clioquinol has been researched along with curcumin in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (75.00) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, L; Li, W; Li, X; Wang, B; Wang, Y; Wang, Z | 1 |
| Cai, P; Kong, LY; Liu, QH; Wang, XB; Wang, ZM; Wu, JJ; Xu, DQ; Yang, XL | 1 |
| Cai, P; Kong, LY; Li, F; Liu, QH; Wang, J; Wang, XB; Wu, JJ; Yang, XL | 1 |
| Chan, ASC; Feng, X; Hu, J; Huang, L; Li, X; Wang, Z; Yang, X | 1 |
| Liu, P; Liu, ZP; Shi, XL; Wu, JD | 1 |
| Huang, W; Li, Q; Liang, M; Shen, Z; Tang, L; Wang, B; Wang, Q; Zhang, C; Zhang, Z; Zheng, X | 1 |
| Cao, Z; Deng, Y; Liu, Z; Song, Q; Tan, Z; Yang, Z; Yu, G | 1 |
| Jia, CC; Liu, ZP; Wang, XX; Wu, JD; Xie, F; Yan, N; Zeng, YL | 1 |
8 other study(ies) available for clioquinol and curcumin
| Article | Year |
|---|---|
Design, Synthesis, and Evaluation of Orally Available Clioquinol-Moracin M Hybrids as Multitarget-Directed Ligands for Cognitive Improvement in a Rat Model of Neurodegeneration in Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Benzofurans; Clioquinol; Cognition; Cyclic Nucleotide Phosphodiesterases, Type 4; Inflammation; Ligands; Male; Memory; Models, Molecular; Neurons; Neuroprotective Agents; Phosphodiesterase 4 Inhibitors; Protein Aggregates; Rats; Rats, Wistar; Resorcinols | 2015 |
Rational modification of donepezil as multifunctional acetylcholinesterase inhibitors for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Cell Survival; Cholinesterase Inhibitors; Copper; Donepezil; Drug Design; Humans; Indans; Kinetics; Liver; Mice; Models, Molecular; Peptide Fragments; Piperidines; Protein Aggregates; Protein Conformation | 2016 |
Synthesis and pharmacological evaluation of novel chromone derivatives as balanced multifunctional agents against Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Apoptosis; Binding Sites; Blood-Brain Barrier; Chromones; Copper; Humans; Hydrogen Peroxide; Inhibitory Concentration 50; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Protein Structure, Tertiary; Rats; Reactive Oxygen Species; Structure-Activity Relationship | 2017 |
Design, Synthesis, and Evaluation of Orally Bioavailable Quinoline-Indole Derivatives as Innovative Multitarget-Directed Ligands: Promotion of Cell Proliferation in the Adult Murine Hippocampus for the Treatment of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Cell Proliferation; Drug Design; Hippocampus; Humans; Indoles; Ligands; Memory Disorders; Mice; Quinolines | 2018 |
Synthesis and evaluation of novel GSK-3β inhibitors as multifunctional agents against Alzheimer's disease.
Topics: Alzheimer Disease; Amides; Amines; Animals; Antioxidants; Blood-Brain Barrier; Cell Line; Chelating Agents; Drug Design; Glycogen Synthase Kinase 3 beta; Humans; PC12 Cells; Protein Aggregation, Pathological; Protein Kinase Inhibitors; Rats; Structure-Activity Relationship; tau Proteins | 2019 |
Development of the "hidden" multifunctional agents for Alzheimer's disease.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Chelating Agents; Cholinesterase Inhibitors; Drug Design; ERG1 Potassium Channel; Male; Mice; Microsomes, Liver; Molecular Docking Simulation; Molecular Structure; Nootropic Agents; Peptide Fragments; Protein Multimerization; Quinolines; Rats, Sprague-Dawley; Structure-Activity Relationship; Zebrafish | 2019 |
Design, synthesis and evaluation of flurbiprofen-clioquinol hybrids as multitarget-directed ligands against Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Clioquinol; Drug Discovery; Flurbiprofen; Humans; Ligands; Membranes, Artificial; Models, Molecular; Molecular Structure; Protein Conformation; Structure-Activity Relationship | 2020 |
Synthesis and biological evaluation of selective histone deacetylase 6 inhibitors as multifunctional agents against Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Cell Survival; Copper; Dose-Response Relationship, Drug; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Humans; Molecular Structure; Neuroprotective Agents; Peptide Fragments; Structure-Activity Relationship; Tumor Cells, Cultured | 2021 |