clausine-e has been researched along with 7-methoxyheptaphylline* in 1 studies
1 other study(ies) available for clausine-e and 7-methoxyheptaphylline
Article | Year |
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Claurailas A-D, cytotoxic carbazole alkaloids from the roots of Clausena harmandiana.
Four new carbazole alkaloids, claurailas A-D (1-4), as well as 12 known carbazoles and three known coumarins were isolated from the roots of Clausena harmandiana. Heptaphylline (6) and 7-methoxyheptaphylline (7) showed strong cytotoxicity against NCI-H187 and KB cell lines with IC(50) values ranging from 1.3 to 2.7 μM. Compound 7 showed no cytotoxicity against Vero cells. Topics: Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Carbazoles; Chlorocebus aethiops; Clausena; Coumarins; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; KB Cells; Plant Roots | 2011 |