clarithromycin has been researched along with methotrexate in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (26.09) | 29.6817 |
| 2010's | 16 (69.57) | 24.3611 |
| 2020's | 1 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, X; Lin, X; Skolnik, S; Wang, J | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Ashihara, E; Fujita, N; Hatsuse, M; Inaba, T; Nakagawa, M; Noda, Y; Ochiai, N; Okano, A; Shimazaki, C; Takahashi, R | 1 |
| Böcher, W; Galle, PR; Märker-Hermann, E | 1 |
| Abdi-Ali, L; Baiardi, P; Benucci, M; Bucci, M; Cirino, G; Manfredi, M; Saviola, G | 1 |
| Azevedo, F; Baudrier, T; Duarte, AF; Ferreira, O; Mota, A; Simões, JS | 1 |
| Caron, J; Dereure, O; Fabre, S; Godreuil, S; Guillot, B; Michot, C | 1 |
| Cheng, AL; Huang, HC; Kuo, SH; Lin, CW | 1 |
| Cağlayan Yeğen, B; Can, G; Deniz, M; Duman, DG; Ercan, F; Kumral, ZN | 1 |
| Abdi-Ali, L; Baiardi, P; Benucci, M; Bucci, M; Campostrini, L; Cirino, G; Manfredi, M; Sacco, S; Saviola, G | 1 |
| Hosoda, C; Ishiguro, T; Kanegane, H; Shimizu, Y; Takayanagi, N | 1 |
2 review(s) available for clarithromycin and methotrexate
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Subcutaneous infection with Mycobacterium fortuitum after allogeneic bone marrow transplantation.
Topics: Adult; Bone Marrow Transplantation; Clarithromycin; Combined Modality Therapy; Cyclosporine; Debridement; Drug Therapy, Combination; Female; Graft vs Host Disease; Humans; Immunocompromised Host; Immunosuppressive Agents; Methotrexate; Minocycline; Mycobacterium fortuitum; Mycobacterium Infections, Nontuberculous; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Skin Ulcer; Tacrolimus; Transplantation Conditioning; Transplantation, Homologous | 2001 |
1 trial(s) available for clarithromycin and methotrexate
| Article | Year |
|---|---|
Clarithromycin in rheumatoid arthritis: the addition to methotrexate and low-dose methylprednisolone induces a significant additive value--a 24-month single-blind pilot study.
Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Clarithromycin; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Methylprednisolone; Middle Aged; Pilot Projects; Single-Blind Method; Treatment Outcome | 2013 |
20 other study(ies) available for clarithromycin and methotrexate
| Article | Year |
|---|---|
Rational use of in vitro P-glycoprotein assays in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera | 2001 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
[Skin nodules and ulcers of the limbs in a patient with rheumatoid arthritis].
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antirheumatic Agents; Antitubercular Agents; Arthritis, Rheumatoid; Biopsy; Ciprofloxacin; Clarithromycin; Diagnosis, Differential; Drug Therapy, Combination; Ethambutol; Extremities; Glucocorticoids; Humans; Immunocompromised Host; Male; Methotrexate; Middle Aged; Mycobacterium Infections, Nontuberculous; Mycobacterium marinum; Prednisolone; Skin Diseases, Bacterial; Skin Ulcer; Vasculitis | 2002 |
Clarithromycin in adult-onset Still's disease: a study of 6 cases.
Topics: Adult; Anti-Bacterial Agents; Clarithromycin; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Male; Methotrexate; Still's Disease, Adult-Onset; Treatment Outcome; Young Adult | 2010 |
[A cutaneous infection by Mycobacterium chelonae in a patient with rheumatoid arthritis].
Topics: Anti-Bacterial Agents; Arthritis, Rheumatoid; Ciprofloxacin; Clarithromycin; Drug Combinations; Female; Glucosamine; Humans; Immunosuppressive Agents; Leg; Methotrexate; Middle Aged; Mycobacterium chelonae; Mycobacterium Infections, Nontuberculous; Sulfasalazine; Tuberculosis, Cutaneous | 2010 |
Aggressive cutaneous infection with Mycobacterium marinum in two patients receiving anti-tumor necrosis factor-alfa agents.
Topics: Adult; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Arthritis, Psoriatic; Arthritis, Rheumatoid; Bacterial Typing Techniques; Clarithromycin; Ethambutol; Female; Fingers; Fishes; Hand Dermatoses; Humans; Immunocompromised Host; Immunosuppressive Agents; Infliximab; Methotrexate; Middle Aged; Minocycline; Mycobacterium Infections, Nontuberculous; Mycobacterium marinum; Rifabutin; Skin Diseases, Bacterial; Tumor Necrosis Factor-alpha | 2011 |
Primary central nervous system diffuse large B cell lymphoma transformed from orbital mucosa-associated lymphoid tissue lymphoma: complete response to combined intrathecal and systemic rituximab.
Topics: Adult; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Clarithromycin; Cranial Irradiation; Cyclophosphamide; Disease Progression; Etoposide; Humans; Immunophenotyping; Immunosuppressive Agents; Injections, Spinal; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Large B-Cell, Diffuse; Male; Meningeal Neoplasms; Methotrexate; Methylprednisolone Hemisuccinate; Orbital Neoplasms; Prednisolone; Remission Induction; Rituximab; Vincristine | 2013 |
Saccharomyces boulardii ameliorates clarithromycin- and methotrexate-induced intestinal and hepatic injury in rats.
Topics: Animals; Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Antioxidants; Chemical and Drug Induced Liver Injury; Clarithromycin; Diarrhea; Gastrointestinal Transit; Glutathione; Ileum; Inflammation; Intestinal Diseases; Lipid Peroxidation; Liver; Male; Malondialdehyde; Methotrexate; Neutrophil Infiltration; Oxidative Stress; Peroxidase; Probiotics; Rats; Rats, Sprague-Dawley; Saccharomyces | 2013 |
Topics: Aged; Anti-Bacterial Agents; Antitubercular Agents; Bronchoalveolar Lavage Fluid; Bronchoscopy; Clarithromycin; Ethambutol; Glucocorticoids; Humans; Immunocompromised Host; Immunosuppressive Agents; Male; Methotrexate; Mycobacterium; Mycobacterium Infections, Nontuberculous; Nucleic Acid Amplification Techniques; Polymyalgia Rheumatica; Polyps; Prednisolone; Pulmonary Atelectasis; Rifampin; Tomography, X-Ray Computed; Treatment Outcome; Tuberculosis, Pulmonary | 2020 |