Page last updated: 2024-09-05

clasto-lactacystin beta-lactone and leupeptins

clasto-lactacystin beta-lactone has been researched along with leupeptins in 21 studies

Compound Research Comparison

Studies
(clasto-lactacystin beta-lactone)
Trials
(clasto-lactacystin beta-lactone)
Recent Studies (post-2010)
(clasto-lactacystin beta-lactone)
Studies
(leupeptins)
Trials
(leupeptins)
Recent Studies (post-2010) (leupeptins)
850153,89141,106

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.76)18.2507
2000's17 (80.95)29.6817
2010's3 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dasso, M; Everett, RD; Freemont, P; Kathoria, M; Orr, A; Parkinson, J; Saitoh, H1
Becker, J; Jeblick, W; Kauss, H; Kempf, R1
McBride, AA; Penrose, KJ1
Mizel, SB; Moors, MA1
Holmberg, CI; Illman, SA; Kallio, M; Mikhailov, A; Sistonen, L1
Nowell, TR; Shang, F; Taylor, A1
Calzoni, GL; Crinelli, R; Magnani, M; Scoccianti, V; Speranza, A1
Alves dos Santos, CM; Bu, G; Klumperman, J; Sachse, M; Strous, GJ; van Kerkhof, P1
Burrows, J; Hale, PD; Hidvegi, T; Perlmutter, DH; Schmidt, B; Teckman, JH1
Fuertes, G; Knecht, E; Villarroya, A1
Belbeoc'h, S; Bon, S; Massoulié, J1
de Bree, P; Govers, R; Rabelink, TJ1
Ancuta, P; Gabuzda, D; McPike, M; Mehle, A; Strack, B; Zhang, C1
Itoh, K; Kobayashi, A; Kumagai, T; Kusano, Y; Osada, S; Uchida, K; Usami, H; Yamamoto, M1
Chik, CL; Ho, AK; Price, DM; Terriff, DL1
Dosenko, VE; Moibenko, AA; Nagibin, VS; Tumanovskaya, LV; Vaage, J; Zagoriy, VY1
Bahat, A; Granot, Z; Melamed-Book, N; Orly, J1
Li, Z; Matsubara, K; Murayama, T; Sadanari, H; Tanaka, J; Yamada, R1
Anwar, A; Fujita, M; Norris, DA1
Cai, J; Lin, B; Qu, J; Snider, BJ; Sun, L; Wu, M; Wu, S1
Dahlmann, B; Dyck, Y; Eisenhardt, D; Felsenberg, J; Kloetzel, PM; Kloß, A1

Reviews

2 review(s) available for clasto-lactacystin beta-lactone and leupeptins

ArticleYear
Opposite effects of proteasome inhibitors in the adrenergic induction of arylalkylamine N-acetyltransferase in rat pinealocytes.
    Chronobiology international, 2006, Volume: 23, Issue:1-2

    Topics: Adrenergic Agents; Animals; Arylalkylamine N-Acetyltransferase; Lactones; Leupeptins; Models, Biological; Pineal Gland; Protease Inhibitors; Proteasome Inhibitors; Rats; Time Factors

2006
Turnover of StAR protein: roles for the proteasome and mitochondrial proteases.
    Molecular and cellular endocrinology, 2007, Volume: 265-266

    Topics: Animals; Humans; Lactones; Leupeptins; Mitochondria; Mitochondrial Membranes; Oligopeptides; Peptide Hydrolases; Phosphoproteins; Protease Inhibitors; Proteasome Endopeptidase Complex

2007

Other Studies

19 other study(ies) available for clasto-lactacystin beta-lactone and leupeptins

ArticleYear
The disruption of ND10 during herpes simplex virus infection correlates with the Vmw110- and proteasome-dependent loss of several PML isoforms.
    Journal of virology, 1998, Volume: 72, Issue:8

    Topics: Animals; Cell Line; Cricetinae; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Endopeptidases; Herpesvirus 1, Human; Humans; Immediate-Early Proteins; Isomerism; Lactones; Leupeptins; Multienzyme Complexes; Neoplasm Proteins; Nuclear Proteins; Promyelocytic Leukemia Protein; Proteasome Endopeptidase Complex; SUMO-1 Protein; Transcription Factors; Tumor Cells, Cultured; Tumor Suppressor Proteins; Ubiquitin Thiolesterase; Ubiquitin-Protein Ligases; Ubiquitin-Specific Peptidase 7; Ubiquitins

1998
Induction of competence for elicitation of defense responses in cucumber hypocotyls requires proteasome activity.
    The Plant journal : for cell and molecular biology, 2000, Volume: 21, Issue:3

    Topics: Adenosine Triphosphatases; Chitinases; Cucumis sativus; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Darkness; Growth Inhibitors; Hydrogen Peroxide; Hypocotyl; Lactones; Leupeptins; Light; Multienzyme Complexes; Proteasome Endopeptidase Complex; RNA, Messenger

2000
Proteasome-mediated degradation of the papillomavirus E2-TA protein is regulated by phosphorylation and can modulate viral genome copy number.
    Journal of virology, 2000, Volume: 74, Issue:13

    Topics: Alanine; Animals; Bovine papillomavirus 1; Cattle; Cell Line; Chlorocebus aethiops; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; DNA, Viral; Gene Dosage; Genome, Viral; Lactones; Leupeptins; Multienzyme Complexes; Mutagenesis, Site-Directed; Papilloma; Papillomavirus Infections; Phosphorylation; Proteasome Endopeptidase Complex; Serine; Viral Proteins; Warts

2000
Proteasome-mediated regulation of interleukin-1beta turnover and export in human monocytes.
    Journal of leukocyte biology, 2000, Volume: 68, Issue:1

    Topics: Acrylates; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Half-Life; Humans; Interleukin-1; Lactones; Leucine; Leukemia, Monocytic, Acute; Leupeptins; Lipopolysaccharides; Monocytes; Multienzyme Complexes; Neoplasm Proteins; Proteasome Endopeptidase Complex; Tumor Cells, Cultured

2000
Formation of nuclear HSF1 granules varies depending on stress stimuli.
    Cell stress & chaperones, 2000, Volume: 5, Issue:3

    Topics: Blotting, Western; Cell Nucleus Structures; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Heat Shock Transcription Factors; Heat-Shock Proteins; Heat-Shock Response; HeLa Cells; HSP70 Heat-Shock Proteins; Humans; K562 Cells; Lactones; Leupeptins; Microscopy, Fluorescence; Multienzyme Complexes; Phosphorylation; Promoter Regions, Genetic; Proteasome Endopeptidase Complex; Recombinant Proteins; Transcription Factors

2000
Removal of oxidatively damaged proteins from lens cells by the ubiquitin-proteasome pathway.
    Experimental eye research, 2001, Volume: 73, Issue:2

    Topics: Animals; Crystallins; Cysteine Proteinase Inhibitors; Lactones; Lens, Crystalline; Leupeptins; Membrane Proteins; Molecular Weight; Oxidative Stress; Peptide Hydrolases; Rabbits; Ubiquitins; Up-Regulation

2001
Inhibition of proteasome activity strongly affects kiwifruit pollen germination. Involvement of the ubiquitin/proteasome pathway as a major regulator.
    Plant physiology, 2001, Volume: 126, Issue:3

    Topics: Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Fruit; Germination; Lactones; Leupeptins; Magnoliopsida; Multienzyme Complexes; Pollen; Proteasome Endopeptidase Complex; Ubiquitins

2001
Proteasome inhibitors block a late step in lysosomal transport of selected membrane but not soluble proteins.
    Molecular biology of the cell, 2001, Volume: 12, Issue:8

    Topics: Animals; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Endocytosis; Humans; Lactones; Leupeptins; Ligands; Lysosomes; Multienzyme Complexes; Nerve Growth Factor; Proteasome Endopeptidase Complex; Protein Transport; Receptor, trkA; Receptors, Somatotropin; Transferrin

2001
The proteasome participates in degradation of mutant alpha 1-antitrypsin Z in the endoplasmic reticulum of hepatoma-derived hepatocytes.
    The Journal of biological chemistry, 2001, Nov-30, Volume: 276, Issue:48

    Topics: Acetylcysteine; alpha 1-Antitrypsin; Animals; Antibiotics, Antineoplastic; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Cysteine Endopeptidases; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Fibroblasts; HeLa Cells; Hepatocytes; Humans; Lactones; Leupeptins; Liver; Mice; Multienzyme Complexes; Mutation; Oligopeptides; Precipitin Tests; Proteasome Endopeptidase Complex; Protein Binding; Rats; Time Factors; Transfection; Tumor Cells, Cultured

2001
Role of proteasomes in the degradation of short-lived proteins in human fibroblasts under various growth conditions.
    The international journal of biochemistry & cell biology, 2003, Volume: 35, Issue:5

    Topics: Autophagy; Cells, Cultured; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Fibroblasts; Humans; Hydrolysis; Kinetics; Lactones; Leupeptins; Lysosomes; Multienzyme Complexes; Proteasome Endopeptidase Complex; Proteins; Scintillation Counting

2003
The C-terminal T peptide of acetylcholinesterase enhances degradation of unassembled active subunits through the ERAD pathway.
    The EMBO journal, 2003, Jul-15, Volume: 22, Issue:14

    Topics: Acetylcholinesterase; Alkaline Phosphatase; Amino Acid Sequence; Amino Acid Substitution; Amino Acids, Aromatic; Animals; Chlorocebus aethiops; Conserved Sequence; COS Cells; Cysteine; Dimerization; Endoplasmic Reticulum; Humans; Lactones; Leupeptins; Molecular Sequence Data; Nippostrongylus; Peptides; Protein Subunits; Rats; Serine

2003
Involvement of the proteasome in activation of endothelial nitric oxide synthase.
    Life sciences, 2003, Sep-12, Volume: 73, Issue:17

    Topics: Animals; Aorta; Blotting, Western; Capillaries; Cattle; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Endothelium, Vascular; Fluoresceins; Lactones; Leupeptins; Mice; Multienzyme Complexes; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Proteasome Endopeptidase Complex

2003
Vif overcomes the innate antiviral activity of APOBEC3G by promoting its degradation in the ubiquitin-proteasome pathway.
    The Journal of biological chemistry, 2004, Feb-27, Volume: 279, Issue:9

    Topics: APOBEC-3G Deaminase; Cell Line; Cell Line, Tumor; Conserved Sequence; Cysteine; Cysteine Endopeptidases; Cytidine Deaminase; Drug Interactions; Enzyme Inhibitors; Gene Deletion; Gene Expression; Gene Products, vif; Half-Life; HIV-1; Humans; Immunosorbent Techniques; Lactones; Leupeptins; Multienzyme Complexes; Mutation; Nucleoside Deaminases; Phosphorylation; Proteasome Endopeptidase Complex; Proteins; Recombinant Proteins; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Structure-Activity Relationship; Transfection; Ubiquitin; vif Gene Products, Human Immunodeficiency Virus

2004
Selective induction of the tumor marker glutathione S-transferase P1 by proteasome inhibitors.
    The Journal of biological chemistry, 2005, Jul-01, Volume: 280, Issue:26

    Topics: Acetylcysteine; Animals; Biomarkers, Tumor; Blotting, Western; Cysteine; DNA-Binding Proteins; DNA, Complementary; Down-Regulation; Enzyme Inhibitors; Epithelial Cells; Genes, Dominant; Glutathione S-Transferase pi; Glutathione Transferase; Intracellular Signaling Peptides and Proteins; Isoenzymes; Kelch-Like ECH-Associated Protein 1; Lactones; Leupeptins; Luciferases; Mice; NF-E2-Related Factor 2; Oligonucleotides, Antisense; Promoter Regions, Genetic; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Isoforms; Protein Structure, Tertiary; Proteins; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering; Time Factors; Trans-Activators; Transfection; Up-Regulation

2005
Proteasome inhibitors eliminate protective effect of postconditioning in cultured neonatal cardiomyocytes.
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2006, Volume: 52, Issue:3

    Topics: Animals; Animals, Newborn; Apoptosis; Cell Hypoxia; Cells, Cultured; Ischemic Preconditioning, Myocardial; Lactones; Leupeptins; Myocytes, Cardiac; Necrosis; Oxygen Consumption; Protease Inhibitors; Proteasome Inhibitors; Rats

2006
Proteasome inhibitor differentially regulates expression of the major immediate early genes of human cytomegalovirus in human central nervous system-derived cell lines.
    Virus research, 2009, Volume: 142, Issue:1-2

    Topics: Activating Transcription Factor 2; Cell Line; Central Nervous System; Cytomegalovirus; Cytomegalovirus Infections; Gene Expression Regulation, Viral; Humans; Immediate-Early Proteins; Lactones; Leupeptins; Oligopeptides; Protease Inhibitors; Proteasome Inhibitors; Proto-Oncogene Proteins c-jun

2009
Ubiquitin proteasomal pathway mediated degradation of p53 in melanoma.
    Archives of biochemistry and biophysics, 2011, Apr-15, Volume: 508, Issue:2

    Topics: Animals; Cell Line, Tumor; Etoposide; G1 Phase; Gene Deletion; Genes, p16; Half-Life; Humans; Lactones; Leupeptins; Melanocytes; Melanoma; Mice; Mice, Transgenic; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Stability; Tumor Suppressor Protein p53; Ubiquitin

2011
Pretreatment with proteasome inhibitors protects against oxidative injuries via PPARα-dependent and -independent pathways in ARPE-19 cells.
    Investigative ophthalmology & visual science, 2012, Aug-31, Volume: 53, Issue:9

    Topics: Aldehydes; Anilides; Cells, Cultured; Cysteine Proteinase Inhibitors; Electrophoretic Mobility Shift Assay; Humans; Lactones; Leupeptins; Oxazoles; Oxidative Stress; PPAR alpha; Retinal Pigment Epithelium; Tyrosine; Vitamin K 3

2012
Two inhibitors of the ubiquitin proteasome system enhance long-term memory formation upon olfactory conditioning in the honeybee (Apis mellifera).
    The Journal of experimental biology, 2014, Oct-01, Volume: 217, Issue:Pt 19

    Topics: Animals; Bees; Conditioning, Classical; Lactones; Leupeptins; Memory, Long-Term; Odorants; Oligopeptides; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Ubiquitin

2014