Page last updated: 2024-08-25

clarithromycin and fluconazole

clarithromycin has been researched along with fluconazole in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (21.21)18.2507
2000's9 (27.27)29.6817
2010's16 (48.48)24.3611
2020's1 (3.03)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, X; Lin, X; Skolnik, S; Wang, J1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bharate, SS; Vishwakarma, RA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Tseng, AL; Walmsley, SL1
Althaus, C; Becker, K; Schimkat, M; Sundmacher, R1
Brettle, RP1
Jordan, MK; Kelly, G; Masur, H; Narang, PK; Piscitelli, SC; Polis, MA1
Cheng, B1
Bowersox, J1
Schouten, JT; Whittemore, S1
De Bruin, ML; Herings, RM; Hoes, AW; Leufkens, HG; Panneman, MJ1
Bhaloo, S; Prasad, GV1
Chang, HT; Jung, S; Schelper, RL; Visvesvara, GS1
Greenspan, DL; Hooton, TM; Jacobson, M; Slattery, JT; Trapnell, CB; Unadkat, JD; Winter, HR2
Cameron, DW; Elgadi, M; la Porte, CJ; Sabo, JP1
Kekulé, AS; Kreft, B; Lübbert, C; Marsch, WC; Oehme, A1
Elsisi, AE; Hegazy, SK; Mabrouk, MM; Mansour, NO1
Benne, MS; Greupink, R; Huisman, MT; Russel, FG; Schreurs, M1
Gianni, C1
Andersen, SE; Buch, T1
Daali, Y; Desmeules, JA; Marsousi, N; Rudaz, S1
Ogawa, SI; Shimizu, M; Yamazaki, H1

Reviews

4 review(s) available for clarithromycin and fluconazole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Rifabutin-associated uveitis.
    The Annals of pharmacotherapy, 1995, Volume: 29, Issue:11

    Topics: Anti-Bacterial Agents; Antifungal Agents; Clarithromycin; Clinical Trials as Topic; Drug Interactions; Fluconazole; Humans; Mycobacterium avium-intracellulare Infection; Rifabutin; Uveitis

1995
Mycobacterium avium intracellulare infection in patients with HIV or AIDS.
    The Journal of antimicrobial chemotherapy, 1997, Volume: 40, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Antibiotic Prophylaxis; Antifungal Agents; Azithromycin; Clarithromycin; Clinical Trials as Topic; Fluconazole; Humans; Immunocompromised Host; Mycobacterium avium-intracellulare Infection; Rifabutin

1997
Balamuthia mandrillaris meningoencephalitis in an immunocompetent patient: an unusual clinical course and a favorable outcome.
    Archives of pathology & laboratory medicine, 2004, Volume: 128, Issue:4

    Topics: Aged; Animals; Brain Neoplasms; Central Nervous System Protozoal Infections; Clarithromycin; Diagnosis, Differential; Drug Therapy, Combination; Epilepsy, Partial, Motor; Female; Fluconazole; Humans; Immunocompetence; Lobosea; Magnetic Resonance Imaging; Meningoencephalitis; New York; Opportunistic Infections; Pentamidine; Soil; Sulfadiazine; Texas

2004

Trials

5 trial(s) available for clarithromycin and fluconazole

ArticleYear
Effects of fluconazole and clarithromycin on rifabutin and 25-O-desacetylrifabutin pharmacokinetics.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:8

    Topics: Adult; Anti-Bacterial Agents; Antibiotics, Antitubercular; Antifungal Agents; Clarithromycin; Drug Interactions; Drug Therapy, Combination; Female; Fluconazole; HIV Infections; Humans; Male; Middle Aged; Rifabutin

2000
The effect of clarithromycin, fluconazole, and rifabutin on sulfamethoxazole hydroxylamine formation in individuals with human immunodeficiency virus infection (AACTG 283).
    Clinical pharmacology and therapeutics, 2004, Volume: 76, Issue:4

    Topics: Adult; Anti-Infective Agents; Area Under Curve; CD4 Lymphocyte Count; Clarithromycin; Drug Interactions; Female; Fluconazole; HIV Infections; HIV-1; Humans; Male; Middle Aged; Rifabutin; Sulfamethoxazole; Trimethoprim, Sulfamethoxazole Drug Combination

2004
The effect of clarithromycin, fluconazole, and rifabutin on dapsone hydroxylamine formation in individuals with human immunodeficiency virus infection (AACTG 283).
    Clinical pharmacology and therapeutics, 2004, Volume: 76, Issue:6

    Topics: Adult; Algorithms; Anti-Bacterial Agents; Antifungal Agents; Area Under Curve; CD4 Lymphocyte Count; Chromatography, High Pressure Liquid; Clarithromycin; Dapsone; Female; Fluconazole; HIV Infections; Humans; Male; Middle Aged; Rifabutin

2004
Interaction studies of tipranavir-ritonavir with clarithromycin, fluconazole, and rifabutin in healthy volunteers.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:1

    Topics: Adolescent; Adult; Anti-HIV Agents; Clarithromycin; Drug Interactions; Female; Fluconazole; HIV Protease Inhibitors; Humans; Male; Middle Aged; Pyridines; Pyrones; Rifabutin; Ritonavir; Sulfonamides

2009
Effect of clarithromycin and fluconazole on the pharmacokinetics of montelukast in human volunteers.
    European journal of clinical pharmacology, 2012, Volume: 68, Issue:9

    Topics: Acetates; Administration, Oral; Adult; Analysis of Variance; Anti-Asthmatic Agents; Anti-Bacterial Agents; Antifungal Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Biotransformation; Chromatography, High Pressure Liquid; Clarithromycin; Cross-Over Studies; Cyclopropanes; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Administration Schedule; Drug Interactions; Egypt; Enzyme Inhibitors; Fluconazole; Half-Life; Humans; Leukotriene Antagonists; Male; Membrane Transport Modulators; Membrane Transport Proteins; Metabolic Clearance Rate; Models, Biological; Quinolines; Sulfides

2012

Other Studies

24 other study(ies) available for clarithromycin and fluconazole

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery.
    Bioorganic & medicinal chemistry letters, 2015, Apr-01, Volume: 25, Issue:7

    Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics

2015
Uveitis associated with rifabutin therapy.
    MMWR. Morbidity and mortality weekly report, 1994, Sep-09, Volume: 43, Issue:35

    Topics: Anti-Bacterial Agents; Clarithromycin; Drug Therapy, Combination; Fluconazole; Humans; Rifabutin; Uveitis

1994
Rifabutin-associated anterior uveitis in patients infected with human immunodeficiency virus.
    German journal of ophthalmology, 1996, Volume: 5, Issue:4

    Topics: Acute Disease; Administration, Oral; Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Antifungal Agents; Clarithromycin; Drug Therapy, Combination; Female; Fluconazole; Follow-Up Studies; Humans; Male; Middle Aged; Mycobacterium avium-intracellulare Infection; Rifabutin; Uveitis, Anterior; Visual Acuity

1996
Preventing opportunistic infections.
    PI perspective, 1995, Issue:no 16

    Topics: Acyclovir; AIDS-Related Opportunistic Infections; Clarithromycin; Clindamycin; Clinical Trials as Topic; Clotrimazole; Cytomegalovirus Infections; Dapsone; Fluconazole; Ganciclovir; Humans; Itraconazole; Leucovorin; Mycobacterium avium-intracellulare Infection; Mycoses; Pentamidine; Pneumonia, Pneumocystis; Pyrimethamine; Rifabutin; Toxoplasmosis; Trimethoprim, Sulfamethoxazole Drug Combination; Valacyclovir; Valine

1995
CPCRA researchers present OI studies at Vancouver.
    NIAID AIDS agenda, 1996

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Antitubercular Agents; Candidiasis; Child; Clarithromycin; Clinical Trials as Topic; DNA, Viral; Drug Therapy, Combination; Ethambutol; Female; Fluconazole; Humans; Isoniazid; Molluscum Contagiosum; Molluscum contagiosum virus; Multicenter Studies as Topic; Mycobacterium avium-intracellulare Infection; Ofloxacin; Patient Compliance; Pyrazinamide; Rifampin; Sequence Analysis, DNA; Tuberculosis

1996
Recent development in the treatment and prevention of disseminated Mycobacterium avium complex (MAC).
    STEP perspective, 1996,Fall, Volume: 8, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antibiotics, Antitubercular; Antifungal Agents; Azithromycin; Clarithromycin; Clinical Trials as Topic; Dexamethasone; Drug Interactions; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Fluconazole; Humans; Mycobacterium avium-intracellulare Infection; Rifabutin; Risk Factors; Uveitis

1996
Use of cisapride with contraindicated drugs in The Netherlands.
    The Annals of pharmacotherapy, 2002, Volume: 36, Issue:2

    Topics: Cisapride; Clarithromycin; Contraindications; Databases, Factual; Drug Interactions; Drug Labeling; Drug Prescriptions; Fluconazole; Follow-Up Studies; Humans; Miconazole; Netherlands; Retrospective Studies

2002
Severe reduction in tacrolimus levels with rifampin despite multiple cytochrome P450 inhibitors: a case report.
    Transplantation proceedings, 2003, Volume: 35, Issue:7

    Topics: Adult; Clarithromycin; Creatinine; Cytochrome P-450 Enzyme Inhibitors; Diltiazem; Drug Interactions; Drug Therapy, Combination; Female; Fluconazole; Humans; Immunosuppressive Agents; Kidney Function Tests; Kidney Transplantation; Rifampin; Tacrolimus

2003
[37-year old patient with fever, diarrhea and lymphadenopathy].
    Der Internist, 2010, Volume: 51, Issue:8

    Topics: Adult; AIDS Serodiagnosis; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Antifungal Agents; Antiretroviral Therapy, Highly Active; Candidiasis, Oral; Ciprofloxacin; Clarithromycin; Diagnosis, Differential; Diarrhea; Drug Therapy, Combination; Fever of Unknown Origin; Fluconazole; Giardia lamblia; Giardiasis; HIV Seropositivity; HIV-1; Homosexuality, Male; Humans; Immunoblotting; Lymphatic Diseases; Male; Metronidazole; Omeprazole

2010
Semi-mechanistic physiologically-based pharmacokinetic modeling of clinical glibenclamide pharmacokinetics and drug-drug-interactions.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2013, Aug-16, Volume: 49, Issue:5

    Topics: Animals; Anti-Infective Agents; CHO Cells; Clarithromycin; Computer Simulation; Cricetulus; Cytochrome P-450 Enzyme System; Drug Interactions; Fluconazole; Glyburide; HEK293 Cells; Humans; Hypoglycemic Agents; Models, Biological; Rifampin

2013
Treatment and prevention of paronychia using a new combination of topicals: report of 30 cases.
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2015, Volume: 150, Issue:4

    Topics: Administration, Topical; Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antifungal Agents; Chronic Disease; Clarithromycin; Dermatologic Agents; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluconazole; Follow-Up Studies; Humans; Imidazoles; Male; Middle Aged; Nail Diseases; Occupational Diseases; Paronychia; Polymers; Pyridones; Young Adult

2015
[Combination therapy with fluconazole and other QTc-prolonging drugs increase the QTc interval].
    Ugeskrift for laeger, 2015, Oct-05, Volume: 177, Issue:41

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Antifungal Agents; Clarithromycin; Combined Modality Therapy; Drug Interactions; Electrocardiography; Fluconazole; Heart Rate; Humans; Long QT Syndrome; Male

2015
Prediction of drug-drug interactions using physiologically-based pharmacokinetic models of CYP450 modulators included in Simcyp software.
    Biopharmaceutics & drug disposition, 2018, Volume: 39, Issue:1

    Topics: Ciprofloxacin; Clarithromycin; Computer Simulation; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A Inhibitors; Cytochrome P-450 Enzyme Inducers; Drug Interactions; Fluconazole; Humans; Itraconazole; Ketoconazole; Models, Biological; Paroxetine; Quinidine; Rifampin; Software

2018
Modelled plasma concentrations of pemafibrate with co-administered typical cytochrome P450 inhibitors clopidogrel, fluconazole or clarithromycin predicted by physiologically based pharmacokinetic modelling in virtual populations.
    Xenobiotica; the fate of foreign compounds in biological systems, 2020, Volume: 50, Issue:12

    Topics: Benzoxazoles; Butyrates; Clarithromycin; Clopidogrel; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Fluconazole; Humans; Liver; Pharmaceutical Preparations

2020