Page last updated: 2024-08-23

clavulanic acid and amoxicillin-potassium clavulanate combination

clavulanic acid has been researched along with amoxicillin-potassium clavulanate combination in 74 studies

Research

Studies (74)

Timeframe	Studies, this research(%)	All Research%
pre-1990	18 (24.32)	18.7374
1990's	12 (16.22)	18.2507
2000's	13 (17.57)	29.6817
2010's	17 (22.97)	24.3611
2020's	14 (18.92)	2.80

Authors

Authors	Studies
Rolinson, JN	1
Robinson, OP	1
Bingen, E; Bourgeois, F; Chardon, H; Doit, C; Lambert-Zechovsky, N	1
Brown, BA; Pang, Y; Steele, LC; Steingrube, VA; Wallace, RJ; Zeluff, B; Zhang, Y	1
Berry, V; Kernutt, I; Mizen, L; Woodnutt, G	1
Cooper, CE; Slocombe, B; White, AR	2
Appelbaum, PC; Jacobs, MR; Spangler, SK	1
Conner, CS	1
Eggleston, M; Parker, RH	1
Duval, J; Le Van Thoi, J; Soussy, CJ	1
Boon, R; Davies, BE; Descoeudres, CE; Horton, R; Reubi, FC	1
Bhattacharya, CP; Charkrabarty, AN; Dastidar, SG	1
Beale, AS; Boon, RJ	1
Von Kobyletzki, V	1
Clarke, HL; Horton, R; Jackson, D; Lau, D; Staniforth, DH	1
Casey, PA; Gstraunthaler, G; Pfaller, W; Semenitz, E	1
Davies, B; Horton, R; Jackson, D; Staniforth, DH	1
Barry, AL; Fuchs, PC; Gavan, TL; Jones, RN; Thornsberry, C	1
Casey, PA; Cooper, DL; Schaad, UB	1
Rolinson, GN	1
Hatzimichelakis, N; Kontomichalou, P; Makris, G; Paniara-Volika, O; Paraskevopoulou, E; Saroglou, G; Sima, A; Vassilopoulos, N	1
Ulmer, WT; Zimmermann, I	1
Bedenić, B; Zagar, Z	1
Butruk, E; Habior, A; Walewska-Zielecka, B	1
Amyes, SG; Miles, RS; Thomson, CJ	1
Carceles, CM; Escudero, E; Vicente, S	1
Aguilar, L; Balcabao, IP; Dal-Ré, R; Gómez-Lus, ML; Martín, M; Prieto, J	1
Pajchel, G; Pawłowski, K; Tyski, S	1
Bruynzeel, DP; Kamphof, WG; Rustemeyer, T	1
Denis, J; Frances, C; Hoizey, G; Kaltenbach, M; Lamiable, D; Millart, H; Trenque, T	1
Dammers, E; Exler, PS; Vree, TB	1
Dammers, E; Van Duuren, E; Vree, TB	2
Berry, V; Hoover, J; Singley, C; Woodnutt, G	1
Benyamini, L; Berkovitch, M; Bortnik, O; Braunstein, R; Bulkowstein, M; Merlob, P; Stahl, B; Zimmerman, D	1
Sánchez Navarro, A	1
Slocombe, B; Stokes, DH; Sutherland, R; Wilkinson, MJ	1
Callao, MP; Pasamontes, A	1
Chaowagul, W; Chierakul, W; Dance, DA; Day, NP; Lindegardh, N; Maharjan, B; Peacock, SJ; Pongtavornpinyo, W; Short, JM; Singtoroj, T; Teparrukkul, P; Wangboonskul, J; White, NJ; Wuthiekanun, V	1
Sunderland, VB; Vahdat, L	1
Kim, YH; Kim, YS; Ko, JY; Ro, YS	1
Ariza, A; Blanca, M; Blanca-Lopez, N; Doña, I; Mayorga, C; Rondon, C; Torres, MJ	1
Al-Karadsheh, OA; Algarugly, SA; Baqain, ZH; Eimar, HA; Karaky, AE; Sawair, FA	1
Baquero, F; Cantón, R; Galán, JC; Novais, A; Ripoll, A; Rodríguez-Domínguez, MJ; Turrientes, MC	1
Cercenado, E; de Toro, M; García-Campello, M; Rojo-Bezares, B; Sáenz, Y; Torres, C; Undabeitia, E	1
Ahuja, V; Balasubramanian, V; Balganesh, M; Bhattacharjee, D; Dinesh, N; Ganguly, S; Kumar, N; Panduga, V; Parab, M; Ramachandran, V; Reddy, J; Shandil, R; Sharma, S; Solapure, S; Vishwas, KG	1
Dance, D	1
Al-Nesf, M; Ibrahim, W; Mobayed, H	1
Daly, AK; Farrell, J; Faulkner, L; Kim, SH; Naisbitt, DJ; Ogese, M; Park, BK; Pirmohamed, M; Saide, K; Tailor, A	1
Kamiya, E; Kamiya, K; Kamiya, Y; Natsume, T; Niwa, H; Niwa, M; Saito, A; Tokura, Y	1
Chlebicki, MP; Tan, CW	1
Cavanaugh, JS; Cegielski, JP; Dalton, T; Ershova, J; Jou, R; Kurbatova, E; Wu, MH	1
Beumer, J; Bhatnagar, S; Haralam, M; Hoberman, A; Jeong, JH; Kearney, DH; Kurs-Lasky, M; Martin, JM; Miah, MK; Muñiz, G; Nagg, JP; Paradise, JL; Pope, MA; Rockette, HE; Shaikh, N; Shope, TR; Venkataramanan, R; Zhao, W	1
Batard, E; Caillon, J; Chapelet, G; Javaudin, F; Marquet, A; Montassier, E; Vibet, MA	1
Caminero, JA; Mishra, GP	1
De Wit, S; Payen, MC	1
Ali, AA; Charoo, NA; Rahman, Z	1
Kreetapirom, P; Sompornrattanaphan, M; Taweechue, AJ; Theankeaw, O; Thongngarm, T; Wongsa, C	1
Daniel, S; Doron, M; Fishman, B; Koren, G; Levy, A; Lunenfeld, E	1
Amaral, L; Carneiro-Leão, L; Cernadas, JR	1
Choi, Y; Chung, JY; Jang, K; Lee, SW; Yoon, SH	1
Burdet, C; Carette, C; Crémieux, AC; Czernichow, S; Duval, X; El-Helali, N; Hammas, K; Massias, L; Mellon, G; Mentré, F	1
Bieberly, Z; KuKanich, B; KuKanich, K; Papich, MG; Woodruff, K	1
Bruyneel, L; Debaveye, Y; Decock, C; Peetermans, WE; Spriet, I; Ten Haaf, N; Van Wilder, A; Vanhaecht, K	1
Liu, XG; Wang, R	1
Bruco, MEF; Kennard, L; Mirakian, R; Rutkowski, K; Wagner, A; Wang, XM	1
Allegaert, K; Baartmans, MGA; den Butter, PCP; Driessen, GJA; Eijkemans, M; Hartwig, NG; Heidema, J; Keij, FM; Kenter, S; Kornelisse, RF; Meijssen, CB; Norbruis, OF; Qi, H; Reiss, IKM; Stam-Stigter, GM; Tramper-Stranders, GA; van Beek, RHT; van Dalen-Vink, I; van den Berg, MM; van der Meer-Kappelle, LH; van der Sluijs-Bens, J; van Driel, A; van Rooij, LGM; van Rossem, MC; von Lindern, JS	1
Bio, LL; Yu, D	1
Baker, D; Guardabassi, L; Kovačević, Z; Liu, F; Page, SW; Pelligand, L; Scott, M; Sivagurunathan, A; Stair, JL; Steagall, PV; Suemanotham, N	1
Andrews, V; Ljungquist, O; Månsson, E; Tverring, J	1
Abbo, O; Bréhin, C; Claudet, I; Dubois, D; Lemoine, C; Munzer, C; Picard, C; Ricco, L	1
Aparin, PG; Emelyanova, AG; Ledov, VA; Petrova, NV; Tarasov, SA	1

Reviews

5 review(s) available for clavulanic acid and amoxicillin-potassium clavulanate combination

Article	Year
Beta-lactamase inhibitors: another approach to overcoming antimicrobial resistance. Infection control : IC, 1987, Volume: 8, Issue:1 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Humans; Kinetics; Penicillanic Acid; Penicillin Resistance; Penicillins; Sulbactam; Ticarcillin	1987
New formulations of amoxicillin/clavulanic acid: a pharmacokinetic and pharmacodynamic review. Clinical pharmacokinetics, 2005, Volume: 44, Issue:11 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Child; Clavulanic Acid; Computer Simulation; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Haemophilus influenzae; Humans; Moraxella catarrhalis; Streptococcus pneumoniae	2005
Treatment and prophylaxis of melioidosis. International journal of antimicrobial agents, 2014, Volume: 43, Issue:4 Topics: Administration, Oral; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Burkholderia pseudomallei; Carbapenems; Ceftazidime; Clavulanic Acid; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Humans; Infusions, Parenteral; Melioidosis; Sulfamethoxazole; Trimethoprim	2014
Efficacy of amoxicillin or amoxicillin and clavulanic acid in reducing infection rates after third molar surgery: a systematic review and meta-analysis. European review for medical and pharmacological sciences, 2022, Volume: 26, Issue:11 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Clavulanic Acid; Molar, Third; Randomized Controlled Trials as Topic; Surgical Wound Infection	2022
Shedding Light on Amoxicillin, Amoxicillin-clavulanate, and Cephalexin Dosing in Children from a Pharmacist's Perspective. Journal of the Pediatric Infectious Diseases Society, 2022, Dec-28, Volume: 11, Issue:12 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Cephalexin; Child; Clavulanic Acid; Humans; Microbial Sensitivity Tests; Pharmacists	2022

Trials

10 trial(s) available for clavulanic acid and amoxicillin-potassium clavulanate combination

Article	Year
A controlled trial of amoxycillin with clavulanic acid (BRL 25000) against doxycycline in chronic bronchitis. The Journal of international medical research, 1981, Volume: 9, Issue:5 Topics: Aged; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactams; Bronchitis; Clavulanic Acid; Clinical Trials as Topic; Doxycycline; Drug Combinations; Humans; Middle Aged	1981
Identical pattern of highly variable absorption of clavulanic acid from four different oral formulations of co-amoxiclav in healthy subjects. The Journal of antimicrobial chemotherapy, 2003, Volume: 51, Issue:2 Topics: Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Area Under Curve; Chemistry, Pharmaceutical; Chromatography, Liquid; Clavulanic Acid; Cross-Over Studies; Drug Therapy, Combination; Half-Life; Humans; Male; Mass Spectrometry	2003
Variable absorption of clavulanic acid after an oral dose of 25 mg/kg of Clavubactin and Synulox in healthy dogs. Journal of veterinary pharmacology and therapeutics, 2003, Volume: 26, Issue:3 Topics: Administration, Oral; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Animals; Area Under Curve; Clavulanic Acid; Cross-Over Studies; Dogs; Drug Combinations; Drug Therapy, Combination; Male; Reference Values	2003
Variable absorption of clavulanic acid after an oral dose of 25 mg/kg of Clavubactin and Synulox in healthy cats. TheScientificWorldJournal, 2002, May-21, Volume: 2 Topics: Administration, Oral; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Animals; Cats; Clavulanic Acid; Cross-Over Studies; Drug Evaluation; Drug Therapy, Combination; Fasting; Female; Tablets	2002
The safety of amoxicillin/clavulanic acid and cefuroxime during lactation. Therapeutic drug monitoring, 2005, Volume: 27, Issue:4 Topics: Adult; Alanine Transaminase; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Aspartate Aminotransferases; Breast Feeding; Cefuroxime; Clavulanic Acid; Diarrhea, Infantile; Dose-Response Relationship, Drug; Exanthema; Female; Humans; Infant; Lactation; Mastitis; Maternal Age; Middle Aged; Prospective Studies; Respiratory Tract Infections	2005
Clavulanic acid can be the component in amoxicillin-clavulanic acid responsible for immediate hypersensitivity reactions. The Journal of allergy and clinical immunology, 2010, Volume: 125, Issue:2 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Basophils; Clavulanic Acid; Drug Hypersensitivity; Humans; Single-Blind Method; Skin Tests	2010
Antibiotic prophylaxis and early dental implant failure: a quasi-random controlled clinical trial. European journal of oral implantology, 2011,Spring, Volume: 4, Issue:1 Topics: Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Analysis of Variance; Anti-Bacterial Agents; Antibiotic Prophylaxis; Chi-Square Distribution; Clavulanic Acid; Dental Implantation, Endosseous; Dental Restoration Failure; Drug Combinations; Female; Humans; Male; Middle Aged; Pain, Postoperative; Postoperative Care; Preoperative Care; Surgical Wound Dehiscence; Surgical Wound Infection	2011
Reduced-Concentration Clavulanate for Young Children with Acute Otitis Media. Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:7 Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Clavulanic Acid; Dermatitis; Diarrhea; Female; Humans; Infant; Infant, Newborn; Male; Otitis Media	2017
Multiple-dose pharmacokinetics and safety of amoxicillin/clavulanate in healthy elderly subjects. International journal of clinical pharmacology and therapeutics, 2020, Volume: 58, Issue:11 Topics: Aged; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Clavulanic Acid; Healthy Volunteers; Humans	2020
Efficacy and safety of switching from intravenous to oral antibiotics (amoxicillin-clavulanic acid) versus a full course of intravenous antibiotics in neonates with probable bacterial infection (RAIN): a multicentre, randomised, open-label, non-inferiorit The Lancet. Child & adolescent health, 2022, Volume: 6, Issue:11 Topics: Adolescent; Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bacterial Infections; Child; Child, Preschool; Clavulanic Acid; Humans; Infant; Infant, Newborn; Reinfection; Research; Treatment Outcome; Young Adult	2022

Other Studies

59 other study(ies) available for clavulanic acid and amoxicillin-potassium clavulanate combination

Article	Year
[The development of bacterial resistance and the role of clavulanic acid]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1992, Volume: 37, Issue:9 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bacteria; beta-Lactamase Inhibitors; Cell Membrane Permeability; Clavulanic Acid; Clavulanic Acids; Drug Resistance, Microbial; Drug Therapy, Combination; Mutation	1992
[The pharmacokinetics, dosage, tolerance, side effects and safety of the preparation Augmentin (a combination of amoxicillin and clavulanic acid)]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1992, Volume: 37, Issue:9 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Clavulanic Acid; Clavulanic Acids; Drug Evaluation; Drug Therapy, Combination; Drug Tolerance; Half-Life; Humans; Time Factors	1992
Killing kinetics of five orally administered antibiotics at clinically achievable concentrations against Moraxella catarrhalis. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1992, Volume: 11, Issue:10 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Cefaclor; Cefixime; Cefotaxime; Cefuroxime; Child; Clavulanic Acid; Clavulanic Acids; Colony Count, Microbial; Drug Combinations; Drug Therapy, Combination; Erythromycin; Humans; Microbial Sensitivity Tests; Moraxella catarrhalis	1992
Acquired resistance of Nocardia brasiliensis to clavulanic acid related to a change in beta-lactamase following therapy with amoxicillin-clavulanic acid. Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:3 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Clavulanic Acids; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Isoelectric Focusing; Microbial Sensitivity Tests; Nocardia; Nocardia Infections	1991
Penetration of amoxycillin, ticarcillin and clavulanic acid into lymph after intravenous infusion in rabbits to simulate human serum pharmacokinetics. The Journal of antimicrobial chemotherapy, 1990, Volume: 26, Issue:5 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Animals; Biological Assay; Clavulanic Acid; Clavulanic Acids; Drug Therapy, Combination; Humans; Infusions, Intravenous; Lymph; Rabbits; Ticarcillin	1990
Effect of low concentrations of clavulanic acid on the in-vitro activity of amoxycillin against beta-lactamase-producing Branhamella catarrhalis and Haemophilus influenzae. The Journal of antimicrobial chemotherapy, 1990, Volume: 26, Issue:3 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; beta-Lactamases; Clavulanic Acid; Clavulanic Acids; Drug Therapy, Combination; Haemophilus influenzae; Moraxella catarrhalis; Nephelometry and Turbidimetry; Time Factors	1990
Beta-lactamase production, beta-lactam sensitivity and resistance to synergy with clavulanate of 737 Bacteroides fragilis group organisms from thirty-three US centres. The Journal of antimicrobial chemotherapy, 1990, Volume: 26, Issue:3 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bacteroides fragilis; beta-Lactamases; Clavulanic Acid; Clavulanic Acids; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; Microbial Sensitivity Tests; Species Specificity; United States	1990
beta-Lactamase inhibitors. Drug intelligence & clinical pharmacy, 1985, Volume: 19, Issue:6 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Bacterial Infections; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Humans; Penicillanic Acid; Sulbactam	1985
[Sensitivity to clavulanic acid of Escherichia coli isolated at the Henri Mondor hospital in 1986 according to phenotypes of beta-lactam antibiotic resistance]. Pathologie-biologie, 1988, Volume: 36, Issue:5 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Carbenicillin; Cefotaxime; Cephalothin; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Drug Resistance, Microbial; Escherichia coli; Microbial Sensitivity Tests; Penicillin Resistance; Phenotype	1988
Pharmacokinetics of amoxycillin and clavulanic acid in haemodialysis patients following intravenous administration of Augmentin. British journal of clinical pharmacology, 1988, Volume: 26, Issue:4 Topics: Aged; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Clavulanic Acid; Clavulanic Acids; Female; Humans; Injections, Intravenous; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis	1988
Comparison of sensitivity of Mycobacterium spp. to combinations of clavulanic acid & penicillins with certain antitubercular agents. The Indian journal of medical research, 1988, Volume: 88 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Antitubercular Agents; Clavulanic Acid; Clavulanic Acids; Drug Therapy, Combination; Microbial Sensitivity Tests; Mycobacterium; Penicillins	1988
Response of Streptococcus pyogenes to therapy with amoxicillin or amoxicillin-clavulanic acid in a mouse model of mixed infection caused by Staphylococcus aureus and Streptococcus pyogenes. Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:8 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Animals; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Male; Mice; Microscopy, Electron, Scanning; Staphylococcal Infections; Staphylococcus aureus; Streptococcal Infections; Streptococcus pyogenes; Time Factors; Wound Infection	1987
Pharmacokinetic data in gynecological surgery using preoperative augmentin. Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1987, Volume: 6, Issue:2 Suppl Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Clavulanic Acid; Clavulanic Acids; Drug Therapy, Combination; Endometrium; Fallopian Tubes; Female; Genital Diseases, Female; Half-Life; Humans; Myometrium; Ovary; Postoperative Complications; Preoperative Care; Tissue Distribution	1987
Augmentin bioavailability following cimetidine, aluminum hydroxide and milk. International journal of clinical pharmacology, therapy, and toxicology, 1985, Volume: 23, Issue:3 Topics: Administration, Oral; Adult; Aluminum Hydroxide; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Animals; Cimetidine; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Drug Interactions; Humans; Metabolic Clearance Rate; Milk	1985
Clavulanic acid inhibits beta-lactamases. FDA drug bulletin, 1984, Volume: 14, Issue:3 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Drug Combinations; United States; United States Food and Drug Administration	1984
Microcalorimetric, turbidimetric, phase-contrast microscopic, and electron microscopic investigations of the actions of amoxicillin, clavulanic acid and augmentin on amoxicillin-sensitive and amoxicillin-resistant strains of Escherichia coli. Chemotherapy, 1983, Volume: 29, Issue:3 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Calorimetry; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Escherichia coli; Microscopy, Electron; Microscopy, Phase-Contrast; Nephelometry and Turbidimetry; Penicillin Resistance	1983
Parenteral augmentin: pharmacokinetics. International journal of clinical pharmacology, therapy, and toxicology, 1984, Volume: 22, Issue:8 Topics: Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Female; Half-Life; Humans; Hypoglycemic Agents; Infusions, Parenteral; Injections, Intravenous; Kinetics; Male; Probenecid	1984
In vitro evaluation of Augmentin by broth microdilution and disk diffusion susceptibility testing: regression analysis, tentative interpretive criteria, and quality control limits. Antimicrobial agents and chemotherapy, 1983, Volume: 24, Issue:1 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Ampicillin; Bacteria; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Microbial Sensitivity Tests; Quality Control; Regression Analysis	1983
Single-dose pharmacokinetics of intravenous clavulanic acid with amoxicillin in pediatric patients. Antimicrobial agents and chemotherapy, 1983, Volume: 23, Issue:2 Topics: Adolescent; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bacterial Infections; Child; Child, Preschool; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Female; Humans; Injections, Intravenous; Kinetics; Male	1983
The history and background of Augmentin. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1982, Jul-28, Volume: 62, Issue:5 Spec No Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Chemical Phenomena; Chemistry; Clavulanic Acid; Drug Combinations; Enzyme Inhibitors; Penicillin Resistance	1982
Amoxicillin and clavulanic acid combination: clinical and laboratory evaluation in pulmonary infections. Clinical therapeutics, 1982, Volume: 4, Issue:6 Topics: Adult; Aged; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; beta-Lactamases; beta-Lactams; Bronchitis; Clavulanic Acid; Drug Combinations; Humans; Microbial Sensitivity Tests; Middle Aged; Pneumonia	1982
Increased beta-lactamase activity in Branhamella catarrhalis after exposure to amoxicillin and clavulanic acid. Journal of chemotherapy (Florence, Italy), 1994, Volume: 6, Issue:6 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Clavulanic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Kinetics; Moraxella catarrhalis	1994
Hepatocellular-cholestatic liver injury due to amoxycillin-clavulanic acid combination. The Clinical investigator, 1994, Volume: 72, Issue:8 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Drug Therapy, Combination; Female; Granuloma; Humans; Male; Middle Aged; Respiratory Tract Infections; Tonsillitis	1994
Susceptibility testing with clavulanic acid: fixed concentration versus fixed ratio. Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:11 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Ampicillin Resistance; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Enzyme Inhibitors; Escherichia coli; Humans; Microbial Sensitivity Tests	1995
Pharmacokinetics of amoxicillin/clavulanic acid combination and of both drugs alone after intravenous administration to goats. The British veterinary journal, 1996, Volume: 152, Issue:5 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Animals; Anti-Bacterial Agents; Clavulanic Acid; Clavulanic Acids; Drug Therapy, Combination; Female; Goats; Half-Life; Injections, Intravenous; Penicillins	1996
In vitro assessment of the effect of clavulanic acid at concentrations achieved in human serum on the bactericidal activity of amoxicillin at physiological concentrations against Staphylococcus aureus: implications for dosage regimens. Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:6 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; beta-Lactamases; Clavulanic Acid; Clavulanic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Humans; Kinetics; Penicillins; Serum Bactericidal Test; Staphylococcus aureus	1997
CE versus LC for simultaneous determination of amoxicillin/clavulanic acid and ampicillin/sulbactam in pharmaceutical formulations for injections. Journal of pharmaceutical and biomedical analysis, 2002, Jun-20, Volume: 29, Issue:1-2 Topics: Amoxicillin-Potassium Clavulanate Combination; Ampicillin; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Clavulanic Acid; Drug Therapy, Combination; Electrophoresis, Capillary; Sulbactam	2002
Sensitization to clavulanic acid in Augmentin. Contact dermatitis, 2002, Volume: 47, Issue:1 Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Clavulanic Acid; Cystic Fibrosis; Diagnosis, Differential; Drug Eruptions; Female; Humans; Infant; Intradermal Tests; Patch Tests; Pneumonia	2002
Simultaneous determination of amoxicillin and clavulanic acid in human plasma by HPLC with UV detection. Journal of pharmaceutical and biomedical analysis, 2002, Oct-15, Volume: 30, Issue:3 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Chromatography, High Pressure Liquid; Clavulanic Acid; Humans; Male; Spectrophotometry, Ultraviolet	2002
Comparative bacteriological efficacy of pharmacokinetically enhanced amoxicillin-clavulanate against Streptococcus pneumoniae with elevated amoxicillin MICs and Haemophilus influenzae. Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:3 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Animals; Azithromycin; Clavulanic Acid; Haemophilus influenzae; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Rats; Rats, Sprague-Dawley; Streptococcus pneumoniae	2005
Bactericidal effects of amoxycillin/clavulanic acid (augmentin) against Legionella pneumophila in vitro and in tissue culture studies. Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Animals; Cells, Cultured; Clavulanic Acid; Legionella pneumophila; Legionnaires' Disease; Microbial Sensitivity Tests	1989
Activity of amoxycillin/clavulanic acid (augmentin) against beta-lactamase-positive S. aureus, H. influenzae and B. catarrhalis in an in vitro kinetic model. Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; beta-Lactamases; Clavulanic Acid; Haemophilus influenzae; Microbial Sensitivity Tests; Moraxella catarrhalis; Staphylococcus aureus	1989
Sequential injection analysis for the simultaneous determination of clavulanic acid and amoxicillin in pharmaceuticals using second-order calibration. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2006, Volume: 22, Issue:1 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Calibration; Clavulanic Acid; Flow Injection Analysis; Molecular Conformation; Pharmaceutical Preparations; Sensitivity and Specificity	2006
Pharmacokinetic and pharmacodynamic assessment of co-amoxiclav in the treatment of melioidosis. The Journal of antimicrobial chemotherapy, 2006, Volume: 58, Issue:6 Topics: Adolescent; Adult; Aged; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Clavulanic Acid; Humans; Melioidosis; Middle Aged; Time Factors	2006
Kinetics of amoxicillin and clavulanate degradation alone and in combination in aqueous solution under frozen conditions. International journal of pharmaceutics, 2007, Sep-05, Volume: 342, Issue:1-2 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Catalysis; Chemical Precipitation; Chromatography, High Pressure Liquid; Clavulanic Acid; Drug Combinations; Drug Stability; Freezing; Hydrochloric Acid; Hydrogen-Ion Concentration; Kinetics; Sodium Chloride; Solutions; Temperature	2007
A case of allergic contact dermatitis to clavulanic acid. Contact dermatitis, 2008, Volume: 59, Issue:6 Topics: Adult; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Clavulanic Acid; Dermatitis, Allergic Contact; Female; Hand Dermatoses; Humans; Patch Tests	2008
In vitro selection of variants resistant to beta-lactams plus beta-lactamase inhibitors in CTX-M beta-lactamases: predicting the in vivo scenario? Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:10 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; beta-Lactamases; Cefotaxime; Ceftazidime; Cephalosporin Resistance; Clavulanic Acid; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Evolution, Molecular; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Penicillanic Acid; Piperacillin; Plasmids; Selection, Genetic; Tazobactam	2011
Genetic characterization of the mechanisms of resistance to amoxicillin/clavulanate and third-generation cephalosporins in Salmonella enterica from three Spanish hospitals. International microbiology : the official journal of the Spanish Society for Microbiology, 2011, Volume: 14, Issue:3 Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Cephalosporins; Clavulanic Acid; Cross Infection; Electrophoresis, Gel, Pulsed-Field; Hospitals; Humans; Integrons; Microbial Sensitivity Tests; Polymerase Chain Reaction; Salmonella enterica; Salmonella Infections; Spain	2011
In vitro and in vivo efficacy of β-lactams against replicating and slowly growing/nonreplicating Mycobacterium tuberculosis. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:6 Topics: Amoxicillin-Potassium Clavulanate Combination; Animals; Anti-Bacterial Agents; beta-Lactams; Clavulanic Acid; Disease Models, Animal; Drug Therapy, Combination; Female; Humans; Meropenem; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Streptomycin; Thienamycins; Treatment Outcome; Tuberculosis, Pulmonary	2013
Delayed clavulanic acid-induced anaphylaxis in a patient undergoing bariatric surgery. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2014, Volume: 113, Issue:3 Topics: Adult; Amoxicillin-Potassium Clavulanate Combination; Anaphylaxis; Clavulanic Acid; Drug Hypersensitivity; Epinephrine; Humans; Hypersensitivity, Delayed; Male; Treatment Outcome	2014
Characterization of amoxicillin- and clavulanic acid-specific T cells in patients with amoxicillin-clavulanate-induced liver injury. Hepatology (Baltimore, Md.), 2015, Volume: 62, Issue:3 Topics: Aged; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Case-Control Studies; Cell Proliferation; Cells, Cultured; Chemical and Drug Induced Liver Injury; Clavulanic Acid; Clone Cells; Female; Humans; Leukocytes, Mononuclear; Lymphocyte Activation; Male; Middle Aged; Reference Values; Sampling Studies	2015
Drug eruption to clavulanic acid with sparing of cellulitis-affecting site. Allergology international : official journal of the Japanese Society of Allergology, 2015, Volume: 64, Issue:3 Topics: Amoxicillin-Potassium Clavulanate Combination; Cefazolin; Cellulitis; Clavulanic Acid; Drug Eruptions; Female; Humans; Japan; Middle Aged; Skin Tests; T-Lymphocytes; Withholding Treatment	2015
Urinary tract infections in adults. Singapore medical journal, 2016, Volume: 57, Issue:9 Topics: Adult; Aged; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Clavulanic Acid; Cystitis; Drug Resistance, Microbial; Escherichia coli; Escherichia coli Infections; Female; Humans; Incidence; Male; Middle Aged; Primary Health Care; Risk Factors; Urinary Tract Infections	2016
Susceptibilities of MDR Mycobacterium tuberculosis isolates to unconventional drugs compared with their reported pharmacokinetic/pharmacodynamic parameters. The Journal of antimicrobial chemotherapy, 2017, 06-01, Volume: 72, Issue:6 Topics: Amoxicillin-Potassium Clavulanate Combination; Antitubercular Agents; beta-Lactamase Inhibitors; Clavulanic Acid; Clofazimine; Drug Discovery; Drug Resistance, Multiple, Bacterial; Humans; Leprostatic Agents; Meropenem; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Thienamycins; Tuberculosis, Multidrug-Resistant	2017
Is There an Association Between Use of Amoxicillin-Clavulanate and Resistance to Third-Generation Cephalosporins in Klebsiella pneumoniae and Escherichia coli at the Hospital Level? Microbial drug resistance (Larchmont, N.Y.), 2018, Volume: 24, Issue:7 Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Clavulanic Acid; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Infections; Humans; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests	2018
Low-dose amoxicillin-clavulanate in drug-resistant tuberculosis. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2018, 04-01, Volume: 22, Issue:4 Topics: Amoxicillin-Potassium Clavulanate Combination; Clavulanic Acid; Follow-Up Studies; Humans; Meropenem; Tuberculosis, Multidrug-Resistant	2018
In Reply: Synergy between amoxicillin and meropenem/clavulanate in drug-resistant tuberculosis. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2018, 04-01, Volume: 22, Issue:4 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Clavulanic Acid; Humans; Meropenem; Tuberculosis, Multidrug-Resistant	2018
Is the demonstration of bioequivalence for clavulanic acid required in amoxicillin-clavulanic acid orally administered immediate-release products? The Journal of pharmacy and pharmacology, 2018, Volume: 70, Issue:7 Topics: Administration, Oral; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Clavulanic Acid; Humans; Microbial Sensitivity Tests; Therapeutic Equivalency	2018
Fatal anaphylaxis from a second amoxicillin/clavulanic acid provocation after a prior negative provocation. The journal of allergy and clinical immunology. In practice, 2020, Volume: 8, Issue:2 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anaphylaxis; Anti-Bacterial Agents; Clavulanic Acid; Humans	2020
The safety of amoxicillin and clavulanic acid use during the first trimester of pregnancy. British journal of clinical pharmacology, 2019, Volume: 85, Issue:12 Topics: Abnormalities, Drug-Induced; Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Clavulanic Acid; Cohort Studies; Dose-Response Relationship, Drug; Female; Humans; Infant, Newborn; Multivariate Analysis; Pregnancy; Pregnancy Trimester, First; Retrospective Studies; Risk Factors	2019
Acute Generalized Exanthematous Pustulosis Due to Clavulanic Acid. The journal of allergy and clinical immunology. In practice, 2020, Volume: 8, Issue:3 Topics: Acute Generalized Exanthematous Pustulosis; Amoxicillin-Potassium Clavulanate Combination; Clavulanic Acid; Humans	2020
Population pharmacokinetics and dosing simulations of amoxicillin in obese adults receiving co-amoxiclav. The Journal of antimicrobial chemotherapy, 2020, 12-01, Volume: 75, Issue:12 Topics: Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Clavulanic Acid; Humans; Obesity; Prospective Studies	2020
Evaluation of urine concentrations of amoxicillin and clavulanate in cats. Journal of veterinary internal medicine, 2021, Volume: 35, Issue:1 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Animals; Anti-Bacterial Agents; Clavulanic Acid; Dogs; Escherichia coli; Microbial Sensitivity Tests	2021
Timeliness of administration of amoxicillin-clavulanic acid and meropenem in a large tertiary care centre. International journal of clinical pharmacy, 2021, Volume: 43, Issue:6 Topics: Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Clavulanic Acid; Humans; Meropenem; Retrospective Studies; Tertiary Care Centers	2021
Amoxicillin hypersensitivity: Patient outcomes in a seven-year retrospective study. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2022, Volume: 129, Issue:4 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Clavulanic Acid; Drug Hypersensitivity; Humans; Hypersensitivity, Immediate; Monobactams; Penicillin G; Penicillins; Retrospective Studies; Skin Tests	2022
Quality of amoxicillin/clavulanic acid oral formulations for intended veterinary use in the UK, Malaysia, Serbia and Thailand. The Journal of small animal practice, 2023, Volume: 64, Issue:10 Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Clavulanic Acid; Dogs; Malaysia; Prospective Studies; Serbia; Tablets; Thailand; United Kingdom	2023
Pivmecillinam with Amoxicillin/Clavulanic acid as step down oral therapy in febrile Urinary Tract Infections caused by ESBL-producing Enterobacterales (PACUTI). Trials, 2023, Sep-02, Volume: 24, Issue:1 Topics: Adult; Amdinocillin Pivoxil; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Clavulanic Acid; Fever; Humans; Urinary Tract Infections	2023
Non-operative treatment of acute appendicitis in children: clinical efficacy of amoxicillin-clavulanic acid in a retrospective single-centre study. BMJ paediatrics open, 2023, Volume: 7, Issue:1 Topics: Abscess; Acute Disease; Adolescent; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Appendicitis; Child; Child, Preschool; Clavulanic Acid; Cross-Sectional Studies; Humans; Peritonitis; Retrospective Studies; Treatment Outcome	2023
Efficacy of Raphamin against Pneumococcal Infection: a Preclinical Study. Bulletin of experimental biology and medicine, 2023, Volume: 175, Issue:5 Topics: Amoxicillin-Potassium Clavulanate Combination; Animals; Anti-Bacterial Agents; Clavulanic Acid; Mice; Pneumococcal Infections; Streptococcus pneumoniae	2023