clavulanic acid has been researched along with imipenem, anhydrous in 70 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (11.43) | 18.7374 |
| 1990's | 10 (14.29) | 18.2507 |
| 2000's | 27 (38.57) | 29.6817 |
| 2010's | 23 (32.86) | 24.3611 |
| 2020's | 2 (2.86) | 2.80 |
| Authors | Studies |
|---|---|
| Aszodi, J; Bonnefoy, A; Collette, P; Lampilas, M; Mauvais, P; Rowlands, DA | 1 |
| Bonnet, R; Chanal, C; Delmas, J; Lesens, O; Robin, F; Schweitzer, C; Tournilhac, O | 1 |
| Aubert, D; Naas, T; Nordmann, P; Ozcan, A | 1 |
| Arlet, G; Loli, A; Miriagou, V; Papagiannitsis, CC; Tzelepi, E; Tzouvelekis, LS | 1 |
| Cattoir, V; Corvec, S; Drugeon, H; Faccone, D; Galas, M; Mugnier, P; Nordmann, P; Pasteran, F; Petroni, A; Poirel, L; Rapoport, M | 1 |
| Miriagou, V; Papagiannitsis, CC; Tzelepi, E; Tzouvelekis, LS | 1 |
| Bonnet, R; Brebion, A; Constantin, JM; Delmas, J; Dubois, D; Robin, F | 1 |
| Girlich, D; Leclercq, R; Naas, T; Nordmann, P | 1 |
| Correia, A; Domingues, MR; Domingues, P; Fonseca, F; Henriques, I; Saavedra, MJ; Samyn, B; Sarmento, AC; van Beeumen, J | 1 |
| Hawley, JS; Jorgensen, JH; Murray, CK | 1 |
| Bonnet, R; Neuwirth, C; Robin, F; Siebor, E | 1 |
| Courvalin, P; Decré, D; Høiby, EA; Meziane-Cherif, D; Périchon, B | 1 |
| Courvalin, P; Dupêchez, M; Galimand, M; Lambert, T; Meziane-Cherif, D | 1 |
| Bonnet, R; Caniça, M; Ferreira, E; Manageiro, V; Mendonça, N; Robin, F; Salgado, MJ | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Castanheira, M; Samuelsen, Ø; Spencer, J; Walsh, TR | 1 |
| Arakawa, Y; Ishikawa, K; Nagano, N; Nagano, Y; Wachino, J | 1 |
| Beceiro, A; Bou, G; Cisneros, JM; Fernández-Cuenca, F; Martínez-Martínez, L; Pachón, J; Pascual, A; Pérez, A; Rodríguez-Baño, J; Vila, J | 1 |
| Bonnet, R; Brisabois, A; Cloeckaert, A; Doublet, B; Fabre, L; Granier, SA; Robin, F; Weill, FX | 1 |
| Chanteperdrix, V; Croizé, J; Nordmann, P; Poirel, L; Potron, A | 1 |
| Ghori, S; Griggs, DJ; Johnson, MM; Mott, A; Peake, L; Piddock, LJ | 1 |
| Cho, HS; Giske, CG; Lee, K; Sundman, K; Toleman, MA; Walsh, TR; Yong, D | 1 |
| Bonnet, R; Casin, I; Doublet, B; Fabre, L; Le Fleche, A; Robin, F; Weill, FX | 1 |
| De Luca, F; Docquier, JD; Ide, L; Nordmann, P; Poirel, L; Rossolini, GM; Verlinde, A | 1 |
| Girlich, D; Nordmann, P; Poirel, L | 1 |
| Bethel, CR; Bonomo, RA; Distler, AM; Kasuboski, C; Papp-Wallace, KM; Taracila, M | 1 |
| Kotsakis, SD; Legakis, NJ; Miriagou, V; Papagiannitsis, CC; Tzelepi, E; Tzouvelekis, LS | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Appelbaum, PC; Credito, K; Kosowska-Shick, K | 1 |
| Bonomo, RA; Distler, AM; Endimiani, A; Hornick, JM; Hujer, AM; Hujer, KM; Papp-Wallace, KM; Taracila, M | 1 |
| Nordmann, P; Poirel, L; Rodríguez-Martínez, JM; Ronco, E | 1 |
| Kotsakis, SD; Miriagou, V; Tzelepi, E; Tzouvelekis, LS | 1 |
| Abendroth, J; Atkins, K; Boyer, SH; Clifton, MC; Dudley, MN; Durso, S; Griffith, DC; Hecker, SJ; Hirst, GC; King, P; Lomovskaya, O; Loutit, JS; Morgan, EE; Potts, KT; Raymond, A; Reddy, KR; Sabet, M; Sun, D; Tarazi, Z; Totrov, M; Tsivkovski, R | 1 |
| Jansen, A; Kresken, M; Rodloff, AC; Werner, H | 1 |
| Appelbaum, PC; Jacobs, MR; Spangler, SK | 2 |
| Brickley, X; Duval, J; Legrand, P; Orsoni, A; Soussy, CJ | 1 |
| Andrew, JH; Downes, J | 1 |
| Citron, DM; Goldstein, EJ | 1 |
| Roselle, GA | 1 |
| Henry, D; Ngui-Yen, J; Skidmore, AG; Smith, A; Smith, JA | 1 |
| Calderwood, SB; Gardella, A; Jacoby, GA; Moellering, RC; Philippon, AM | 1 |
| Frère, JM; Ghuysen, JM; Kelly, JA; Klein, D | 1 |
| Duez, C; Frère, JM; Ghuysen, JM; Kelly, JA | 1 |
| Jones, R; Satishchandran, V; Shapiro, T; Suh, B; Truant, AL | 1 |
| Chandy, M; Ebenezer, S; Jesudason, MV; Lalitha, MK | 1 |
| Jansen, GJ; Slootmaker-van der Meulen, G; Welling, G | 1 |
| Gannon, P; Mucciardi, N; Sesin, GP | 1 |
| Miller, LA; Poupard, JA; Rittenhouse, SF; Utrup, LJ | 1 |
| Bur, F; Donahue, PE; Luke, DR; Mintz, SJ; Smith, DL; Yellin, AE | 1 |
| Betriu, C; Gómez, M; Palau, ML; Picazo, JJ; Sánchez, A | 1 |
| Chuang, CL; Tsai, SH; Wu, JJ; Yan, JJ | 1 |
| Kong, HS; Xu, GY; Xu, XW; Yang, Q; Yu, YS; Zhong, BY | 1 |
| Jacoby, GA; Walker, VJ; Walsh, KE | 1 |
| Appelbaum, PC; Clark, CL; Ednie, LM; Kosowska-Shick, K | 1 |
| Albertí, S; Juan, C; Mulet, X; Oliver, A; Pérez, JL; Zamorano, L | 1 |
| Campos-Rivera, MP; Escalante-Fuentes, WG; Ocampo-Candiani, J; Pucci, MJ; Vera-Cabrera, L; Welsh, O | 1 |
| Antunes, NT; Frase, H; Toth, M; Vakulenko, SB; Vakulenko, V | 1 |
| Frase, H; Lamoureaux, TL; Toth, M; Vakulenko, SB; Vakulenko, V | 1 |
| Arthur, M; Cordillot, M; Dubée, V; Dubost, L; Hugonnet, JE; Mainardi, JL; Marie, A; Triboulet, S | 1 |
| Khosravi, Y; Mariappan, V; Ng, SL; Vadivelu, J; Vellasamy, KM | 1 |
| Debata, NK; Jena, J; Sahoo, RK; Subudhi, E | 1 |
| Butler-Laporte, G; Menzies, D; Winters, N | 1 |
| Akkerman, OW; Alarcon Arrascue, E; Alarcon Guizado, V; Aleksa, A; Alffenaar, JW; Arbex, MA; Artsukevich, J; Avchinko, V; Bonini, EH; Caminero, JA; Centis, R; Chong Marín, FA; Collahuazo López, L; D'Ambrosio, L; De Lorenzo, S; de Vries, G; Dore, S; Gaga, M; Gualano, G; Kunst, H; Matteelli, A; Migliori, GB; Moschos, C; Palmieri, F; Papavasileiou, A; Payen, MC; Piana, A; Roby Arias, AJ; Scardigli, A; Skrahina, A; Solovic, I; Sotgiu, G; Spanevello, A; Sulis, G; Tadolini, M; Tiberi, S; Vargas Vasquez, D; Viggiani, P; White, V; Zumla, A | 1 |
| Abdo Arbex, M; Akkerman, OW; Alarcon Arrascue, E; Alarcon Guizado, V; Aleksa, A; Alffenaar, JW; Artsukevich, J; Auchynka, V; Bonini, EH; Caminero, JA; Centis, R; Chong Marín, FA; Collahuazo López, L; D'Ambrosio, L; De Lorenzo, S; de Vries, G; Dore, S; Gaga, M; Gualano, G; Kunst, H; Matteelli, A; Migliori, GB; Moschos, C; Palmieri, F; Papavasileiou, A; Payen, MC; Piana, A; Roby Arias, AJ; Scardigli, A; Skrahina, A; Solovic, I; Sotgiu, G; Spanevello, A; Sulis, G; Tadolini, M; Tiberi, S; Vargas Vasquez, D; Viggiani, P; White, V; Zumla, A | 1 |
| Chmielewska, M; Cieplak, M; Hadzik-Blaszczyk, M; Krupa, R; Kur, Z; Lenartowicz, B; Wardyn, KA; Zycinska, K | 1 |
| Atrkar Roushan, Z; Ghaffarian, F; Hedayati, M; Mojtahedi, A; Sedigh Ebrahim-Saraie, H | 1 |
| Calderón, C; M Munita, J; Martínez, F; Olivares, B; R Campodonico, P; Rivas, L | 1 |
| Dong, L; Feng, Y; Lin, Q; Lin, T | 1 |
| Bandić-Pavlović, D; Barišić, I; Beader, N; Bedenić, B; Frančula-Zaninović, S; Krilanović, M; Pešorda, L; Schoenthaler, S; Veir, Z | 1 |
1 review(s) available for clavulanic acid and imipenem, anhydrous
| Article | Year |
|---|---|
Efficacy and safety of World Health Organization group 5 drugs for multidrug-resistant tuberculosis treatment.
Topics: Amoxicillin; Antitubercular Agents; Azithromycin; Cilastatin; Clarithromycin; Clavulanic Acid; HIV Infections; Humans; Imipenem; Isoxazoles; Macrolides; Meropenem; Mycobacterium tuberculosis; Oxazolidinones; Randomized Controlled Trials as Topic; Thienamycins; Thioridazine; Treatment Outcome; Tuberculosis, Multidrug-Resistant; World Health Organization | 2015 |
1 trial(s) available for clavulanic acid and imipenem, anhydrous
| Article | Year |
|---|---|
Trovafloxacin in the treatment of intra-abdominal infections: results of a double-blind, multicenter comparison with imipenem/cilastatin. Trovafloxacin Surgical Group.
Topics: Abdomen; Administration, Oral; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Cilastatin; Clavulanic Acid; Double-Blind Method; Female; Fluoroquinolones; Humans; Imipenem; Injections, Intravenous; Male; Middle Aged; Naphthyridines; Penicillins; Prospective Studies; Protease Inhibitors; Surgical Wound Infection; Thienamycins; Treatment Outcome | 1998 |
68 other study(ies) available for clavulanic acid and imipenem, anhydrous
| Article | Year |
|---|---|
Design and synthesis of bridged gamma-lactams as analogues of beta-lactam antibiotics.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; Bridged Bicyclo Compounds, Heterocyclic; Drug Design; Drug Stability; Gram-Negative Bacteria; Gram-Positive Bacteria; Inhibitory Concentration 50; Lactams; Microbial Sensitivity Tests; Penicillin-Binding Proteins; Structure-Activity Relationship | 2004 |
Evolution of TEM-type enzymes: biochemical and genetic characterization of two new complex mutant TEM enzymes, TEM-151 and TEM-152, from a single patient.
Topics: beta-Lactamases; Drug Resistance, Bacterial; Escherichia coli; Evolution, Molecular; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation | 2007 |
Chromosome-encoded narrow-spectrum Ambler class A beta-lactamase GIL-1 from Citrobacter gillenii.
Topics: beta-Lactamases; Chromosomes; Chromosomes, Bacterial; Citrobacter; Cloning, Molecular; DNA, Bacterial; Escherichia coli; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Genes, Bacterial; Molecular Sequence Data | 2007 |
SCO-1, a novel plasmid-mediated class A beta-lactamase with carbenicillinase characteristics from Escherichia coli.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Escherichia coli; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillinase; Plasmids; Sequence Analysis, DNA | 2007 |
Identification of the novel narrow-spectrum beta-lactamase SCO-1 in Acinetobacter spp. from Argentina.
Topics: Acinetobacter; Acinetobacter Infections; Amino Acid Sequence; Anti-Bacterial Agents; Argentina; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Clavulanic Acid; Cloning, Molecular; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Sequence Analysis, DNA | 2007 |
Plasmid-encoded ACC-4, an extended-spectrum cephalosporinase variant from Escherichia coli.
Topics: Anti-Bacterial Agents; Cephalosporinase; Culture Media; DNA Primers; Drug Resistance, Bacterial; Escherichia coli; Kinetics; Models, Molecular; Molecular Sequence Data; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; Spectrophotometry, Ultraviolet | 2007 |
TEM-158 (CMT-9), a new member of the CMT-type extended-spectrum beta-lactamases.
Topics: beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Catalysis; Ceftazidime; Clavulanic Acid; Escherichia coli; Escherichia coli Proteins; Isoenzymes; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Sequence Analysis, DNA | 2007 |
Molecular and biochemical characterization of the chromosome-encoded class A beta-lactamase BCL-1 from Bacillus clausii.
Topics: Amino Acid Sequence; Bacillus; Bacterial Proteins; beta-Lactamases; Chromosome Mapping; Chromosomes, Bacterial; Cloning, Molecular; Microbial Sensitivity Tests; Molecular Sequence Data; Molecular Weight; Sequence Homology, Amino Acid; Substrate Specificity | 2007 |
Biochemical Characterization of SFC-1, a class A carbapenem-hydrolyzing beta-lactamase.
Topics: Aztreonam; beta-Lactamases; Carbapenems; Catalysis; Cephalosporins; Clavulanic Acid; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Hydrolysis; Kinetics; Molecular Weight; Penicillanic Acid; Penicillins; Recombinant Proteins; Serratia; Sulbactam; Tazobactam | 2007 |
Development of colistin-dependent Acinetobacter baumannii-Acinetobacter calcoaceticus complex.
Topics: Acinetobacter baumannii; Acinetobacter calcoaceticus; Aged; Anti-Bacterial Agents; Bacteremia; Calcaneus; Colistin; Humans; Male; Microbial Sensitivity Tests; Osteomyelitis | 2007 |
First occurrence of an IMP metallo-beta-lactamase in Aeromonas caviae: IMP-19 in an isolate from France.
Topics: Aeromonas; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; France; Integrons; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Sequence Analysis, DNA; Substrate Specificity | 2007 |
Genetic and biochemical characterization of CAD-1, a chromosomally encoded new class A penicillinase from Carnobacterium divergens.
Topics: Amino Acid Sequence; beta-Lactams; Chromosomes, Bacterial; Cloning, Molecular; Electrophoresis, Gel, Pulsed-Field; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Infant, Newborn; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillin Resistance; Penicillinase; Sequence Alignment; Sequence Analysis, DNA; Substrate Specificity | 2008 |
Genetic and biochemical characterization of OXA-63, a new class D beta-lactamase from Brachyspira pilosicoli BM4442.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Base Sequence; beta-Lactamases; Brachyspira; Cloning, Molecular; Diarrhea; Feces; Gram-Negative Bacterial Infections; Humans; Kinetics; Molecular Sequence Data; Oxacillin; Penicillin Resistance; Sequence Analysis, DNA | 2008 |
The Lys234Arg substitution in the enzyme SHV-72 is a determinant for resistance to clavulanic acid inhibition.
Topics: Amino Acid Substitution; Amoxicillin; Anti-Bacterial Agents; Arginine; Aztreonam; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Clavulanic Acid; Computer Simulation; Imipenem; Isoelectric Focusing; Kinetics; Klebsiella pneumoniae; Lysine; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Penicillins; Protein Conformation; Protein Structure, Tertiary | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Kinetic characterization of VIM-7, a divergent member of the VIM metallo-beta-lactamase family.
Topics: Acremonium; Bacterial Proteins; beta-Lactamases; Catalysis; Catalytic Domain; Cefepime; Ceftazidime; Cephalosporins; Kinetics; Models, Molecular; Mutation; Penicillinase; Protein Structure, Tertiary; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity | 2008 |
Novel chimeric beta-lactamase CTX-M-64, a hybrid of CTX-M-15-like and CTX-M-14 beta-lactamases, found in a Shigella sonnei strain resistant to various oxyimino-cephalosporins, including ceftazidime.
Topics: Amino Acid Sequence; beta-Lactamases; Blotting, Southern; Ceftazidime; Cephalosporins; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Polymerase Chain Reaction; Sequence Homology, Amino Acid; Shigella sonnei | 2009 |
Genetic variability among ampC genes from acinetobacter genomic species 3.
Topics: Acinetobacter; Acinetobacter baumannii; Amino Acid Sequence; Ampicillin Resistance; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; Escherichia coli; Genes, Bacterial; Genetic Variation; Humans; Kinetics; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Spain | 2009 |
Novel plasmid-encoded ceftazidime-hydrolyzing CTX-M-53 extended-spectrum beta-lactamase from Salmonella enterica serotypes Westhampton and Senftenberg.
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Cardiidae; Ceftazidime; Ceftriaxone; Cephalosporin Resistance; Electrophoresis, Gel, Pulsed-Field; France; Microbial Sensitivity Tests; Plasmids; Polymerase Chain Reaction; Salmonella enterica; Serotyping | 2009 |
Genetic and biochemical characterization of the first extended-spectrum CARB-type beta-lactamase, RTG-4, from Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Drug Resistance, Bacterial; Escherichia coli; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Mutagenesis, Site-Directed | 2009 |
Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni.
Topics: Amino Acid Sequence; Amoxicillin; Ampicillin; Animals; Anti-Bacterial Agents; Base Sequence; beta-Lactam Resistance; beta-Lactamases; Blotting, Southern; Campylobacter jejuni; Carbenicillin; Cephalosporins; Chickens; Cloxacillin; Isoelectric Focusing; Mass Spectrometry; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillins; Piperacillin; Polymerase Chain Reaction; Sequence Alignment; Ticarcillin | 2009 |
Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Carboxylic Ester Hydrolases; Cefotaxime; Cefuroxime; Cephalosporins; Cephalothin; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; India; Kinetics; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillins; Sequence Analysis, DNA; Sequence Homology, Amino Acid | 2009 |
Molecular and biochemical characterization of the natural chromosome-encoded class A beta-lactamase from Pseudomonas luteola.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Catheters, Indwelling; Chromosomes, Bacterial; Cloning, Molecular; Electrophoresis, Gel, Pulsed-Field; Genes, Bacterial; Genetic Variation; Isoelectric Focusing; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Phylogeny; Plasmids; Pseudomonas; Pseudomonas Infections; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Substrate Specificity | 2010 |
BEL-2, an extended-spectrum beta-lactamase with increased activity toward expanded-spectrum cephalosporins in Pseudomonas aeruginosa.
Topics: Belgium; beta-Lactamases; Cephalosporinase; Cephalosporins; Cross Infection; Escherichia coli; Genes, Bacterial; Humans; Kinetics; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections | 2010 |
Novel ambler class A carbapenem-hydrolyzing beta-lactamase from a Pseudomonas fluorescens isolate from the Seine River, Paris, France.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Blotting, Southern; Cloning, Molecular; DNA, Bacterial; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; France; Fresh Water; Gram-Negative Bacteria; Health Surveys; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Pseudomonas fluorescens; Water Microbiology | 2010 |
Inhibitor resistance in the KPC-2 beta-lactamase, a preeminent property of this class A beta-lactamase.
Topics: Anti-Bacterial Agents; beta-Lactamases; Catalytic Domain; Clavulanic Acid; Computer Simulation; Enzyme Inhibitors; Kinetics; Microbial Sensitivity Tests; Penicillanic Acid; Spectrometry, Mass, Electrospray Ionization; Sulbactam; Tazobactam | 2010 |
GES-13, a beta-lactamase variant possessing Lys-104 and Asn-170 in Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Aztreonam; beta-Lactamases; beta-Lactams; Cephalosporins; Genetic Variation; Humans; Integrons; Microbial Sensitivity Tests; Molecular Sequence Data; Pseudomonas aeruginosa; Pseudomonas Infections; Sequence Analysis, DNA | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Mutant prevention concentrations of four carbapenems against gram-negative rods.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Carbapenems; Doripenem; Drug Resistance, Bacterial; Ertapenem; Escherichia coli; Genes, Bacterial; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Imipenem; In Vitro Techniques; Klebsiella pneumoniae; Meropenem; Microbial Sensitivity Tests; Mutation; Phenotype; Pseudomonas aeruginosa; Thienamycins | 2010 |
Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase.
Topics: Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Cephalosporinase; Clavulanic Acid; Computer Simulation; Enzyme Inhibitors; Hydrogen Bonding; Kinetics; Microbial Sensitivity Tests; Molecular Structure; Mutagenesis, Site-Directed; Penicillanic Acid; Protein Structure, Secondary; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity; Sulbactam; Tazobactam | 2010 |
Extended-spectrum cephalosporinase in Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Amino Acid Sequence; Amino Acid Substitution; Anti-Bacterial Agents; Aztreonam; Bacterial Proteins; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporin Resistance; Cephalosporinase; Cephalosporins; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Monobactams; Mutagenesis, Site-Directed | 2010 |
Comparative biochemical and computational study of the role of naturally occurring mutations at Ambler positions 104 and 170 in GES β-lactamases.
Topics: Ampicillin; beta-Lactamases; Computational Biology; Escherichia coli; Hydrogen Bonding; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Protein Structure, Secondary; Ticarcillin | 2010 |
Discovery of a Cyclic Boronic Acid β-Lactamase Inhibitor (RPX7009) with Utility vs Class A Serine Carbapenemases.
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Boronic Acids; Carbapenems; Crystallography, X-Ray; Drug Resistance, Bacterial; Drug Synergism; Gram-Negative Bacteria; Heterocyclic Compounds, 1-Ring; Mice; Microbial Sensitivity Tests; Models, Molecular; Rats; Stereoisomerism; Structure-Activity Relationship | 2015 |
German multicentre study on the in vitro susceptibility of Bacteroides species. The German Bacteroides Study Group.
Topics: Anti-Bacterial Agents; Bacteroides; Clavulanic Acid; Clavulanic Acids; Drug Resistance, Microbial; Humans; Imipenem; Metronidazole; Microbial Sensitivity Tests; Penicillins | 1992 |
Beta-lactamase production and susceptibilities to amoxicillin, amoxicillin-clavulanate, ticarcillin, ticarcillin-clavulanate, cefoxitin, imipenem, and metronidazole of 320 non-Bacteroides fragilis Bacteroides isolates and 129 fusobacteria from 28 U.S. cen
Topics: Amoxicillin; Anti-Bacterial Agents; Bacteroides; Bacteroides Infections; beta-Lactamase Inhibitors; beta-Lactamases; Cefoxitin; Clavulanic Acid; Clavulanic Acids; Fusobacterium; Fusobacterium Infections; Imipenem; Metronidazole; Microbial Sensitivity Tests; Ticarcillin; United States | 1990 |
Susceptibility of Bacteroides non-fragilis and fusobacteria to amoxicillin, amoxicillin/clavulanate, ticarcillin, ticarcillin/clavulanate, cefoxitin, imipenem and metronidazole.
Topics: Amoxicillin; Bacteroides; Cefoxitin; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Fusobacterium; Imipenem; Metronidazole; Microbial Sensitivity Tests; Ticarcillin | 1990 |
[Activity of 9 beta-lactam antibiotics combined with clavulanic acid or sulbactam against the strains of broad-spectrum beta-lactamase (CTX-1) producing Enterobacteriaceae isolated at the Henri Mondor Hospital].
Topics: Anti-Bacterial Agents; Aztreonam; beta-Lactamases; Cephalosporins; Citrobacter; Clavulanic Acid; Clavulanic Acids; Drug Resistance, Microbial; Drug Synergism; Enterobacter; Enterobacteriaceae; Escherichia coli; Humans; Imipenem; Klebsiella; Klebsiella pneumoniae; Microbial Sensitivity Tests; Sulbactam; Thienamycins | 1988 |
Susceptibility of 114 isolates of the Bacteroides fragilis group to imipenem and eight other antimicrobial agents.
Topics: Anti-Bacterial Agents; Bacteroides; Bacteroides fragilis; Cephalosporins; Clavulanic Acid; Clavulanic Acids; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Imipenem; Metronidazole; Microbial Sensitivity Tests; Penicillins; Ticarcillin | 1988 |
Comparative in vitro activities of amoxicillin-clavulanic acid and imipenem against anaerobic bacteria isolated from community hospitals.
Topics: Amoxicillin; Bacteria, Anaerobic; Clavulanic Acid; Clavulanic Acids; Cross Infection; Hospitals, Community; Humans; Imipenem; Microbial Sensitivity Tests; Thienamycins | 1986 |
Nosocomial and nursing home-acquired pneumonia. Recent therapeutic advances.
Topics: Anti-Bacterial Agents; Aztreonam; Cephalosporins; Cilastatin; Clavulanic Acid; Clavulanic Acids; Cross Infection; Cyclopropanes; Humans; Imipenem; Nursing Homes; Pneumonia; Thienamycins; Ticarcillin | 1987 |
In vitro activities of enoxacin, ticarcillin plus clavulanic acid, aztreonam, piperacillin, and imipenem and comparison with commonly used antimicrobial agents.
Topics: Anti-Bacterial Agents; Aztreonam; Clavulanic Acid; Clavulanic Acids; Enoxacin; Imipenem; Microbial Sensitivity Tests; Nalidixic Acid; Naphthyridines; Piperacillin; Species Specificity; Thienamycins; Ticarcillin | 1985 |
Effects of azlocillin in combination with clavulanic acid, sulbactam, and N-formimidoyl thienamycin against beta-lactamase-producing, carbenicillin-resistant Pseudomonas aeruginosa.
Topics: Azlocillin; beta-Lactamase Inhibitors; beta-Lactamases; Carbenicillin; Clavulanic Acid; Clavulanic Acids; Drug Interactions; Imipenem; Penicillanic Acid; Penicillin Resistance; Pseudomonas aeruginosa; Species Specificity; Sulbactam; Thienamycins | 1982 |
Interaction between non-classical beta-lactam compounds and the Zn2+-containing G and serine R61 and R39 D-alanyl-D-alanine peptidases.
Topics: Actinomycetaceae; Amdinocillin; beta-Lactams; Carboxypeptidases; Cefoxitin; Cephalosporins; Clavulanic Acid; Drug Interactions; Endopeptidases; Enzyme Inhibitors; Imipenem; Kinetics; Penicillanic Acid; Penicillins; Quinoxalines; Serine-Type D-Ala-D-Ala Carboxypeptidase; Streptomyces; Zinc | 1981 |
Interactions between non-classical beta-lactam compounds and the beta-lactamases of Actinomadura R39 and Streptomyces albus G.
Topics: Actinomycetaceae; Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactams; Clavulanic Acid; Hydrolysis; Imipenem; Kinetics; Streptomyces | 1981 |
In vitro activity of beta-lactamase inhibitors against clinical isolates of Acinetobacter species.
Topics: Acinetobacter; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamase Inhibitors; Cefotaxime; Ceftazidime; Ceftriaxone; Clavulanic Acid; Clavulanic Acids; Colony Count, Microbial; Imipenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Sensitivity and Specificity; Sulbactam; Tazobactam | 1995 |
In vitro evaluation of newer beta-lactam antibiotics against gram negative bacilli isolated from neutropenic patients.
Topics: Anti-Bacterial Agents; Azlocillin; Clavulanic Acid; Clavulanic Acids; Drug Evaluation; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Imipenem; Neutropenia; Piperacillin; Pseudomonas aeruginosa; Sepsis; Ticarcillin | 1994 |
Inactivation of imipenem by faecal fractions from human volunteers and the effect of clavulanate and cilastatin.
Topics: Anti-Bacterial Agents; Biotransformation; Cilastatin; Clavulanic Acid; Clavulanic Acids; Feces; Humans; Imipenem | 1993 |
Ticarcillin-clavulanate as an alternative to imipenem-cilastatin.
Topics: Bacterial Infections; Cilastatin; Clavulanic Acid; Clavulanic Acids; Drug Therapy, Combination; Humans; Imipenem; Protease Inhibitors; Ticarcillin | 1995 |
Evaluation of 500 gram negative isolates to determine the number of major susceptibility interpretation discrepancies between the Vitek and MicroScan Walkaway for 9 antimicrobial agents.
Topics: Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Clavulanic Acid; Clavulanic Acids; Enterobacter; Escherichia coli; Imipenem; Klebsiella pneumoniae; Mezlocillin; Microbial Sensitivity Tests; Norfloxacin; Penicillins; Piperacillin; Proteus mirabilis; Pseudomonas aeruginosa; Quality Control; Reproducibility of Results; Sulbactam; Thienamycins; Ticarcillin | 1996 |
In-vitro susceptibilities of species of the Bacteroides fragilis group to newer beta-lactam agents.
Topics: Amoxicillin; Ampicillin; Anti-Bacterial Agents; Bacteroides fragilis; beta-Lactamase Inhibitors; Cefoxitin; Ceftizoxime; Chloramphenicol; Clavulanic Acid; Clindamycin; Drug Therapy, Combination; Enzyme Inhibitors; Imipenem; Metronidazole; Mezlocillin; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Piperacillin; Species Specificity; Sulbactam; Tazobactam; Thienamycins; Ticarcillin | 1999 |
Comparison of the double-disk, combined disk, and Etest methods for detecting metallo-beta-lactamases in gram-negative bacilli.
Topics: Anti-Bacterial Agents; Bacteriological Techniques; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporins; Clavulanic Acid; Culture Media, Conditioned; Drug Resistance, Bacterial; Gram-Negative Bacteria; Humans; Imipenem; Microbial Sensitivity Tests; Sensitivity and Specificity | 2004 |
Typing and characterization of carbapenem-resistant Acinetobacter calcoaceticus-baumannii complex in a Chinese hospital.
Topics: Acinetobacter baumannii; Acinetobacter calcoaceticus; Acinetobacter Infections; Anti-Bacterial Agents; Bacterial Proteins; Bacterial Typing Techniques; beta-Lactam Resistance; beta-Lactamases; Carbapenems; China; Clavulanic Acid; Cloxacillin; Cross Infection; DNA Fingerprinting; DNA, Bacterial; Electrophoresis, Gel, Pulsed-Field; Enzyme Inhibitors; Genes, Bacterial; Genotype; Imipenem; Isoelectric Focusing; Isoelectric Point; Microbial Sensitivity Tests; Molecular Epidemiology; Sequence Analysis, DNA | 2004 |
Identification of extended-spectrum, AmpC, and carbapenem- hydrolyzing beta-lactamases in Escherichia coli and Klebsiella pneumoniae by disk tests.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Carbapenems; Cefoxitin; Clavulanic Acid; Edetic Acid; Escherichia coli; Humans; Hydrolysis; Imipenem; Klebsiella pneumoniae; Microbial Sensitivity Tests | 2006 |
Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies.
Topics: Anti-Bacterial Agents; Aza Compounds; Azithromycin; Clarithromycin; Clavulanic Acid; Clindamycin; Drug Resistance, Bacterial; Fluoroquinolones; Gemifloxacin; Imipenem; Ketolides; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Streptococcus pneumoniae | 2007 |
Detection of the novel extended-spectrum beta-lactamase OXA-161 from a plasmid-located integron in Pseudomonas aeruginosa clinical isolates from Spain.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Clavulanic Acid; Gentamicins; Humans; Imipenem; Integrons; Meropenem; Molecular Sequence Data; Penicillanic Acid; Piperacillin; Plasmids; Pseudomonas aeruginosa; Pseudomonas Infections; Spain; Tazobactam; Thienamycins | 2009 |
In vitro activity of ACH-702, a new isothiazoloquinolone, against Nocardia brasiliensis compared with econazole and the carbapenems imipenem and meropenem alone or in combination with clavulanic acid.
Topics: Anti-Bacterial Agents; Clavulanic Acid; Drug Therapy, Combination; Econazole; Humans; Imipenem; In Vitro Techniques; Meropenem; Mycetoma; Nocardia; Nocardia Infections; Quinolones; Thiazoles; Thienamycins | 2010 |
Class A carbapenemase FPH-1 from Francisella philomiragia.
Topics: Bacterial Proteins; beta-Lactamases; beta-Lactams; Carbapenems; Clavulanic Acid; Doripenem; Ertapenem; Escherichia coli; Francisella; Imipenem; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Sulbactam; Tazobactam; Thienamycins | 2012 |
A novel extended-spectrum β-lactamase, SGM-1, from an environmental isolate of Sphingobium sp.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Ceftazidime; Clavulanic Acid; Cloning, Molecular; Cysteine; Escherichia coli; Genes, Bacterial; Imipenem; Meropenem; Microbial Sensitivity Tests; Molecular Sequence Data; Sequence Analysis, Protein; Sphingomonadaceae; Thienamycins | 2013 |
In vitro cross-linking of Mycobacterium tuberculosis peptidoglycan by L,D-transpeptidases and inactivation of these enzymes by carbapenems.
Topics: Antitubercular Agents; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Carbapenems; Cell Wall; Clavulanic Acid; Doripenem; Enzyme Assays; Ertapenem; Escherichia coli; Gene Expression; Imipenem; Kinetics; Meropenem; Mycobacterium tuberculosis; Peptidoglycan; Peptidyl Transferases; Recombinant Proteins; Thienamycins | 2013 |
Antimicrobial susceptibility and genetic characterisation of Burkholderia pseudomallei isolated from Malaysian patients.
Topics: Amoxicillin; Anti-Bacterial Agents; Bacterial Proteins; Burkholderia pseudomallei; Clavulanic Acid; DNA Fingerprinting; Drug Resistance, Bacterial; Gene Expression; Humans; Imipenem; Malaysia; Melioidosis; Membrane Transport Proteins; Meropenem; Microbial Sensitivity Tests; Thienamycins; Trimethoprim, Sulfamethoxazole Drug Combination | 2014 |
Phylogenetic study of metallo-β-lactamase producing multidrug resistant Pseudomonas aeruginosa isolates from burn patients.
Topics: Amikacin; Anti-Bacterial Agents; beta-Lactamases; Burns; Ceftazidime; Ceftriaxone; Cilastatin; Clavulanic Acid; Colistin; Disk Diffusion Antimicrobial Tests; Drug Combinations; Drug Resistance, Multiple, Bacterial; Genetic Variation; Humans; Imipenem; Minocycline; Netilmicin; Ofloxacin; Phylogeny; Polymerase Chain Reaction; Pseudomonas aeruginosa; Tigecycline | 2015 |
Effectiveness and Safety of Imipenem-Clavulanate Added to an Optimized Background Regimen (OBR) Versus OBR Control Regimens in the Treatment of Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis.
Topics: Antitubercular Agents; Clavulanic Acid; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Humans; Imipenem; Treatment Outcome | 2016 |
Comparison of effectiveness and safety of imipenem/clavulanate- versus meropenem/clavulanate-containing regimens in the treatment of MDR- and XDR-TB.
Topics: Adult; Antitubercular Agents; Clavulanic Acid; Cohort Studies; Comparative Effectiveness Research; Drug Resistance, Bacterial; Extensively Drug-Resistant Tuberculosis; Female; Humans; Imipenem; Male; Meropenem; Middle Aged; Sputum; Thienamycins; Time Factors; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2016 |
Antibiotic Treatment of Hospitalized Patients with Pneumonia Complicated by Clostridium Difficile Infection.
Topics: Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Ceftriaxone; Cefuroxime; Ciprofloxacin; Clarithromycin; Clavulanic Acid; Clostridioides difficile; Clostridium Infections; Cross Infection; Female; Hospitalization; Host-Pathogen Interactions; Humans; Imipenem; Male; Pneumonia; Retrospective Studies; Treatment Outcome | 2016 |
Molecular epidemiology of ESBL-producing Klebsiella pneumoniae isolates in intensive care units of a tertiary care hospital, North of Iran.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Child; Child, Preschool; Clavulanic Acid; Cross-Sectional Studies; Drug Resistance, Multiple, Bacterial; Female; Humans; Imipenem; Intensive Care Units; Iran; Klebsiella Infections; Klebsiella pneumoniae; Male; Microbial Sensitivity Tests; Middle Aged; Molecular Epidemiology; Nalidixic Acid; Tertiary Care Centers | 2018 |
A Natural Deep Eutectic Solvent Formulated to Stabilize β-Lactam Antibiotics.
Topics: Anti-Bacterial Agents; beta-Lactams; Betaine; Carbon-13 Magnetic Resonance Spectroscopy; Clavulanic Acid; Escherichia coli; Imipenem; Microbial Sensitivity Tests; Proton Magnetic Resonance Spectroscopy; Pseudomonas aeruginosa; Solvents; Spectroscopy, Fourier Transform Infrared; Urea; Vibration; Water | 2018 |
Respiratory Care of Big Data Communication to Prevent Respiratory Tract Infection Nursing Analysis of Patients with Heart Failure.
Topics: Anti-Bacterial Agents; Big Data; Ceftazidime; Clavulanic Acid; Communication; Heart Failure; Humans; Imipenem; Microbial Sensitivity Tests; Piperacillin; Respiratory Tract Infections | 2022 |
Evolution of Beta-Lactamases in Urinary Klebsiella pneumoniae Isolates from Croatia; from Extended-Spectrum Beta-Lactamases to Carbapenemases and Colistin Resistance.
Topics: Amoxicillin; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Cephalosporins; Ciprofloxacin; Clavulanic Acid; Colistin; Croatia; Humans; Imipenem; Klebsiella Infections; Klebsiella pneumoniae; Meropenem; Microbial Sensitivity Tests | 2022 |