Page last updated: 2024-08-25

clarithromycin and ru 66647

clarithromycin has been researched along with ru 66647 in 68 studies

Research

Studies (68)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (7.35)	18.2507
2000's	48 (70.59)	29.6817
2010's	14 (20.59)	24.3611
2020's	1 (1.47)	2.80

Authors

Authors	Studies
Appelbaum, PC; Ednie, LM; Jacobs, MR	1
Bryskier, A; Hoppe, JE	1
Citron, DM; Goldstein, EJ; Hudspeth, M; Hunt Gerardo, S; Merriam, CV	1
Appelbaum, PC; Credito, KL; Ednie, LM; Jacobs, MR	1
Citron, DM; Goldstein, EJ; Merriam, CV; Tyrrell, K; Warren, Y	1
Douthwaite, S; Hansen, LH; Mauvais, P	1
Berchel, M; Bryskier, A; Goh, KS; Rastogi, N	1
Alván, G; Barkholt, L; Edlund, C; Nord, CE; Vacheron, F	1
Barry, AL; Brown, SD; Fuchs, PC	1
Appelbaum, PC; Bryskier, A; Davies, TA; Ednie, LM; Jacobs, MR; Nagai, K; Palavecino, E	1
Bryskier, A; Lascols, C; Soussy, CJ; Tanković, J	1
Chuah, SK; Gollapudi, S; Iskandar, L; Thadepalli, H	1
Ahrén, IL; Forsgren, A; Karlsson, E; Riesbeck, K	1
Cardus, S; Démolis, JL; Funck-Brentano, C; Vacheron, F	1
Quinn, J; Ruoff, GE; Ziter, PS	1
Carbon, C; Dunbar, L; Fogarty, C; Hagberg, L; Pullman, J; van Rensburg, DJ	1
Amyes, S; Walsh, F; Willcock, J	1
Chronopoulou, G; Foustoukou, M; Ioannidou, S; Kanavaki, S; Kanelopoulou, M; Pangalis, A; Papafraggas, E; Petropoulou, N; Salem, Z; Tassios, PT; Trikka-Graphakos, E; Vatopoulos, AC; Zachariadou, L	1
Arnheim, K	1
Chang, J; Cots, JM; Domínguez-Gil, A; Herreras, A; Rubio-Terrés, C; Sánchez Gascón, F; Trilla, A	1
Hassman, J; Mathers Dunbar, L; Tellier, G	1
Asche, CV; Chang, JR; Lavin, B; Stewart, J; Sullivan, SD; Tellier, G	1
Chang, JR; Niederman, MS; Nieman, RB; Nusrat, R; Stewart, J	1
Leroy, B; Norrby, SR; Quinn, J; Rangaraju, M	1
Colombo, A; De Vecchi, E; Drago, L; Gismondo, MR; Nicola, L	1
Asche, CV; Chang, JR; Lavin, B; Niederman, MS; Nusrat, R; Stewart, J; Sullivan, SD	1
Lavin, B; Niederman, MS; Nusrat, R; Patel, M; Tellier, G	1
Zuckerman, JM	1
Appelbaum, PC; Bozdogan, B; Clark, CL; Credito, KL; Ednie, LM; Jacobs, MR; Kelly, LM; Kosowska, K; Lin, G; Matic, V; McGhee, P; Pankuch, GA; Smith, K	1
Appelbaum, PC; Clark, C; Credito, K; Dewasse, B; Hoellman, D; Jacobs, MR; Kosowska, K; Lin, G; McGhee, P; Pankuch, GA	1
Barrett, JS; Bhargava, VO; Chapel, S; Hardy, P; Leroy, B; Montay, G; Noveck, R; Shi, J; Sica, D; Swan, SK	1
Böttger, EC; Bruell, C; Corti, N; Hobbie, S; Pfister, P; Yonath, A; Zarivach, R	1
Bosnar, M; Eraković, V; Kelnerić, Z; Munić, V; Parnham, MJ	1
Bolla, JM; Mamelli, L; Mégraud, F; Pagès, JM; Prouzet-Mauléon, V	1
Alferova, IV; Firsov, AA; Lubenko, IY; Portnoy, YA; Vostrov, SN; Zinner, SH	1
Chang, J; de Wet, R; Fogarty, C; Mandell, L; Nusrat, R; Rangaraju, M	1
Drugeon, H; Filipecki, J; Goldfarb, G; Léophonte, P; Perronne, C; Vincent-Lacaze, N; Zuck, P	1
De Vecchi, E; Drago, L; Gismondo, MR; Legnani, D; Nicola, L	1
Appelbaum, PC; Bogdanovich, T; Bozdogan, B	1
Ellis, MC; Ellis, MW; Griffith, ME; Hawley, JS; Hospenthal, DR; McCall, S; Moon, JE; Murray, CK; Rivard, RG	1
Higashiyama, Y; Higuchi, N; Hirakata, Y; Kadota, J; Kohno, S; Kuroki, M; Miyazaki, Y; Mizuta, Y; Mukae, H; Ohno, H; Tomono, K; Tsukamoto, K; Yanagihara, K	1
Busman, TA; Gotfried, M; Norris, S; Notario, GF	1
Appelbaum, PC; Clark, CL; Ednie, LM; Kosowska-Shick, K	1
Chan, FK; Lee, CC; Lee, VW; Ling, TK	1
Izumikawa, K; Kakeya, H; Kamihira, S; Kohno, S; Morinaga, Y; Nakamura, S; Seki, M; Yamada, Y; Yamamoto, Y; Yanagihara, K	1
De Vecchi, E; Drago, L; Larosa, M; Nicola, L	1
Ando, S; Inoue, M; Kishimoto, T; Ogawa, M; Sato, K; Takemura, H; Yamazaki, T	1
Amenomori, M; Fujita, H; Imamura, Y; Ishii, H; Ishimoto, H; Kitazaki, T; Kohno, S; Mukae, H; Nakayama, S; Sakamoto, N; Yanagihara, K	1
Aolie, J; El-Khatib, WF; Noreddin, AM; Salem, AH; Zhanel, GG	1
Chen, XZ; Jin, ZP; Lei, PS; Li, Y; Liu, J; Liu, L; Wang, GQ; Xu, P	1
Izumikawa, K; Kakeya, H; Kamihira, S; Kohno, S; Miyashita, N; Morinaga, Y; Mukae, H; Seki, M; Yamada, Y; Yamamoto, Y; Yanagihara, K	1
Chono, S; Morimoto, K; Seki, T; Togami, K	1
Bono, BR; Qamar, F; Zuckerman, JM	1
Liu, CN; Somps, CJ	1
Castanheira, M; Jones, RN; Woosley, LN	1
Tang, D; Ying, L	1
Giguère, S; Javsicas, LH; Womble, AY	1
Ishii, Y; Kimura, S; Sato, T; Tateda, K; Yamaguchi, K	1
Ihara, T; Sugamata, M; Takeda, K; Tanaka, N; Umezawa, M	1
Fujita, H; Hara, A; Hara, S; Ishimatsu, Y; Kakugawa, T; Kohno, S; Mukae, H; Sakamoto, N	1
Bencetić Mihaljević, V; Letfus, V; Milić, A; Padovan, J; Ralić, J	1
Bhateja, P; Chakrabarti, A; Das, B; Dullu, J; Hajare, AK; Jadhav, JS; Kumar, R; Pandya, M; Ramkumar, G; Rathy, S; Surase, YB; Venkataramanan, R	1
Chono, S; Morimoto, K; Togami, K	1
Jin, YH; Li, XM; Wang, FC; Yang, F	1
Derendorf, H; Ikawa, K; Kikuchi, E; Kikuchi, J; Morikawa, N; Nishimura, M	1
Chono, S; Hayashi, Y; Morimoto, K; Togami, K	1
Hofmann, T; Scheuch, G; Siekmeier, R	1
Pejčić, AV	1

Reviews

7 review(s) available for clarithromycin and ru 66647

Article	Year
Telithromycin in the treatment of community-acquired pneumonia: a pooled analysis. Respiratory medicine, 2003, Volume: 97, Issue:6 Topics: Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Clarithromycin; Clinical Trials, Phase III as Topic; Community-Acquired Infections; Double-Blind Method; Fluoroquinolones; Humans; Ketolides; Macrolides; Naphthyridines; Penicillins; Pneumonia, Bacterial; Randomized Controlled Trials as Topic; Treatment Outcome	2003
Macrolides and ketolides: azithromycin, clarithromycin, telithromycin. Infectious disease clinics of North America, 2004, Volume: 18, Issue:3 Topics: Anti-Bacterial Agents; Azithromycin; Bacterial Infections; Clarithromycin; Humans; Ketolides; Macrolides	2004
Macrolides, ketolides, and glycylcyclines: azithromycin, clarithromycin, telithromycin, tigecycline. Infectious disease clinics of North America, 2009, Volume: 23, Issue:4 Topics: Anti-Bacterial Agents; Azithromycin; Bacterial Infections; Clarithromycin; Humans; Ketolides; Macrolides; Minocycline; Tetracyclines; Tigecycline	2009
Recent advances in the medicinal chemistry of novel erythromycin-derivatized antibiotics. Current topics in medicinal chemistry, 2010, Volume: 10, Issue:14 Topics: Anti-Bacterial Agents; Azithromycin; Chemistry, Pharmaceutical; Clarithromycin; Drug Resistance, Microbial; Erythromycin; Humans; Ketolides; Macrolides	2010
Telithromycin versus clarithromycin for the treatment of community-acquired respiratory tract infections: a meta-analysis of randomized controlled trials. Chinese medical journal, 2013, Volume: 126, Issue:11 Topics: Anti-Bacterial Agents; Clarithromycin; Community-Acquired Infections; Humans; Ketolides; Randomized Controlled Trials as Topic; Respiratory Tract Infections	2013
Inhalation of macrolides: a novel approach to treatment of pulmonary infections. Advances in experimental medicine and biology, 2015, Volume: 839 Topics: Administration, Inhalation; Aerosols; Animals; Anti-Bacterial Agents; Azithromycin; Bronchiectasis; Clarithromycin; Cystic Fibrosis; Erythromycin; Humans; Ketolides; Lung; Macrolides; Pulmonary Disease, Chronic Obstructive; Rats	2015
Stevens-Johnson syndrome and toxic epidermal necrolysis associated with the use of macrolide antibiotics: a review of published cases. International journal of dermatology, 2021, Volume: 60, Issue:1 Topics: Anti-Bacterial Agents; Azithromycin; Clarithromycin; Erythromycin; Humans; Ketolides; Macrolides; Roxithromycin; Stevens-Johnson Syndrome	2021

Trials

13 trial(s) available for clarithromycin and ru 66647

Article	Year
Pharmacokinetics and comparative effects of telithromycin (HMR 3647) and clarithromycin on the oropharyngeal and intestinal microflora. The Journal of antimicrobial chemotherapy, 2000, Volume: 46, Issue:5 Topics: Administration, Oral; Adolescent; Adult; Anti-Bacterial Agents; Area Under Curve; Bacteroides; Clarithromycin; Double-Blind Method; Feces; Female; Humans; Intestines; Ketolides; Macrolides; Male; Microbial Sensitivity Tests; Oropharynx; Respiratory Tract Infections; Saliva; Statistics, Nonparametric	2000
Effect of single and repeated oral doses of telithromycin on cardiac QT interval in healthy subjects. Clinical pharmacology and therapeutics, 2003, Volume: 73, Issue:3 Topics: Administration, Oral; Adult; Analysis of Variance; Anti-Bacterial Agents; Clarithromycin; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Electrocardiography; Exercise Test; Female; Heart Conduction System; Humans; Ketolides; Macrolides; Male; Reference Values; Rest	2003
Efficacy and tolerability of 5-day, once-daily telithromycin compared with 10-day, twice-daily clarithromycin for the treatment of group A beta-hemolytic streptococcal tonsillitis/pharyngitis: a multicenter, randomized, double-blind, parallel-group study. Clinical therapeutics, 2003, Volume: 25, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Clarithromycin; Double-Blind Method; Drug Administration Schedule; Drug Resistance, Bacterial; Erythromycin; Female; Humans; Ketolides; Macrolides; Male; Middle Aged; Streptococcal Infections; Streptococcus pyogenes; Tonsillitis; Treatment Outcome	2003
Efficacy and tolerability of once-daily oral telithromycin compared with clarithromycin for the treatment of community-acquired pneumonia in adults. Clinical therapeutics, 2004, Volume: 26, Issue:1 Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Clarithromycin; Community-Acquired Infections; Double-Blind Method; Drug Resistance, Bacterial; Female; Humans; Ketolides; Macrolides; Male; Middle Aged; Pneumonia	2004
Comparison of hospitalization rates in patients with community-acquired pneumonia treated with telithromycin for 5 or 7 days or clarithromycin for 10 days. Current medical research and opinion, 2004, Volume: 20, Issue:5 Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Clarithromycin; Community-Acquired Infections; Double-Blind Method; Female; Hospitalization; Humans; Ketolides; Macrolides; Male; Middle Aged; Pneumonia; Treatment Outcome	2004
Comparison of hospitalization rates in patients with community-acquired pneumonia treated with 10 days of telithromycin or clarithromycin. Current medical research and opinion, 2004, Volume: 20, Issue:5 Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Anti-Bacterial Agents; Clarithromycin; Community-Acquired Infections; Double-Blind Method; Female; Hospitalization; Humans; Ketolides; Macrolides; Male; Middle Aged; Pneumonia; Treatment Outcome	2004
Evaluation of 5-day therapy with telithromycin, a novel ketolide antibacterial, for the treatment of tonsillopharyngitis. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2004, Volume: 10, Issue:7 Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Child; Child, Preschool; Clarithromycin; Female; Humans; Infant; Ketolides; Macrolides; Male; Microbial Sensitivity Tests; Middle Aged; Penicillin V; Pharyngitis; Streptococcal Infections; Streptococcus pyogenes; Tonsillitis; Treatment Outcome	2004
Hospitalization rates among patients with community-acquired pneumonia treated with telithromycin vs clarithromycin: results from two randomized, double-blind, clinical trials. Current medical research and opinion, 2004, Volume: 20, Issue:7 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Clarithromycin; Community-Acquired Infections; Double-Blind Method; Female; Hospitalization; Humans; Ketolides; Macrolides; Male; Middle Aged; Pneumonia, Bacterial	2004
Clinical and bacteriological efficacy and safety of 5 and 7 day regimens of telithromycin once daily compared with a 10 day regimen of clarithromycin twice daily in patients with mild to moderate community-acquired pneumonia. The Journal of antimicrobial chemotherapy, 2004, Volume: 54, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Clarithromycin; Community-Acquired Infections; Double-Blind Method; Drug Resistance, Bacterial; Electrocardiography; Enzyme Induction; Female; Haemophilus influenzae; Humans; Ketolides; Liver Function Tests; Macrolides; Male; Middle Aged; Moraxella catarrhalis; Pneumonia; Sample Size; Sputum; Streptococcus pneumoniae; Treatment Outcome	2004
Effect of ketoconazole on the pharmacokinetics and safety of telithromycin and clarithromycin in older subjects with renal impairment. International journal of clinical pharmacology and therapeutics, 2005, Volume: 43, Issue:3 Topics: Aged; Anti-Bacterial Agents; Antifungal Agents; Area Under Curve; Biological Availability; Clarithromycin; Drug Administration Schedule; Drug Interactions; Electrocardiography; Female; Humans; Ketoconazole; Ketolides; Kidney Diseases; Male; Metabolic Clearance Rate; Middle Aged	2005
Five-day telithromycin once daily is as effective as 10-day clarithromycin twice daily for the treatment of acute exacerbations of chronic bronchitis and is associated with reduced health-care resource utilization. Chest, 2005, Volume: 128, Issue:4 Topics: Acute Disease; Adult; Aged; Bronchitis; Chronic Disease; Clarithromycin; Disease Progression; Double-Blind Method; Drug Administration Schedule; Female; Forced Expiratory Volume; Health Care Rationing; Humans; Ketolides; Male; Middle Aged; Single-Blind Method; Smoking; Vital Capacity	2005
[Efficacy and safety of extended-release clarithromycin (5-day short-course) vs telithromycin, in acute bacterial exacerbation of chronic bronchitis]. Medecine et maladies infectieuses, 2005, Volume: 35, Issue:10 Topics: Aged; Anti-Bacterial Agents; Clarithromycin; Delayed-Action Preparations; Double-Blind Method; Drug Administration Schedule; Female; Humans; Ketolides; Male; Middle Aged; Patient Selection; Treatment Outcome	2005
Role for 5-day, once-daily extended-release clarithromycin in acute bacterial exacerbation of chronic bronchitis. Current medical research and opinion, 2007, Volume: 23, Issue:2 Topics: Acute Disease; Aged; Anti-Bacterial Agents; Bronchitis; Clarithromycin; Delayed-Action Preparations; Disease Progression; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Ketolides; Male; Middle Aged; Research Design; Severity of Illness Index; Sputum; Treatment Outcome	2007

Other Studies

48 other study(ies) available for clarithromycin and ru 66647

Article	Year
Comparative antianaerobic activities of the ketolides HMR 3647 (RU 66647) and HMR 3004 (RU 64004). Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:9 Topics: Anti-Bacterial Agents; Azithromycin; Bacteria, Anaerobic; Carbon Dioxide; Clarithromycin; Erythromycin; Hydrogen-Ion Concentration; Ketolides; Macrolides; Microbial Sensitivity Tests; Roxithromycin	1997
In vitro susceptibilities of Bordetella pertussis and Bordetella parapertussis to two ketolides (HMR 3004 and HMR 3647), four macrolides (azithromycin, clarithromycin, erythromycin A, and roxithromycin), and two ansamycins (rifampin and rifapentine). Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:4 Topics: Anti-Bacterial Agents; Azithromycin; Bordetella; Bordetella pertussis; Clarithromycin; Erythromycin; Ketolides; Macrolides; Microbial Sensitivity Tests; Rifabutin; Rifampin; Roxithromycin	1998
Activities of HMR 3004 (RU 64004) and HMR 3647 (RU 66647) compared to those of erythromycin, azithromycin, clarithromycin, roxithromycin, and eight other antimicrobial agents against unusual aerobic and anaerobic human and animal bite pathogens isolated f Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:5 Topics: Animals; Anti-Bacterial Agents; Azithromycin; Bacteria, Aerobic; Bacteria, Anaerobic; Bites, Human; Clarithromycin; Erythromycin; Humans; Ketolides; Macrolides; Microbial Sensitivity Tests; Roxithromycin; Skin Diseases, Bacterial; Soft Tissue Infections; Wounds and Injuries	1998
Activity of telithromycin (HMR 3647) against anaerobic bacteria compared to those of eight other agents by time-kill methodology. Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:8 Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Azithromycin; Bacteria, Anaerobic; beta-Lactamases; Clarithromycin; Clindamycin; Drug Therapy, Combination; Erythromycin; Gram-Negative Anaerobic Bacteria; Gram-Positive Bacteria; Ketolides; Macrolides; Metronidazole; Microbial Sensitivity Tests; Roxithromycin; Virginiamycin	1999
Activities of telithromycin (HMR 3647, RU 66647) compared to those of erythromycin, azithromycin, clarithromycin, roxithromycin, and other antimicrobial agents against unusual anaerobes. Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:11 Topics: Anti-Bacterial Agents; Azithromycin; Bacteria, Anaerobic; Bacterial Infections; Clarithromycin; Humans; Ketolides; Macrolides; Microbial Sensitivity Tests; Roxithromycin	1999
Macrolide-ketolide inhibition of MLS-resistant ribosomes is improved by alternative drug interaction with domain II of 23S rRNA. Molecular microbiology, 2000, Volume: 36, Issue:1 Topics: Anti-Bacterial Agents; Base Sequence; Binding Sites; Clarithromycin; Drug Interactions; Drug Resistance, Microbial; Erythromycin; Escherichia coli; Ketolides; Macrolides; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Protein Synthesis Inhibitors; Ribosomes; RNA, Ribosomal, 23S	2000
In vitro activities of the ketolides telithromycin (HMR 3647) and HMR 3004 compared to those of clarithromycin against slowly growing mycobacteria at pHs 6.8 and 7.4. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:10 Topics: Anti-Bacterial Agents; Clarithromycin; Culture Media; Hydrogen-Ion Concentration; Ketolides; Macrolides; Microbial Sensitivity Tests; Mycobacterium	2000
Influence of variations in test methods on susceptibility of Haemophilus influenzae to ampicillin, azithromycin, clarithromycin, and telithromycin. Journal of clinical microbiology, 2001, Volume: 39, Issue:1 Topics: Ampicillin; Anti-Bacterial Agents; Azithromycin; Clarithromycin; Culture Media; Haemophilus Infections; Haemophilus influenzae; Humans; Ketolides; Macrolides; Microbial Sensitivity Tests; Quality Control	2001
Activities of a new fluoroketolide, HMR 3787, and its (des)-fluor derivative RU 64399 compared to those of telithromycin, erythromycin A, azithromycin, clarithromycin, and clindamycin against macrolide-susceptible or -resistant Streptococcus pneumoniae an Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:11 Topics: Anti-Bacterial Agents; Azithromycin; Clarithromycin; Clindamycin; Drug Resistance; Erythromycin; Ketolides; Macrolides; Microbial Sensitivity Tests; Streptococcus pneumoniae; Streptococcus pyogenes	2001
Effect of pH on the susceptibility of Helicobacter pylori to the ketolide telithromycin (HMR 3647) and clarithromycin. The Journal of antimicrobial chemotherapy, 2001, Volume: 48, Issue:5 Topics: Anti-Bacterial Agents; Clarithromycin; Helicobacter pylori; Humans; Hydrogen-Ion Concentration; Ketolides; Macrolides; Microbial Sensitivity Tests	2001
Comparison of telithromycin, a new ketolide, with erythromycin and clarithromycin for the treatment of Haemophilus influenzae pneumonia in suckling, middle aged and senescent mice. International journal of antimicrobial agents, 2002, Volume: 20, Issue:3 Topics: Aging; Animals; Animals, Suckling; Anti-Bacterial Agents; Area Under Curve; Clarithromycin; Drug Administration Schedule; Drug Evaluation, Preclinical; Erythromycin; Haemophilus influenzae; Ketolides; Lung; Macrolides; Mice; Pneumonia, Bacterial; Tissue Distribution	2002
Comparison of the antibacterial activities of ampicillin, ciprofloxacin, clarithromycin, telithromycin and quinupristin/dalfopristin against intracellular non-typeable Haemophilus influenzae. The Journal of antimicrobial chemotherapy, 2002, Volume: 50, Issue:6 Topics: Ampicillin; Anti-Bacterial Agents; Bacterial Typing Techniques; Ciprofloxacin; Clarithromycin; Haemophilus influenzae; Humans; Intracellular Fluid; Ketolides; Macrolides; Microbial Sensitivity Tests; Tumor Cells, Cultured; Virginiamycin	2002
High-level telithromycin resistance in laboratory-generated mutants of Streptococcus pneumoniae. The Journal of antimicrobial chemotherapy, 2003, Volume: 52, Issue:3 Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; Clarithromycin; DNA Primers; Drug Resistance, Bacterial; Erythromycin; Ketolides; Macrolides; Membrane Proteins; Methyltransferases; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Reverse Transcriptase Polymerase Chain Reaction; Ribosomes; Streptococcus pneumoniae	2003
In vitro activity of telithromycin (HMR 3647) against Greek Streptococcus pyogenes and Streptococcus pneumoniae clinical isolates with different macrolide susceptibilities. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2003, Volume: 9, Issue:7 Topics: Anti-Bacterial Agents; Clarithromycin; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Erythromycin; Greece; Ketolides; Macrolides; Streptococcus pneumoniae; Streptococcus pyogenes	2003
[Digitalis -- poisoning, myopathy, ergotism.... When antibiotic and associated therapy become dangerous mixture]. MMW Fortschritte der Medizin, 2003, Sep-25, Volume: 145, Issue:39 Topics: Acetylation; Analgesics, Non-Narcotic; Antacids; Anti-Bacterial Agents; Clarithromycin; Cytochrome P-450 Enzyme System; Digitalis Glycosides; Digoxin; Drug Interactions; Ergotamine; Ergotism; Female; Humans; Hypolipidemic Agents; Ketolides; Macrolides; Middle Aged; Migraine Disorders; Muscular Diseases; Risk Factors; Sinusitis; Vasoconstrictor Agents	2003
[Pharmacoeconomic analysis of community-acquired pneumonia treatment with telithromycin or clarithromycin]. Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2003, Volume: 16, Issue:3 Topics: Anti-Bacterial Agents; Clarithromycin; Community-Acquired Infections; Costs and Cost Analysis; Decision Trees; Economics, Pharmaceutical; Humans; Ketolides; Macrolides; Pneumonia; Randomized Controlled Trials as Topic; Retrospective Studies	2003
Selection of resistance of telithromycin against Haemophilus influenzae, Moraxella catarrhalis and streptococci in comparison with macrolides. The Journal of antimicrobial chemotherapy, 2004, Volume: 54, Issue:2 Topics: Anti-Bacterial Agents; Azithromycin; Clarithromycin; Drug Resistance, Bacterial; Gene Frequency; Haemophilus influenzae; Humans; Ketolides; Macrolides; Microbial Sensitivity Tests; Moraxella catarrhalis; Mutation; Respiratory Tract Infections; Streptococcus; Streptococcus pneumoniae	2004
Antipneumococcal activities of two novel macrolides, GW 773546 and GW 708408, compared with those of erythromycin, azithromycin, clarithromycin, clindamycin, and telithromycin. Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:11 Topics: Anti-Bacterial Agents; Azithromycin; Clarithromycin; Clindamycin; Drug Resistance, Bacterial; Erythromycin; Genes, Bacterial; Ketolides; Macrolides; Microbial Sensitivity Tests; Mutation; Streptococcus pneumoniae; Time Factors	2004
Activities of two novel macrolides, GW 773546 and GW 708408, compared with those of telithromycin, erythromycin, azithromycin, and clarithromycin against Haemophilus influenzae. Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:11 Topics: Anti-Bacterial Agents; Azithromycin; Clarithromycin; Drug Resistance, Bacterial; Erythromycin; Haemophilus influenzae; Ketolides; Macrolides; Microbial Sensitivity Tests; Ribosomal Proteins; RNA, Ribosomal, 23S; Time Factors	2004
23S rRNA base pair 2057-2611 determines ketolide susceptibility and fitness cost of the macrolide resistance mutation 2058A-->G. Proceedings of the National Academy of Sciences of the United States of America, 2005, Apr-05, Volume: 102, Issue:14 Topics: Base Sequence; Binding Sites; Clarithromycin; Drug Resistance, Bacterial; Ketolides; Macrolides; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mycobacterium smegmatis; Nucleic Acid Conformation; Phenotype; Point Mutation; RNA, Bacterial; RNA, Ribosomal, 23S; Species Specificity; Tylosin	2005
Cellular uptake and efflux of azithromycin, erythromycin, clarithromycin, telithromycin, and cethromycin. Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:6 Topics: Animals; Anti-Bacterial Agents; Azithromycin; Cell Line; Clarithromycin; Dogs; Epithelial Cells; Erythromycin; Humans; Ketolides; Macrolides; Mice; Neutrophils; Phagocytes	2005
Molecular basis of macrolide resistance in Campylobacter: role of efflux pumps and target mutations. The Journal of antimicrobial chemotherapy, 2005, Volume: 56, Issue:3 Topics: Anti-Bacterial Agents; Campylobacter; Clarithromycin; Dipeptides; DNA, Ribosomal; Drug Resistance, Multiple, Bacterial; Erythromycin; Ketolides; Macrolides; Membrane Transport Proteins; Microbial Sensitivity Tests; Mutation	2005
Comparative pharmacodynamics of telithromycin and clarithromycin with Streptococcus pneumoniae and Staphylococcus aureus in an in vitro dynamic model: focus on clinically achievable antibiotic concentrations. International journal of antimicrobial agents, 2005, Volume: 26, Issue:3 Topics: Anti-Bacterial Agents; Area Under Curve; Clarithromycin; Colony Count, Microbial; Drug Resistance, Bacterial; Ketolides; Microbial Sensitivity Tests; Staphylococcus aureus; Streptococcus pneumoniae	2005
Kinetic bactericidal activity of telithromycin, azithromycin and clarithromycin against respiratory pathogens. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2005, Volume: 113, Issue:10 Topics: Anti-Bacterial Agents; Azithromycin; Clarithromycin; Haemophilus influenzae; Ketolides; Microbial Sensitivity Tests; Moraxella catarrhalis; Protein Synthesis Inhibitors; Streptococcus; Streptococcus pneumoniae; Time Factors	2005
Effect of efflux on telithromycin and macrolide susceptibility in Haemophilus influenzae. Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:3 Topics: Anti-Bacterial Agents; Azithromycin; Clarithromycin; Drug Resistance, Microbial; Haemophilus Infections; Haemophilus influenzae; Ketolides; Macrolides; Microbial Sensitivity Tests; Time Factors	2006
Efficacy of macrolides and telithromycin against leptospirosis in a hamster model. Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:6 Topics: Animals; Anti-Bacterial Agents; Azithromycin; Clarithromycin; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Doxycycline; Female; Ketolides; Leptospira interrogans; Leptospirosis; Macrolides; Mesocricetus; Serotyping; Species Specificity; Survival Analysis	2006
Telithromycin inhibits the number of viable bacteria but not lymphocyte accumulation in a murine model of chronic respiratory infection. Chemotherapy, 2007, Volume: 53, Issue:1 Topics: Animals; Anti-Bacterial Agents; Biofilms; Chronic Disease; Clarithromycin; Disease Models, Animal; Ketolides; Lung; Lymphocytes; Male; Mice; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections	2007
Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11 Topics: Anti-Bacterial Agents; Aza Compounds; Azithromycin; Clarithromycin; Clavulanic Acid; Clindamycin; Drug Resistance, Bacterial; Fluoroquinolones; Gemifloxacin; Imipenem; Ketolides; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Streptococcus pneumoniae	2007
Levofloxacin-resistant Helicobacter pylori in Hong Kong. Chemotherapy, 2008, Volume: 54, Issue:1 Topics: Amoxicillin; Anti-Bacterial Agents; Clarithromycin; DNA Gyrase; DNA Mutational Analysis; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Helicobacter Infections; Helicobacter pylori; Hong Kong; Humans; Ketolides; Levofloxacin; Metronidazole; Microbial Sensitivity Tests; Ofloxacin; Point Mutation; Tetracycline	2008
Subinhibitory concentrations of telithromycin, clarithromycin and azithromycin reduce methicillin-resistant Staphylococcus aureus coagulase in vitro and in vivo. The Journal of antimicrobial chemotherapy, 2008, Volume: 61, Issue:3 Topics: Animals; Azithromycin; Clarithromycin; Coagulase; Enzyme Inhibitors; Humans; Ketolides; Male; Methicillin Resistance; Mice; Staphylococcus aureus	2008
In vitro activity of telithromycin against Haemophilus influenzae at epithelial lining fluid concentrations. BMC microbiology, 2008, Jan-29, Volume: 8 Topics: Anti-Bacterial Agents; Azithromycin; beta-Lactamases; Carbon Dioxide; Clarithromycin; Haemophilus Infections; Haemophilus influenzae; Humans; Ketolides; Microbial Sensitivity Tests; Respiratory Tract Infections; Time Factors	2008
The intracellular accumulation of phagocytic and epithelial cells and the inhibitory effect on Chlamydophila (Chlamydia) pneumoniae of telithromycin and comparator antimicrobials. Journal of chemotherapy (Florence, Italy), 2008, Volume: 20, Issue:4 Topics: Anti-Bacterial Agents; Cell Line; Chlamydophila pneumoniae; Ciprofloxacin; Clarithromycin; Dose-Response Relationship, Drug; Epithelial Cells; Erythromycin; Humans; Ketolides; Microbial Sensitivity Tests; Minocycline; Phagocytes	2008
Different effects of telithromycin on MUC5AC production induced by human neutrophil peptide-1 or lipopolysaccharide in NCI-H292 cells compared with azithromycin and clarithromycin. The Journal of antimicrobial chemotherapy, 2009, Volume: 63, Issue:1 Topics: alpha-Defensins; Anti-Bacterial Agents; Azithromycin; Cell Line; Clarithromycin; Enzyme-Linked Immunosorbent Assay; Humans; Ketolides; Lipopolysaccharides; Mitogen-Activated Protein Kinase 3; Mucin 5AC; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction	2009
Pharmacodynamic target attainment potential of azithromycin, clarithromycin, and telithromycin in serum and epithelial lining fluid of community-acquired pneumonia patients with penicillin-susceptible, intermediate, and resistant Streptococcus pneumoniae. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2009, Volume: 13, Issue:4 Topics: Anti-Bacterial Agents; Area Under Curve; Azithromycin; Clarithromycin; Community-Acquired Infections; Drug Resistance, Bacterial; Humans; Ketolides; Microbial Sensitivity Tests; Monte Carlo Method; Pneumonia, Pneumococcal; Probability; Streptococcus pneumoniae	2009
Synthesis of novel macrolide derivatives with imidazo[4,5-b]pyridinyl sulfur contained alkyl side chains and their antibacterial activity. Bioorganic & medicinal chemistry letters, 2009, Aug-01, Volume: 19, Issue:15 Topics: Anti-Bacterial Agents; Chemistry, Pharmaceutical; Clarithromycin; Drug Design; Drug Resistance, Multiple, Bacterial; Erythromycin; Humans; Imidazoles; Ketolides; Macrolides; Microbial Sensitivity Tests; Models, Chemical; Respiratory Tract Infections; Staphylococcus aureus; Streptococcus pneumoniae; Sulfides; Sulfur	2009
Azithromycin, clarithromycin and telithromycin inhibit MUC5AC induction by Chlamydophila pneumoniae in airway epithelial cells. Pulmonary pharmacology & therapeutics, 2009, Volume: 22, Issue:6 Topics: Animals; Anti-Bacterial Agents; Azithromycin; Blotting, Western; Cells, Cultured; Chlamydophila Infections; Chlamydophila pneumoniae; Clarithromycin; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Ketolides; Mice; Mucin 5AC; NF-kappa B; NF-kappa B p50 Subunit; Respiratory Mucosa; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factor RelA	2009
Distribution characteristics of telithromycin, a novel ketolide antimicrobial agent applied for treatment of respiratory infection, in lung epithelial lining fluid and alveolar macrophages. Drug metabolism and pharmacokinetics, 2009, Volume: 24, Issue:5 Topics: Animals; Bronchoalveolar Lavage Fluid; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Line; Clarithromycin; Epithelial Cells; Humans; Ketolides; Macrophages, Alveolar; Male; Rats; Rats, Sprague-Dawley; Rotenone	2009
Telithromycin blocks neuromuscular transmission and inhibits nAChR currents in vitro. Toxicology letters, 2010, May-04, Volume: 194, Issue:3 Topics: Animals; Anti-Bacterial Agents; Cell Line; Clarithromycin; Dose-Response Relationship, Drug; Humans; Ketolides; Male; Muscle Contraction; Muscle, Skeletal; Neuromuscular Blocking Agents; Nicotinic Antagonists; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Synaptic Potentials; Tubocurarine	2010
CEM-101 activity against Gram-positive organisms. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5 Topics: Anti-Bacterial Agents; Azithromycin; Ceftriaxone; Clarithromycin; Drug Resistance, Bacterial; Drug Synergism; Erythromycin; Gentamicins; Gram-Positive Bacteria; Ketolides; Macrolides; Microbial Sensitivity Tests; Ofloxacin; Staphylococcus aureus; Staphylococcus epidermidis; Streptococcus pneumoniae; Streptococcus pyogenes; Triazoles; Trimethoprim, Sulfamethoxazole Drug Combination; Vancomycin	2010
Disposition of oral telithromycin in foals and in vitro activity of the drug against macrolide-susceptible and macrolide-resistant Rhodococcus equi isolates. Journal of veterinary pharmacology and therapeutics, 2010, Volume: 33, Issue:4 Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Azithromycin; Bronchoalveolar Lavage; Bronchoalveolar Lavage Fluid; Clarithromycin; Drug Resistance, Bacterial; Epithelium; Erythromycin; Female; Horses; Ketolides; Linear Models; Lung; Macrolides; Male; Microbial Sensitivity Tests; Rhodococcus equi	2010
In vitro intracellular activity and in vivo efficacy of modithromycin, a novel bicyclolide, against Legionella pneumophila. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:4 Topics: Animals; Anti-Bacterial Agents; Azithromycin; Bridged-Ring Compounds; Cell Line; Cells, Cultured; Clarithromycin; Disease Models, Animal; Humans; Ketolides; Legionella pneumophila; Legionnaires' Disease; Levofloxacin; Macrolides; Mice; Microbial Sensitivity Tests; Ofloxacin	2011
Clarithromycin and telithromycin increases interleukin-10 expression in the rat endometriosis model. Cytokine, 2011, Volume: 55, Issue:3 Topics: Animals; Chemokine CCL2; Clarithromycin; Endometriosis; Female; Interleukin-10; Interleukin-6; Ketolides; Peritoneum; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA, Messenger; Uterus	2011
Anti-inflammatory effects of garenoxacin on IL-8 production and ERK1/2 activation induced by lipopolysaccharides in A549 and THP-1 cells. European journal of pharmacology, 2011, Oct-01, Volume: 668, Issue:1-2 Topics: Ampicillin; Anti-Inflammatory Agents; Cell Line; Clarithromycin; Enzyme Activation; Fluoroquinolones; Humans; Immunologic Factors; Interleukin-8; Ketolides; Lipopolysaccharides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; RNA, Messenger	2011
Investigating the barriers to bioavailability of macrolide antibiotics in the rat. European journal of drug metabolism and pharmacokinetics, 2012, Volume: 37, Issue:3 Topics: Animals; Anti-Bacterial Agents; Biological Availability; Clarithromycin; Erythromycin; Hepatocytes; Ketolides; Macrolides; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Roxithromycin	2012
Synthesis and antibacterial activity of a novel series of acylides active against community acquired respiratory pathogens. Bioorganic & medicinal chemistry letters, 2012, Jan-01, Volume: 22, Issue:1 Topics: Anti-Bacterial Agents; Chemistry, Pharmaceutical; Clarithromycin; Drug Design; Drug Resistance, Bacterial; Haemophilus influenzae; Humans; Ketolides; Microbial Sensitivity Tests; Models, Chemical; Nitrogen; Respiratory Tract Infections; Streptococcus pneumoniae	2012
Transport characteristics of clarithromycin, azithromycin and telithromycin, antibiotics applied for treatment of respiratory infections, in Calu-3 cell monolayers as model lung epithelial cells. Die Pharmazie, 2012, Volume: 67, Issue:5 Topics: Adenosine Triphosphatases; Algorithms; Animals; Anti-Bacterial Agents; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azithromycin; Biological Transport, Active; Cell Line; Clarithromycin; Epithelial Cells; Ketolides; Lung; Mice; Multidrug Resistance-Associated Proteins; Protein Binding; Respiratory Tract Infections	2012
Pharmacokinetic modelling of serum and bronchial concentrations for clarithromycin and telithromycin, and site-specific pharmacodynamic simulation for their dosages. Journal of clinical pharmacy and therapeutics, 2014, Volume: 39, Issue:4 Topics: Anti-Bacterial Agents; Area Under Curve; Bacteria; Bronchi; Clarithromycin; Computer Simulation; Dose-Response Relationship, Drug; Epithelium; Humans; Ketolides; Microbial Sensitivity Tests; Models, Biological; Nonlinear Dynamics; Respiratory Tract Infections; Tissue Distribution	2014
Involvement of intestinal permeability in the oral absorption of clarithromycin and telithromycin. Biopharmaceutics & drug disposition, 2014, Volume: 35, Issue:6 Topics: Administration, Oral; Animals; Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily B; Biological Availability; Caco-2 Cells; Clarithromycin; Humans; Intestinal Absorption; Intestinal Mucosa; Ketolides; Liver; Male; Multidrug Resistance-Associated Proteins; Permeability; Rats, Wistar	2014