clasto-lactacystin beta-lactone has been researched along with marizomib in 8 studies
| Studies (clasto-lactacystin beta-lactone) | Trials (clasto-lactacystin beta-lactone) | Recent Studies (post-2010) (clasto-lactacystin beta-lactone) | Studies (marizomib) | Trials (marizomib) | Recent Studies (post-2010) (marizomib) |
|---|---|---|---|---|---|
| 85 | 0 | 15 | 127 | 4 | 64 |
| Protein | Taxonomy | clasto-lactacystin beta-lactone (IC50) | marizomib (IC50) |
|---|---|---|---|
| Proteasome subunit beta type-11 | Homo sapiens (human) | 0.0013 | |
| Proteasome subunit alpha type-7 | Homo sapiens (human) | 0.0013 | |
| Proteasome subunit beta type-1 | Homo sapiens (human) | 0.144 | |
| Proteasome subunit alpha type-1 | Homo sapiens (human) | 0.0013 | |
| Proteasome subunit alpha type-2 | Homo sapiens (human) | 0.0013 | |
| Proteasome subunit alpha type-3 | Homo sapiens (human) | 0.0013 | |
| Proteasome subunit alpha type-4 | Homo sapiens (human) | 0.0013 | |
| Proteasome subunit beta type-8 | Homo sapiens (human) | 0.0013 | |
| Proteasome subunit beta type-9 | Homo sapiens (human) | 0.0013 | |
| Proteasome subunit alpha type-5 | Homo sapiens (human) | 0.0013 | |
| Proteasome subunit beta type-4 | Homo sapiens (human) | 0.0013 | |
| Proteasome subunit beta type-6 | Homo sapiens (human) | 0.0013 | |
| Proteasome subunit beta type-5 | Homo sapiens (human) | 0.0076 | |
| Proteasome subunit beta type-10 | Homo sapiens (human) | 0.0013 | |
| Proteasome subunit beta type-3 | Homo sapiens (human) | 0.0013 | |
| Proteasome subunit beta type-2 | Homo sapiens (human) | 0.0147 | |
| Proteasome subunit alpha type-6 | Homo sapiens (human) | 0.0013 | |
| Proteasome subunit alpha-type 8 | Homo sapiens (human) | 0.0013 | |
| Proteasome subunit beta type-7 | Homo sapiens (human) | 0.0013 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Chao, TH; Deyanat-Yazdi, G; Fenical, WF; Jensen, PR; Lam, KS; Macherla, VR; Mai, B; Manam, RR; Mitchell, SS; Neuteboom, ST; Nicholson, B; Palladino, MA; Potts, BC; Reed, KA | 1 |
| Crews, P; Linington, RG; Navarro, G; Radjasa, OK; Tenney, K; Vaske, YM; Vervoort, HC | 1 |
| Arisawa, M; Asai, A; Groll, M; Kawamura, S; List, A; Mizuno, A; Sasaki, T; Shuto, S; Tanaka, M; Unno, Y | 1 |
| Cai, J; Chen, S; Li, K; Liu, Y; Pang, X; Zhang, X; Zhou, X; Zhu, Y | 1 |
| Corey, EJ; Fournier, JF; Reddy, BV; Reddy, LR | 1 |
| Corey, EJ; Fournier, JF; Reddy, LR; Subba Reddy, BV | 1 |
| Corey, EJ; Hogan, PC | 1 |
| Dring, CW; Lam, KS; Macherla, VR; Manam, RR; Neuteboom, ST; Potts, BC; Tsueng, G; Weiss, J | 1 |
2 review(s) available for clasto-lactacystin beta-lactone and marizomib
| Article | Year |
|---|---|
Highlights of marine invertebrate-derived biosynthetic products: their biomedical potential and possible production by microbial associants.
Topics: Animals; Aquatic Organisms; Biological Products; Biotechnology; Coral Reefs; Humans; Invertebrates | 2011 |
Natural products from mangrove sediments-derived microbes: Structural diversity, bioactivities, biosynthesis, and total synthesis.
Topics: Anti-Bacterial Agents; Biological Products; Ecosystem; Fungi; Streptomyces | 2022 |
6 other study(ies) available for clasto-lactacystin beta-lactone and marizomib
| Article | Year |
|---|---|
Structure-activity relationship studies of salinosporamide A (NPI-0052), a novel marine derived proteasome inhibitor.
Topics: Actinobacteria; Animals; Antineoplastic Agents; Cell Line; Cell Line, Tumor; Humans; Lactones; Marine Biology; NF-kappa B; Proteasome Inhibitors; Pyrroles; Rabbits; Stereoisomerism; Structure-Activity Relationship | 2005 |
Potent proteasome inhibitors derived from the unnatural cis-cyclopropane isomer of Belactosin A: synthesis, biological activity, and mode of action.
Topics: Cell Proliferation; Chemistry Techniques, Synthetic; Crystallography, X-Ray; Cyclopropanes; Drug Stability; HCT116 Cells; Humans; Intercellular Signaling Peptides and Proteins; Isomerism; Models, Molecular; Peptides; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Conformation; Water | 2013 |
New synthetic route for the enantioselective total synthesis of salinosporamide A and biologically active analogues.
Topics: Catalysis; Cyclization; Lactones; Molecular Structure; Pyrroles; Stereoisomerism | 2005 |
An efficient, stereocontrolled synthesis of a potent omuralide-salinosporin hybrid for selective proteasome inhibition.
Topics: Enzyme Inhibitors; Lactones; Molecular Conformation; Proteasome Inhibitors; Pyrroles; Stereoisomerism | 2005 |
Proteasome inhibition by a totally synthetic beta-lactam related to salinosporamide A and omuralide.
Topics: beta-Lactams; Drug Stability; Half-Life; Kinetics; Lactones; Proteasome Inhibitors; Pyrroles | 2005 |
Antiprotealide is a natural product.
Topics: Actinobacteria; Animals; Biological Products; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Lactams; Lactones; Marine Biology; Molecular Structure; Proteasome Endopeptidase Complex; Pyrroles; Rabbits | 2009 |