clay and allyl-isothiocyanate

Allyl isothiocyanate (AITC) is a highly volatile organic compound that is a potential antibacterial agent against food spoilage bacteria. Naturally formed halloysite nanotubes (HNTs) have a length of 1 μm and diameter ranging from 10 to 50 nm. The biocompatibility of HNT allows safe release of drugs to bacterial cells at a relatively low concentration compared to other systems. We encapsulated AITC inside HNTs that were then coated with sodium polyacrylate (PA). The HNT-AITC-PA nanocomposites (NCs) were characterized by Fourier-transform infrared spectroscopy, thermal gravimetric, X-ray diffraction, scanning electron microscopy, and transmission electron microscopy analyses. In vitro antibacterial activity was evaluated against gram positive (Staphylococcus aureus) and gram negative (Escherichia coli) bacteria capable of food spoilage. HNT-AITC-PA NCs effectively inhibited the growth of both bacteria. The activity was pronounced against E. coli at 100 μg/mL, with concentrations of 25 μg/mL and 200 μg/mL reducing the viable cell population by 41% and 96%, respectively. Thus, HNT-AITC-PA NCs are a novel and promising material against food spoilage bacteria for use in active antibacterial food packaging.

Topics: Acrylates; Anti-Bacterial Agents; Clay; Dynamic Light Scattering; Escherichia coli; Food Preservation; Isothiocyanates; Microbial Sensitivity Tests; Nanocomposites; Nanotubes; Particle Size; Spectroscopy, Fourier Transform Infrared