Compounds > clavulanic acid
Page last updated: 2024-08-23

clavulanic acid and meropenem

clavulanic acid has been researched along with meropenem in 64 studies

Research

Studies (64)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's15 (23.44)29.6817
2010's40 (62.50)24.3611
2020's9 (14.06)2.80

Authors

AuthorsStudies
Cattoir, V; Corvec, S; Drugeon, H; Faccone, D; Galas, M; Mugnier, P; Nordmann, P; Pasteran, F; Petroni, A; Poirel, L; Rapoport, M1
Correia, A; Domingues, MR; Domingues, P; Fonseca, F; Henriques, I; Saavedra, MJ; Samyn, B; Sarmento, AC; van Beeumen, J1
Bonnet, R; Neuwirth, C; Robin, F; Siebor, E1
Courvalin, P; Dupêchez, M; Galimand, M; Lambert, T; Meziane-Cherif, D1
Lombardo, F; Obach, RS; Waters, NJ1
Castanheira, M; Samuelsen, Ø; Spencer, J; Walsh, TR1
Arakawa, Y; Ishikawa, K; Nagano, N; Nagano, Y; Wachino, J1
Beceiro, A; Bou, G; Cisneros, JM; Fernández-Cuenca, F; Martínez-Martínez, L; Pachón, J; Pascual, A; Pérez, A; Rodríguez-Baño, J; Vila, J1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Ghori, S; Griggs, DJ; Johnson, MM; Mott, A; Peake, L; Piddock, LJ1
Cho, HS; Giske, CG; Lee, K; Sundman, K; Toleman, MA; Walsh, TR; Yong, D1
Girlich, D; Nordmann, P; Poirel, L1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Kotsakis, SD; Legakis, NJ; Miriagou, V; Papagiannitsis, CC; Tzelepi, E; Tzouvelekis, LS1
Appelbaum, PC; Credito, K; Kosowska-Shick, K1
Bonomo, RA; Distler, AM; Endimiani, A; Hornick, JM; Hujer, AM; Hujer, KM; Papp-Wallace, KM; Taracila, M1
Nordmann, P; Poirel, L; Rodríguez-Martínez, JM; Ronco, E1
Kotsakis, SD; Miriagou, V; Tzelepi, E; Tzouvelekis, LS1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Abendroth, J; Atkins, K; Boyer, SH; Clifton, MC; Dudley, MN; Durso, S; Griffith, DC; Hecker, SJ; Hirst, GC; King, P; Lomovskaya, O; Loutit, JS; Morgan, EE; Potts, KT; Raymond, A; Reddy, KR; Sabet, M; Sun, D; Tarazi, Z; Totrov, M; Tsivkovski, R1
Benvenuti, M; Burns, CJ; Chu, GH; Cusick, SM; Daigle, DM; De Luca, F; Docquier, JD; Hamrick, JC; Jackson, RW; Liu, B; Mangani, S; McGarry, D; Pevear, DC; Pozzi, C; Trout, REL; Weiss, WJ; Xerri, L1
Broide, E; Raveh, D; Rudensky, B; Yinnon, AM1
Barry, CE; Blanchard, JS; Boshoff, HI; Hugonnet, JE; Tremblay, LW1
Holzgrabe, U1
Albertí, S; Juan, C; Mulet, X; Oliver, A; Pérez, JL; Zamorano, L1
Campos-Rivera, MP; Escalante-Fuentes, WG; Ocampo-Candiani, J; Pucci, MJ; Vera-Cabrera, L; Welsh, O1
Dauby, N; Mouchet, F; Muylle, I; Payen, MC; Sergysels, R1
Bethel, CR; Bonnet, R; Bonomo, RA; Distler, AM; Endimiani, A; Hujer, AM; Hujer, KM; Papp-Wallace, K; Shyr, T; Taracila, M; Thomson, JM1
Clumeck, N; De Wit, S; Martin, C; Muylle, I; Payen, MC; Sergysels, R; Van Laethem, Y1
Arora, K; Barry, CE; Boshoff, HI; Dayao, E; England, K; Schimel, D; Via, LE; Weiner, D1
Antunes, NT; Frase, H; Toth, M; Vakulenko, SB; Vakulenko, V1
Arthur, M; Dubée, V; Dubost, L; Ethève-Quelquejeu, M; Gutmann, L; Hugonnet, JE; Mainardi, JL; Marie, A; Triboulet, S1
Conklin, BC; Hutton, RA; Li, M; Skalweit, MJ; Taracila, MA1
Alffenaar, JW; Bolhuis, MS; Centis, R; D'Ambrosio, L; De Lorenzo, S; Migliori, GB; Piana, A; Sotgiu, G; Spanevello, A; Tiberi, S; van Altena, R; Viggiani, P1
Drobniewski, F; Gonzalo, X1
Ahuja, V; Balasubramanian, V; Balganesh, M; Bhattacharjee, D; Dinesh, N; Ganguly, S; Kumar, N; Panduga, V; Parab, M; Ramachandran, V; Reddy, J; Shandil, R; Sharma, S; Solapure, S; Vishwas, KG1
Frase, H; Lamoureaux, TL; Toth, M; Vakulenko, SB; Vakulenko, V1
Arthur, M; Cordillot, M; Dubée, V; Dubost, L; Hugonnet, JE; Mainardi, JL; Marie, A; Triboulet, S1
Bethel, CR; Blanchard, JS; Bonomo, RA; Hazra, S; Hujer, AM; Kurz, SG; Nguyen, L; Smith, KM; Tremblay, LW; Wolff, KA; Xu, Y1
Cielecka-Piontek, J; Garbacki, P; Paczkowska, M; Szymanowska-Powałowska, D; Zalewski, P; Łysakowski, P1
Khosravi, Y; Mariappan, V; Ng, SL; Vadivelu, J; Vellasamy, KM1
Ängeby, K; Bruchfeld, J; Davies Forsman, L; Giske, CG; Juréen, P; Schön, T2
Cufré, M; García, A; González Montaner, P; Palmero, D; Poggi, S; Vescovo, M1
Butler-Laporte, G; Menzies, D; Winters, N1
Lu, J; Pang, Y; Wang, Y; Zhang, D1
Abdo Arbex, M; Akkerman, OW; Alarcon Arrascue, E; Alarcon Guizado, V; Aleska, A; Alffenaar, JW; Avchinko, V; Bonini, EH; Caminero, JA; Centis, R; Chong Marín, FA; Collahuazo López, L; D'Ambrosio, L; De Lorenzo, S; de Vries, G; Dore, S; Gaga, M; Gualano, G; Kunst, H; Matteelli, A; Migliori, GB; Moschos, C; Palmieri, F; Papavasileiou, A; Payen, MC; Roby Arias, AJ; Scardigli, A; Skrahina, A; Solovic, I; Sotgiu, G; Spanevello, A; Sulis, G; Tadolini, M; Tiberi, S; Vargas Vasquez, D; Viggiani, P; White, V; Zumla, A1
Abdo Arbex, M; Akkerman, OW; Alarcon Arrascue, E; Alarcon Guizado, V; Aleksa, A; Alffenaar, JW; Artsukevich, J; Auchynka, V; Bonini, EH; Caminero, JA; Centis, R; Chong Marín, FA; Collahuazo López, L; D'Ambrosio, L; De Lorenzo, S; de Vries, G; Dore, S; Gaga, M; Gualano, G; Kunst, H; Matteelli, A; Migliori, GB; Moschos, C; Palmieri, F; Papavasileiou, A; Payen, MC; Piana, A; Roby Arias, AJ; Scardigli, A; Skrahina, A; Solovic, I; Sotgiu, G; Spanevello, A; Sulis, G; Tadolini, M; Tiberi, S; Vargas Vasquez, D; Viggiani, P; White, V; Zumla, A1
Aharonov, R; Bishai, WR; Cohen, KA; Conway, TC; El-Hay, T; Goldschmidt, Y; Munsamy, V; Pym, AS; Shaham, O; Weissbrod, O; Wyres, KL; Yanover, C1
Bell, DT; Chauhan, V; Kaushik, A; Kumar, P; Lamichhane, G; Stevens, RL; Xia, F1
Cavanaugh, JS; Cegielski, JP; Dalton, T; Ershova, J; Jou, R; Kurbatova, E; Wu, MH1
Raghunand, TR; Viswanathan, G; Yadav, S1
Clumeck, N; De Wit, S; Delforge, M; Mathys, V; Muylle, I; Payen, MC; Van den Wijngaert, S; Vandenberg, O1
Caminero, JA; Mishra, GP1
De Wit, S; Payen, MC1
Fugemann, F1
de Jager, VR; Diacon, AH; Muliaditan, M; van Brakel, E; van der Merwe, L; Vanker, N1
Bruyneel, L; Debaveye, Y; Decock, C; Peetermans, WE; Spriet, I; Ten Haaf, N; Van Wilder, A; Vanhaecht, K1
Abruzzi, J; Kopczynski, A; Montes, THM; Nedel, WL; Portela, LV; Rodolphi, MS; Strogulski, NR1
Arenere-Mendoza, M; Fernández-de-Gamarra-Martínez, E; Fernández-Polo, A; González-Suárez, S; Gutiérrez-Urbón, JM; Nicolás-Picó, J; Rodríguez-Mateos, ME; Sánchez-Yáñez, E1
Chen, J; Liu, W; Zhao, F1
Bandić-Pavlović, D; Barišić, I; Beader, N; Bedenić, B; Frančula-Zaninović, S; Krilanović, M; Pešorda, L; Schoenthaler, S; Veir, Z1
Caljon, B; Crombé, F; De Geyter, D; Demuyser, T; Janssen, T; Muyldermans, A; Piérard, D; Seyler, L; Vanstokstraeten, R; Wybo, I1
Adeleke, G; Egbagbe, E; Ejembi, J; Ettu, AO; Habib, A; Irowa, OO; Makanjuola, OB; Medugu, N; Mutiu, B; Ogunbosi, B; Ogunsola, F; Oladele, RO; Osinaike, T; Rotimi, V; Uwaezuoke, NS1

Reviews

1 review(s) available for clavulanic acid and meropenem

ArticleYear
Efficacy and safety of World Health Organization group 5 drugs for multidrug-resistant tuberculosis treatment.
    The European respiratory journal, 2015, Volume: 46, Issue:5

    Topics: Amoxicillin; Antitubercular Agents; Azithromycin; Cilastatin; Clarithromycin; Clavulanic Acid; HIV Infections; Humans; Imipenem; Isoxazoles; Macrolides; Meropenem; Mycobacterium tuberculosis; Oxazolidinones; Randomized Controlled Trials as Topic; Thienamycins; Thioridazine; Treatment Outcome; Tuberculosis, Multidrug-Resistant; World Health Organization

2015

Other Studies

63 other study(ies) available for clavulanic acid and meropenem

ArticleYear
Identification of the novel narrow-spectrum beta-lactamase SCO-1 in Acinetobacter spp. from Argentina.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6

    Topics: Acinetobacter; Acinetobacter Infections; Amino Acid Sequence; Anti-Bacterial Agents; Argentina; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Clavulanic Acid; Cloning, Molecular; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Sequence Analysis, DNA

2007
Biochemical Characterization of SFC-1, a class A carbapenem-hydrolyzing beta-lactamase.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12

    Topics: Aztreonam; beta-Lactamases; Carbapenems; Catalysis; Cephalosporins; Clavulanic Acid; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Hydrolysis; Kinetics; Molecular Weight; Penicillanic Acid; Penicillins; Recombinant Proteins; Serratia; Sulbactam; Tazobactam

2007
First occurrence of an IMP metallo-beta-lactamase in Aeromonas caviae: IMP-19 in an isolate from France.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12

    Topics: Aeromonas; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; France; Integrons; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Sequence Analysis, DNA; Substrate Specificity

2007
Genetic and biochemical characterization of OXA-63, a new class D beta-lactamase from Brachyspira pilosicoli BM4442.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:4

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Base Sequence; beta-Lactamases; Brachyspira; Cloning, Molecular; Diarrhea; Feces; Gram-Negative Bacterial Infections; Humans; Kinetics; Molecular Sequence Data; Oxacillin; Penicillin Resistance; Sequence Analysis, DNA

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Kinetic characterization of VIM-7, a divergent member of the VIM metallo-beta-lactamase family.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8

    Topics: Acremonium; Bacterial Proteins; beta-Lactamases; Catalysis; Catalytic Domain; Cefepime; Ceftazidime; Cephalosporins; Kinetics; Models, Molecular; Mutation; Penicillinase; Protein Structure, Tertiary; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity

2008
Novel chimeric beta-lactamase CTX-M-64, a hybrid of CTX-M-15-like and CTX-M-14 beta-lactamases, found in a Shigella sonnei strain resistant to various oxyimino-cephalosporins, including ceftazidime.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:1

    Topics: Amino Acid Sequence; beta-Lactamases; Blotting, Southern; Ceftazidime; Cephalosporins; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Polymerase Chain Reaction; Sequence Homology, Amino Acid; Shigella sonnei

2009
Genetic variability among ampC genes from acinetobacter genomic species 3.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:3

    Topics: Acinetobacter; Acinetobacter baumannii; Amino Acid Sequence; Ampicillin Resistance; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; Escherichia coli; Genes, Bacterial; Genetic Variation; Humans; Kinetics; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Spain

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:8

    Topics: Amino Acid Sequence; Amoxicillin; Ampicillin; Animals; Anti-Bacterial Agents; Base Sequence; beta-Lactam Resistance; beta-Lactamases; Blotting, Southern; Campylobacter jejuni; Carbenicillin; Cephalosporins; Chickens; Cloxacillin; Isoelectric Focusing; Mass Spectrometry; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillins; Piperacillin; Polymerase Chain Reaction; Sequence Alignment; Ticarcillin

2009
Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:12

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Carboxylic Ester Hydrolases; Cefotaxime; Cefuroxime; Cephalosporins; Cephalothin; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; India; Kinetics; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillins; Sequence Analysis, DNA; Sequence Homology, Amino Acid

2009
Novel ambler class A carbapenem-hydrolyzing beta-lactamase from a Pseudomonas fluorescens isolate from the Seine River, Paris, France.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Blotting, Southern; Cloning, Molecular; DNA, Bacterial; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; France; Fresh Water; Gram-Negative Bacteria; Health Surveys; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Pseudomonas fluorescens; Water Microbiology

2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
GES-13, a beta-lactamase variant possessing Lys-104 and Asn-170 in Pseudomonas aeruginosa.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:3

    Topics: Anti-Bacterial Agents; Aztreonam; beta-Lactamases; beta-Lactams; Cephalosporins; Genetic Variation; Humans; Integrons; Microbial Sensitivity Tests; Molecular Sequence Data; Pseudomonas aeruginosa; Pseudomonas Infections; Sequence Analysis, DNA

2010
Mutant prevention concentrations of four carbapenems against gram-negative rods.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:6

    Topics: Acinetobacter baumannii; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Carbapenems; Doripenem; Drug Resistance, Bacterial; Ertapenem; Escherichia coli; Genes, Bacterial; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Imipenem; In Vitro Techniques; Klebsiella pneumoniae; Meropenem; Microbial Sensitivity Tests; Mutation; Phenotype; Pseudomonas aeruginosa; Thienamycins

2010
Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:7

    Topics: Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Cephalosporinase; Clavulanic Acid; Computer Simulation; Enzyme Inhibitors; Hydrogen Bonding; Kinetics; Microbial Sensitivity Tests; Molecular Structure; Mutagenesis, Site-Directed; Penicillanic Acid; Protein Structure, Secondary; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity; Sulbactam; Tazobactam

2010
Extended-spectrum cephalosporinase in Acinetobacter baumannii.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:8

    Topics: Acinetobacter baumannii; Amino Acid Sequence; Amino Acid Substitution; Anti-Bacterial Agents; Aztreonam; Bacterial Proteins; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporin Resistance; Cephalosporinase; Cephalosporins; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Monobactams; Mutagenesis, Site-Directed

2010
Comparative biochemical and computational study of the role of naturally occurring mutations at Ambler positions 104 and 170 in GES β-lactamases.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:11

    Topics: Ampicillin; beta-Lactamases; Computational Biology; Escherichia coli; Hydrogen Bonding; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Protein Structure, Secondary; Ticarcillin

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Discovery of a Cyclic Boronic Acid β-Lactamase Inhibitor (RPX7009) with Utility vs Class A Serine Carbapenemases.
    Journal of medicinal chemistry, 2015, May-14, Volume: 58, Issue:9

    Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Boronic Acids; Carbapenems; Crystallography, X-Ray; Drug Resistance, Bacterial; Drug Synergism; Gram-Negative Bacteria; Heterocyclic Compounds, 1-Ring; Mice; Microbial Sensitivity Tests; Models, Molecular; Rats; Stereoisomerism; Structure-Activity Relationship

2015
Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- and Metallo-β-lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections.
    Journal of medicinal chemistry, 2020, 03-26, Volume: 63, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; beta-Lactam Resistance; beta-Lactamase Inhibitors; Borinic Acids; Carbapenems; Carboxylic Acids; Humans; Mice; Models, Molecular

2020
Susceptibilities of ESBL-producing Enterobacteriaceae to ertapenem, meropenem and piperacillin-tazobactam with and without clavulanic acid.
    Chemotherapy, 2007, Volume: 53, Issue:3

    Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Clavulanic Acid; Drug Interactions; Ertapenem; Escherichia coli; Klebsiella pneumoniae; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Thienamycins

2007
Meropenem-clavulanate is effective against extensively drug-resistant Mycobacterium tuberculosis.
    Science (New York, N.Y.), 2009, Feb-27, Volume: 323, Issue:5918

    Topics: Acylation; Antibiotics, Antitubercular; beta-Lactamase Inhibitors; beta-Lactamases; Catalytic Domain; Clavulanic Acid; Crystallography, X-Ray; Drug Combinations; Drug Resistance, Multiple, Bacterial; Enzyme Inhibitors; Extensively Drug-Resistant Tuberculosis; Humans; Kinetics; Mass Spectrometry; Meropenem; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Thienamycins

2009
Meropenem-clavulanate: a new strategy for the treatment of tuberculosis?
    ChemMedChem, 2009, Volume: 4, Issue:7

    Topics: Antitubercular Agents; beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Drug Therapy, Combination; Enzyme Inhibitors; Humans; Meropenem; Mycobacterium tuberculosis; Thienamycins; Tuberculosis

2009
Detection of the novel extended-spectrum beta-lactamase OXA-161 from a plasmid-located integron in Pseudomonas aeruginosa clinical isolates from Spain.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:12

    Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Clavulanic Acid; Gentamicins; Humans; Imipenem; Integrons; Meropenem; Molecular Sequence Data; Penicillanic Acid; Piperacillin; Plasmids; Pseudomonas aeruginosa; Pseudomonas Infections; Spain; Tazobactam; Thienamycins

2009
In vitro activity of ACH-702, a new isothiazoloquinolone, against Nocardia brasiliensis compared with econazole and the carbapenems imipenem and meropenem alone or in combination with clavulanic acid.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5

    Topics: Anti-Bacterial Agents; Clavulanic Acid; Drug Therapy, Combination; Econazole; Humans; Imipenem; In Vitro Techniques; Meropenem; Mycetoma; Nocardia; Nocardia Infections; Quinolones; Thiazoles; Thienamycins

2010
Meropenem/clavulanate and linezolid treatment for extensively drug-resistant tuberculosis.
    The Pediatric infectious disease journal, 2011, Volume: 30, Issue:9

    Topics: Acetamides; Adolescent; Antitubercular Agents; Clavulanic Acid; Extensively Drug-Resistant Tuberculosis; Female; Humans; Linezolid; Meropenem; Oxazolidinones; Thienamycins; Treatment Outcome

2011
Exploring the inhibition of CTX-M-9 by beta-lactamase inhibitors and carbapenems.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:7

    Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Carbapenems; Clavulanic Acid; Enzyme Inhibitors; Escherichia coli Proteins; Kinetics; Meropenem; Molecular Dynamics Simulation; Molecular Structure; Penicillanic Acid; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulbactam; Tazobactam; Thienamycins

2011
Clinical use of the meropenem-clavulanate combination for extensively drug-resistant tuberculosis.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2012, Volume: 16, Issue:4

    Topics: Adolescent; Adult; Antitubercular Agents; Clavulanic Acid; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Female; Humans; Male; Meropenem; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Salvage Therapy; Severity of Illness Index; Thienamycins; Treatment Outcome; Tuberculosis, Pulmonary; Young Adult

2012
Meropenem-clavulanic acid shows activity against Mycobacterium tuberculosis in vivo.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Cell Line; Clavulanic Acid; Drug Therapy, Combination; Macrophages; Meropenem; Mice; Mycobacterium tuberculosis; Thienamycins

2012
Class A carbapenemase FPH-1 from Francisella philomiragia.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:6

    Topics: Bacterial Proteins; beta-Lactamases; beta-Lactams; Carbapenems; Clavulanic Acid; Doripenem; Ertapenem; Escherichia coli; Francisella; Imipenem; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Sulbactam; Tazobactam; Thienamycins

2012
Inactivation of Mycobacterium tuberculosis l,d-transpeptidase LdtMt₁ by carbapenems and cephalosporins.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:8

    Topics: Anti-Bacterial Agents; Carbapenems; Cephalosporins; Clavulanic Acid; Extensively Drug-Resistant Tuberculosis; Meropenem; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Peptidoglycan; Peptidyl Transferases; Thienamycins

2012
Substitutions at position 105 in SHV family β-lactamases decrease catalytic efficiency and cause inhibitor resistance.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:11

    Topics: Amino Acid Substitution; Ampicillin; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Biocatalysis; Cephalosporins; Clavulanic Acid; Enzyme Inhibitors; Escherichia coli; Kinetics; Meropenem; Microbial Sensitivity Tests; Molecular Docking Simulation; Mutagenesis, Site-Directed; Structure-Activity Relationship; Substrate Specificity; Sulbactam; Thienamycins

2012
Efficacy and safety of meropenem-clavulanate added to linezolid-containing regimens in the treatment of MDR-/XDR-TB.
    The European respiratory journal, 2013, Volume: 41, Issue:6

    Topics: Acetamides; Adult; Antitubercular Agents; Case-Control Studies; Clavulanic Acid; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Female; Humans; Linezolid; Male; Meropenem; Middle Aged; Oxazolidinones; Thienamycins; Treatment Outcome; Tuberculosis, Multidrug-Resistant

2013
Is there a place for β-lactams in the treatment of multidrug-resistant/extensively drug-resistant tuberculosis? Synergy between meropenem and amoxicillin/clavulanate.
    The Journal of antimicrobial chemotherapy, 2013, Volume: 68, Issue:2

    Topics: Amoxicillin; Anti-Bacterial Agents; beta-Lactams; Clavulanic Acid; Drug Synergism; Humans; Meropenem; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Thienamycins; Tuberculosis, Multidrug-Resistant

2013
In vitro and in vivo efficacy of β-lactams against replicating and slowly growing/nonreplicating Mycobacterium tuberculosis.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:6

    Topics: Amoxicillin-Potassium Clavulanate Combination; Animals; Anti-Bacterial Agents; beta-Lactams; Clavulanic Acid; Disease Models, Animal; Drug Therapy, Combination; Female; Humans; Meropenem; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Streptomycin; Thienamycins; Treatment Outcome; Tuberculosis, Pulmonary

2013
A novel extended-spectrum β-lactamase, SGM-1, from an environmental isolate of Sphingobium sp.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:8

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Ceftazidime; Clavulanic Acid; Cloning, Molecular; Cysteine; Escherichia coli; Genes, Bacterial; Imipenem; Meropenem; Microbial Sensitivity Tests; Molecular Sequence Data; Sequence Analysis, Protein; Sphingomonadaceae; Thienamycins

2013
In vitro cross-linking of Mycobacterium tuberculosis peptidoglycan by L,D-transpeptidases and inactivation of these enzymes by carbapenems.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:12

    Topics: Antitubercular Agents; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Carbapenems; Cell Wall; Clavulanic Acid; Doripenem; Enzyme Assays; Ertapenem; Escherichia coli; Gene Expression; Imipenem; Kinetics; Meropenem; Mycobacterium tuberculosis; Peptidoglycan; Peptidyl Transferases; Recombinant Proteins; Thienamycins

2013
Can inhibitor-resistant substitutions in the Mycobacterium tuberculosis β-Lactamase BlaC lead to clavulanate resistance?: a biochemical rationale for the use of β-lactam-β-lactamase inhibitor combinations.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:12

    Topics: Amino Acid Substitution; Antitubercular Agents; beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Drug Therapy, Combination; Escherichia coli; Extensively Drug-Resistant Tuberculosis; Gene Expression; Humans; Meropenem; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Mycobacterium tuberculosis; Protein Engineering; Recombinant Proteins; Thienamycins

2013
Stability, compatibility and microbiological activity studies of meropenem-clavulanate potassium.
    The Journal of antibiotics, 2015, Volume: 68, Issue:1

    Topics: Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Clavulanic Acid; Drug Combinations; Drug Incompatibility; Drug Synergism; Listeria monocytogenes; Meropenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Solvents; Staphylococcus aureus; Temperature; Thienamycins

2015
Antimicrobial susceptibility and genetic characterisation of Burkholderia pseudomallei isolated from Malaysian patients.
    TheScientificWorldJournal, 2014, Volume: 2014

    Topics: Amoxicillin; Anti-Bacterial Agents; Bacterial Proteins; Burkholderia pseudomallei; Clavulanic Acid; DNA Fingerprinting; Drug Resistance, Bacterial; Gene Expression; Humans; Imipenem; Malaysia; Melioidosis; Membrane Transport Proteins; Meropenem; Microbial Sensitivity Tests; Thienamycins; Trimethoprim, Sulfamethoxazole Drug Combination

2014
Meropenem-clavulanic acid has high in vitro activity against multidrug-resistant Mycobacterium tuberculosis.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:6

    Topics: Antitubercular Agents; Clavulanic Acid; Meropenem; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Thienamycins; Tuberculosis, Multidrug-Resistant

2015
First series of patients with XDR and pre-XDR TB treated with regimens that included meropenen-clavulanate in Argentina.
    Archivos de bronconeumologia, 2015, Volume: 51, Issue:10

    Topics: Adult; Antitubercular Agents; Argentina; Clavulanic Acid; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Female; Humans; Male; Meropenem; Middle Aged; Mycobacterium tuberculosis; Peru; Retrospective Studies; Sputum; Thienamycins; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Uruguay; Young Adult

2015
In Vitro Activity of β-Lactams in Combination with β-Lactamase Inhibitors against Multidrug-Resistant Mycobacterium tuberculosis Isolates.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:1

    Topics: Amoxicillin; Anti-Bacterial Agents; beta-Lactamases; Clavulanic Acid; Drug Combinations; Drug Resistance, Multiple, Bacterial; Drug Synergism; Gene Expression; Humans; Meropenem; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Sulbactam; Thienamycins; Tuberculosis, Multidrug-Resistant

2016
Effectiveness and safety of meropenem/clavulanate-containing regimens in the treatment of MDR- and XDR-TB.
    The European respiratory journal, 2016, Volume: 47, Issue:4

    Topics: Adult; Antitubercular Agents; Clavulanic Acid; Extensively Drug-Resistant Tuberculosis; Female; Humans; Male; Meropenem; Retrospective Studies; Thienamycins; Treatment Outcome; Tuberculosis, Multidrug-Resistant

2016
Comparison of effectiveness and safety of imipenem/clavulanate- versus meropenem/clavulanate-containing regimens in the treatment of MDR- and XDR-TB.
    The European respiratory journal, 2016, Volume: 47, Issue:6

    Topics: Adult; Antitubercular Agents; Clavulanic Acid; Cohort Studies; Comparative Effectiveness Research; Drug Resistance, Bacterial; Extensively Drug-Resistant Tuberculosis; Female; Humans; Imipenem; Male; Meropenem; Middle Aged; Sputum; Thienamycins; Time Factors; Treatment Outcome; Tuberculosis, Multidrug-Resistant

2016
Meropenem-clavulanate has high in vitro activity against multidrug-resistant Mycobacterium tuberculosis.
    International journal of mycobacteriology, 2015, Volume: 4 Suppl 1

    Topics: Administration, Intravenous; Antitubercular Agents; beta-Lactamase Inhibitors; Clavulanic Acid; Humans; Meropenem; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Thienamycins; Tuberculosis, Multidrug-Resistant

2015
Paradoxical Hypersusceptibility of Drug-resistant Mycobacteriumtuberculosis to β-lactam Antibiotics.
    EBioMedicine, 2016, Volume: 9

    Topics: Amoxicillin; Anti-Bacterial Agents; Bayes Theorem; beta-Lactamases; Clavulanic Acid; Drug Resistance, Multiple, Bacterial; Genes, Bacterial; High-Throughput Nucleotide Sequencing; Humans; Meropenem; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Phylogeny; Sequence Analysis, DNA; Thienamycins; Tuberculosis

2016
Mutation in an Unannotated Protein Confers Carbapenem Resistance in Mycobacterium tuberculosis.
    Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:3

    Topics: Amino Acid Sequence; Amino Acid Substitution; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; beta-Lactam Resistance; Cephalosporins; Clavulanic Acid; DNA, Intergenic; Gene Expression; Genetic Loci; Humans; Meropenem; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Open Reading Frames; Protein Binding; Thienamycins; Tuberculosis, Multidrug-Resistant

2017
Susceptibilities of MDR Mycobacterium tuberculosis isolates to unconventional drugs compared with their reported pharmacokinetic/pharmacodynamic parameters.
    The Journal of antimicrobial chemotherapy, 2017, 06-01, Volume: 72, Issue:6

    Topics: Amoxicillin-Potassium Clavulanate Combination; Antitubercular Agents; beta-Lactamase Inhibitors; Clavulanic Acid; Clofazimine; Drug Discovery; Drug Resistance, Multiple, Bacterial; Humans; Leprostatic Agents; Meropenem; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Thienamycins; Tuberculosis, Multidrug-Resistant

2017
Identification of Mycobacterial Genes Involved in Antibiotic Sensitivity: Implications for the Treatment of Tuberculosis with β-Lactam-Containing Regimens.
    Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:7

    Topics: Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Clavulanic Acid; Dibenzothiepins; Drug Resistance, Microbial; Meropenem; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Thienamycins; Tuberculosis

2017
Meropenem-clavulanate for drug-resistant tuberculosis: a follow-up of relapse-free cases.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2018, 01-01, Volume: 22, Issue:1

    Topics: Adult; Antitubercular Agents; Clavulanic Acid; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Female; Follow-Up Studies; Humans; Male; Meropenem; Retrospective Studies; Time Factors; Treatment Outcome

2018
Low-dose amoxicillin-clavulanate in drug-resistant tuberculosis.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2018, 04-01, Volume: 22, Issue:4

    Topics: Amoxicillin-Potassium Clavulanate Combination; Clavulanic Acid; Follow-Up Studies; Humans; Meropenem; Tuberculosis, Multidrug-Resistant

2018
In Reply: Synergy between amoxicillin and meropenem/clavulanate in drug-resistant tuberculosis.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2018, 04-01, Volume: 22, Issue:4

    Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Clavulanic Acid; Humans; Meropenem; Tuberculosis, Multidrug-Resistant

2018
[Not Available].
    Kinderkrankenschwester : Organ der Sektion Kinderkrankenpflege, 2016, Volume: 35, Issue:8

    Topics: Antibiotics, Antitubercular; Child; Clavulanic Acid; Drug Therapy, Combination; Humans; Meropenem; Tuberculosis, Multidrug-Resistant

2016
Optimizing β-Lactams against Tuberculosis.
    American journal of respiratory and critical care medicine, 2020, 05-01, Volume: 201, Issue:9

    Topics: Administration, Intravenous; Administration, Oral; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Clavulanic Acid; Drug Combinations; Female; Humans; Male; Meropenem; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Practice Guidelines as Topic; Tuberculosis; World Health Organization

2020
Timeliness of administration of amoxicillin-clavulanic acid and meropenem in a large tertiary care centre.
    International journal of clinical pharmacy, 2021, Volume: 43, Issue:6

    Topics: Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Clavulanic Acid; Humans; Meropenem; Retrospective Studies; Tertiary Care Centers

2021
Antibiotic therapy does not alter mitochondrial bioenergetics in lymphocytes of patients with septic shock - A prospective cohort study.
    Mitochondrion, 2022, Volume: 66

    Topics: Amoxicillin; Anti-Bacterial Agents; Azithromycin; beta-Lactams; Clavulanic Acid; Energy Metabolism; Humans; Lymphocytes; Meropenem; Mitochondria; Piperacillin, Tazobactam Drug Combination; Polymyxins; Prospective Studies; Shock, Septic; Vancomycin

2022
PAUSATE Study: Prevalence and appropriateness of the use of antimicrobials in Spanish hospitals.
    Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria, 2022, 08-02, Volume: 46, Issue:5

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ceftriaxone; Clavulanic Acid; Cross-Sectional Studies; Hospitals; Humans; Meropenem; Piperacillin; Prevalence; Tazobactam

2022
Analysis of drug resistance genes of integrons in clinical isolates of Escherichia coli from elderly bloodstream infections.
    Cellular and molecular biology (Noisy-le-Grand, France), 2022, Jun-30, Volume: 68, Issue:6

    Topics: Aged; Amikacin; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cefoxitin; Clavulanic Acid; Drug Resistance; Escherichia coli; Escherichia coli Infections; Gentamicins; Humans; Integrons; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Minocycline; Sepsis; Ticarcillin; Trimethoprim, Sulfamethoxazole Drug Combination

2022
Evolution of Beta-Lactamases in Urinary Klebsiella pneumoniae Isolates from Croatia; from Extended-Spectrum Beta-Lactamases to Carbapenemases and Colistin Resistance.
    Current microbiology, 2022, Oct-15, Volume: 79, Issue:12

    Topics: Amoxicillin; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Cephalosporins; Ciprofloxacin; Clavulanic Acid; Colistin; Croatia; Humans; Imipenem; Klebsiella Infections; Klebsiella pneumoniae; Meropenem; Microbial Sensitivity Tests

2022
Genotypic resistance determined by whole genome sequencing versus phenotypic resistance in 234 Escherichia coli isolates.
    Scientific reports, 2023, 01-09, Volume: 13, Issue:1

    Topics: Amikacin; Amoxicillin; Anti-Bacterial Agents; Cefepime; Cefotaxime; Ceftazidime; Ciprofloxacin; Clavulanic Acid; Escherichia coli; Escherichia coli Infections; Genotype; Gentamicins; Humans; Meropenem; Microbial Sensitivity Tests; Phenotype; Piperacillin; Retrospective Studies; Tazobactam; Tobramycin; Whole Genome Sequencing

2023
Antibiotic Guidelines for Critically Ill Patients in Nigeria.
    West African journal of medicine, 2023, Sep-28, Volume: 40, Issue:9

    Topics: Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Ceftriaxone; Clavulanic Acid; Community-Acquired Infections; Critical Illness; Cross Infection; Fluconazole; Humans; Meropenem; Microbial Sensitivity Tests; Nigeria; Piperacillin, Tazobactam Drug Combination; Pneumonia; Prospective Studies; Urinary Tract Infections

2023