Page last updated: 2024-08-25

clarithromycin and cyclosporine

clarithromycin has been researched along with cyclosporine in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (25.00)18.2507
2000's8 (25.00)29.6817
2010's15 (46.88)24.3611
2020's1 (3.13)2.80

Authors

AuthorsStudies
Hasegawa, T; Hui, CS; Kitaichi, K; Miyamoto, KI; Sakai, M; Takagi, K; Wang, L; Yokogawa, K1
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA1
Casciano, CN; Clement, RP; Johnson, WW; Wang, EJ1
Li, Y; Li, YH; Wang, YH; Yang, L; Yang, SL1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, X; Lin, X; Skolnik, S; Wang, J1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Blanco, MJ; Edmondson, Q; Furukawa, A; Handford, MJ; Hewitt, WM; Kelly, CN; Klein, VG; Lokey, RS; Ly, AM; Naylor, MR; Noland, RP; Pye, CR; Ramos, DP; Schwochert, J; Townsend, CE; Turmon, AC1
Iwamoto, K; Morikawa, K; Morikawa, S; Oseko, F1
Ferrari, SL; Goffin, E; Mourad, M; Pirson, Y; Squifflet, JP; Wallemacq, P1
Abramowicz, D; Demol, H; Quoidbach, A; Treille, S; Vereerstraeten, P1
Iwakawa, S; Komada, F; Ohba, M; Ohnishi, N; Okumura, K1
Barclay, P; Chapman, JR; Liddle, C; Nankivell, BJ; O'Connell, PJ; Spicer, ST; Thomas, P1
Garces, MC; McAllister, CK; Plemmons, RM; Ward, RL1
Alvarez-Grande, J; Gómez, E; Portal, C; Sánchez, JE; Sánchez-Nuñez, ML1
Azanza, JR; Cienfuegos, JA; López de Ocáriz, A; Quiroga, J; Sádaba, B1
Kantrow, SP; Knower, MT; Labella-Walker, K; McFadden, PM; Valentine, VG1
Ashihara, E; Fujita, N; Hatsuse, M; Inaba, T; Nakagawa, M; Noda, Y; Ochiai, N; Okano, A; Shimazaki, C; Takahashi, R1
Bartoli, F; Castronovo, G; De Iudicibus, S; Decorti, G; Di Lenarda, R; Gigante, A; Stocco, G1
Kamishina, H; Katayama, M; Katayama, R; Nishijima, N; Okamura, Y; Uzuka, Y; Yamashita, T1
Katayama, M; Katayama, R; Kawakami, Y; Okamura, Y; Shimamura, S; Uzuka, Y1
Gota, V; Mehta, M; Patel, K; Patil, A; Vavia, P1
Das, T; Foroutan, P; Gatenby, RA; Gillies, RJ; Kam, Y; Martinez, G; Minton, S; Ruiz, E; Tian, H1
Kishimoto, K; Matsuse, H; Nakayama, H; Oshio, T1
Damanhuri, NS; Kumolosasi, E; Mansor, AH; Omar, MS; Razak, AFA1

Reviews

2 review(s) available for clarithromycin and cyclosporine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Subcutaneous infection with Mycobacterium fortuitum after allogeneic bone marrow transplantation.
    Bone marrow transplantation, 2001, Volume: 28, Issue:7

    Topics: Adult; Bone Marrow Transplantation; Clarithromycin; Combined Modality Therapy; Cyclosporine; Debridement; Drug Therapy, Combination; Female; Graft vs Host Disease; Humans; Immunocompromised Host; Immunosuppressive Agents; Methotrexate; Minocycline; Mycobacterium fortuitum; Mycobacterium Infections, Nontuberculous; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Skin Ulcer; Tacrolimus; Transplantation Conditioning; Transplantation, Homologous

2001

Trials

1 trial(s) available for clarithromycin and cyclosporine

ArticleYear
The mechanism of cyclosporine toxicity induced by clarithromycin.
    British journal of clinical pharmacology, 1997, Volume: 43, Issue:2

    Topics: Anti-Bacterial Agents; Aryl Hydrocarbon Hydroxylases; Breath Tests; Carbon Radioisotopes; Clarithromycin; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Oxidoreductases, N-Demethylating; Reference Values

1997

Other Studies

29 other study(ies) available for clarithromycin and cyclosporine

ArticleYear
Reversal of anticancer drug resistance by macrolide antibiotics in vitro and in vivo.
    Clinical and experimental pharmacology & physiology, 2000, Volume: 27, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Cell Membrane; Cell Survival; Cyclosporine; Drug Resistance, Neoplasm; Immunosuppressive Agents; Leukemia P388; Macrolides; Mice; Neoplasm Transplantation; Tumor Cells, Cultured; Verapamil; Vinblastine

2000
Rational use of in vitro P-glycoprotein assays in drug discovery.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera

2001
Active transport of fluorescent P-glycoprotein substrates: evaluation as markers and interaction with inhibitors.
    Biochemical and biophysical research communications, 2001, Nov-30, Volume: 289, Issue:2

    Topics: 3T3 Cells; Adrenergic Uptake Inhibitors; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Biological Transport, Active; Cell Line; Cell Separation; Cell Survival; Flow Cytometry; Fluorescent Dyes; Humans; Inhibitory Concentration 50; Mice; Protein Binding; Reserpine; Spectrometry, Fluorescence; Substrate Specificity; Time Factors

2001
Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism.
    Bioorganic & medicinal chemistry letters, 2005, Sep-15, Volume: 15, Issue:18

    Topics: Computational Biology; Cyclohexanols; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Molecular Structure; Principal Component Analysis; Pyrrolizidine Alkaloids; Quantitative Structure-Activity Relationship; Reproducibility of Results; Substrate Specificity; Venlafaxine Hydrochloride

2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Lipophilic Permeability Efficiency Reconciles the Opposing Roles of Lipophilicity in Membrane Permeability and Aqueous Solubility.
    Journal of medicinal chemistry, 2018, 12-27, Volume: 61, Issue:24

    Topics: 1-Octanol; Cell Membrane Permeability; Cyclosporins; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Peptides; Peptides, Cyclic; Pharmaceutical Preparations; Small Molecule Libraries; Solubility; Structure-Activity Relationship; Water

2018
Immunomodulatory effects of three macrolides, midecamycin acetate, josamycin, and clarithromycin, on human T-lymphocyte function in vitro.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:11

    Topics: Adjuvants, Immunologic; Anti-Bacterial Agents; Cell Division; Cell Survival; Clarithromycin; Cyclosporine; Humans; Interleukin-2; Josamycin; Kinetics; Leucomycins; Leukocytes, Mononuclear; Receptors, Interleukin-2; Stimulation, Chemical; T-Lymphocytes; Tacrolimus

1994
The interaction between clarithromycin and cyclosporine in kidney transplant recipients.
    Transplantation, 1994, Sep-27, Volume: 58, Issue:6

    Topics: Adult; Clarithromycin; Creatinine; Cyclosporine; Drug Interactions; Graft Rejection; Humans; Kidney Transplantation; Male; Middle Aged

1994
Kidney graft dysfunction after drug interaction between clarithromycin and cyclosporin.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1996, Volume: 11, Issue:6

    Topics: Adult; Clarithromycin; Cyclosporine; Drug Interactions; Female; Humans; Kidney; Kidney Transplantation

1996
Effect of clarithromycin on the bioavailability of cyclosporin in rats.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:5

    Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Biological Availability; Clarithromycin; Cyclosporine; Cyclosporins; Drug Interactions; Erythromycin; Gastric Emptying; Infusions, Intravenous; Male; Rats; Rats, Wistar

1996
Osteomyelitis due to Mycobacterium haemophilum in a cardiac transplant patient: case report and analysis of interactions among clarithromycin, rifampin, and cyclosporine.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1997, Volume: 24, Issue:5

    Topics: Adult; Clarithromycin; Cyclosporine; Drug Interactions; Drug Therapy, Combination; Heart Transplantation; Humans; Immunosuppressive Agents; Male; Mycobacterium haemophilum; Mycobacterium Infections; Osteomyelitis; Rifampin

1997
Clarithromycin in the treatment of cyclosporin-associated gingival hyperplasia.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1997, Volume: 12, Issue:9

    Topics: Adult; Aged; Anti-Bacterial Agents; Clarithromycin; Cyclosporine; Female; Gingival Hyperplasia; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged

1997
Concurrent clarithromycin and cyclosporin A treatment.
    The Journal of antimicrobial chemotherapy, 1998, Volume: 42, Issue:3

    Topics: Anti-Bacterial Agents; Clarithromycin; Cyclosporine; Drug Interactions; Heart Transplantation; Humans; Immunosuppressive Agents; Liver Transplantation

1998
Clarithromycin for safe and cost-effective reduction of cyclosporine doses in lung allograft recipients.
    Southern medical journal, 2000, Volume: 93, Issue:11

    Topics: Adult; Anti-Bacterial Agents; Clarithromycin; Cost-Benefit Analysis; Cyclosporine; Female; Follow-Up Studies; Graft Rejection; Humans; Hypertension; Immunosuppressive Agents; Kidney; Lung Transplantation; Male; Matched-Pair Analysis; Postoperative Complications; Pseudomonas Infections; Transplantation, Homologous

2000
Role of MDR1 gene polymorphisms in gingival overgrowth induced by cyclosporine in transplant patients.
    Journal of periodontal research, 2008, Volume: 43, Issue:6

    Topics: Amoxicillin; Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Case-Control Studies; Clarithromycin; Cyclosporine; Dental Scaling; Female; Gingival Overgrowth; Heart Transplantation; Humans; Immunosuppressive Agents; Kidney Transplantation; Liver Transplantation; Logistic Models; Male; Middle Aged; Mutation, Missense; Oral Hygiene; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Prospective Studies

2008
Interaction of clarithromycin with cyclosporine in cats: pharmacokinetic study and case report.
    Journal of feline medicine and surgery, 2012, Volume: 14, Issue:4

    Topics: Animals; Cat Diseases; Cats; Clarithromycin; Cross-Over Studies; Cyclosporine; Dose-Response Relationship, Drug; Drug Interactions; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Transplantation; Male

2012
Preliminary study of effects of multiple oral dosing of clarithromycin on the pharmacokinetics of cyclosporine in dogs.
    The Journal of veterinary medical science, 2014, Volume: 76, Issue:3

    Topics: Administration, Oral; Animals; Biological Availability; Clarithromycin; Cyclosporine; Dogs; Dose-Response Relationship, Drug; Immunosuppression Therapy

2014
Oral delivery of paclitaxel nanocrystal (PNC) with a dual Pgp-CYP3A4 inhibitor: preparation, characterization and antitumor activity.
    International journal of pharmaceutics, 2014, Sep-10, Volume: 472, Issue:1-2

    Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Arginine; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chickens; Clarithromycin; Cyclosporine; Cytochrome P-450 CYP3A Inhibitors; Drug Compounding; Gastrointestinal Tract; Hypromellose Derivatives; Ileum; Melanoma, Experimental; Mice; Nanoparticles; Paclitaxel; Particle Size; Rats, Sprague-Dawley; Skin Neoplasms; Surface Properties; Tumor Burden

2014
Sweat but no gain: inhibiting proliferation of multidrug resistant cancer cells with "ersatzdroges".
    International journal of cancer, 2015, Feb-15, Volume: 136, Issue:4

    Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Cell Proliferation; Cell Survival; Clarithromycin; Cyclosporine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Erythromycin; Female; Gene Expression; Humans; Mammary Neoplasms, Experimental; MCF-7 Cells; Mice, Nude; Molecular Targeted Therapy; Tumor Burden; Verapamil; Xenograft Model Antitumor Assays

2015
[A CASE OF PULMONARY MYCOBACTERIUM ABSCESSUS INFECTION THAT DEVELOPED DURING IMMUNOSUPPRESSIVE THERAPY FOR MYASTHENIA GRAVIS WITH RECURRENT THYMOMA].
    Kekkaku : [Tuberculosis], 2016, Volume: 91, Issue:2

    Topics: Anti-Bacterial Agents; beta-Lactams; Clarithromycin; Cyclosporine; Drug Therapy, Combination; Glucocorticoids; Humans; Immunocompromised Host; Immunosuppressive Agents; Levofloxacin; Male; Middle Aged; Myasthenia Gravis; Mycobacterium Infections, Nontuberculous; Neoplasm Recurrence, Local; Thymoma; Thymus Neoplasms; Treatment Outcome

2016
The influence of P-glycoprotein expression in the standard treatment of Helicobacter pylori infection in Sprague Dawley rats.
    Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 2021, Volume: 29, Issue:1

    Topics: Amoxicillin; Animals; Anti-Bacterial Agents; Anti-Ulcer Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Clarithromycin; Cyclosporine; Drug Therapy, Combination; Helicobacter Infections; Helicobacter pylori; Male; Omeprazole; Proton Pump Inhibitors; Rats, Sprague-Dawley; Rifampin; Stomach Ulcer

2021