Page last updated: 2024-08-25

clarithromycin and theophylline

clarithromycin has been researched along with theophylline in 19 studies

Research

Studies (19)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	4 (21.05)	18.2507
2000's	6 (31.58)	29.6817
2010's	9 (47.37)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Kobayashi, Y; Kohyama, N; Ohbayashi, M; Ohshiro, N; Sakai, R; Yamamoto, T	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Climo, MW; Gillum, JG; Israel, DS; Polk, RE; Scott, RB	1
Adachi, T; Fukuda, T; Hirata, A; Kihara, N; Kosaku, A; Makino, S; Motojima, S; Ohtake, H	1
de'Clari, F	1
Ebihara, I; Koide, H; Omuro, H; Saka, S; Shimada, N	1
Bruce, MA; Gorski, JC; Haehner-Daniels, BD; Hall, SD	1
Enomoto, H; Hasegawa, A; Kawana, H; Kitada, M; Kuriyama, T; Nakamura, H; Ohmori, S; Ohtsuka, T	1
Alder, J; Brown, HS; Houston, JB; Wilby, AJ	1

Reviews

1 review(s) available for clarithromycin and theophylline

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

2 trial(s) available for clarithromycin and theophylline

Article	Year
Effect of combination therapy with ciprofloxacin and clarithromycin on theophylline pharmacokinetics in healthy volunteers. Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:7 Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Clarithromycin; Cross-Over Studies; Drug Interactions; Drug Therapy, Combination; Humans; Male; Theophylline	1996
In vivo effect of clarithromycin on multiple cytochrome P450s. Drug metabolism and disposition: the biological fate of chemicals, 2001, Volume: 29, Issue:7 Topics: Adult; Anti-Bacterial Agents; Area Under Curve; Caffeine; Chromatography, High Pressure Liquid; Clarithromycin; Cross-Over Studies; Cytochrome P-450 Enzyme System; Female; Humans; Male; Theophylline; Tolbutamide	2001

Other Studies

16 other study(ies) available for clarithromycin and theophylline

Article	Year
Possible involvement of organic anion transporter 2 on the interaction of theophylline with erythromycin in the human liver. Drug metabolism and disposition: the biological fate of chemicals, 2005, Volume: 33, Issue:5 Topics: Animals; Anti-Bacterial Agents; Blood Proteins; Drug Interactions; Erythromycin; Humans; Kinetics; Liver; Oocytes; Organic Anion Transporters, Sodium-Independent; Phosphodiesterase Inhibitors; Protein Binding; RNA, Complementary; Theophylline; Xenopus laevis	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Eosinophil apoptosis caused by theophylline, glucocorticoids, and macrolides after stimulation with IL-5. The Journal of allergy and clinical immunology, 1996, Volume: 98, Issue:6 Pt 2 Topics: Aminophylline; Animals; Apoptosis; Cell Survival; Cells, Cultured; Clarithromycin; Drug Antagonism; Eosinophils; Erythromycin; Glucocorticoids; Guinea Pigs; Humans; Interleukin-5; Macrolides; Methylprednisolone; Peritoneal Lavage; Theophylline	1996
Ciprofloxacin was the culprit--not itraconazole. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1997, Volume: 24, Issue:1 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Bronchodilator Agents; Central Nervous System; Ciprofloxacin; Clarithromycin; Drug Interactions; Drug Therapy, Combination; Humans; Itraconazole; Theophylline; Time Factors	1997
[A case of acute renal failure with rhabdomyolysis caused by the interaction of theophylline and clarithromycin]. Nihon Jinzo Gakkai shi, 1999, Volume: 41, Issue:4 Topics: Acute Kidney Injury; Aged; Anti-Bacterial Agents; Bronchodilator Agents; Clarithromycin; Cytochrome P-450 Enzyme Inhibitors; Delayed-Action Preparations; Drug Interactions; Drug Therapy, Combination; Humans; Liver; Male; Rhabdomyolysis; Theophylline	1999
Effect of levofloxacin on theophylline clearance during theophylline and clarithromycin combination therapy. The Annals of pharmacotherapy, 2001, Volume: 35, Issue:6 Topics: Anti-Infective Agents; Clarithromycin; Drug Interactions; Drug Therapy, Combination; Emphysema; Humans; Levofloxacin; Male; Metabolic Clearance Rate; Middle Aged; Ofloxacin; Theophylline	2001
Comparative use of isolated hepatocytes and hepatic microsomes for cytochrome P450 inhibition studies: transporter-enzyme interplay. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Animals; Cell Separation; Clarithromycin; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Enoxacin; Enzyme Inhibitors; Hepatocytes; Male; Microsomes, Liver; Midazolam; Nelfinavir; Rats; Rats, Sprague-Dawley; Saquinavir; Theophylline	2010