clavulanic acid has been researched along with penicillanic acid in 154 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 49 (31.82) | 18.7374 |
| 1990's | 58 (37.66) | 18.2507 |
| 2000's | 29 (18.83) | 29.6817 |
| 2010's | 18 (11.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bonomo, RA; Currie-McCumber, C; Shlaes, DM | 1 |
| Hedberg, M; Lindqvist, L; Nord, CE; Tunér, K | 2 |
| Aspinall, S; Corkill, JE; Hart, CA; McLennan, AG | 1 |
| Kunii, O; Miyashita, T; Ono, Y | 1 |
| Cullmann, W | 2 |
| Akova, M; Livermore, DM; Yang, Y | 1 |
| Kempers, J; MacLaren, DM | 1 |
| Acar, JF; Coutrot, A; Ferré, B; Gutmann, L; Kitzis, MD | 1 |
| Jacobus, NV; Kuck, NA; Petersen, PJ; Testa, RT; Weiss, WJ | 1 |
| Knap, AK; Pratt, RF | 1 |
| Adachi, K; Ueda, S; Watanabe, M; Yamabe, S | 1 |
| Chin, NX; McElrath, MJ; Neu, HC | 1 |
| Moosdeen, F; Williams, J; Yamabe, S | 1 |
| Arita, T; Iseki, K; Ishizawa, T; Kumamoto, Y; Miyazaki, K; Sakai, S | 1 |
| Conner, CS | 1 |
| Grimont, PA; Hornstein, MJ; Jupeau, AM; Philippon, AM; Scavizzi, MR | 1 |
| Chapman, M; Colley, N; Houang, ET | 1 |
| Scorneaux, B; Van der Auwera, P | 1 |
| Barry, AL; Jones, RN; Packer, RR | 1 |
| Rice, RJ; Thompson, SE | 1 |
| Aldridge, KE; Marier, RL; Sanders, CV | 1 |
| McDougal, LK; Thornsberry, C | 1 |
| Aronoff, SC; Jacobs, MR; Johenning, S; Shlaes, DM; Yamabe, S | 1 |
| Guibourdenche, M; Philippon, A; Riou, JY; Sotolongo, F | 1 |
| Neu, HC | 1 |
| Aronoff, SC; Jacobs, MR; Johenning, S; Yamabe, S | 2 |
| Aronoff, SC; Jacobs, MR; Labrozzi, PH; Yamabe, S | 1 |
| Appelbaum, PC; Jacobs, MR; Spangler, SK; Yamabe, S | 1 |
| Eggleston, M; Parker, RH | 1 |
| Ohkawa, M | 1 |
| Cynamon, MH; Sorg, TB | 1 |
| Houben, AW; Stobberingh, EE; van Boven, CP | 1 |
| Cundy, KR; Fekete, T; McGowen, J | 1 |
| Ito, T; Tamura, M | 1 |
| Binder, S; Cullmann, W; Stieglitz, M | 1 |
| Hall, TW; Ishida, N; Maiti, SN; Micetich, RG; Nakai, A; Ogawa, K; Spevak, P; Tanaka, M; Yamabe, S; Yamazaki, T | 1 |
| Fu, KP; Grace, ME; Gregory, FJ; Hung, PP | 1 |
| Bodey, GP; Bolivar, R; Weaver, SS | 1 |
| Brenner, DG; Knowles, JR | 2 |
| Calderwood, SB; Gardella, A; Jacoby, GA; Moellering, RC; Philippon, AM | 1 |
| Belasco, JG; Charnas, RL; Fisher, J; Khosla, S; Knowles, JR | 1 |
| Andrews, JM; Bedford, KA; Wise, R | 1 |
| Fu, KP; Neu, HC | 2 |
| Andrews, JM; Patel, N; Wise, R | 1 |
| Crast, LB; Gottstein, WJ; Graham, RG; Haynes, UJ; McGregor, DN | 1 |
| Frère, JM; Ghuysen, JM; Kelly, JA; Klein, D | 1 |
| Li, JT; Moosdeen, F; Williams, JD | 1 |
| Baumgärtner, M; Wundt, W | 1 |
| Ullmann, U | 1 |
| Fleck, WF; Heyn, B; Schröer, HP | 1 |
| Baumgärtner, M; Müller, HP; Wundt, W | 1 |
| Baumgärtner, M | 1 |
| Arakawa, Y; Horii, T; Ito, H; Ohsuka, S; Ohta, M | 1 |
| File, TM; Tan, JS | 1 |
| Duval, J; Leclercq, R | 1 |
| Jones, R; Satishchandran, V; Shapiro, T; Suh, B; Truant, AL | 1 |
| Chang, SC; Hsieh, WC; Luh, KT | 1 |
| Amyes, SG; London, N; Stobberingh, E; Thomson, CJ | 1 |
| Harris, EB; Hastings, RC; Prabhakaran, K; Randhawa, B | 1 |
| Fastrez, J; Marchand-Brynaert, J; Vanwetswinkel, S | 1 |
| Cramp, R; Knowles, DJ; Payne, DJ; Winstanley, DJ | 1 |
| Aldridge, KE | 1 |
| Alós, JI; Gómez-Garcés, JL; Mateos, MV | 1 |
| Baquero, F; Reig, M | 1 |
| Edelstein, MA; Edelstein, PH | 1 |
| Duchateau, V; Husson, M; Kinzig, M; Lambert, C; Sörgel, F; Van der Auwera, P | 1 |
| Alos, I; Baquero, F; Baquero, MR; Blazquez, J; Canton, R | 1 |
| Inoue, E; Mitsuhashi, S; Muratani, T; Nakane, T; Yokota, E | 1 |
| Alarcón, MA; Campos, M; González, H; Sánchez, R | 1 |
| Jin, YF; Piddock, LJ; Turner, HL | 1 |
| Bush, K; Lee, VJ; Macalintal, C; Rasmussen, BA; Yang, Y | 1 |
| Barry, A; Fuchs, P; Gerlach, E; Hardy, D; McLaughlin, J; Pfaller, M | 1 |
| Gaudreau, C; Lachance, N; Lamothe, F; Turgeon, F | 1 |
| Amyes, SG; Thomson, CJ | 1 |
| Amicosante, G; Franceschini, N; Oratore, A; Perilli, M; Segatore, B; Setacci, D | 1 |
| Labia, R; Mariotte-Boyer, S; Nicolas-Chanoine, MH | 1 |
| Aplin, RT; Brown, RP; Schofield, CJ | 1 |
| Alonso, JM; Fournier, JL; Jacolot, AC; Petitjean, OJ; Ramisse, F; Scavizzi, MR; Szatanik, M | 1 |
| Alós, JI; Balas, D; Cogollos, R; Gomez-Graces, JL; Tajada, P | 1 |
| Greenwood, D | 1 |
| Livermore, DM; Yuan, M | 1 |
| Knapp, CC; Ludwig, MD; Pohlman, JK; Washington, JA | 1 |
| Klepser, ME; Marangos, MN; Nicolau, DP; Nightingale, CH; Quintiliani, R; Zhu, Z | 1 |
| Blumer, JL; Bonafede, ME | 1 |
| Bonomo, RA; Rudin, SA; Shlaes, DM | 1 |
| Hanaki, H; Nagayama, A; Nomura, S | 1 |
| Basu, D; Basu, J; Narayankumar, DV; Van Beeumen, J | 1 |
| Constantoulaki, S; Paniara, O; Platsouka, E; Zissis, NP | 1 |
| Barthélémy, M; Chaibi, EB; Farzaneh, S; Labia, R; Péduzzi, J; Sirot, D | 1 |
| Calcagno, ML; Danelon, G; Gutkind, G; Mascaretti, O; Mata, EG; Power, P; Radice, M | 1 |
| Amicosante, G; Cornaglia, G; Franceschini, N; Mazzariol, A; Perilli, M; Segatore, B; Setacci, D | 1 |
| Anderson, V; Bonomo, RA; Knox, JR; Lin, S; Rudin, SD; Shlaes, DM; Thomas, M | 1 |
| Jarlier, V | 1 |
| Kim, KH; Park, KW; Yim, CB | 1 |
| de Seny, D; Frere, JM; Galleni, M; Laraki, N; Llabres, G; Prosperi-Meys, C; Soto, RP; Valladares, MH | 1 |
| de la Pena, A; Derendorf, H | 1 |
| Gardner, VM; Lister, PD; Sanders, CC | 1 |
| Giakkoupi, P; Legakis, NJ; Tzelepi, E; Tzouvelekis, LS | 1 |
| Betriu, C; Gómez, M; Palau, ML; Picazo, JJ; Sánchez, A | 1 |
| Degnan, BA; Farmer, TH; Payne, DJ | 1 |
| Kotra, LP; Levesque, RC; Mobashery, S; Sanschagrin, F; Therrien, C | 1 |
| Miranda, E; Sader, HS; Sejas, L; Tosin, I | 1 |
| Levesque, RC; Palzkill, T; Sanschagrin, F; Savoie, A; Voyer, N | 1 |
| Lister, PD | 1 |
| Bonnaure-Mallet, M; Buffet, A; Cormier, M; David, S; Dupuy, C; Jolivet-Gougeon, A; Sixou, JL | 1 |
| Amicosante, G; Belloni, R; Bianchi, C; Lombardi, G; Luzzaro, F; Perilli, M; Toniolo, A; Zollo, A | 1 |
| Chen, Y; Gao, L; Hou, F; Li, J | 1 |
| Niki, Y | 1 |
| Mealey, KL | 1 |
| Bukowski, K; Jakubczak, A; Wolska, MK | 1 |
| Chang, NY; Lim, C; Lin, YL | 1 |
| Nakano, R; Okamoto, R | 1 |
| Anderson, VE; Bethel, CR; Bonomo, RA; Helfand, MS; Hujer, AM; Hujer, KM | 1 |
| Fosse, T; Giraud-Morin, C; Madinier, I | 1 |
| Bonomo, RA; Carey, MP; Carey, PR; Helfand, MS; Hujer, AM; Totir, MA | 1 |
| Beharry, Z; Buynak, JD; Chen, H; Gadhachanda, VR; Palzkill, T | 1 |
| Higgins, PG; Seifert, H; Stefanik, D; Wisplinghoff, H | 1 |
| Høiby, N; Walther-Rasmussen, J | 1 |
| Bonnefoy, A; Delachaume, C; Dupuis-Hamelin, C; Fairley, M; Guitton, M; Lampilas, M; Seys, C; Stachyra, T; Steier, V | 1 |
| Ashkenazi, S; Bishara, J; Lev, B; Levy, I; Livne, G; Ofir, O; Pitlik, S; Samra, Z | 1 |
| Bonomo, RA; Carey, MP; Carey, PR; Helfand, MS; Padayatti, PS; Totir, MA; van den Akker, F | 1 |
| Nord, CE | 1 |
| Broide, E; Raveh, D; Rudensky, B; Yinnon, AM | 1 |
| Bonomo, RA; Buynak, JD; Carey, PR; Helfand, MS; Taracila, MA; Totir, MA; van den Akker, F | 1 |
| Bonomo, RA; Buynak, JD; Carey, MP; Carey, PR; Helfand, MS; Sheri, A; Totir, MA | 1 |
| Correia, A; Domingues, MR; Domingues, P; Fonseca, F; Henriques, I; Saavedra, MJ; Samyn, B; Sarmento, AC; van Beeumen, J | 1 |
| Anuradha, K; Lakshmi, V; Sailaja, VV; Satheesh, T; Umabala, P | 1 |
| Buynak, JD; Carey, PR; Kalp, M; Totir, MA | 1 |
| Bleeker-Rovers, CP; Koopman, M; Mannaerts, L; Punt, CJ; van Herpen, CM | 1 |
| Albertí, S; Juan, C; Mulet, X; Oliver, A; Pérez, JL; Zamorano, L | 1 |
| Bethel, CR; Bonomo, RA; Distler, AM; Kasuboski, C; Papp-Wallace, KM; Taracila, M | 1 |
| Bonomo, RA; Distler, AM; Endimiani, A; Hornick, JM; Hujer, AM; Hujer, KM; Papp-Wallace, KM; Taracila, M | 1 |
| Bonnin, RA; Lecuyer, H; Nordmann, P; Poirel, L; Potron, A; Zahar, JR | 1 |
| Bethel, CR; Bonomo, RA; Drawz, SM; Ke, W; Ori, C; Prati, F; Sampson, JM; van den Akker, F | 1 |
| Bethel, CR; Bonnet, R; Bonomo, RA; Distler, AM; Endimiani, A; Hujer, AM; Hujer, KM; Papp-Wallace, K; Shyr, T; Taracila, M; Thomson, JM | 1 |
| Baquero, F; Cantón, R; Galán, JC; Novais, A; Ripoll, A; Rodríguez-Domínguez, MJ; Turrientes, MC | 1 |
| Antunes, NT; Frase, H; Toth, M; Vakulenko, SB; Vakulenko, V | 1 |
| Kasap, M; Torol, S | 1 |
| Holzgrabe, U | 1 |
| Bethel, CR; Bonomo, RA; Carey, PR; de Boer, PA; Heidari Torkabadi, H; Papp-Wallace, KM | 1 |
| Beceiro, A; Bou, G; Galleni, M; García, P; Gómez-Bertomeu, F; González-López, JJ; Kerff, F; Larrosa, N; Méndez, JA; Miró, E; Navarro, F; Oliver, A; Pérez-Llarena, FJ; Zamorano, L | 1 |
| Abbas, S; Dortet, L; Nordmann, P; Oueslati, S; Poirel, L | 1 |
| Botes, J; Boutlis, CS; Glasgow, AL; Jones, SL; Riordan, JW | 1 |
| Boyd, D; Carpenter, M; Desruisseau, A; Janecko, N; Mangat, CS; Martz, SL; Mulvey, MR; Reid-Smith, RJ | 1 |
| Baumert, P; Feihl, S; Gastmeier, P; Gebhardt, F; Gölz, H; Hamprecht, A; Kern, WV; Knobloch, J; Kola, A; Mischnik, A; Obermann, B; Peter, S; Querbach, C; Rohde, A; Seifert, H; Tacconelli, E; Willmann, M | 1 |
| Chen, Y; Guo, P; Yu, G; Yue, C | 1 |
| Ledger, TS | 1 |
| Chong, XM; Hu, CQ; Li, J; Wang, C; Wang, LX; Wang, Y; Yao, SC | 1 |
14 review(s) available for clavulanic acid and penicillanic acid
| Article | Year |
|---|---|
Treatment of uncomplicated infections due to Neisseria gonorrhoeae. A review of clinical efficacy and in vitro susceptibility studies from 1982 through 1985.
Topics: Cephalosporins; Chlamydia Infections; Clavulanic Acid; Clavulanic Acids; Female; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Penicillanic Acid; Penicillin Resistance; Penicillins; Pharyngeal Diseases; Quinolines; Spectinomycin; Sulbactam; Syphilis; Tetracycline | 1986 |
The role of beta-lactamase inhibitors in chemotherapy.
Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Chemical Phenomena; Chemistry; Clavulanic Acid; Clavulanic Acids; Gram-Negative Bacteria; Humans; Lactams; Penicillanic Acid; Sulfones | 1985 |
Beta-lactamase inhibitors: another approach to overcoming antimicrobial resistance.
Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Humans; Kinetics; Penicillanic Acid; Penicillin Resistance; Penicillins; Sulbactam; Ticarcillin | 1987 |
[Clinical application of beta-lactamase inhibitors on urinary tract infections].
Topics: Anti-Bacterial Agents; Bacteria; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Humans; Penicillanic Acid; Sulbactam; Urinary Tract Infections | 1986 |
[Refractory respiratory tract infections. 7. Trends in the development of new chemotherapeutic agents for respiratory tract infections. c. Combinations of beta-lactam antibiotics and beta-lactamases inhibitors].
Topics: Amoxicillin; Ampicillin; beta-Lactamase Inhibitors; Cefoperazone; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Humans; Penicillanic Acid; Penicillins; Respiratory Tract Infections; Sulbactam; Ticarcillin | 1987 |
[Beta lactamase inhibitors, a new start of antibiotic therapy].
Topics: beta-Lactamase Inhibitors; beta-Lactams; Clavulanic Acid; Drug Resistance, Microbial; Humans; Kinetics; Penicillanic Acid; Sulbactam | 1982 |
Efficacy and safety of piperacillin/tazobactam in skin and soft tissue infections.
Topics: Bacterial Infections; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Necrosis; Penicillanic Acid; Piperacillin; Skin Diseases, Bacterial; Soft Tissue Infections; Tazobactam; Ticarcillin | 1994 |
Role of newer broad-spectrum beta-lactam and fluoroquinolone antibiotics in children.
Topics: Adolescent; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Carbapenems; Cephalosporins; Child; Child, Preschool; Clavulanic Acid; Clavulanic Acids; Drug Interactions; Drug Resistance, Microbial; Drug Therapy, Combination; Enzyme Inhibitors; Fluoroquinolones; Humans; Molecular Structure; Penicillanic Acid; Penicillins; Piperacillin; Tazobactam; Ticarcillin | 1996 |
Pharmacokinetic properties of beta-lactamase inhibitors.
Topics: Absorption; Aging; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Biological Availability; Clavulanic Acid; Drug Synergism; Enzyme Inhibitors; Half-Life; Humans; Kidney Diseases; Penicillanic Acid; Sulbactam; Tazobactam | 1999 |
Beta-lactamase inhibitor combinations with extended-spectrum penicillins: factors influencing antibacterial activity against enterobacteriaceae and Pseudomonas aeruginosa.
Topics: beta-Lactamases; Clavulanic Acid; Drug Therapy, Combination; Enterobacteriaceae; Enzyme Inhibitors; Penicillanic Acid; Penicillin Resistance; Piperacillin; Pseudomonas aeruginosa; Tazobactam; Ticarcillin | 2000 |
[Fundamental and clinical studies on beta-lactamase inhibitors].
Topics: Adult; Anti-Bacterial Agents; Bacterial Infections; beta-Lactamase Inhibitors; Clavulanic Acid; Drug Therapy, Combination; Enzyme Inhibitors; Humans; Penicillanic Acid; Piperacillin; Sulbactam; Tazobactam | 2001 |
Penicillins and beta-lactamase inhibitor combinations.
Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; beta-Lactamase Inhibitors; Clavulanic Acid; Drug Resistance, Microbial; Drug Therapy, Combination; Enzyme Inhibitors; Penicillanic Acid; Penicillins; Sulbactam; Tazobactam | 2001 |
[beta-Lactamase-inhibitor combinations].
Topics: Bacteria; beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Drug Design; Drug Resistance, Bacterial; Drug Therapy, Combination; Humans; Penicillanic Acid; Penicillins; Sulbactam; Tazobactam | 2003 |
Cefotaximases (CTX-M-ases), an expanding family of extended-spectrum beta-lactamases.
Topics: beta-Lactamases; Cefotaxime; Cephalosporins; Clavulanic Acid; Drug Resistance, Bacterial; Enterobacteriaceae; Enzyme Inhibitors; Gene Transfer, Horizontal; Monobactams; Penicillanic Acid; Penicillins; Phylogeny; Sulbactam; Tazobactam | 2004 |
2 trial(s) available for clavulanic acid and penicillanic acid
| Article | Year |
|---|---|
Comparison of the bactericidal activities of piperacillin-tazobactam, ticarcillin-clavulanate, and ampicillin-sulbactam against clinical isolates of Bacteroides fragilis, Enterococcus faecalis, Escherichia coli, and Pseudomonas aeruginosa.
Topics: Adult; Ampicillin; Bacteroides fragilis; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Cross-Over Studies; Drug Therapy, Combination; Enterococcus faecalis; Escherichia coli; Female; Humans; Male; Penicillanic Acid; Piperacillin; Pseudomonas aeruginosa; Serum Bactericidal Test; Sulbactam; Tazobactam; Ticarcillin | 1997 |
A randomized controlled clinical trial on piperacillin/tazobactam versus ticarcillin/clavulanic acid for the treatment of bacterial infections.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Clavulanic Acid; Drug Therapy, Combination; Enzyme Inhibitors; Escherichia coli Infections; Female; Humans; Male; Penicillanic Acid; Penicillins; Piperacillin; Pneumonia; Respiratory Tract Infections; Tazobactam; Ticarcillin; Urinary Tract Infections | 1998 |
138 other study(ies) available for clavulanic acid and penicillanic acid
| Article | Year |
|---|---|
OHIO-1 beta-lactamase resistant to mechanism-based inactivators.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Base Sequence; beta-Lactamases; Clavulanic Acid; Clavulanic Acids; Drug Resistance, Microbial; Escherichia coli; Molecular Sequence Data; Mutation; Penicillanic Acid; Plasmids; Sequence Homology, Nucleic Acid; Sulbactam; Tazobactam | 1992 |
Effect of clavulanic acid, sulbactam and tazobactam on three different beta-lactamases from Bacteroides uniformis, Clostridium butyricum and Fusobacterium nucleatum.
Topics: Bacteroides; beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Clavulanic Acids; Clostridium; Fusobacterium nucleatum; Penicillanic Acid; Sulbactam; Tazobactam | 1992 |
Effect of beta-lactamase inhibitors on beta-lactamases from anaerobic bacteria.
Topics: Bacteria, Anaerobic; Bacteroides; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Clostridium; Fusobacterium nucleatum; Penicillanic Acid; Sulbactam; Tazobactam | 1992 |
Characterization of a beta-lactamase produced by Pseudomonas paucimobilis.
Topics: beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Chromosomes, Bacterial; Clavulanic Acid; Clavulanic Acids; Drug Resistance, Microbial; Molecular Weight; Penicillanic Acid; Penicillin Resistance; Penicillins; Pseudomonas; Sulbactam; Tazobactam | 1991 |
[Chemical structure, anti-bacterial activity and pharmacokinetics of penicillins].
Topics: beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Humans; Penicillanic Acid; Penicillin Resistance; Penicillins; Piperacillin; Pseudomonas aeruginosa; Tazobactam; Ticarcillin | 1991 |
Beta-lactamase inhibitors: relation between kinetic data and in-vitro synergism studies.
Topics: beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Drug Synergism; Enterobacter cloacae; Escherichia coli; Klebsiella; Penicillanic Acid; Piperacillin; Proteus vulgaris; Pseudomonas aeruginosa; Staphylococcus aureus; Sulbactam; Tazobactam | 1991 |
Interactions of tazobactam and clavulanate with inducibly- and constitutively-expressed Class I beta-lactamases.
Topics: Bacteria; beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Clavulanic Acids; Enzyme Induction; Half-Life; Kinetics; Penicillanic Acid; Piperacillin; Tazobactam; Ticarcillin | 1990 |
Interaction of beta-lactamase inhibitors with various beta-lactamases.
Topics: beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Clavulanic Acids; Enterobacter; Escherichia coli; Humans; Klebsiella; Penicillanic Acid; Plasmids; Proteus vulgaris; Staphylococcus aureus; Sulbactam; Tazobactam | 1990 |
Piperacillin/tazobactam and ticarcillin/clavulanic acid against resistant Enterobacteriaceae.
Topics: beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Drug Resistance, Microbial; Drug Therapy, Combination; Enterobacteriaceae; Hydrogen-Ion Concentration; Penicillanic Acid; Piperacillin; Tazobactam; Ticarcillin | 1990 |
In vitro activity of combinations of beta-lactam antibiotics with beta-lactamase inhibitors against cephalosporinase-producing bacteria.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Cefotaxime; Cephalosporinase; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Drug Interactions; Drug Resistance, Microbial; Enterobacteriaceae; Enzyme Induction; Humans; Isoelectric Focusing; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Pseudomonas aeruginosa; Sulbactam; Tazobactam; Ticarcillin | 1989 |
Comparative in vitro and in vivo activities of piperacillin combined with the beta-lactamase inhibitors tazobactam, clavulanic acid, and sulbactam.
Topics: Animals; Bacteria; Bacterial Infections; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Drug Therapy, Combination; Female; Mice; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Sulbactam; Tazobactam | 1989 |
Inactivation of the thiol RTEM-1 beta-lactamase by 6-beta-bromopenicillanic acid. Identity of the primary active-site nucleophile.
Topics: beta-Lactamase Inhibitors; beta-Lactamases; Binding Sites; Chemical Phenomena; Chemistry; Clavulanic Acid; Clavulanic Acids; Kinetics; Penicillanic Acid; Spectrophotometry | 1987 |
The effects of three beta-lactamase inhibitors: YTR830H, sulbactam and clavulanic acid on the growth of human cells in culture.
Topics: beta-Lactamase Inhibitors; Cell Division; Cells, Cultured; Clavulanic Acid; Clavulanic Acids; Humans; Penicillanic Acid; Sulbactam; Tazobactam | 1987 |
Beta-lactamase inhibition by acetylmethylene penicillanic acid compared to that of clavulanate and sulbactam.
Topics: Bacteria; beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Clavulanic Acids; Drug Resistance, Microbial; Drug Synergism; Penicillanic Acid; Sulbactam | 1988 |
The activity of a sulphone beta-lactamase inhibitor, YTR 830.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Drug Resistance, Microbial; Enterobacteriaceae; Microbial Sensitivity Tests; Penicillanic Acid; R Factors; Sulbactam; Tazobactam | 1987 |
Effect of clavulanic acid on inactivated amoxicillin excretion in urinary tract infection.
Topics: Administration, Oral; Adult; Aged; Amoxicillin; beta-Lactamases; Clavulanic Acid; Clavulanic Acids; Drug Interactions; Humans; Middle Aged; Penicillanic Acid; Penicillinase; Urinary Tract Infections | 1985 |
beta-Lactamase inhibitors.
Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Bacterial Infections; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Humans; Penicillanic Acid; Sulbactam | 1985 |
In vitro susceptibilities of 126 clinical isolates of Yersinia enterocolitica to 21 beta-lactam antibiotics.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Clavulanic Acids; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Sulbactam; Yersinia enterocolitica | 1985 |
Penetration of sulbactam-ampicillin and clavulanic acid-amoxicillin into the pelvic peritoneum.
Topics: Adult; Amoxicillin; Ampicillin; Ascitic Fluid; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Female; Humans; Injections, Intravenous; Kinetics; Middle Aged; Pelvis; Penicillanic Acid; Peritoneum; Sulbactam | 1985 |
In vitro susceptibility of Campylobacter jejuni to 27 antimicrobial agents and various combinations of beta-lactams with clavulanic acid or sulbactam.
Topics: Anti-Bacterial Agents; Campylobacter fetus; Clavulanic Acid; Clavulanic Acids; Microbial Sensitivity Tests; Penicillanic Acid; Sulbactam | 1985 |
In-vitro susceptibility of the Bacteroides fragilis group to cefoperazone, ampicillin, ticarcillin and amoxycillin combined with beta-lactamase inhibitors.
Topics: Amoxicillin; Ampicillin; Bacteroides fragilis; beta-Lactamase Inhibitors; beta-Lactamases; Cefoperazone; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Penicillanic Acid; Penicillins; Sulbactam; Ticarcillin | 1986 |
Variation in the potentiation of beta-lactam antibiotic activity by clavulanic acid and sulbactam against multiply antibiotic-resistant bacteria.
Topics: Anti-Bacterial Agents; Bacteria; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Drug Resistance, Microbial; Drug Synergism; Microbial Sensitivity Tests; Penicillanic Acid; Sulbactam | 1986 |
The role of beta-lactamase in staphylococcal resistance to penicillinase-resistant penicillins and cephalosporins.
Topics: beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Cephalothin; Clavulanic Acid; Clavulanic Acids; Methicillin; Microbial Sensitivity Tests; Oxacillin; Penicillanic Acid; Penicillin Resistance; Penicillinase; Penicillins; Staphylococcus aureus; Sulbactam | 1986 |
Comparative activities of the beta-lactamase inhibitors YTR 830, clavulanate, and sulbactam combined with ampicillin and broad-spectrum penicillins against defined beta-lactamase-producing aerobic gram-negative bacilli.
Topics: Ampicillin; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Drug Synergism; Gram-Negative Aerobic Bacteria; Penicillanic Acid; Penicillins; Plasmids; Sulbactam; Tazobactam | 1986 |
Detection, distribution and inhibition of Branhamella catarrhalis beta-lactamases.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Clavulanic Acids; Drug Synergism; Isoelectric Focusing; Microbial Sensitivity Tests; Neisseriaceae; Penicillanic Acid; Sulbactam | 1986 |
Comparative activities of the beta-lactamase inhibitors YTR 830, clavulanate and sulbactam combined with extended-spectrum penicillins against ticarcillin-resistant Enterobacteriaceae and pseudomonads.
Topics: Ampicillin; Clavulanic Acid; Clavulanic Acids; Drug Synergism; Enterobacteriaceae; Mezlocillin; Naphthyridines; Penicillanic Acid; Penicillins; Piperacillin; Pseudomonas; Sulbactam; Ticarcillin | 1986 |
Synergy of amoxycillin combined with clavulanate and YTR 830 in experimental infections in mice.
Topics: Amoxicillin; Animals; Bacterial Infections; Citrobacter; Clavulanic Acid; Clavulanic Acids; Drug Therapy, Combination; Enterobacteriaceae Infections; Female; Mice; Penicillanic Acid; Proteus Infections; Staphylococcal Infections; Tazobactam | 1986 |
Comparative activity of beta-lactamase inhibitors YTR 830, clavulanate, and sulbactam combined with beta-lactams against beta-lactamase-producing anaerobes.
Topics: Anti-Bacterial Agents; Bacteria, Anaerobic; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Microbial Sensitivity Tests; Penicillanic Acid; Sulbactam; Tazobactam | 1986 |
Comparison of four beta-lactamase inhibitors in combination with ampicillin against Mycobacterium tuberculosis.
Topics: Ampicillin; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Penicillanic Acid; Sulbactam | 1987 |
In vitro activity of ampicillin alone and in combination with different concentrations of 6 beta-bromopenicillanic acid, clavulanic acid and mecillinam.
Topics: Amdinocillin; Ampicillin; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Drug Interactions; Drug Synergism; Enterobacteriaceae; Microbial Sensitivity Tests; Penicillanic Acid | 1987 |
Activity of cefazolin and two beta-lactamase inhibitors, clavulanic acid and sulbactam, against Bacteroides fragilis.
Topics: Bacteroides fragilis; beta-Lactamase Inhibitors; Cefazolin; Clavulanic Acid; Clavulanic Acids; Drug Synergism; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Sulbactam | 1987 |
[Sulbactam and clavulanic acid: studies of enzyme kinetics and synergism with ampicillin and mezlocillin].
Topics: Ampicillin; Bacteria; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Drug Synergism; Humans; Kinetics; Mezlocillin; Microbial Sensitivity Tests; Penicillanic Acid; Sulbactam | 1987 |
Synthesis and beta-lactamase inhibitory properties of 2 beta-[(1,2,3-triazol-1-yl)methyl]-2 alpha-methylpenam-3 alpha-carboxylic acid 1,1-dioxide and related triazolyl derivatives.
Topics: Ampicillin; Bacteria; beta-Lactamase Inhibitors; Chemical Phenomena; Chemistry; Clavulanic Acid; Clavulanic Acids; Escherichia coli; Penicillanic Acid; Sulbactam; Tazobactam; Triazoles | 1987 |
Interaction of clavulanic acid, sulbactam and cephamycin antibiotics with beta-lactamases.
Topics: Anti-Bacterial Agents; Bacteria; beta-Lactamase Inhibitors; beta-Lactamases; Cephamycins; Clavulanic Acid; Clavulanic Acids; Drug Interactions; Microbial Sensitivity Tests; Penicillanic Acid; Sulbactam | 1987 |
Activity of beta-lactamase inhibitors in combination with new beta-lactam antibiotics against resistant gram-negative organisms.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Drug Resistance, Microbial; Enterobacter; Gram-Negative Bacteria; Humans; Klebsiella; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas; Sulbactam | 1984 |
Comparative activities of the beta-lactamase inhibitors YTR 830, sodium clavulanate, and sulbactam combined with amoxicillin or ampicillin.
Topics: Amoxicillin; Ampicillin; Bacteria; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Penicillanic Acid; Sulbactam; Tazobactam | 1984 |
Penicillanic acid sulfone: nature of irreversible inactivation of RTEM beta-lactamase from Escherichia coli.
Topics: beta-Lactamase Inhibitors; beta-Lactamases; Chemical Phenomena; Chemistry; Clavulanic Acid; Clavulanic Acids; Drug Stability; Escherichia coli; Isoelectric Focusing; Penicillanic Acid; Spectrophotometry; Sulbactam; Tritium | 1984 |
6-(Methoxymethylene)penicillanic acid: inactivator of RTEM beta-lactamase from Escherichia coli.
Topics: beta-Lactamase Inhibitors; beta-Lactamases; Binding, Competitive; Chemical Phenomena; Chemistry; Clavulanic Acid; Clavulanic Acids; Escherichia coli; Hydrolysis; Isomerism; Kinetics; Penicillanic Acid; Penicillin G; Spectrophotometry, Ultraviolet; Sulbactam | 1984 |
Effects of azlocillin in combination with clavulanic acid, sulbactam, and N-formimidoyl thienamycin against beta-lactamase-producing, carbenicillin-resistant Pseudomonas aeruginosa.
Topics: Azlocillin; beta-Lactamase Inhibitors; beta-Lactamases; Carbenicillin; Clavulanic Acid; Clavulanic Acids; Drug Interactions; Imipenem; Penicillanic Acid; Penicillin Resistance; Pseudomonas aeruginosa; Species Specificity; Sulbactam; Thienamycins | 1982 |
Beta-lactamase inactivation by mechanism-based reagents.
Topics: Anti-Bacterial Agents; Bacteria; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Clavulanic Acid; Lactams; Penicillanic Acid; Sulbactam | 1980 |
Clavulanic acid and CP-45,899: a comparison of their in vitro activity in combination with penicillins.
Topics: Bacteria; Bacteroides fragilis; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Clavulanic Acid; Enterobacteriaceae; Haemophilus influenzae; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Penicillanic Acid; Penicillins; Pseudomonas aeruginosa; Staphylococcus aureus; Sulbactam | 1980 |
Synergistic activity of piperacillin in combination with beta-lactamase inhibitors.
Topics: Anti-Bacterial Agents; Bacteria; beta-Lactamase Inhibitors; beta-Lactams; Clavulanic Acid; Drug Synergism; Penicillanic Acid; Penicillins; Piperacillin; Sulbactam | 1980 |
6-beta-bromo- and 6-beta-iodo penicillanic acid, two novel beta-lactamase inhibitors.
Topics: Ampicillin; Bacteria; beta-Lactamase Inhibitors; beta-Lactams; Clavulanic Acid; Penicillanic Acid | 1981 |
Synergistic activity of cefoperazone in combination with beta-lactamase inhibitors.
Topics: Anti-Bacterial Agents; Bacteria; beta-Lactamase Inhibitors; beta-Lactams; Cefoperazone; Cefotaxime; Cephalosporins; Clavulanic Acid; Drug Synergism; Penicillanic Acid; Sulbactam | 1981 |
Synthesis and beta-lactamase inhibitory properties of 2 beta-(chloromethyl)-2 alpha-methylpenam-3 alpha-carboxylic acid 1,1-dioxide.
Topics: Amoxicillin; Animals; beta-Lactamase Inhibitors; beta-Lactams; Chemical Phenomena; Chemistry; Clavulanic Acid; Escherichia coli Infections; Mice; Mice, Inbred ICR; Penicillanic Acid; Staphylococcal Infections; Staphylococcus aureus | 1981 |
Interaction between non-classical beta-lactam compounds and the Zn2+-containing G and serine R61 and R39 D-alanyl-D-alanine peptidases.
Topics: Actinomycetaceae; Amdinocillin; beta-Lactams; Carboxypeptidases; Cefoxitin; Cephalosporins; Clavulanic Acid; Drug Interactions; Endopeptidases; Enzyme Inhibitors; Imipenem; Kinetics; Penicillanic Acid; Penicillins; Quinoxalines; Serine-Type D-Ala-D-Ala Carboxypeptidase; Streptomyces; Zinc | 1981 |
The effect of inhibitors of beta-lactamases on beta-lactamase extracts and on intact cells.
Topics: Ampicillin; Bacteria; beta-Lactamase Inhibitors; beta-Lactams; Cephaloridine; Clavulanic Acid; Hydrolysis; Microbial Sensitivity Tests; Penicillanic Acid; Sulbactam | 1982 |
Bacteriological investigations with beta-lactamase inhibitors.
Topics: Amoxicillin; Bacteria; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Drug Synergism; Enterobacteriaceae; Penicillanic Acid; Penicillin G; Penicillins; Piperacillin; Pseudomonas aeruginosa | 1982 |
[Biological effects of coordination compounds of transitional metals. The beta-lactamase inhibitory effect of cis-platin, 2-aminopyridine palladium chloride, clavulanic acid and penicillanic acid sulfonate CP 45,899 in the nitrocefin test and Titertek/mic
Topics: Antineoplastic Agents; Bacillus cereus; beta-Lactamase Inhibitors; Cisplatin; Clavulanic Acid; Clavulanic Acids; Dose-Response Relationship, Drug; Organometallic Compounds; Palladium; Penicillanic Acid; Picolines; Sulbactam | 1983 |
[Antibiotic activity and synergism of ceftazidime and netilmicin against gram-negative pathogenic bacteria].
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; Cefsulodin; Ceftazidime; Cephalosporins; Clavulanic Acid; Clavulanic Acids; Drug Resistance, Microbial; Drug Synergism; Enterobacteriaceae; Gentamicins; Gram-Negative Bacteria; Netilmicin; Penicillanic Acid; Sulbactam | 1983 |
[Cefoperazone, cefsulodin and ceftazidime--3 cephalosporins active against Pseudomonas in comparison with their monobactam analogs].
Topics: beta-Lactamase Inhibitors; Cefoperazone; Cefsulodin; Ceftazidime; Cephalosporins; Chemical Phenomena; Chemistry; Clavulanic Acid; Clavulanic Acids; Drug Resistance, Microbial; Humans; Monobactams; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Sulbactam | 1983 |
Effect of pH on activities of novel beta-lactamases and beta-lactamase inhibitors against these beta-lactamases.
Topics: Anti-Bacterial Agents; Bacteria; beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Clavulanic Acids; Enzyme Inhibitors; Hydrogen-Ion Concentration; Kinetics; Penicillanic Acid; Sulbactam; Tazobactam | 1995 |
[Bactericidal activity of combinations of ticarcillin-clavulanic acid or other beta-lactams (amoxicillin, piperacillin-tazobactam, ticarcillin) with gentamicin against Enterococcus faecalis and E. faecium].
Topics: Amoxicillin; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Drug Therapy, Combination; Enterococcus faecalis; Enterococcus faecium; Enzyme Inhibitors; Gentamicins; Humans; In Vitro Techniques; Penicillanic Acid; Penicillin Resistance; Piperacillin; Tazobactam; Ticarcillin | 1995 |
In vitro activity of beta-lactamase inhibitors against clinical isolates of Acinetobacter species.
Topics: Acinetobacter; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamase Inhibitors; Cefotaxime; Ceftazidime; Ceftriaxone; Clavulanic Acid; Clavulanic Acids; Colony Count, Microbial; Imipenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Sensitivity and Specificity; Sulbactam; Tazobactam | 1995 |
Influence of beta-lactamase inhibitors on the activity of oxacillin against methicillin-resistant Staphylococcus aureus.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Clavulanic Acids; Drug Interactions; Methicillin Resistance; Microbial Sensitivity Tests; Oxacillin; Penicillanic Acid; Staphylococcus aureus; Sulbactam; Tazobactam | 1995 |
A piperacillin-tazobactam resistant Escherichia coli strain isolated from a faecal sample of a healthy volunteer.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Clavulanic Acids; Enzyme Inhibitors; Escherichia coli; Feces; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Penicillin Resistance; Piperacillin; Plasmids; Population Surveillance; Tazobactam | 1995 |
beta-Lactamase activity in mycobacteria including Mycobacterium avium and suppression of their growth by a beta-lactamase-stable antibiotic.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Cefepime; Cell Division; Cephalosporins; Clavulanic Acid; Clavulanic Acids; Drug Resistance, Microbial; Isoniazid; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium avium; Penicillanic Acid; Streptomycin; Sulbactam; Tazobactam | 1995 |
Synthesis of new sulfonylamido-penicillanic acid sulfones inhibitors of beta-lactamases.
Topics: beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Hydrogen-Ion Concentration; Kinetics; Molecular Structure; Penicillanic Acid; Sulbactam; Sulfonamides; Sulfones | 1994 |
Comparative activities of clavulanic acid, sulbactam, and tazobactam against clinically important beta-lactamases.
Topics: Bacteria; beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Clavulanic Acids; Penicillanic Acid; Plasmids; Sulbactam; Tazobactam | 1994 |
Cross-resistance to beta-lactam-beta-lactamase inhibitor combinations and clindamycin among cefoxitin-resistant and cefoxitin-susceptible strains of the Bacteroides fragilis group.
Topics: Anti-Bacterial Agents; Bacteroides; Bacteroides fragilis; Bacteroides Infections; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Clindamycin; Drug Resistance, Microbial; Drug Synergism; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Tazobactam | 1993 |
[Bacteremia by Escherichia coli resistant to amoxycillin/clavulanic acid, ampicillin/sulbactam and piperacillin/tazobactam].
Topics: Aged; Ampicillin; Clavulanic Acid; Clavulanic Acids; Drug Resistance, Microbial; Drug Therapy, Combination; Escherichia coli; Escherichia coli Infections; Female; Humans; Penicillanic Acid; Sulbactam; Tazobactam | 1994 |
Antibacterial activity of clavulanate and tazobactam on Peptostreptococcus spp.
Topics: Amoxicillin; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Peptostreptococcus; Piperacillin; Tazobactam | 1994 |
In vitro extracellular and intracellular activities of clavulanic acid and those of piperacillin and ceftriaxone alone and in combination with tazobactam against clinical isolates of Legionella species.
Topics: Animals; Ceftriaxone; Cells, Cultured; Clavulanic Acid; Clavulanic Acids; Drug Interactions; Drug Therapy, Combination; Extracellular Space; Guinea Pigs; Intracellular Fluid; Legionella; Legionella pneumophila; Legionnaires' Disease; Macrophages, Alveolar; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Tazobactam | 1994 |
Ex vivo pharmacodynamic study of piperacillin alone and in combination with tazobactam, compared with ticarcillin plus clavulanic acid.
Topics: Adult; beta-Lactamase Inhibitors; Biological Assay; Chromatography, High Pressure Liquid; Clavulanic Acid; Clavulanic Acids; Drug Synergism; Drug Therapy, Combination; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Serum Bactericidal Test; Tazobactam; Ticarcillin | 1993 |
Characterization of a new TEM-type beta-lactamase resistant to clavulanate, sulbactam, and tazobactam in a clinical isolate of Escherichia coli.
Topics: beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Clavulanic Acids; Cloning, Molecular; Drug Resistance, Microbial; Escherichia coli; Genes, Bacterial; Humans; Mutation; Penicillanic Acid; Phenotype; Sulbactam; Tazobactam | 1993 |
In-vitro evaluation of the four beta-lactamase inhibitors: BRL42715, clavulanic acid, sulbactam, and tazobactam.
Topics: Anti-Bacterial Agents; Bacteria; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Clavulanic Acid; Clavulanic Acids; Drug Resistance, Microbial; Escherichia coli; Lactams; Microbial Sensitivity Tests; Penicillanic Acid; Sulbactam; Tazobactam | 1993 |
Effect of five irreversible inhibitors on beta-lactamase from Shigella flexneri UCSF-129.
Topics: Ampicillin; Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Clavulanic Acid; Clavulanic Acids; Drug Synergism; Lactams; Microbial Sensitivity Tests; Penicillanic Acid; Shigella flexneri | 1993 |
Activity of 13 beta-lactam agents combined with BRL 42715 against beta-lactamase producing gram-negative bacteria compared to combinations with clavulanic acid, tazobactam and sulbactam.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Clavulanic Acid; Clavulanic Acids; Drug Therapy, Combination; Enzyme Inhibitors; Gram-Negative Bacteria; Lactams; Penicillanic Acid; Sulbactam; Tazobactam | 1993 |
Kinetic interactions of tazobactam with beta-lactamases from all major structural classes.
Topics: Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Clavulanic Acid; Clavulanic Acids; Hydrolysis; Isoelectric Focusing; Kinetics; Molecular Weight; Penicillanic Acid; Spectrophotometry, Ultraviolet; Tazobactam | 1993 |
Relative efficacy of tazobactam, sulbactam and clavulanic acid in enhancing the potency of ampicillin against clinical isolates of Enterobacteriaceae.
Topics: Ampicillin; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Drug Synergism; Enterobacteriaceae; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Sulbactam; Tazobactam | 1993 |
Susceptibilities of beta-lactamase-positive and -negative strains of Campylobacter coli to beta-lactam agents.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Campylobacter coli; Clavulanic Acid; Clavulanic Acids; Microbial Sensitivity Tests; Penicillanic Acid; Sulbactam; Tazobactam | 1993 |
Selection of variants of the TEM-1 beta-lactamase, encoded by a plasmid of clinical origin, with increased resistance to beta-lactamase inhibitors.
Topics: Amoxicillin; beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Clavulanic Acids; Conjugation, Genetic; Drug Resistance, Microbial; Escherichia coli; Isoelectric Focusing; Microbial Sensitivity Tests; Mutation; Penicillanic Acid; Plasmids; Restriction Mapping; Sulbactam; Tazobactam | 1993 |
In vitro activity of cefodizime (HR-221) in combination with beta-lactamase inhibitors.
Topics: Anti-Bacterial Agents; Bacteria; beta-Lactamase Inhibitors; Cefotaxime; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Drug Interactions; Drug Stability; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Tazobactam | 1993 |
A kinetic study of NMC-A beta-lactamase, an Ambler class A carbapenemase also hydrolyzing cephamycins.
Topics: Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Binding Sites; Cephamycins; Clavulanic Acid; Clavulanic Acids; Enterobacter cloacae; Enzyme Inhibitors; Escherichia coli; Hydrolysis; Kinetics; Molecular Structure; Penicillanic Acid; Recombinant Proteins; Substrate Specificity; Sulbactam; Tazobactam | 1996 |
Inhibition of TEM-2 beta-lactamase from Escherichia coli by clavulanic acid: observation of intermediates by electrospray ionization mass spectrometry.
Topics: beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Clavulanic Acids; Dithiothreitol; Enzyme Inhibitors; Escherichia coli; Kinetics; Mass Spectrometry; Models, Chemical; Molecular Structure; Penicillanic Acid; Serine; Serine Endopeptidases; Trypsin | 1996 |
Assessment of two penicillins plus beta-lactamase inhibitors versus cefotaxime in treatment of murine Klebsiella pneumoniae infections.
Topics: Animals; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Cefotaxime; Cephalosporins; Clavulanic Acid; Clavulanic Acids; Colony Count, Microbial; Drug Combinations; Drug Therapy, Combination; Female; Klebsiella Infections; Klebsiella pneumoniae; Lung; Mice; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Piperacillin; Pneumonia, Bacterial; Tazobactam; Ticarcillin | 1996 |
Antimicrobial susceptibilities of Campylobacter jejuni and Campylobacter coli to 12 beta-lactam agents and combinations with beta-lactamase inhibitors.
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; Campylobacter coli; Campylobacter jejuni; Cephalosporins; Clavulanic Acid; Clavulanic Acids; Enzyme Inhibitors; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Sulbactam; Tazobactam | 1996 |
Fixed or variable concentrations of beta-lactamase inhibitors in in-vitro tests?
Topics: beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Enzyme Inhibitors; Microbial Sensitivity Tests; Penicillanic Acid; Sulbactam; Tazobactam | 1996 |
Antibiotic resistance and production of extended-spectrum beta-lactamases amongst Klebsiella spp. from intensive care units in Europe.
Topics: Ampicillin; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; Carbapenems; Ceftazidime; Cephalosporins; Clavulanic Acid; Clavulanic Acids; Drug Therapy, Combination; Enzyme Inhibitors; Europe; Humans; Intensive Care Units; Klebsiella; Klebsiella Infections; Microbial Sensitivity Tests; Monobactams; Penicillanic Acid; Piperacillin; Tazobactam | 1996 |
Timed killing kinetic studies of the interaction between ciprofloxacin and beta-lactams against gram-negative bacilli.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aztreonam; Ceftazidime; Cephalosporins; Ciprofloxacin; Clavulanic Acid; Clavulanic Acids; Drug Interactions; Drug Therapy, Combination; Enterobacter cloacae; Enzyme Inhibitors; Kinetics; Klebsiella pneumoniae; Microbial Sensitivity Tests; Monobactams; Penicillanic Acid; Penicillins; Piperacillin; Pseudomonas aeruginosa; Serratia marcescens; Tazobactam; Ticarcillin; Time Factors | 1996 |
Tazobactam is a potent inactivator of selected inhibitor-resistant class A beta-lactamases.
Topics: Ampicillin; Ampicillin Resistance; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Clavulanic Acid; Enzyme Inhibitors; Escherichia coli; Kinetics; Penicillanic Acid; Penicillins; Piperacillin; Tazobactam | 1997 |
Tazobactam-piperacillin compared with sulbactam-ampicillin, clavulanic acid-ticarcillin, sulbactam-cefoperazone, and piperacillin for activity against beta-lactamase-producing bacteria isolated from patients with complicated urinary tract infections.
Topics: Ampicillin; beta-Lactamase Inhibitors; Cefoperazone; Cephalosporins; Clavulanic Acid; Clavulanic Acids; Colony Count, Microbial; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Inhibitors; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Piperacillin; Retrospective Studies; Sulbactam; Tazobactam; Ticarcillin; Urinary Tract; Urinary Tract Infections | 1997 |
Characterization of a beta-lactamase from Mycobacterium smegmatis SN2.
Topics: Amino Acid Sequence; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Enzyme Inhibitors; Molecular Sequence Data; Mycobacterium; Penicillanic Acid; Sequence Alignment; Substrate Specificity; Sulbactam | 1997 |
Comparative in vitro evaluation of piperacillin/tazobactam in a tertiary care hospital.
Topics: Amoxicillin; Ceftazidime; Cephalosporin Resistance; Cephalosporins; Ciprofloxacin; Clavulanic Acid; Enzyme Inhibitors; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Intensive Care Units; Microbial Sensitivity Tests; Penicillanic Acid; Penicillin Resistance; Penicillins; Piperacillin; Tazobactam | 1997 |
Clinical inhibitor-resistant mutants of the beta-lactamase TEM-1 at amino-acid position 69. Kinetic analysis and molecular modelling.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Drug Resistance, Microbial; Escherichia coli; Kinetics; Models, Molecular; Molecular Conformation; Penicillanic Acid; Protein Conformation; Sulbactam; Tazobactam | 1998 |
Comparative in-vitro activities of GD-40 and other beta-lactamase inhibitors against TEM-1 and SHV-2 beta-lactamases.
Topics: beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Enzyme Inhibitors; Penicillanic Acid; Sulbactam; Tazobactam | 1998 |
Ceftazidime and aztreonam resistance in Providencia stuartii: characterization of a natural TEM-derived extended-spectrum beta-lactamase, TEM-60.
Topics: Anti-Bacterial Agents; Aztreonam; beta-Lactamase Inhibitors; beta-Lactamases; Ceftazidime; Cephalosporins; Clavulanic Acid; Drug Interactions; Drug Resistance, Multiple; Enzyme Inhibitors; Isoelectric Focusing; Microbial Sensitivity Tests; Molecular Sequence Data; Monobactams; Penicillanic Acid; Providencia; Sulbactam; Tazobactam | 1998 |
Kinetic analysis of an inhibitor-resistant variant of the OHIO-1 beta-lactamase, an SHV-family class A enzyme.
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Circular Dichroism; Clavulanic Acid; Enzyme Inhibitors; Escherichia coli; Isoleucine; Kinetics; Methionine; Microbial Sensitivity Tests; Penicillanic Acid; Point Mutation; Protein Conformation; Sulbactam; Tazobactam | 1998 |
[Beta-lactamase producers and other bacteria: which ones to take into consideration and when? The concept of beta-lactamase inhibitor].
Topics: Anti-Bacterial Agents; Bacteria; Bacteroides fragilis; beta-Lactamase Inhibitors; Clavulanic Acid; Haemophilus influenzae; Humans; Klebsiella; Klebsiella pneumoniae; Moraxella catarrhalis; Penicillanic Acid; Proteus vulgaris; Staphylococcus aureus; Streptococcus pneumoniae; Sulbactam; Tazobactam | 1998 |
Comparative activities of novel beta-lactamase inhibitors, 6-exomethylene penamsulfones (CH1240, CH2140) in experimental mouse infection model.
Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; beta-Lactamase Inhibitors; Citrobacter; Clavulanic Acid; Enterobacteriaceae Infections; Enzyme Inhibitors; Escherichia coli Infections; Lethal Dose 50; Male; Mice; Mice, Inbred ICR; Penicillanic Acid; Pseudomonas Infections; Sulbactam; Triazoles | 1998 |
Interaction between class B beta-lactamases and suicide substrates of active-site serine beta-lactamases.
Topics: beta-Lactamases; Binding Sites; Catalysis; Clavulanic Acid; Isomerism; Penicillanic Acid; Substrate Specificity; Sulbactam; Tazobactam | 1999 |
Clavulanate induces expression of the Pseudomonas aeruginosa AmpC cephalosporinase at physiologically relevant concentrations and antagonizes the antibacterial activity of ticarcillin.
Topics: Anti-Bacterial Agents; Cephalosporinase; Clavulanic Acid; Enzyme Induction; Enzyme Inhibitors; Genes, Bacterial; Humans; Penicillanic Acid; Penicillins; Piperacillin; Pseudomonas aeruginosa; Tazobactam; Ticarcillin | 1999 |
Aspartic acid for asparagine substitution at position 276 reduces susceptibility to mechanism-based inhibitors in SHV-1 and SHV-5 beta-lactamases.
Topics: Amino Acid Substitution; Anti-Bacterial Agents; Asparagine; Aspartic Acid; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Clavulanic Acid; Enzyme Inhibitors; Escherichia coli; Inhibitory Concentration 50; Microbial Sensitivity Tests; Penicillanic Acid; Sulbactam; Tazobactam | 1999 |
In-vitro susceptibilities of species of the Bacteroides fragilis group to newer beta-lactam agents.
Topics: Amoxicillin; Ampicillin; Anti-Bacterial Agents; Bacteroides fragilis; beta-Lactamase Inhibitors; Cefoxitin; Ceftizoxime; Chloramphenicol; Clavulanic Acid; Clindamycin; Drug Therapy, Combination; Enzyme Inhibitors; Imipenem; Metronidazole; Mezlocillin; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Piperacillin; Species Specificity; Sulbactam; Tazobactam; Thienamycins; Ticarcillin | 1999 |
Penetration of beta-lactamase inhibitors into the periplasm of gram-negative bacteria.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactams; Cell Membrane Permeability; Clavulanic Acid; Enterobacter cloacae; Enzyme Inhibitors; Escherichia coli; Gram-Negative Bacteria; Klebsiella pneumoniae; Lactams; Penicillanic Acid; Periplasm; Sulbactam; Tazobactam | 1999 |
Evaluation of inhibition of the carbenicillin-hydrolyzing beta-lactamase PSE-4 by the clinically used mechanism-based inhibitors.
Topics: Acylation; beta-Lactamase Inhibitors; beta-Lactamases; Binding Sites; Carbenicillin; Clavulanic Acid; Computer Simulation; Enzyme Inhibitors; Escherichia coli; Hydrogen Bonding; Kinetics; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Penicillanic Acid; Penicillin Resistance; Penicillinase; Pseudomonas aeruginosa; Sulbactam; Tazobactam; Thermodynamics | 2000 |
Comparative evaluation of the in vitro activity of three combinations of beta-lactams with beta-lactamase inhibitors: piperacillin/tazobactam, ticarcillin/clavulanic acid and ampicillin/sulbactam.
Topics: Ampicillin; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamase Inhibitors; Clavulanic Acid; Cross Infection; Drug Therapy, Combination; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Sulbactam; Tazobactam; Ticarcillin | 2000 |
Structure-function analysis of alpha-helix H4 using PSE-4 as a model enzyme representative of class A beta-lactamases.
Topics: beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; Circular Dichroism; Clavulanic Acid; Computer Simulation; Enzyme Inhibitors; Kinetics; Microbial Sensitivity Tests; Models, Molecular; Mutagenesis, Site-Directed; Penicillanic Acid; Protein Structure, Secondary; Recombinant Proteins; Structure-Activity Relationship; Sulbactam; Tazobactam | 2000 |
In vitro susceptibilities of Capnocytophaga isolates to beta-lactam antibiotics and beta-lactamase inhibitors.
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamase Inhibitors; Capnocytophaga; Clavulanic Acid; Gram-Negative Bacterial Infections; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Tazobactam | 2000 |
Properties of multidrug-resistant, ESBL-producing Proteus mirabilis isolates and possible role of beta-lactam/beta-lactamase inhibitor combinations.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Clavulanic Acid; Drug Resistance, Microbial; Drug Resistance, Multiple; Enzyme Inhibitors; Genes, Bacterial; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Proteus Infections; Proteus mirabilis; Tazobactam | 2001 |
[Occurrence of beta-lactamase type ESBL and IBL in Pseudomonas aeruginosa rods].
Topics: Animals; beta-Lactamases; Cattle; Cefoxitin; Clavulanic Acid; Dogs; Fishes; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Species Specificity; Swine; Tazobactam | 2001 |
Factors governing intrinsic chemical reactivity differences between clavulanic and penicillanic acids.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Enzyme Inhibitors; Penicillanic Acid; Solutions; Structure-Activity Relationship; Thermodynamics | 2002 |
Understanding resistance to beta-lactams and beta-lactamase inhibitors in the SHV beta-lactamase: lessons from the mutagenesis of SER-130.
Topics: Ampicillin; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Binding, Competitive; Clavulanic Acid; Drug Resistance, Microbial; Enzyme Inhibitors; Escherichia coli; Kinetics; Models, Chemical; Mutagenesis; Mutagenesis, Site-Directed; Penicillanic Acid; Plasmids; Serine; Tazobactam; Thermodynamics; Time Factors | 2003 |
[Phenotypes of beta-lactam resistance in the genus Aeromonas].
Topics: Aeromonas; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Clavulanic Acid; Enzyme Inhibitors; Isoelectric Focusing; Isoelectric Point; Lactams; Microbial Sensitivity Tests; Penicillanic Acid; Phenotype; Tazobactam | 2003 |
Following the reactions of mechanism-based inhibitors with beta-lactamase by Raman crystallography.
Topics: Amines; Amino Acid Substitution; beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Crystallization; Deuterium Oxide; Enzyme Inhibitors; Kinetics; Microscopy; Models, Molecular; Penicillanic Acid; Recombinant Proteins; Spectrum Analysis, Raman; Sulbactam; Tazobactam; Water | 2003 |
Evaluation of penicillin-based inhibitors of the class A and B beta-lactamases from Bacillus anthracis.
Topics: Anti-Bacterial Agents; Bacillus anthracis; beta-Lactamases; Chelating Agents; Clavulanic Acid; Enzyme Inhibitors; Hydrolysis; Inhibitory Concentration 50; Iron; Kinetics; Models, Chemical; Penicillanic Acid; Penicillins; Spectrophotometry; Tazobactam | 2004 |
In vitro activities of the beta-lactamase inhibitors clavulanic acid, sulbactam, and tazobactam alone or in combination with beta-lactams against epidemiologically characterized multidrug-resistant Acinetobacter baumannii strains.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactams; Clavulanic Acid; DNA; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Electrophoresis, Gel, Pulsed-Field; Enzyme Inhibitors; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Sulbactam; Tazobactam | 2004 |
In vitro activity of AVE1330A, an innovative broad-spectrum non-beta-lactam beta-lactamase inhibitor.
Topics: Azepines; Bacteria; beta-Lactamases; Ceftazidime; Cephalosporins; Clavulanic Acid; Dealkylation; Enzyme Inhibitors; Escherichia coli; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Piperacillin; Staphylococcus aureus; Sulfuric Acid Esters; Tazobactam | 2004 |
[Treatment mostly not in line with current knowledge. New guidelines for sinusitis therapy].
Topics: Acute Disease; Bacterial Infections; Ceftibuten; Cephalosporins; Chronic Disease; Clavulanic Acid; Drug Resistance, Multiple; Humans; Mometasone Furoate; Penicillanic Acid; Pregnadienediols; Sinusitis; Treatment Outcome | 2004 |
Antibacterial susceptibility of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae and Escherichia coli.
Topics: Adult; Amikacin; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; beta-Lactamases; Child; Ciprofloxacin; Clavulanic Acid; Drug Resistance, Bacterial; Enzyme Inhibitors; Escherichia coli; Humans; In Vitro Techniques; Israel; Klebsiella pneumoniae; Microbial Sensitivity Tests; Odds Ratio; Penicillanic Acid; Piperacillin; Prevalence; Tazobactam | 2005 |
High resolution crystal structures of the trans-enamine intermediates formed by sulbactam and clavulanic acid and E166A SHV-1 {beta}-lactamase.
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Binding Sites; Clavulanic Acid; Crystallography, X-Ray; Drug Resistance, Bacterial; Enzyme Inhibitors; Klebsiella pneumoniae; Models, Chemical; Models, Molecular; Mutation; Penicillanic Acid; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Serine; Spectrum Analysis, Raman; Sulbactam; Tazobactam; Time Factors; X-Rays | 2005 |
Comparative activities of the beta-lactamase inhibitors YTR 830, clavulanic acid and sulbactam combined with ampicillin and piperacillin against beta-lactamase producing anaerobic bacteria.
Topics: Ampicillin; Anti-Bacterial Agents; Bacteroides fragilis; beta-Lactamase Inhibitors; Clavulanic Acid; Enzyme Inhibitors; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Sulbactam; Tazobactam | 1989 |
Susceptibilities of ESBL-producing Enterobacteriaceae to ertapenem, meropenem and piperacillin-tazobactam with and without clavulanic acid.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Clavulanic Acid; Drug Interactions; Ertapenem; Escherichia coli; Klebsiella pneumoniae; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Thienamycins | 2007 |
Raman crystallographic studies of the intermediates formed by Ser130Gly SHV, a beta-lactamase that confers resistance to clinical inhibitors.
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Clavulanic Acid; Crystallography, X-Ray; Enzyme Inhibitors; Glycine; Penicillanic Acid; Serine; Spectrum Analysis, Raman; Stereoisomerism; Tazobactam | 2007 |
Sulbactam forms only minimal amounts of irreversible acrylate-enzyme with SHV-1 beta-lactamase.
Topics: Acrylates; Amino Acid Substitution; beta-Lactamases; Catalytic Domain; Clavulanic Acid; Crystallization; Enzyme Inhibitors; Imines; Kinetics; Molecular Structure; Penicillanic Acid; Recombinant Proteins; Serine; Spectrum Analysis, Raman; Sulbactam; Tazobactam | 2007 |
Biochemical Characterization of SFC-1, a class A carbapenem-hydrolyzing beta-lactamase.
Topics: Aztreonam; beta-Lactamases; Carbapenems; Catalysis; Cephalosporins; Clavulanic Acid; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Hydrolysis; Kinetics; Molecular Weight; Penicillanic Acid; Penicillins; Recombinant Proteins; Serratia; Sulbactam; Tazobactam | 2007 |
Sensitivity pattern of gram negative bacilli to three beta-lactam/beta-lactamase inhibitor combinations using the automated API system.
Topics: Acinetobacter; Amoxicillin; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactams; Clavulanic Acid; Enterobacteriaceae; Enzyme Inhibitors; Gram-Negative Bacteria; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Pseudomonas; Stenotrophomonas; Tazobactam; Ticarcillin | 2007 |
Different intermediate populations formed by tazobactam, sulbactam, and clavulanate reacting with SHV-1 beta-lactamases: Raman crystallographic evidence.
Topics: beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Crystallography, X-Ray; Enzyme Inhibitors; Imines; Penicillanic Acid; Quantum Theory; Spectrum Analysis, Raman; Sulbactam; Tazobactam | 2009 |
Pylephlebitis after a duodenal ulcer in a patient with metastasised colon carcinoma treated with chemotherapy and bevacizumab: a case report.
Topics: Aged; Amoxicillin; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bacterial Infections; Bevacizumab; Clavulanic Acid; Colorectal Neoplasms; Duodenal Ulcer; Humans; Male; Penicillanic Acid; Piperacillin; Portal Vein; Tazobactam; Thrombophlebitis | 2009 |
Detection of the novel extended-spectrum beta-lactamase OXA-161 from a plasmid-located integron in Pseudomonas aeruginosa clinical isolates from Spain.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Clavulanic Acid; Gentamicins; Humans; Imipenem; Integrons; Meropenem; Molecular Sequence Data; Penicillanic Acid; Piperacillin; Plasmids; Pseudomonas aeruginosa; Pseudomonas Infections; Spain; Tazobactam; Thienamycins | 2009 |
Inhibitor resistance in the KPC-2 beta-lactamase, a preeminent property of this class A beta-lactamase.
Topics: Anti-Bacterial Agents; beta-Lactamases; Catalytic Domain; Clavulanic Acid; Computer Simulation; Enzyme Inhibitors; Kinetics; Microbial Sensitivity Tests; Penicillanic Acid; Spectrometry, Mass, Electrospray Ionization; Sulbactam; Tazobactam | 2010 |
Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase.
Topics: Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Cephalosporinase; Clavulanic Acid; Computer Simulation; Enzyme Inhibitors; Hydrogen Bonding; Kinetics; Microbial Sensitivity Tests; Molecular Structure; Mutagenesis, Site-Directed; Penicillanic Acid; Protein Structure, Secondary; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity; Sulbactam; Tazobactam | 2010 |
Carbapenem-hydrolyzing GES-type extended-spectrum beta-lactamase in Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Clavulanic Acid; Escherichia coli; Microbial Sensitivity Tests; Models, Genetic; Molecular Sequence Data; Penicillanic Acid; Polymerase Chain Reaction; Tazobactam | 2011 |
Novel insights into the mode of inhibition of class A SHV-1 beta-lactamases revealed by boronic acid transition state inhibitors.
Topics: beta-Lactamase Inhibitors; Boronic Acids; Cefoperazone; Ceftazidime; Clavulanic Acid; Enzyme Inhibitors; Klebsiella pneumoniae; Magnetic Resonance Spectroscopy; Penicillanic Acid; Sulbactam; Tazobactam | 2011 |
Exploring the inhibition of CTX-M-9 by beta-lactamase inhibitors and carbapenems.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Carbapenems; Clavulanic Acid; Enzyme Inhibitors; Escherichia coli Proteins; Kinetics; Meropenem; Molecular Dynamics Simulation; Molecular Structure; Penicillanic Acid; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulbactam; Tazobactam; Thienamycins | 2011 |
In vitro selection of variants resistant to beta-lactams plus beta-lactamase inhibitors in CTX-M beta-lactamases: predicting the in vivo scenario?
Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; beta-Lactamases; Cefotaxime; Ceftazidime; Cephalosporin Resistance; Clavulanic Acid; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Evolution, Molecular; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Penicillanic Acid; Piperacillin; Plasmids; Selection, Genetic; Tazobactam | 2011 |
Class A carbapenemase FPH-1 from Francisella philomiragia.
Topics: Bacterial Proteins; beta-Lactamases; beta-Lactams; Carbapenems; Clavulanic Acid; Doripenem; Ertapenem; Escherichia coli; Francisella; Imipenem; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Sulbactam; Tazobactam; Thienamycins | 2012 |
Purification and characterization of OXA-23 from Acinetobacter baumannii.
Topics: Acinetobacter baumannii; beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Dose-Response Relationship, Drug; Enzyme Activation; Escherichia coli; Kinetics; Models, Molecular; Penicillanic Acid; Structure-Activity Relationship; Substrate Specificity; Sulbactam; Surface Properties; Tazobactam | 2013 |
[Inhibitors of the New Delhi-Metallolactamase].
Topics: Bacterial Infections; beta-Lactamase Inhibitors; beta-Lactamases; Cell Membrane; Clavulanic Acid; Drug Resistance, Bacterial; Drug Resistance, Microbial; Enzyme Inhibitors; Klebsiella pneumoniae; Methicillin-Resistant Staphylococcus aureus; Penicillanic Acid; Tazobactam | 2012 |
Following drug uptake and reactions inside Escherichia coli cells by Raman microspectroscopy.
Topics: beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Escherichia coli; Escherichia coli Proteins; Freeze Drying; Penicillanic Acid; Spectrum Analysis, Raman; Tazobactam | 2014 |
Genetic and kinetic characterization of the novel AmpC β-lactamases DHA-6 and DHA-7.
Topics: Ampicillin; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Clavulanic Acid; Enterobacter cloacae; Escherichia coli; Humans; Klebsiella oxytoca; Microbial Sensitivity Tests; Penicillanic Acid; Sulbactam; Tazobactam | 2014 |
Genetic and Biochemical Characterization of FRI-1, a Carbapenem-Hydrolyzing Class A β-Lactamase from Enterobacter cloacae.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Carbapenems; Clavulanic Acid; Cloning, Molecular; Drug Resistance, Multiple, Bacterial; Enterobacter cloacae; Humans; Inhibitory Concentration 50; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillanic Acid; Plasmids; Sequence Homology, Amino Acid; Tazobactam | 2015 |
Two cases of spondylodiscitis caused by Parvimonas micra.
Topics: Aged; Anti-Bacterial Agents; beta-Lactamase Inhibitors; C-Reactive Protein; Clavulanic Acid; Clindamycin; Discitis; Female; Gram-Positive Bacterial Infections; Humans; Magnetic Resonance Imaging; Male; Penicillanic Acid; Peptostreptococcus; Tazobactam | 2015 |
Characterization of VCC-1, a Novel Ambler Class A Carbapenemase from Vibrio cholerae Isolated from Imported Retail Shrimp Sold in Canada.
Topics: Amino Acid Sequence; Animals; Aztreonam; Bacterial Proteins; Base Sequence; beta-Lactamases; Canada; Carbapenems; Cephalosporins; Clavulanic Acid; Drug Resistance, Multiple, Bacterial; Genome, Bacterial; Humans; Microbial Sensitivity Tests; Penaeidae; Penicillanic Acid; Penicillins; Seafood; Sequence Alignment; Sequence Analysis, DNA; Tazobactam; Vibrio cholerae | 2016 |
Susceptibility to cephalosporin combinations and aztreonam/avibactam among third-generation cephalosporin-resistant Enterobacteriaceae recovered on hospital admission.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Azabicyclo Compounds; Aztreonam; beta-Lactamase Inhibitors; Cephalosporin Resistance; Cephalosporins; Clavulanic Acid; Enterobacteriaceae; Enterobacteriaceae Infections; Female; Germany; Hospitals; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Tazobactam; Young Adult | 2017 |
Simultaneous determination of clavulanic acid and tazobactam in bovine milk by HPLC.
Topics: Animals; Anti-Bacterial Agents; Calibration; Cattle; Chromatography, High Pressure Liquid; Clavulanic Acid; Female; Food Contamination; Humans; Lactation; Limit of Detection; Milk; Penicillanic Acid; Tazobactam | 2017 |
Topics: Amoxicillin; Anti-Bacterial Agents; Clavulanic Acid; Clindamycin; Diagnosis, Differential; Female; Humans; Middle Aged; Penicillanic Acid; Penicillin G; Peritonitis; Piperacillin; Streptococcal Infections; Streptococcus pyogenes; Tazobactam; Treatment Outcome | 2018 |
[The control of the critical quality attributes of amoxicillin and clavulanate potassium tablet].
Topics: Amoxicillin; Clavulanic Acid; Drug Contamination; Penicillanic Acid; Tablets | 2016 |