clemastine and cimetidine

clemastine has been researched along with cimetidine in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199023 (60.53)18.7374
1990's7 (18.42)18.2507
2000's5 (13.16)29.6817
2010's3 (7.89)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Andersson, RG; Colldahl, H; Lindgren, BR1
Bury, T; Radermecker, M1
Linde, I; Tryba, M; Voshage, G; Zenz, M1
Barth, J; Sahre, EM; Wozel, G1
Gunin, AG1
André, C; André, F; Cavagna, S1
Fairris, GM; Fairris, N1
Nicholson, AN1
Clauss, W; Ring, J; Rothenberger, KH1
Youngchaiyud, U1
Betti, R; Casanueva, FF; Cella, SG; Müller, EE1
Bommer, M; Herz, A; Liebisch, D; Noble, EP1
Jacoby, BG; Wesley, RE1
Bommer, M; Herz, A; Kley, N; Liebisch, D; Noble, E1
Takigawa, M; Tokura, Y; Yamada, M; Yamauchi, T1
Bommer, M; Costa, T; Herz, A; Noble, EP; Sincini, E1
Benedek, K; Gergely, P; Gonzalez-Cabello, R; Láng, I; Nékam, K; Perl, A1
Gergely, P; Láng, I; Nékám, K; Petrányi, G; Török, K1
Gergely, P; Láng, I; Petrányi, G1
Granerus, G; Olafsson, JH; Roupe, G1
Abraham, WM; Ahmed, T; Hartmann, V; Magnussen, H; Oliver, W; Wanner, A1
Dorsch, W; Neuhauser, J; Reimann, HJ1
Nair, MP; Schwartz, SA1
Kerr, JW; Thomson, NC1
Korpás, J; Nosál'ová, G; Strapková, A1
Betti, R; Casanueva, F; Chieli, T; Cocchi, D; Mantegazza, P; Müller, EE1
Heyneman, CA1
Friedl, W; Lamadé, WR; Meeder, PJ; Schmid, B1
Akoev, GN; Filippova, LV; Sherman, NO1
Freund, W; Hausamen, TU; Lipke, J; Löffler, TM1
Kazmierczak, H; Mierzwinski, J; Pawlak-Osinska, K; Piziewicz, A1
Andersson, H; Boman, K; Parö, G; Puistola, U; Ridderheim, M; Rosenberg, P; Sorbe, B1
Behr, J; Herzinger, T; Przybilla, B1

Reviews

2 review(s) available for clemastine and cimetidine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Histamine2-antagonists in allergic disorders.
    The Annals of pharmacotherapy, 1994, Volume: 28, Issue:6

    Topics: Asthma; Chlorpheniramine; Cimetidine; Clemastine; Clinical Trials as Topic; Drug Therapy, Combination; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Hypersensitivity; Male; Nasal Decongestants; Ranitidine; Rhinitis, Allergic, Perennial

1994

Trials

8 trial(s) available for clemastine and cimetidine

ArticleYear
[Histamine release and cardiovascular reactions to implantation of bone cement during total hip replacement].
    Der Anaesthesist, 1991, Volume: 40, Issue:1

    Topics: Aged; Aged, 80 and over; Arrhythmias, Cardiac; Bone Cements; Cimetidine; Clemastine; Female; Hip Prosthesis; Histamine Release; Humans; Hypotension; Male; Middle Aged

1991
[Effectiveness of combination treatment with H1-(Tavegyl) and H2-antagonists (Altramet) in chronic/chronically-recurrent urticaria].
    Dermatologische Monatschrift, 1990, Volume: 176, Issue:11

    Topics: Adult; Chronic Disease; Cimetidine; Clemastine; Double-Blind Method; Female; Humans; Male; Middle Aged; Recurrence; Urticaria

1990
Cimetidine's effect on dermal H1-receptor antagonist tolerance.
    British journal of clinical pharmacology, 1985, Volume: 19, Issue:2

    Topics: Adult; Cimetidine; Clemastine; Clinical Trials as Topic; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Immune Tolerance; Male; Random Allocation; Skin

1985
Prevention of anaphylactoid reactions after radiographic contrast media infusion by combined histamine H1- and H2-receptor antagonists: results of a prospective controlled trial.
    International archives of allergy and applied immunology, 1985, Volume: 78, Issue:1

    Topics: Adolescent; Adult; Aged; Anaphylaxis; Cimetidine; Clemastine; Clinical Trials as Topic; Contrast Media; Female; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Male; Middle Aged; Placebos; Prednisolone; Prospective Studies

1985
Comparison of the efficacy of four antihistamines in chronic urticaria.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1988, Volume: 71, Issue:10

    Topics: Adolescent; Adult; Chlorpheniramine; Chronic Disease; Cimetidine; Clemastine; Double-Blind Method; Drug Combinations; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Middle Aged; Pruritus; Random Allocation; Urticaria

1988
Bone cement implantation syndrome. A prospective randomised trial for use of antihistamine blockade.
    Archives of orthopaedic and trauma surgery, 1995, Volume: 114, Issue:6

    Topics: Bone Cements; Cimetidine; Clemastine; Double-Blind Method; Female; Hip Prosthesis; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Male; Pressure; Prospective Studies; Syndrome

1995
Schedule- and dose-intensified paclitaxel as weekly 1-hour infusion in pretreated solid tumors: results of a phase I/II trial.
    Seminars in oncology, 1996, Volume: 23, Issue:6 Suppl 16

    Topics: Adult; Aged; Anti-Allergic Agents; Antiemetics; Antineoplastic Agents, Phytogenic; Cimetidine; Clemastine; Dexamethasone; Drug Administration Schedule; Female; Histamine H2 Antagonists; Humans; Infusions, Parenteral; Male; Middle Aged; Neoplasms; Ondansetron; Paclitaxel

1996
Randomized trial of single agent paclitaxel given weekly versus every three weeks and with peroral versus intravenous steroid premedication to patients with ovarian cancer previously treated with platinum.
    Acta oncologica (Stockholm, Sweden), 2002, Volume: 41, Issue:5

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cimetidine; Clemastine; Dexamethasone; Disease-Free Survival; Drug Administration Schedule; Drug Hypersensitivity; Drug Resistance, Neoplasm; Female; Hematologic Diseases; Humans; Infusions, Intravenous; Injections, Intravenous; Life Tables; Middle Aged; Muscular Diseases; Nervous System Diseases; Organoplatinum Compounds; Ovarian Neoplasms; Paclitaxel; Premedication; Salvage Therapy; Survival Analysis; Treatment Outcome

2002

Other Studies

28 other study(ies) available for clemastine and cimetidine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Inhibitory effects of imidazolines on histamine liberation from human leukocytes and on tracheal smooth muscle tone.
    Acta pharmacologica et toxicologica, 1978, Volume: 42, Issue:5

    Topics: Animals; Cattle; Cimetidine; Clemastine; Clonidine; Guinea Pigs; Histamine H1 Antagonists; Histamine H2 Antagonists; Histamine Release; Humans; Imidazoles; Leukocytes; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Phentolamine; Phenylephrine; Propranolol; Tolazoline

1978
Role of histamine in the chemotactic deactivation of polymorphonuclear leukocytes following incubation with formylmethionyl peptides.
    International archives of allergy and immunology, 1992, Volume: 97, Issue:2

    Topics: Amine Oxidase (Copper-Containing); Basophils; Calcium; Chemotaxis, Leukocyte; Cimetidine; Clemastine; Dipeptides; Dose-Response Relationship, Drug; Drug Interactions; Histamine; Humans; Immunoglobulin E; Immunoglobulin G; In Vitro Techniques; Leukotriene B4; Magnesium; Neutrophils; Time Factors

1992
[Histamine distribution in the uterine structures of ovariectomized rats administered estradiol, histamine antagonists and an inhibitor of prostaglandin synthesis].
    Arkhiv anatomii, gistologii i embriologii, 1989, Volume: 97, Issue:11

    Topics: Animals; Cimetidine; Clemastine; Estradiol; Female; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histamine Release; Histocytochemistry; Indomethacin; Ovariectomy; Ovary; Prostaglandin Antagonists; Rats; Uterus

1989
Role of histamine in the cell turnover changes associated with experimental gastric ulceration in the mastomys.
    Gastroenterology, 1985, Volume: 88, Issue:2

    Topics: Animals; Cell Division; Cimetidine; Clemastine; Disease Models, Animal; Female; Histamine H1 Antagonists; Histamine Release; Male; Muridae; Promethazine; Stomach Ulcer; Thymidine

1985
Central effects of H1 and H2 antihistamines.
    Aviation, space, and environmental medicine, 1985, Volume: 56, Issue:4

    Topics: Aerospace Medicine; Benzhydryl Compounds; Central Nervous System; Chlorpheniramine; Cimetidine; Clemastine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Phenothiazines; Promethazine; Psychomotor Performance; Ranitidine; Sleep Stages; Structure-Activity Relationship; Terfenadine; Visual Acuity; Visual Perception

1985
Activation of the cholinergic system and growth hormone release in the dog: functional interactions with other neurotransmitters.
    Acta endocrinologica, 1985, Volume: 108, Issue:1

    Topics: Animals; Behavior, Animal; Cimetidine; Clemastine; Diphenhydramine; Dogs; Domperidone; Female; Fenfluramine; Growth Hormone; Male; Metergoline; Naloxone; Phentolamine; Physostigmine; Pimozide; Pizotyline; Propranolol; Radioimmunoassay; Receptors, Cholinergic; Synaptic Transmission

1985
H1-histaminergic activation of catecholamine release by chromaffin cells.
    Biochemical pharmacology, 1988, Jan-15, Volume: 37, Issue:2

    Topics: Adrenal Medulla; Animals; Biological Transport, Active; Calcium; Catecholamines; Cattle; Cells, Cultured; Cimetidine; Clemastine; Histamine; Hormones; Kinetics; Muscarine; Nicotine; Norepinephrine; Ranitidine; Receptors, Histamine; Receptors, Histamine H1

1988
Painful orbital inflammatory lesions and mastocytosis.
    Annals of ophthalmology, 1987, Volume: 19, Issue:4

    Topics: Adolescent; Biopsy; Cimetidine; Clemastine; Combined Modality Therapy; Diphenhydramine; Drug Therapy, Combination; Female; Humans; Mastocytosis; Orbital Diseases; Skin; Ultraviolet Therapy

1987
Histamine affects release and biosynthesis of opioid peptides primarily via H1-receptors in bovine chromaffin cells.
    Journal of neurochemistry, 1987, Volume: 49, Issue:6

    Topics: Adrenal Glands; Animals; Calcium; Cattle; Cells, Cultured; Chromaffin System; Cimetidine; Clemastine; Cobalt; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Gallopamil; Histamine; Histamine Antagonists; Nifedipine; Protein Precursors; Pyrilamine; Ranitidine; Receptors, Histamine; Receptors, Histamine H1; RNA, Messenger

1987
Solar urticaria: a case with good therapeutic response to cimetidine.
    Dermatologica, 1986, Volume: 173, Issue:5

    Topics: Adult; Cimetidine; Clemastine; Female; Humans; Phenothiazines; Photosensitivity Disorders; Sunlight; Urticaria

1986
H1-histaminergic activation stimulates inositol-1-phosphate accumulation in chromaffin cells.
    Biochemical and biophysical research communications, 1986, Mar-13, Volume: 135, Issue:2

    Topics: Adrenal Medulla; Animals; Bradykinin; Carbachol; Cattle; Cimetidine; Clemastine; Histamine; Hydrolysis; In Vitro Techniques; Inositol Phosphates; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Sugar Phosphates; Time Factors

1986
Effect of histamine-receptor blocking on human natural and lectin-dependent cell-mediated cytotoxicity against adherent HEP-2 cells.
    Thymus, 1985, Volume: 7, Issue:2

    Topics: Cell Adhesion; Cell Line; Cimetidine; Clemastine; Concanavalin A; Cytotoxicity, Immunologic; Histamine; Histamine Antagonists; Humans; Immunity, Innate; In Vitro Techniques; Lymphocytes; Pharyngeal Neoplasms

1985
Effect of histamine receptor blocking on human antibody-dependent cell-mediated cytotoxicity.
    Scandinavian journal of immunology, 1981, Volume: 13, Issue:4

    Topics: Animals; Antibody-Dependent Cell Cytotoxicity; Chickens; Cimetidine; Clemastine; Erythrocytes; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Monocytes

1981
Effect of histamine-receptor blocking on human spontaneous lymphocyte-mediated cytotoxicity.
    Scandinavian journal of immunology, 1981, Volume: 14, Issue:5

    Topics: Cimetidine; Clemastine; Cytotoxicity, Immunologic; Histamine H1 Antagonists; Humans; Immunoglobulin Fc Fragments; In Vitro Techniques; Killer Cells, Natural; Lymphocytes; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2

1981
Effect of antihistamins (H1 and H2), cortisone and beta-adrenergic stimulator on murine contact sensitivity and histamine metabolism.
    International archives of allergy and applied immunology, 1983, Volume: 70, Issue:2

    Topics: Adrenergic beta-Agonists; Animals; Cimetidine; Clemastine; Dermatitis, Contact; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Hydrocortisone; Immunization, Passive; Male; Mice; Mice, Inbred CBA; Terbutaline

1983
Histamine receptor blocking effects of cimetidine in the airways.
    Agents and actions, 1983, Volume: 13, Issue:1

    Topics: Airway Resistance; Animals; Carbachol; Cimetidine; Clemastine; Drug Interactions; Female; Guanidines; Histamine; Histamine H2 Antagonists; Injections, Intravenous; Respiratory System; Sheep

1983
Histamine1--histamine2 antagonism: effect of combined clemastine and cimetidine pretreatment on allergen and histamine-induced reactions of the guinea pig lung in vivo and in vitro.
    Agents and actions, 1982, Volume: 12, Issue:1-2

    Topics: Allergens; Animals; Cimetidine; Clemastine; Drug Interactions; Exudates and Transudates; Guanidines; Guinea Pigs; Histamine; Histamine Release; In Vitro Techniques; Lung; Male; Pyrrolidines; Time Factors

1982
Effect of histamine and histamine antagonists on natural and antibody-dependent cellular cytotoxicity of human lymphocytes in vitro.
    Cellular immunology, 1983, Oct-01, Volume: 81, Issue:1

    Topics: Adult; Antibody-Dependent Cell Cytotoxicity; Cell Survival; Cells, Cultured; Cimetidine; Clemastine; Dose-Response Relationship, Drug; Female; Histamine; Humans; Killer Cells, Natural; Lymphocytes; Male; Pyrrolidines; T-Lymphocytes, Regulatory

1983
Effect of inhaled H1 and H2 receptor antagonist in normal and asthmatic subjects.
    Thorax, 1980, Volume: 35, Issue:6

    Topics: Adolescent; Adult; Airway Resistance; Asthma; Cimetidine; Clemastine; Female; Forced Expiratory Volume; Guanidines; Histamine; Humans; Ipratropium; Male; Methacholine Compounds; Middle Aged; Pyrrolidines

1980
[Experimental cough and histamine receptor blockers].
    Bratislavske lekarske listy, 1983, Volume: 79, Issue:3

    Topics: Animals; Antitussive Agents; Cats; Cimetidine; Clemastine; Cough; Female; Guanidines; Male; Pyrrolidines

1983
Proof for histaminergic but not for adrenergic involvement in the growth hormone-releasing effect of an enkephalin analog in the dog.
    Endocrinology, 1981, Volume: 108, Issue:1

    Topics: Animals; Cimetidine; Clemastine; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Diphenhydramine; Dogs; Endorphins; Enkephalins; Female; Glucose; Growth Hormone; Histamine; Male; Phentolamine; Propranolol; Sympathetic Nervous System

1981
[The effect of the mast-cell mediators histamine and prostaglandins on the afferent nerve fibers of the small intestine in the cat].
    Fiziologicheskii zhurnal imeni I.M. Sechenova, 1996, Volume: 82, Issue:2

    Topics: Afferent Pathways; Animals; Cats; Cimetidine; Clemastine; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Intestine, Small; Mast Cells; Membrane Potentials; Mesentery; Neurotransmitter Agents; Prostaglandin D2

1996
The effect of betahistine on vestibular habituation: comparison of rotatory and sway habituation training.
    Acta oto-laryngologica, 2001, Volume: 121, Issue:5

    Topics: Animals; Betahistine; Cimetidine; Clemastine; Columbidae; Habituation, Psychophysiologic; Histamine Agonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Motion Sickness; Nystagmus, Pathologic; Posture; Receptors, Histamine H1; Receptors, Histamine H2; Teaching; Vestibule, Labyrinth

2001
[Tolerance induction in anaphylaxis to carboplatin].
    Deutsche medizinische Wochenschrift (1946), 2003, Jul-25, Volume: 128, Issue:30

    Topics: Abdominal Neoplasms; Aged; Anaphylaxis; Antineoplastic Agents; Carboplatin; Chemotherapy, Adjuvant; Cimetidine; Clemastine; Combined Modality Therapy; Desensitization, Immunologic; Dexamethasone; Drug Hypersensitivity; Drug Therapy, Combination; Female; Humans; Indoles; Infusions, Intravenous; Lung Neoplasms; Ovarian Neoplasms; Premedication; Tropisetron

2003