Page last updated: 2024-08-25

clarithromycin and digoxin

clarithromycin has been researched along with digoxin in 45 studies

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (22.22)18.2507
2000's22 (48.89)29.6817
2010's12 (26.67)24.3611
2020's1 (2.22)2.80

Authors

AuthorsStudies
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, X; Lin, X; Skolnik, S; Wang, J1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Esaki, T; Kawashima, H; Komura, H; Kuroda, M; Mizuguchi, K; Natsume-Kitatani, Y; Ohashi, R; Watanabe, R1
Etingin, OR; Midoneck, SR1
Baltch, AL; Ford, A; Smith, LC; Smith, RP1
Brown, BA; Griffith, DE; Wallace, RJ; Warden, R1
Alt, M; Arpin-Bott, MP; Guillemet, C; Imler, M1
Laberge, P; Martineau, P1
Hyman, J; Lichstein, E; Trivedi, S1
Guanci, R; Lilley, LL1
Clark, RF; Manoguerra, AS; Nordt, SP; Williams, SR1
Futami, T; Hashida, T; Inui, K; Ito, T; Nohara, R; Sasayama, S; Wakasugi, H; Yano, I1
Ito, S; Juurlink, DN1
Rashkow, A; Xu, H1
Higuchi, S; Ieiri, I; Irie, S; Kimura, M; Kurata, Y; Morita, T; Ohdo, S; Ohtani, H; Otsubo, K; Sawada, Y; Urae, A1
Horga, JF; Pérez-Mateo, M; Reus, S; Tello, A; Torrús, D; Zapater, P1
Kotegawa, T; Kuranari, M; Matsuki, S; Morimoto, T; Nakano, S; Otani, Y; Tsutsumi, K1
Katayama, Y; Kodama, M; Matsumoto, K; Miyatake, K; Tanaka, H; Ueno, K; Yoneda, K1
Juurlink, DN; Kopp, A; Laupacis, A; Mamdani, M; Redelmeier, DA1
Karlstadt, RG; Walker, K1
Burhenne, J; Göggelmann, C; Haefeli, WE; Ludwig, J; Mikus, G; Rengelshausen, J; Riedel, KD; Walter-Sack, I; Weiss, J1
Arnheim, K1
Azam, S; Dhakam, S; Kiran, N1
García-García, JA; Merchante, N; Mira, JA; Vergara-López, S1
Fujita, M; Furukubo, T; Hasegawa, I; Hirata, S; Izumi, S; Ohtani, H; Ota, M; Sawada, Y; Yamakawa, T1
Barone, GW; Breen, P; Carrier, J; Cheboyina, S; Gurley, BJ; Hubbard, MA; Song, PF; Tong, Y; Williams, DK; Yates, CR1
Asahi, S; Ebihara, T; Higuchi, T; Ikemoto, K; Katoh, M; Niwa, S; Takeuchi, T; Yokoi, T; Yoshitomi, S1
Barone, GW; Breen, P; Cheboyina, S; Gurley, BJ; Hubbard, MA; Stuart, LB; Swain, A; Tong, Y; Williams, DK; Yates, CR1
Ito, S; Murakami, H; Nasu, R; Ohtani, H; Sawada, Y; Tsujimoto, M1
Barone, G; Battu, SK; Gurley, BJ; Swain, A; Williams, DK1
Gomes, T; Juurlink, DN; Mamdani, MM1
Chan, AL; Su, CY; Tsai, FH; Wang, MT1
Hu, ZY; Zhao, Y1
Gomes, T; Huang, A; Juurlink, DN; Macdonald, EM; Mamdani, MM; Quinn, KL1
Britz, H; Eissing, T; Frechen, S; Hanke, N; Lehr, T; Moj, D; Wendl, T1
Balzan, D; Callus, R; Delicata, L; Felice, T1

Reviews

2 review(s) available for clarithromycin and digoxin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Clarithromycin-induced digoxin toxicity: a case report and a review of the literature.
    Connecticut medicine, 2001, Volume: 65, Issue:9

    Topics: Aged; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Clarithromycin; Digoxin; Drug Interactions; Female; Humans; Time Factors

2001

Trials

6 trial(s) available for clarithromycin and digoxin

ArticleYear
A prospective study of the clarithromycin-digoxin interaction in elderly patients.
    The Journal of antimicrobial chemotherapy, 2002, Volume: 50, Issue:4

    Topics: Aged; Aged, 80 and over; Bayes Theorem; Clarithromycin; Digoxin; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Patients; Prospective Studies

2002
The effect of erythromycin and clarithromycin on the pharmacokinetics of intravenous digoxin in healthy volunteers.
    Journal of clinical pharmacology, 2002, Volume: 42, Issue:10

    Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Cardiotonic Agents; Clarithromycin; Digoxin; Drug Interactions; Erythromycin; Humans; Infusions, Intravenous; Male; Metabolic Clearance Rate

2002
Effect of clarithromycin on steady-state digoxin concentrations.
    The Annals of pharmacotherapy, 2003, Volume: 37, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; ATP Binding Cassette Transporter, Subfamily B; Clarithromycin; Digoxin; Dose-Response Relationship, Drug; Drug Interactions; Female; Heart Failure; Humans; Male; Middle Aged

2003
Contribution of increased oral bioavailability and reduced nonglomerular renal clearance of digoxin to the digoxin-clarithromycin interaction.
    British journal of clinical pharmacology, 2003, Volume: 56, Issue:1

    Topics: Administration, Oral; Adult; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Area Under Curve; Biological Availability; Clarithromycin; Creatinine; Cross-Over Studies; Digoxin; Double-Blind Method; Drug Interactions; Genes, MDR; Genotype; Humans; Infusions, Intravenous; Kidney; Male; Polymorphism, Genetic; Prospective Studies

2003
Effect of milk thistle (Silybum marianum) and black cohosh (Cimicifuga racemosa) supplementation on digoxin pharmacokinetics in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:1

    Topics: Administration, Oral; Adult; Area Under Curve; Cimicifuga; Clarithromycin; Dietary Supplements; Digoxin; Drug Administration Schedule; Female; Genes, MDR; Half-Life; Haplotypes; Herb-Drug Interactions; Humans; Male; Plant Preparations; Rifampin; Silybum marianum

2006
Effect of goldenseal (Hydrastis canadensis) and kava kava (Piper methysticum) supplementation on digoxin pharmacokinetics in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:2

    Topics: Adult; Cardiotonic Agents; Clarithromycin; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Digoxin; Drug Interactions; Female; Herb-Drug Interactions; Humans; Hydrastis; Kava; Male; Rifampin

2007

Other Studies

37 other study(ies) available for clarithromycin and digoxin

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Development of an
    Journal of medicinal chemistry, 2021, 03-11, Volume: 64, Issue:5

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Cell Line; Computer Simulation; Endothelial Cells; Gene Knockout Techniques; Humans; Organic Chemicals; Rats, Transgenic

2021
Clarithromycin-related toxic effects of digoxin.
    The New England journal of medicine, 1995, Nov-30, Volume: 333, Issue:22

    Topics: Aged; Aged, 80 and over; Atrial Premature Complexes; Bronchitis; Clarithromycin; Digoxin; Drug Interactions; Female; Humans

1995
Clarithromycin-induced digoxin toxicity in a patient with AIDS.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1995, Volume: 21, Issue:4

    Topics: Aged; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Clarithromycin; Digoxin; Drug Interactions; Drug Therapy, Combination; Humans; Male

1995
Clarithromycin-associated digoxin toxicity in the elderly.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1997, Volume: 24, Issue:1

    Topics: Age Factors; Aged; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Antibiotics, Antitubercular; Antitubercular Agents; Atrial Fibrillation; Clarithromycin; Digoxin; Drug Interactions; Drug Therapy, Combination; Echocardiography; Ethambutol; Humans; Male; Mycobacterium avium-intracellulare Infection; Rifabutin

1997
[Clarithromycin-digoxin: an unrecognized interaction in some patients].
    Presse medicale (Paris, France : 1983), 1997, Apr-05, Volume: 26, Issue:11

    Topics: Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Clarithromycin; Digoxin; Drug Interactions; Humans; Male

1997
Clarithromycin-induced digoxin intoxication.
    The Annals of pharmacotherapy, 1997, Volume: 31, Issue:9

    Topics: Aged; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Blood Pressure; Bronchitis; Cardiomyopathies; Clarithromycin; Digoxin; Drug Interactions; Heart Rate; Humans; Kidney Failure, Chronic; Male

1997
Clarithromycin and digoxin toxicity.
    Annals of internal medicine, 1998, Apr-01, Volume: 128, Issue:7

    Topics: Aged; Anti-Bacterial Agents; Clarithromycin; Digoxin; Drug Interactions; Drug Therapy, Combination; Female; Humans

1998
A dangerous combination.
    The American journal of nursing, 1998, Volume: 98, Issue:5

    Topics: Aged; Anti-Bacterial Agents; Cardiotonic Agents; Clarithromycin; Digoxin; Diuretics; Drug Interactions; Furosemide; Heart Diseases; Humans; Male; Medication Errors; Memory

1998
Clarithromycin induced digoxin toxicity.
    Journal of accident & emergency medicine, 1998, Volume: 15, Issue:3

    Topics: Adult; Anorexia; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Clarithromycin; Digoxin; Drug Interactions; Drug Therapy, Combination; Emergency Service, Hospital; Humans; Male; Vomiting

1998
Effect of clarithromycin on renal excretion of digoxin: interaction with P-glycoprotein.
    Clinical pharmacology and therapeutics, 1998, Volume: 64, Issue:1

    Topics: Anti-Arrhythmia Agents; Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Clarithromycin; Digoxin; Drug Interactions; Drug Therapy, Combination; Humans; Male; Metabolic Clearance Rate; Middle Aged

1998
Comment: clarithromycin-digoxin interaction.
    The Annals of pharmacotherapy, 1999, Volume: 33, Issue:12

    Topics: Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cardiotonic Agents; Clarithromycin; Digoxin; Drug Interactions; Humans

1999
Role of human MDR1 gene polymorphism in bioavailability and interaction of digoxin, a substrate of P-glycoprotein.
    Clinical pharmacology and therapeutics, 2002, Volume: 72, Issue:2

    Topics: Administration, Oral; Adult; Alleles; Anti-Bacterial Agents; Area Under Curve; Asian People; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Cardiotonic Agents; Clarithromycin; Cytochrome P-450 Enzyme System; Digoxin; Drug Administration Schedule; Drug Interactions; Enzyme Inhibitors; Genes, MDR; Genotype; Humans; Injections, Intravenous; Japan; Male; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Reference Values

2002
Drug-drug interactions among elderly patients hospitalized for drug toxicity.
    JAMA, 2003, Apr-02, Volume: 289, Issue:13

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Anti-Asthmatic Agents; Anti-Infective Agents; Antihypertensive Agents; Case-Control Studies; Clarithromycin; Contraindications; Digoxin; Diuretics; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Female; Glyburide; Hospitalization; Humans; Hyperkalemia; Hypoglycemia; Male; Ontario; Trimethoprim, Sulfamethoxazole Drug Combination

2003
Update on prescribing information for pantoprazole.
    American family physician, 2003, Mar-15, Volume: 67, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Clarithromycin; Digoxin; Drug Interactions; Esophagitis; Humans; Nifedipine; Omeprazole; Pantoprazole; Proton Pump Inhibitors; Sulfoxides

2003
[Digitalis -- poisoning, myopathy, ergotism.... When antibiotic and associated therapy become dangerous mixture].
    MMW Fortschritte der Medizin, 2003, Sep-25, Volume: 145, Issue:39

    Topics: Acetylation; Analgesics, Non-Narcotic; Antacids; Anti-Bacterial Agents; Clarithromycin; Cytochrome P-450 Enzyme System; Digitalis Glycosides; Digoxin; Drug Interactions; Ergotamine; Ergotism; Female; Humans; Hypolipidemic Agents; Ketolides; Macrolides; Middle Aged; Migraine Disorders; Muscular Diseases; Risk Factors; Sinusitis; Vasoconstrictor Agents

2003
Clarithromycin induced digoxin toxicity: case report and review.
    JPMA. The Journal of the Pakistan Medical Association, 2004, Volume: 54, Issue:8

    Topics: Anti-Bacterial Agents; Anticoagulants; Atrial Fibrillation; Clarithromycin; Digoxin; Drug Interactions; Drug Therapy, Combination; Female; Humans; Middle Aged; Pneumonia, Bacterial; Warfarin

2004
[Digoxin toxicity secondary to inhibition of digoxin intestinal metabolism in a patient receiving clarithromycin].
    Medicina clinica, 2004, Nov-06, Volume: 123, Issue:16

    Topics: Aged; Anti-Bacterial Agents; Cardiotonic Agents; Clarithromycin; Digoxin; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Intestinal Mucosa; Treatment Outcome

2004
Interactions between clarithromycin and digoxin in patients with end-stage renal disease.
    International journal of clinical pharmacology and therapeutics, 2005, Volume: 43, Issue:1

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cardiotonic Agents; Clarithromycin; Digoxin; Drug Interactions; Female; Humans; Kidney Failure, Chronic; Male; Renal Dialysis; Renal Replacement Therapy

2005
Establishment and characterization of the transformants stably-expressing MDR1 derived from various animal species in LLC-PK1.
    Pharmaceutical research, 2006, Volume: 23, Issue:7

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Clarithromycin; Digoxin; Dogs; Dose-Response Relationship, Drug; Haplorhini; Humans; Kinetics; LLC-PK1 Cells; Mice; Pharmaceutical Preparations; Rats; RNA, Messenger; Swine; Transfection; Verapamil; Vinblastine

2006
Effect of macrolide antibiotics on uptake of digoxin into rat liver.
    Biopharmaceutics & drug disposition, 2007, Volume: 28, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Azithromycin; Biological Transport; Blood Flow Velocity; Cardiotonic Agents; Clarithromycin; Digoxin; Dose-Response Relationship, Drug; Drug Interactions; Erythromycin; Hepatocytes; Josamycin; Liver; Macrolides; Male; Permeability; Rats; Rats, Sprague-Dawley; Roxithromycin; Tissue Distribution

2007
Gauging the clinical significance of P-glycoprotein-mediated herb-drug interactions: comparative effects of St. John's wort, Echinacea, clarithromycin, and rifampin on digoxin pharmacokinetics.
    Molecular nutrition & food research, 2008, Volume: 52, Issue:7

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Clarithromycin; Dietary Supplements; Digoxin; Echinacea; Flavonoids; Ginkgo biloba; Herb-Drug Interactions; Hypericum; Rifampin

2008
Macrolide-induced digoxin toxicity: a population-based study.
    Clinical pharmacology and therapeutics, 2009, Volume: 86, Issue:4

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azithromycin; Cardiotonic Agents; Case-Control Studies; Clarithromycin; Comorbidity; Digoxin; Drug Interactions; Erythromycin; Female; Humans; Macrolides; Male; Polypharmacy

2009
Risk of digoxin intoxication caused by clarithromycin-digoxin interactions in heart failure patients: a population-based study.
    European journal of clinical pharmacology, 2009, Volume: 65, Issue:12

    Topics: Aged; Anti-Bacterial Agents; Cardiotonic Agents; Case-Control Studies; Clarithromycin; Cohort Studies; Digoxin; Dose-Response Relationship, Drug; Drug Interactions; Female; Heart Failure; Hospitalization; Humans; Male; Retrospective Studies

2009
Physiologically based pharmacokinetic modelling and in vivo [I]/K(i) accurately predict P-glycoprotein-mediated drug-drug interactions with dabigatran etexilate.
    British journal of pharmacology, 2014, Volume: 171, Issue:4

    Topics: Amiodarone; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; beta-Alanine; Clarithromycin; Dabigatran; Digoxin; Dronedarone; Drug Interactions; Humans; Models, Biological; Pyridines; Quinidine; Verapamil

2014
Macrolides, Digoxin Toxicity and the Risk of Sudden Death: A Population-Based Study.
    Drug safety, 2017, Volume: 40, Issue:9

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Atrial Fibrillation; Azithromycin; Cardiotonic Agents; Case-Control Studies; Cefuroxime; Clarithromycin; Death, Sudden; Digoxin; Drug Interactions; Erythromycin; Female; Heart Failure; Humans; Macrolides; Male; Ontario; Risk Factors

2017
PBPK Models for CYP3A4 and P-gp DDI Prediction: A Modeling Network of Rifampicin, Itraconazole, Clarithromycin, Midazolam, Alfentanil, and Digoxin.
    CPT: pharmacometrics & systems pharmacology, 2018, Volume: 7, Issue:10

    Topics: Alfentanil; ATP Binding Cassette Transporter, Subfamily B, Member 1; Clarithromycin; Cytochrome P-450 CYP3A; Digoxin; Drug Interactions; Humans; Itraconazole; Midazolam; Models, Biological; Rifampin

2018
Digoxin toxicity precipitated by Helicobacter pylori eradication therapy.
    British journal of hospital medicine (London, England : 2005), 2019, Apr-02, Volume: 80, Issue:4

    Topics: Acute Kidney Injury; Aged, 80 and over; Amoxicillin; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Atrial Fibrillation; Bradycardia; Bundle-Branch Block; Clarithromycin; Digoxin; Drug Interactions; Electrocardiography; Female; Helicobacter Infections; Helicobacter pylori; Humans; Hyperkalemia; Immunoglobulin Fab Fragments; Omeprazole; Tachycardia, Ventricular

2019