Compounds > clarithromycin
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clarithromycin and zidovudine

clarithromycin has been researched along with zidovudine in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (41.67)18.2507
2000's5 (20.83)29.6817
2010's9 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, X; Lin, X; Skolnik, S; Wang, J1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Gustavson, L; Kazanjian, P; Vance, E; Watson-Bitar, M1
Sharma, PK; Tami, TA1
Darnowski, JW; Dudley, MN; Rana, KZ; Strayer, AH1
Conville, PS; Craft, C; Davey, RT; Falloon, J; Kovacs, JA; Lane, HC; Masur, H; Metcalf, JA; Petty, B; Piscitelli, SC; Polis, MA; Vogel, S; Walker, RE; Witebsky, FG1
Heald, AE; Pieper, CF; Schiffman, SS1
Aberg, JA; Jacobson, MA; Yajko, DM1
Dhillon, AP; Lee, CA; Mistry, PK; Nitu, IC1
Young, A1
Dousman, L; Freund, YR; Mohagheghpour, N1

Reviews

2 review(s) available for clarithromycin and zidovudine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
AIDS: lessons from the last decade and prospects for the future.
    Ear, nose, & throat journal, 1995, Volume: 74, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Blood Transfusion; Clarithromycin; HIV Seropositivity; Humans; Mycobacterium Infections; Pneumocystis; Pneumonia; Sexual Behavior; Substance-Related Disorders; Trimethoprim; Zidovudine

1995

Trials

2 trial(s) available for clarithromycin and zidovudine

ArticleYear
Pharmacokinetics of clarithromycin and zidovudine in patients with AIDS.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adult; Clarithromycin; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Time Factors; Zidovudine

1995
Eradication of AIDS-related disseminated mycobacterium avium complex infection after 12 months of antimycobacterial therapy combined with highly active antiretroviral therapy.
    The Journal of infectious diseases, 1998, Volume: 178, Issue:5

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Anti-HIV Agents; Clarithromycin; Drug Therapy, Combination; Ethambutol; Female; Humans; Lamivudine; Male; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Rifabutin; Stavudine; Zidovudine

1998

Other Studies

20 other study(ies) available for clarithromycin and zidovudine

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Clarithromycin does not affect phosphorylation of zidovudine in vitro.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:8

    Topics: Anti-Bacterial Agents; Anti-HIV Agents; CD4-Positive T-Lymphocytes; Clarithromycin; Humans; Phosphorylation; Tumor Cells, Cultured; Zidovudine

1996
Clarithromycin lowers plasma zidovudine levels in persons with human immunodeficiency virus infection.
    Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:8

    Topics: Adult; Anti-Bacterial Agents; Anti-HIV Agents; Clarithromycin; Drug Interactions; HIV Infections; Humans; Male; Middle Aged; Time Factors; Zidovudine

1997
Taste and smell complaints in HIV-infected patients.
    AIDS (London, England), 1998, Sep-10, Volume: 12, Issue:13

    Topics: Adult; Aged; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Clarithromycin; Didanosine; Female; HIV Infections; Humans; Indinavir; Lamivudine; Male; Middle Aged; Quality of Life; Ritonavir; Smell; Surveys and Questionnaires; Taste; Trimethoprim, Sulfamethoxazole Drug Combination; Zidovudine

1998
Management of liver failure in a haemophilic patient co-infected with human immunodeficiency and hepatitis C viruses.
    Clinical and laboratory haematology, 1999, Volume: 21, Issue:2

    Topics: Anti-Bacterial Agents; Anti-HIV Agents; Clarithromycin; Didanosine; Hemophilia A; Hepacivirus; Hepatitis C; HIV Infections; Humans; Liver Failure, Acute; Male; Middle Aged; Zidovudine

1999
Hold the big MAC.
    Notes from the underground (New York, N.Y.), 1996, Issue:no 32

    Topics: AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Antibiotic Prophylaxis; Antibiotics, Antitubercular; Clarithromycin; Humans; Mycobacterium avium-intracellulare Infection; Rifabutin; Zidovudine

1996
Pot shots.
    Notes from the underground (New York, N.Y.), 1996, Issue:No 33

    Topics: Acetylcysteine; AIDS-Related Opportunistic Infections; Animals; Anti-Bacterial Agents; Antitubercular Agents; Antiviral Agents; Cattle; CD4 Lymphocyte Count; China; Clarithromycin; Clinical Trials as Topic; Clofazimine; Cryptosporidiosis; Drug Combinations; Ethambutol; Expectorants; Glutathione; Hepatitis B; Humans; Immunoglobulins; Interferon-alpha; Italy; Leprostatic Agents; Mycobacterium avium-intracellulare Infection; Philippines; Protease Inhibitors; Survival Rate; Taiwan; Thymosin; Zidovudine

1996
MAC management.
    PI perspective, 1996, Issue:No 20

    Topics: Acquired Immunodeficiency Syndrome; Amikacin; Antitubercular Agents; Ciprofloxacin; Clarithromycin; Clofazimine; Drug Interactions; Drug Therapy, Combination; Ethambutol; Humans; Mycobacterium avium-intracellulare Infection; Rifabutin; Rifampin; Tuberculin Test; Zidovudine

1996
Prophylactic clarithromycin to treat mycobacterium avium in HIV patients receiving zidovudine may significantly increase mortality by suppressing lymphopoiesis and hematopoiesis.
    International immunopharmacology, 2002, Volume: 2, Issue:10

    Topics: AIDS-Related Opportunistic Infections; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Cell Line; Clarithromycin; Dose-Response Relationship, Drug; Female; Hematopoiesis; HIV Infections; Humans; Lymphocyte Activation; Lymphopoiesis; Mice; Mice, Inbred BALB C; Mycobacterium avium-intracellulare Infection; Zidovudine

2002