Page last updated: 2024-08-25

clarithromycin and rivaroxaban

clarithromycin has been researched along with rivaroxaban in 7 studies

Research

Studies (7)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	5 (71.43)	24.3611
2020's	2 (28.57)	2.80

Authors

Authors	Studies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Becka, M; Kubitza, D; Mueck, W	1
Fralick, M; Juurlink, DN; Marras, T	1
Azizi, M; Beaune, P; Blanchard, A; Delavenne, X; Funck-Brentano, C; Gaussem, P; Gouin-Thibault, I; Loriot, MA; Mismetti, P; Narjoz, C; Salem, JE; Siguret, V	1
Ge, W; Jiang, Q; Xu, R	1
Carrier, M; Clark, EG; Garg, AX; Harel, Z; Hill, K; Hundemer, GL; Knoll, G; McArthur, E; Rhodes, E; Sood, MM; Sucha, E	1
Cui, C; Lai, X; Li, H; Liu, D; Sia, JEV; Wu, X; Zhang, F	1

Trials

2 trial(s) available for clarithromycin and rivaroxaban

Article	Year
Co-administration of rivaroxaban with drugs that share its elimination pathways: pharmacokinetic effects in healthy subjects. British journal of clinical pharmacology, 2013, Volume: 76, Issue:3 Topics: Adolescent; Adult; Anticoagulants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Clarithromycin; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Erythromycin; Humans; Ketoconazole; Metabolic Clearance Rate; Midazolam; Middle Aged; Morpholines; Rivaroxaban; Substrate Specificity; Thiophenes; Young Adult	2013
Interindividual variability in dabigatran and rivaroxaban exposure: contribution of ABCB1 genetic polymorphisms and interaction with clarithromycin. Journal of thrombosis and haemostasis : JTH, 2017, Volume: 15, Issue:2 Topics: Adolescent; Adult; Alleles; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Clarithromycin; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dabigatran; Genotype; Heterozygote; Homozygote; Humans; Male; Middle Aged; Mutation; Polymorphism, Genetic; Rivaroxaban; Young Adult	2017

Article

Year

Co-administration of rivaroxaban with drugs that share its elimination pathways: pharmacokinetic effects in healthy subjects.

British journal of clinical pharmacology, 2013, Volume: 76, Issue:3

Topics: Adolescent; Adult; Anticoagulants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Clarithromycin; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Erythromycin; Humans; Ketoconazole; Metabolic Clearance Rate; Midazolam; Middle Aged; Morpholines; Rivaroxaban; Substrate Specificity; Thiophenes; Young Adult

2013

Interindividual variability in dabigatran and rivaroxaban exposure: contribution of ABCB1 genetic polymorphisms and interaction with clarithromycin.

Journal of thrombosis and haemostasis : JTH, 2017, Volume: 15, Issue:2

Topics: Adolescent; Adult; Alleles; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Clarithromycin; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dabigatran; Genotype; Heterozygote; Homozygote; Humans; Male; Middle Aged; Mutation; Polymorphism, Genetic; Rivaroxaban; Young Adult

2017

Other Studies

5 other study(ies) available for clarithromycin and rivaroxaban

Article	Year
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Bleeding associated with coadministration of rivaroxaban and clarithromycin. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Jun-14, Volume: 188, Issue:9 Topics: Aged; Anti-Bacterial Agents; Clarithromycin; Drug Interactions; Factor Xa Inhibitors; Humans; Intracranial Hemorrhages; Male; Rivaroxaban; Tomography, X-Ray Computed	2016
Application of physiologically based pharmacokinetic modeling to the prediction of drug-drug and drug-disease interactions for rivaroxaban. European journal of clinical pharmacology, 2018, Volume: 74, Issue:6 Topics: Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Clarithromycin; Computer Simulation; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Factor Xa Inhibitors; Humans; Ketoconazole; Liver Diseases; Male; Models, Biological; Renal Insufficiency; Ritonavir; Rivaroxaban	2018
Risk of Hospitalization With Hemorrhage Among Older Adults Taking Clarithromycin vs Azithromycin and Direct Oral Anticoagulants. JAMA internal medicine, 2020, 08-01, Volume: 180, Issue:8 Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Azithromycin; Clarithromycin; Dabigatran; Drug Interactions; Factor Xa Inhibitors; Female; Hemorrhage; Hospitalization; Humans; Male; Pyrazoles; Pyridones; Retrospective Studies; Risk Factors; Rivaroxaban	2020
Physiologically-based pharmacokinetic modeling to predict drug-drug interactions of dabigatran etexilate and rivaroxaban in the Chinese older adults. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2023, Mar-01, Volume: 182 Topics: Administration, Oral; Aged; Anticoagulants; ATP Binding Cassette Transporter, Subfamily B, Member 1; China; Clarithromycin; Dabigatran; Drug Interactions; East Asian People; Humans; Rivaroxaban; Verapamil	2023