Page last updated: 2024-08-25

clarithromycin and troleandomycin

clarithromycin has been researched along with troleandomycin in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's3 (23.08)18.2507
2000's3 (23.08)29.6817
2010's5 (38.46)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Casciano, CN; Clement, RP; Johnson, WW; Wang, EJ1
Dansette, PM; Fontana, E; Poli, SM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Descatoire, V; Labbe, G; Larrey, D; Letteron, P; Loeper, J; Pessayre, D; Tinel, M1
Oster, G; Thompson, D1
Flurer, CL1
Counihan, M; Duan, SX; Durol, AL; Graf, JA; Greenblatt, DJ; Harmatz, JS; Mertzanis, P; Shader, RI; von Moltke, LL; Wright, CE1
Kim, SG; Kim, SH; Kim, WB; Kwon, JW; Lee, AK; Lee, JH; Lee, MG1
Albaugh, DR; Fisher, MB; Fullenwider, CL; Hutzler, JM1
Abraham, TL; Bedwell, DW; Hall, SD; Hansen, K; Rougée, LRA1

Reviews

1 review(s) available for clarithromycin and troleandomycin

ArticleYear
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
    Current drug metabolism, 2005, Volume: 6, Issue:5

    Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic

2005

Trials

1 trial(s) available for clarithromycin and troleandomycin

ArticleYear
Inhibition of triazolam clearance by macrolide antimicrobial agents: in vitro correlates and dynamic consequences.
    Clinical pharmacology and therapeutics, 1998, Volume: 64, Issue:3

    Topics: Administration, Oral; Anti-Bacterial Agents; Aryl Hydrocarbon Hydroxylases; Azithromycin; Clarithromycin; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Double-Blind Method; Erythromycin; Humans; Hypnotics and Sedatives; In Vitro Techniques; Microsomes, Liver; Oxidoreductases, N-Demethylating; Time Factors; Triazolam; Troleandomycin

1998

Other Studies

11 other study(ies) available for clarithromycin and troleandomycin

ArticleYear
Active transport of fluorescent P-glycoprotein substrates: evaluation as markers and interaction with inhibitors.
    Biochemical and biophysical research communications, 2001, Nov-30, Volume: 289, Issue:2

    Topics: 3T3 Cells; Adrenergic Uptake Inhibitors; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Biological Transport, Active; Cell Line; Cell Separation; Cell Survival; Flow Cytometry; Fluorescent Dyes; Humans; Inhibitory Concentration 50; Mice; Protein Binding; Reserpine; Spectrometry, Fluorescence; Substrate Specificity; Time Factors

2001
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Effects of clarithromycin on cytochrome P-450. Comparison with other macrolides.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:2

    Topics: Animals; Clarithromycin; Cytochrome P-450 Enzyme System; Dealkylation; Dexamethasone; Enzyme Induction; Erythromycin; Iron; Isoenzymes; Male; Rats; Rats, Inbred Strains; Troleandomycin

1989
Use of terfenadine and contraindicated drugs.
    JAMA, 1996, May-01, Volume: 275, Issue:17

    Topics: Anti-Bacterial Agents; Antifungal Agents; Clarithromycin; Contraindications; Drug Interactions; Drug Utilization; Erythromycin; Histamine H1 Antagonists; Humans; Itraconazole; Ketoconazole; Pharmaceutical Services; Product Labeling; Retrospective Studies; Terfenadine; Troleandomycin

1996
Analysis of macrolide antibiotics by capillary electrophoresis.
    Electrophoresis, 1996, Volume: 17, Issue:2

    Topics: Acetonitriles; Anti-Bacterial Agents; Buffers; Carbohydrate Sequence; Cholic Acid; Cholic Acids; Clarithromycin; Electrophoresis, Capillary; Erythromycin; Molecular Sequence Data; Molecular Structure; Oleandomycin; Spiramycin; Troleandomycin

1996
Pharmacokinetics of clarithromycin in rats with acute renal failure induced by uranyl nitrate.
    Biopharmaceutics & drug disposition, 2004, Volume: 25, Issue:6

    Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Clarithromycin; Cytochrome P-450 CYP3A; Dexamethasone; Enzyme Induction; Half-Life; Injections, Intravenous; Isoenzymes; Male; Membrane Proteins; Rats; Rats, Sprague-Dawley; Time Factors; Troleandomycin; Uranyl Nitrate

2004
Time-dependent inhibition and estimation of CYP3A clinical pharmacokinetic drug-drug interactions using plated human cell systems.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:7

    Topics: Cells, Cultured; Clarithromycin; Cryopreservation; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Hepatocytes; Humans; Kinetics; Microsomes, Liver; Troleandomycin; Verapamil

2012
Impact of Heterotropic Allosteric Modulation on the Time-Dependent Inhibition of Cytochrome P450 3A4.
    Drug metabolism and disposition: the biological fate of chemicals, 2023, Volume: 51, Issue:10

    Topics: Carbamazepine; Clarithromycin; Cytochrome P-450 CYP3A; Drug Interactions; Humans; Microsomes, Liver; Midazolam; Troleandomycin

2023