Page last updated: 2024-08-25

clarithromycin and digoxin

clarithromycin has been researched along with digoxin in 45 studies

Research

Studies (45)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	10 (22.22)	18.2507
2000's	22 (48.89)	29.6817
2010's	12 (26.67)	24.3611
2020's	1 (2.22)	2.80

Authors

Authors	Studies
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, X; Lin, X; Skolnik, S; Wang, J	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Esaki, T; Kawashima, H; Komura, H; Kuroda, M; Mizuguchi, K; Natsume-Kitatani, Y; Ohashi, R; Watanabe, R	1
Etingin, OR; Midoneck, SR	1
Baltch, AL; Ford, A; Smith, LC; Smith, RP	1
Brown, BA; Griffith, DE; Wallace, RJ; Warden, R	1
Alt, M; Arpin-Bott, MP; Guillemet, C; Imler, M	1
Laberge, P; Martineau, P	1
Hyman, J; Lichstein, E; Trivedi, S	1
Guanci, R; Lilley, LL	1
Clark, RF; Manoguerra, AS; Nordt, SP; Williams, SR	1
Futami, T; Hashida, T; Inui, K; Ito, T; Nohara, R; Sasayama, S; Wakasugi, H; Yano, I	1
Ito, S; Juurlink, DN	1
Rashkow, A; Xu, H	1
Higuchi, S; Ieiri, I; Irie, S; Kimura, M; Kurata, Y; Morita, T; Ohdo, S; Ohtani, H; Otsubo, K; Sawada, Y; Urae, A	1
Horga, JF; Pérez-Mateo, M; Reus, S; Tello, A; Torrús, D; Zapater, P	1
Kotegawa, T; Kuranari, M; Matsuki, S; Morimoto, T; Nakano, S; Otani, Y; Tsutsumi, K	1
Katayama, Y; Kodama, M; Matsumoto, K; Miyatake, K; Tanaka, H; Ueno, K; Yoneda, K	1
Juurlink, DN; Kopp, A; Laupacis, A; Mamdani, M; Redelmeier, DA	1
Karlstadt, RG; Walker, K	1
Burhenne, J; Göggelmann, C; Haefeli, WE; Ludwig, J; Mikus, G; Rengelshausen, J; Riedel, KD; Walter-Sack, I; Weiss, J	1
Arnheim, K	1
Azam, S; Dhakam, S; Kiran, N	1
García-García, JA; Merchante, N; Mira, JA; Vergara-López, S	1
Fujita, M; Furukubo, T; Hasegawa, I; Hirata, S; Izumi, S; Ohtani, H; Ota, M; Sawada, Y; Yamakawa, T	1
Barone, GW; Breen, P; Carrier, J; Cheboyina, S; Gurley, BJ; Hubbard, MA; Song, PF; Tong, Y; Williams, DK; Yates, CR	1
Asahi, S; Ebihara, T; Higuchi, T; Ikemoto, K; Katoh, M; Niwa, S; Takeuchi, T; Yokoi, T; Yoshitomi, S	1
Barone, GW; Breen, P; Cheboyina, S; Gurley, BJ; Hubbard, MA; Stuart, LB; Swain, A; Tong, Y; Williams, DK; Yates, CR	1
Ito, S; Murakami, H; Nasu, R; Ohtani, H; Sawada, Y; Tsujimoto, M	1
Barone, G; Battu, SK; Gurley, BJ; Swain, A; Williams, DK	1
Gomes, T; Juurlink, DN; Mamdani, MM	1
Chan, AL; Su, CY; Tsai, FH; Wang, MT	1
Hu, ZY; Zhao, Y	1
Gomes, T; Huang, A; Juurlink, DN; Macdonald, EM; Mamdani, MM; Quinn, KL	1
Britz, H; Eissing, T; Frechen, S; Hanke, N; Lehr, T; Moj, D; Wendl, T	1
Balzan, D; Callus, R; Delicata, L; Felice, T	1

Reviews

2 review(s) available for clarithromycin and digoxin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Clarithromycin-induced digoxin toxicity: a case report and a review of the literature. Connecticut medicine, 2001, Volume: 65, Issue:9 Topics: Aged; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Clarithromycin; Digoxin; Drug Interactions; Female; Humans; Time Factors	2001

Trials

6 trial(s) available for clarithromycin and digoxin

Article	Year
A prospective study of the clarithromycin-digoxin interaction in elderly patients. The Journal of antimicrobial chemotherapy, 2002, Volume: 50, Issue:4 Topics: Aged; Aged, 80 and over; Bayes Theorem; Clarithromycin; Digoxin; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Patients; Prospective Studies	2002
The effect of erythromycin and clarithromycin on the pharmacokinetics of intravenous digoxin in healthy volunteers. Journal of clinical pharmacology, 2002, Volume: 42, Issue:10 Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Cardiotonic Agents; Clarithromycin; Digoxin; Drug Interactions; Erythromycin; Humans; Infusions, Intravenous; Male; Metabolic Clearance Rate	2002
Effect of clarithromycin on steady-state digoxin concentrations. The Annals of pharmacotherapy, 2003, Volume: 37, Issue:2 Topics: Adult; Aged; Aged, 80 and over; ATP Binding Cassette Transporter, Subfamily B; Clarithromycin; Digoxin; Dose-Response Relationship, Drug; Drug Interactions; Female; Heart Failure; Humans; Male; Middle Aged	2003
Contribution of increased oral bioavailability and reduced nonglomerular renal clearance of digoxin to the digoxin-clarithromycin interaction. British journal of clinical pharmacology, 2003, Volume: 56, Issue:1 Topics: Administration, Oral; Adult; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Area Under Curve; Biological Availability; Clarithromycin; Creatinine; Cross-Over Studies; Digoxin; Double-Blind Method; Drug Interactions; Genes, MDR; Genotype; Humans; Infusions, Intravenous; Kidney; Male; Polymorphism, Genetic; Prospective Studies	2003
Effect of milk thistle (Silybum marianum) and black cohosh (Cimicifuga racemosa) supplementation on digoxin pharmacokinetics in humans. Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:1 Topics: Administration, Oral; Adult; Area Under Curve; Cimicifuga; Clarithromycin; Dietary Supplements; Digoxin; Drug Administration Schedule; Female; Genes, MDR; Half-Life; Haplotypes; Herb-Drug Interactions; Humans; Male; Plant Preparations; Rifampin; Silybum marianum	2006
Effect of goldenseal (Hydrastis canadensis) and kava kava (Piper methysticum) supplementation on digoxin pharmacokinetics in humans. Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:2 Topics: Adult; Cardiotonic Agents; Clarithromycin; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Digoxin; Drug Interactions; Female; Herb-Drug Interactions; Humans; Hydrastis; Kava; Male; Rifampin	2007

Other Studies

37 other study(ies) available for clarithromycin and digoxin

Article	Year
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2 Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Development of an Journal of medicinal chemistry, 2021, 03-11, Volume: 64, Issue:5 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Cell Line; Computer Simulation; Endothelial Cells; Gene Knockout Techniques; Humans; Organic Chemicals; Rats, Transgenic	2021
Clarithromycin-related toxic effects of digoxin. The New England journal of medicine, 1995, Nov-30, Volume: 333, Issue:22 Topics: Aged; Aged, 80 and over; Atrial Premature Complexes; Bronchitis; Clarithromycin; Digoxin; Drug Interactions; Female; Humans	1995
Clarithromycin-induced digoxin toxicity in a patient with AIDS. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1995, Volume: 21, Issue:4 Topics: Aged; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Clarithromycin; Digoxin; Drug Interactions; Drug Therapy, Combination; Humans; Male	1995
Clarithromycin-associated digoxin toxicity in the elderly. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1997, Volume: 24, Issue:1 Topics: Age Factors; Aged; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Antibiotics, Antitubercular; Antitubercular Agents; Atrial Fibrillation; Clarithromycin; Digoxin; Drug Interactions; Drug Therapy, Combination; Echocardiography; Ethambutol; Humans; Male; Mycobacterium avium-intracellulare Infection; Rifabutin	1997
[Clarithromycin-digoxin: an unrecognized interaction in some patients]. Presse medicale (Paris, France : 1983), 1997, Apr-05, Volume: 26, Issue:11 Topics: Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Clarithromycin; Digoxin; Drug Interactions; Humans; Male	1997
Clarithromycin-induced digoxin intoxication. The Annals of pharmacotherapy, 1997, Volume: 31, Issue:9 Topics: Aged; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Blood Pressure; Bronchitis; Cardiomyopathies; Clarithromycin; Digoxin; Drug Interactions; Heart Rate; Humans; Kidney Failure, Chronic; Male	1997
Clarithromycin and digoxin toxicity. Annals of internal medicine, 1998, Apr-01, Volume: 128, Issue:7 Topics: Aged; Anti-Bacterial Agents; Clarithromycin; Digoxin; Drug Interactions; Drug Therapy, Combination; Female; Humans	1998
A dangerous combination. The American journal of nursing, 1998, Volume: 98, Issue:5 Topics: Aged; Anti-Bacterial Agents; Cardiotonic Agents; Clarithromycin; Digoxin; Diuretics; Drug Interactions; Furosemide; Heart Diseases; Humans; Male; Medication Errors; Memory	1998
Clarithromycin induced digoxin toxicity. Journal of accident & emergency medicine, 1998, Volume: 15, Issue:3 Topics: Adult; Anorexia; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Clarithromycin; Digoxin; Drug Interactions; Drug Therapy, Combination; Emergency Service, Hospital; Humans; Male; Vomiting	1998
Effect of clarithromycin on renal excretion of digoxin: interaction with P-glycoprotein. Clinical pharmacology and therapeutics, 1998, Volume: 64, Issue:1 Topics: Anti-Arrhythmia Agents; Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Clarithromycin; Digoxin; Drug Interactions; Drug Therapy, Combination; Humans; Male; Metabolic Clearance Rate; Middle Aged	1998
Comment: clarithromycin-digoxin interaction. The Annals of pharmacotherapy, 1999, Volume: 33, Issue:12 Topics: Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cardiotonic Agents; Clarithromycin; Digoxin; Drug Interactions; Humans	1999
Role of human MDR1 gene polymorphism in bioavailability and interaction of digoxin, a substrate of P-glycoprotein. Clinical pharmacology and therapeutics, 2002, Volume: 72, Issue:2 Topics: Administration, Oral; Adult; Alleles; Anti-Bacterial Agents; Area Under Curve; Asian People; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Cardiotonic Agents; Clarithromycin; Cytochrome P-450 Enzyme System; Digoxin; Drug Administration Schedule; Drug Interactions; Enzyme Inhibitors; Genes, MDR; Genotype; Humans; Injections, Intravenous; Japan; Male; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Reference Values	2002
Drug-drug interactions among elderly patients hospitalized for drug toxicity. JAMA, 2003, Apr-02, Volume: 289, Issue:13 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Anti-Asthmatic Agents; Anti-Infective Agents; Antihypertensive Agents; Case-Control Studies; Clarithromycin; Contraindications; Digoxin; Diuretics; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Female; Glyburide; Hospitalization; Humans; Hyperkalemia; Hypoglycemia; Male; Ontario; Trimethoprim, Sulfamethoxazole Drug Combination	2003
Update on prescribing information for pantoprazole. American family physician, 2003, Mar-15, Volume: 67, Issue:6 Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Clarithromycin; Digoxin; Drug Interactions; Esophagitis; Humans; Nifedipine; Omeprazole; Pantoprazole; Proton Pump Inhibitors; Sulfoxides	2003
[Digitalis -- poisoning, myopathy, ergotism.... When antibiotic and associated therapy become dangerous mixture]. MMW Fortschritte der Medizin, 2003, Sep-25, Volume: 145, Issue:39 Topics: Acetylation; Analgesics, Non-Narcotic; Antacids; Anti-Bacterial Agents; Clarithromycin; Cytochrome P-450 Enzyme System; Digitalis Glycosides; Digoxin; Drug Interactions; Ergotamine; Ergotism; Female; Humans; Hypolipidemic Agents; Ketolides; Macrolides; Middle Aged; Migraine Disorders; Muscular Diseases; Risk Factors; Sinusitis; Vasoconstrictor Agents	2003
Clarithromycin induced digoxin toxicity: case report and review. JPMA. The Journal of the Pakistan Medical Association, 2004, Volume: 54, Issue:8 Topics: Anti-Bacterial Agents; Anticoagulants; Atrial Fibrillation; Clarithromycin; Digoxin; Drug Interactions; Drug Therapy, Combination; Female; Humans; Middle Aged; Pneumonia, Bacterial; Warfarin	2004
[Digoxin toxicity secondary to inhibition of digoxin intestinal metabolism in a patient receiving clarithromycin]. Medicina clinica, 2004, Nov-06, Volume: 123, Issue:16 Topics: Aged; Anti-Bacterial Agents; Cardiotonic Agents; Clarithromycin; Digoxin; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Intestinal Mucosa; Treatment Outcome	2004
Interactions between clarithromycin and digoxin in patients with end-stage renal disease. International journal of clinical pharmacology and therapeutics, 2005, Volume: 43, Issue:1 Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cardiotonic Agents; Clarithromycin; Digoxin; Drug Interactions; Female; Humans; Kidney Failure, Chronic; Male; Renal Dialysis; Renal Replacement Therapy	2005
Establishment and characterization of the transformants stably-expressing MDR1 derived from various animal species in LLC-PK1. Pharmaceutical research, 2006, Volume: 23, Issue:7 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Clarithromycin; Digoxin; Dogs; Dose-Response Relationship, Drug; Haplorhini; Humans; Kinetics; LLC-PK1 Cells; Mice; Pharmaceutical Preparations; Rats; RNA, Messenger; Swine; Transfection; Verapamil; Vinblastine	2006
Effect of macrolide antibiotics on uptake of digoxin into rat liver. Biopharmaceutics & drug disposition, 2007, Volume: 28, Issue:3 Topics: Animals; Anti-Bacterial Agents; Azithromycin; Biological Transport; Blood Flow Velocity; Cardiotonic Agents; Clarithromycin; Digoxin; Dose-Response Relationship, Drug; Drug Interactions; Erythromycin; Hepatocytes; Josamycin; Liver; Macrolides; Male; Permeability; Rats; Rats, Sprague-Dawley; Roxithromycin; Tissue Distribution	2007
Gauging the clinical significance of P-glycoprotein-mediated herb-drug interactions: comparative effects of St. John's wort, Echinacea, clarithromycin, and rifampin on digoxin pharmacokinetics. Molecular nutrition & food research, 2008, Volume: 52, Issue:7 Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Clarithromycin; Dietary Supplements; Digoxin; Echinacea; Flavonoids; Ginkgo biloba; Herb-Drug Interactions; Hypericum; Rifampin	2008
Macrolide-induced digoxin toxicity: a population-based study. Clinical pharmacology and therapeutics, 2009, Volume: 86, Issue:4 Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azithromycin; Cardiotonic Agents; Case-Control Studies; Clarithromycin; Comorbidity; Digoxin; Drug Interactions; Erythromycin; Female; Humans; Macrolides; Male; Polypharmacy	2009
Risk of digoxin intoxication caused by clarithromycin-digoxin interactions in heart failure patients: a population-based study. European journal of clinical pharmacology, 2009, Volume: 65, Issue:12 Topics: Aged; Anti-Bacterial Agents; Cardiotonic Agents; Case-Control Studies; Clarithromycin; Cohort Studies; Digoxin; Dose-Response Relationship, Drug; Drug Interactions; Female; Heart Failure; Hospitalization; Humans; Male; Retrospective Studies	2009
Physiologically based pharmacokinetic modelling and in vivo [I]/K(i) accurately predict P-glycoprotein-mediated drug-drug interactions with dabigatran etexilate. British journal of pharmacology, 2014, Volume: 171, Issue:4 Topics: Amiodarone; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; beta-Alanine; Clarithromycin; Dabigatran; Digoxin; Dronedarone; Drug Interactions; Humans; Models, Biological; Pyridines; Quinidine; Verapamil	2014
Macrolides, Digoxin Toxicity and the Risk of Sudden Death: A Population-Based Study. Drug safety, 2017, Volume: 40, Issue:9 Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Atrial Fibrillation; Azithromycin; Cardiotonic Agents; Case-Control Studies; Cefuroxime; Clarithromycin; Death, Sudden; Digoxin; Drug Interactions; Erythromycin; Female; Heart Failure; Humans; Macrolides; Male; Ontario; Risk Factors	2017
PBPK Models for CYP3A4 and P-gp DDI Prediction: A Modeling Network of Rifampicin, Itraconazole, Clarithromycin, Midazolam, Alfentanil, and Digoxin. CPT: pharmacometrics & systems pharmacology, 2018, Volume: 7, Issue:10 Topics: Alfentanil; ATP Binding Cassette Transporter, Subfamily B, Member 1; Clarithromycin; Cytochrome P-450 CYP3A; Digoxin; Drug Interactions; Humans; Itraconazole; Midazolam; Models, Biological; Rifampin	2018
Digoxin toxicity precipitated by Helicobacter pylori eradication therapy. British journal of hospital medicine (London, England : 2005), 2019, Apr-02, Volume: 80, Issue:4 Topics: Acute Kidney Injury; Aged, 80 and over; Amoxicillin; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Atrial Fibrillation; Bradycardia; Bundle-Branch Block; Clarithromycin; Digoxin; Drug Interactions; Electrocardiography; Female; Helicobacter Infections; Helicobacter pylori; Humans; Hyperkalemia; Immunoglobulin Fab Fragments; Omeprazole; Tachycardia, Ventricular	2019