Page last updated: 2024-08-25

clarithromycin and trimethoprim

clarithromycin has been researched along with trimethoprim in 30 studies

Research

Studies (30)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (3.33)	18.7374
1990's	3 (10.00)	18.2507
2000's	12 (40.00)	29.6817
2010's	11 (36.67)	24.3611
2020's	3 (10.00)	2.80

Authors

Authors	Studies
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA	1
Keserü, GM	1
Cho, SH; Franzblau, SG; Hwang, CH; Pauli, GF; Wan, B; Warit, S	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Campbell, BJ; Edwards, SW; Hart, CA; Martin, HM; Rhodes, JM; Roberts, CL; Subramanian, S	1
Lombardo, F; Obach, RS; Waters, NJ	1
Jia, L; Sun, H	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, X; Lin, X; Skolnik, S; Wang, J	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Ashenden, S; Bender, A; Cokol, M; Karakoc, I; Kuru, N; Mason, DJ; Meral, S; Stott, I; Weinstein, ZB	1
Kapell, KS; Kessler, HA; Segreti, J; Trenholme, GM	1
Sharma, PK; Tami, TA	1
Hughes, WT; Killmar, JT; Oz, HS	1
Hirsh, DC; Jang, SS	1
Asencio Marchante, R; Lissen Otero, E	1
Carriere, KC; Jin, Y; Johnson, D; Marrie, T	1
Giger, W; Göbel, A; Joss, A; McArdell, CS; Thomsen, A	1
Gagnon, C; García-Ac, A; Ghosh, D; Lajeunesse, A; Sauvé, S; Segura, PA	1
Andersen, JT; Broedbaek, K; Cejvanovic, V; Hansen, LK; Henriksen, T; Jimenez-Solem, E; Kjaer, LK; Larsen, EL; Lykkesfeldt, J; Pedersen, MT; Petersen, M; Popik, SD; Poulsen, HE; Torp-Pedersen, C; Weimann, A	1
Álvarez-Rodríguez, E; Arias-Estévez, M; Cela-Dablanca, R; Fernández-Calviño, D; Núñez-Delgado, A; Rodríguez-López, L	1
Aleer, SC; Donner, E; Drigo, B; Fatta-Kassinos, D; Jäger, T; Michael, C; Michael, SG; Michael-Kordatou, I; Schwartz, T	1
Álvarez-Rodríguez, E; Arias-Estévez, M; Díaz-Raviña, M; Fernández-Calviño, D; Núñez-Delgado, A; Rodríguez-González, L; Santás-Miguel, V	1

Reviews

2 review(s) available for clarithromycin and trimethoprim

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
AIDS: lessons from the last decade and prospects for the future. Ear, nose, & throat journal, 1995, Volume: 74, Issue:5 Topics: Acquired Immunodeficiency Syndrome; Blood Transfusion; Clarithromycin; HIV Seropositivity; Humans; Mycobacterium Infections; Pneumocystis; Pneumonia; Sexual Behavior; Substance-Related Disorders; Trimethoprim; Zidovudine	1995

Trials

1 trial(s) available for clarithromycin and trimethoprim

Article	Year
Clarithromycin, trimethoprim, and penicillin and oxidative nucleic acid modifications in humans: randomised, controlled trials. British journal of clinical pharmacology, 2017, Volume: 83, Issue:8 Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Anti-Bacterial Agents; Biomarkers; Clarithromycin; Deoxyguanosine; DNA; Guanosine; Healthy Volunteers; Humans; Lipid Peroxidation; Male; Malondialdehyde; Oxidation-Reduction; Oxidative Stress; Penicillin V; Placebos; Reactive Oxygen Species; RNA; Trimethoprim; Young Adult	2017

Article

Year

Clarithromycin, trimethoprim, and penicillin and oxidative nucleic acid modifications in humans: randomised, controlled trials.

British journal of clinical pharmacology, 2017, Volume: 83, Issue:8

Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Anti-Bacterial Agents; Biomarkers; Clarithromycin; Deoxyguanosine; DNA; Guanosine; Healthy Volunteers; Humans; Lipid Peroxidation; Male; Malondialdehyde; Oxidation-Reduction; Oxidative Stress; Penicillin V; Placebos; Reactive Oxygen Species; RNA; Trimethoprim; Young Adult

2017

Other Studies

27 other study(ies) available for clarithromycin and trimethoprim

Article	Year
Rational use of in vitro P-glycoprotein assays in drug discovery. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera	2001
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship	2003
Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4 Topics: Anti-Bacterial Agents; Antitubercular Agents; DNA, Bacterial; Drug Evaluation, Preclinical; Mycobacterium tuberculosis; Oxygen	2007
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:2 Topics: Animals; Anti-Bacterial Agents; Cell Line; Cells, Cultured; Colon; Crohn Disease; Culture Media; Escherichia coli; Humans; Macrophages; Mice; Microbial Sensitivity Tests; Monocytes; Mucous Membrane	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Support vector machines classification of hERG liabilities based on atom types. Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11 Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2 Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Prediction of Antibiotic Interactions Using Descriptors Derived from Molecular Structure. Journal of medicinal chemistry, 2017, 05-11, Volume: 60, Issue:9 Topics: Anti-Bacterial Agents; Drug Interactions; Molecular Structure	2017
In vitro activity of A-56268 (TE-031) and four other antimicrobial agents against Chlamydia trachomatis. Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:1 Topics: Anti-Bacterial Agents; Chlamydia trachomatis; Ciprofloxacin; Clarithromycin; Doxycycline; Drug Combinations; Erythromycin; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination	1987
Relative potency of 10 drugs with anti-Pneumocystis carinii activity in an animal model. The Journal of infectious diseases, 1994, Volume: 170, Issue:4 Topics: Animals; Anti-Infective Agents; Atovaquone; Azithromycin; Clarithromycin; Clindamycin; Clinical Trials as Topic; Dapsone; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Humans; Naphthoquinones; Pentamidine; Pneumocystis Infections; Proguanil; Pyrimethamine; Rats; Sulfadoxine; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination	1994
Antimicrobial susceptibility of Nocardia nova isolated from five cats with nocardiosis. Journal of the American Veterinary Medical Association, 1999, Sep-15, Volume: 215, Issue:6 Topics: Animals; Anti-Bacterial Agents; Cat Diseases; Cats; Clarithromycin; Drug Combinations; Male; Microbial Sensitivity Tests; Nocardia; Nocardia Infections; Sulfonamides; Treatment Outcome; Trimethoprim	1999
[Secondary prevention of opportunistic infections in HIV-infected patients]. Revista clinica espanola, 2001, Volume: 201, Issue:2 Topics: AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Anti-Infective Agents; Antiprotozoal Agents; Antitubercular Agents; Antiviral Agents; Clarithromycin; Cytomegalovirus Infections; Drug Therapy, Combination; Ethambutol; Ganciclovir; Humans; Leucovorin; Mycobacterium avium-intracellulare Infection; Pneumonia, Pneumocystis; Pyrimethamine; Recurrence; Rifabutin; Sulfadiazine; Sulfamethoxazole; Toxoplasmosis; Trimethoprim	2001
Appropriate antibiotic utilization in seniors prior to hospitalization for community-acquired pneumonia is associated with decreased in-hospital mortality. Journal of clinical pharmacy and therapeutics, 2004, Volume: 29, Issue:3 Topics: Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Clarithromycin; Community-Acquired Infections; Comorbidity; Drug Prescriptions; Drug Utilization; Female; Hospital Mortality; Hospitalization; Humans; Male; Odds Ratio; Pneumonia; Preventive Health Services; Retrospective Studies; Sulfamethoxazole; Survival Rate; Trimethoprim	2004
Occurrence and sorption behavior of sulfonamides, macrolides, and trimethoprim in activated sludge treatment. Environmental science & technology, 2005, Jun-01, Volume: 39, Issue:11 Topics: Adsorption; Anti-Infective Agents; Azithromycin; Clarithromycin; Environmental Monitoring; Humans; Macrolides; Sewage; Sulfamethoxazole; Sulfonamides; Trimethoprim; Waste Disposal, Fluid; Water Pollutants, Chemical	2005
Determination of six anti-infectives in wastewater using tandem solid-phase extraction and liquid chromatography-tandem mass spectrometry. Journal of environmental monitoring : JEM, 2007, Volume: 9, Issue:4 Topics: Anti-Infective Agents; Azithromycin; Chromatography, Liquid; Ciprofloxacin; Clarithromycin; Ofloxacin; Sewage; Solid Phase Extraction; Sulfamethoxazole; Tandem Mass Spectrometry; Trimethoprim; Water Pollutants, Chemical	2007
Photodegradation of Ciprofloxacin, Clarithromycin and Trimethoprim: Influence of pH and Humic Acids. Molecules (Basel, Switzerland), 2021, May-21, Volume: 26, Issue:11 Topics: Anti-Bacterial Agents; Ciprofloxacin; Clarithromycin; Darkness; Half-Life; Humic Substances; Hydrogen-Ion Concentration; Kinetics; Light; Trimethoprim	2021
The effect of ultrafiltration process on the fate of antibiotic-related microcontaminants, pathogenic microbes, and toxicity in urban wastewater. Journal of hazardous materials, 2022, 08-05, Volume: 435 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Bacterial Agents; Bacteria; Clarithromycin; Trimethoprim; Ultrafiltration; Wastewater	2022
Direct toxicity of six antibiotics on soil bacterial communities affected by the addition of bio-adsorbents. Environmental pollution (Barking, Essex : 1987), 2023, Apr-01, Volume: 322 Topics: Amoxicillin; Anti-Bacterial Agents; Azithromycin; Biomass; Ciprofloxacin; Clarithromycin; Soil; Soil Pollutants; Trimethoprim	2023