettleton, MJ; Poyser, RH; Shorter, JH1
Howard, V; Mookherjee, S; Nzila-Mouanda, A; Sibley, CH; Watkins, W1
Adams, JH; Auliff, AM; Balu, B; Chen, N; Cheng, Q; O'Neil, MT1

Other Studies

5 other study(ies) available for clociguanil and wr 99210

ArticleYear
Antifolate studies. Activities of 40 potential antimalarial compounds against sensitive and chlorguanide triazine resistant strains of folate-requiring bacteria and Escherichia coli.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:2

    Topics: Animals; Antimalarials; Bacteria; Drug Resistance, Microbial; Escherichia coli; Folic Acid; Folic Acid Antagonists; Malaria; Mice; Plasmodium berghei; Triazines

1977
Defining the role of mutations in Plasmodium vivax dihydrofolate reductase-thymidylate synthase gene using an episomal Plasmodium falciparum transfection system.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:9

    Topics: Animals; Folic Acid Antagonists; Multienzyme Complexes; Mutation; Parasitic Sensitivity Tests; Plasmodium falciparum; Plasmodium vivax; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Transfection

2010
The cardiovascular effects of two new triazine antimalarials, BRL 50216 (Clociguanil) and BRL 6231.
    Toxicology and applied pharmacology, 1974, Volume: 27, Issue:2

    Topics: Acetylcholine; Animals; Anti-Arrhythmia Agents; Antimalarials; Benzyl Compounds; Blood Pressure; Cardiac Output; Carotid Arteries; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Electrocardiography; Ethers; Femoral Artery; Femoral Vein; Heart Rate; Hemodynamics; Histamine; Isoproterenol; Nictitating Membrane; Norepinephrine; Phentolamine; Reserpine; Respiration; Triazines; Vagus Nerve; Vascular Resistance

1974
Identification and analysis of dihydrofolate reductase alleles from Plasmodium falciparum present at low frequency in polyclonal patient samples.
    The American journal of tropical medicine and hygiene, 1999, Volume: 61, Issue:1

    Topics: Alleles; Animals; Antimalarials; DNA Primers; DNA Restriction Enzymes; DNA, Protozoan; Humans; Inhibitory Concentration 50; Kenya; Malaria, Falciparum; Plasmodium falciparum; Polymerase Chain Reaction; Proguanil; Pyrimethamine; Saccharomyces cerevisiae; Tetrahydrofolate Dehydrogenase; Triazines

1999
Functional analysis of Plasmodium vivax dihydrofolate reductase-thymidylate synthase genes through stable transformation of Plasmodium falciparum.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: Amino Acid Substitution; Antimalarials; Cells, Cultured; Drug Resistance; Erythrocytes; Folic Acid Antagonists; Gene Dosage; Humans; Inhibitory Concentration 50; Mutagenesis, Insertional; Plasmodium falciparum; Plasmodium vivax; Proguanil; Protozoan Proteins; Pyrimethamine; Recombinant Proteins; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Transfection; Triazines

2012