Page last updated: 2024-08-25

clarithromycin and 3'-hydroxy-5'-(4-isobutylpiperazinyl)benzoxazinorifamycin

clarithromycin has been researched along with 3'-hydroxy-5'-(4-isobutylpiperazinyl)benzoxazinorifamycin in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's14 (82.35)18.2507
2000's2 (11.76)29.6817
2010's0 (0.00)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Chen, J; Ding, C; Doyle, T; Duncan, L; Ebright, RH; He, S; Lin, W; Liu, Y; Lynch, AS; Ma, Z; Molodtsov, V; Nguyen, P; Pulse, M; Robertson, GT; Wang, H; Weiss, WJ; Xu, X; Yuan, Y; Zhuang, Z1
Dekio, S; Hidaka, T; Kawahara, S; Saito, H; Sato, K; Tomioka, H1
Barbara-Burnham, L; Bermudez, LE; Inderlied, CB; Wu, M; Young, LS1
Bermudez, LE; Inderlied, CB; Kolonoski, P; Young, LS1
Gidoh, M; Saito, H1
Amitani, R; Kuze, F; Murayama, T; Suzuki, K; Tanaka, E; Yamamoto, T1
Grosset, J; Ji, B; Lounis, N; Truffot-Pernot, C1
Akaki, T; Sato, K; Tomioka, H2
Akaki, T; Kawahara, S; Sato, K; Shimizu, T; Tomioka, H1
Amitani, R; Hashimoto, T; Kuze, F; Matsumoto, H; Suzuki, K; Tanaka, E; Tsuyuguchi, K; Yamamoto, T1
Sato, K; Tomioka, H2
Akaki, T; Ogasawara, K; Sato, K; Tomioka, H1
Gidoh, M; Hidaka, T; Kobayashi, K; Kwon, HH; Murakami, K; Saito, H1
Akaki, T; Kawahara, S; Sato, K; Tomioka, H1
Sano, C; Sano, K; Sato, K; Shimizu, T; Tomioka, H1

Reviews

2 review(s) available for clarithromycin and 3'-hydroxy-5'-(4-isobutylpiperazinyl)benzoxazinorifamycin

ArticleYear
[Present status of studies on antileprosy drugs].
    Nihon Rai Gakkai zasshi, 1995, Volume: 64, Issue:3

    Topics: Animals; Clarithromycin; Dapsone; Drug Therapy, Combination; Humans; Immunologic Factors; Leprostatic Agents; Minocycline; Prothionamide; Quinolones; Rifampin; Rifamycins; Thalidomide

1995
[In vitro antimicrobial activities of quinolones, rifamycins and macrolides against Mycobacterium tuberculosis and M.avium complex: attempt to establish new assay methods which accurately reflect therapeutic effects of test agents in vivo].
    Kekkaku : [Tuberculosis], 1999, Volume: 74, Issue:1

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Cells, Cultured; Clarithromycin; Drug Resistance, Microbial; Humans; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium tuberculosis; Ofloxacin; Rifamycins

1999

Trials

1 trial(s) available for clarithromycin and 3'-hydroxy-5'-(4-isobutylpiperazinyl)benzoxazinorifamycin

ArticleYear
Activity of KRM 1648 or rifabutin alone or in combination with clarithromycin against Mycobacterium avium complex in human alveolar macrophages.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 1997, Volume: 1, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Antibiotics, Antitubercular; Bronchoalveolar Lavage; Cells, Cultured; Clarithromycin; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; L-Lactate Dehydrogenase; Macrophages, Alveolar; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium avium Complex; Reference Values; Rifabutin; Rifamycins; Smoking

1997

Other Studies

14 other study(ies) available for clarithromycin and 3'-hydroxy-5'-(4-isobutylpiperazinyl)benzoxazinorifamycin

ArticleYear
Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens.
    Journal of medicinal chemistry, 2022, 03-24, Volume: 65, Issue:6

    Topics: Anaerobiosis; DNA-Directed RNA Polymerases; Helicobacter Infections; Helicobacter pylori; Humans; Nitroimidazoles; Rifamycins

2022
Therapeutic effect of KRM-1648 with various antimicrobials against Mycobacterium avium complex infection in mice.
    Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 1995, Volume: 76, Issue:1

    Topics: Animals; Antitubercular Agents; Clarithromycin; Clofazimine; Drug Synergism; Drug Therapy, Combination; Ethambutol; Fluoroquinolones; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microbial Sensitivity Tests; Mycobacterium avium-intracellulare Infection; Ofloxacin; Quinolones; Rifamycins; Streptomycin

1995
Activities of the benzoxazinorifamycin KRM 1648 and ethambutol against Mycobacterium avium complex in vitro and in macrophages.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:8

    Topics: Antibiotics, Antitubercular; Cell Line; Clarithromycin; Ethambutol; Humans; Macrophages; Microbial Sensitivity Tests; Mycobacterium avium Complex; Rifamycins

1994
Activity of KRM 1648 alone or in combination with ethambutol or clarithromycin against Mycobacterium avium in beige mouse model of disseminated infection.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:8

    Topics: Animals; Antibiotics, Antitubercular; Clarithromycin; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ethambutol; Female; Mice; Mice, Inbred C57BL; Mycobacterium avium; Rifamycins; Tuberculosis

1994
Activity of KRM-1648 alone or in combination with both ethambutol and kanamycin or clarithromycin against Mycobacterium intracellulare infections in beige mice.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antitubercular; Antitubercular Agents; Clarithromycin; Colony Count, Microbial; Drug Combinations; Drug Therapy, Combination; Ethambutol; Female; Kanamycin; Lung; Male; Mice; Mycobacterium avium Complex; Rifampin; Rifamycins; Spleen; Tuberculosis

1996
How effective is KRM-1648 in treatment of disseminated Mycobacterium avium complex infections in beige mice?
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antitubercular; Clarithromycin; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Kanamycin; Lung; Male; Mice; Microbial Sensitivity Tests; Mycobacterium avium Complex; Rifamycins; Spleen; Tuberculosis

1996
[Anti-Mycobacterium avium complex activities of KRM-1648, clarithromycin and levofloxacin in 7HSF medium at peak or average blood concentrations after their oral administration of clinical dosages].
    Kekkaku : [Tuberculosis], 1997, Volume: 72, Issue:7

    Topics: Administration, Oral; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Clarithromycin; Culture Media; Humans; Levofloxacin; Mycobacterium avium Complex; Ofloxacin; Rifamycins

1997
[In vivo activities of benzoxazinorifamycin KRM-1648, clarithromycin, and levofloxacin, or combination of KRM-1648 with diclofenac sodium against Mycobacterium avium infection induced in mice].
    Kekkaku : [Tuberculosis], 1997, Volume: 72, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antitubercular; Clarithromycin; Diclofenac; Drug Therapy, Combination; Female; Levofloxacin; Mice; Mice, Inbred BALB C; Mycobacterium avium; Ofloxacin; Rifamycins; Tuberculosis

1997
Antimicrobial activities of benzoxazinorifamycin KRM-1648, clarithromycin and levofloxacin against intracellular Mycobacterium avium complex phagocytosed by murine peritoneal macrophages.
    The Journal of antimicrobial chemotherapy, 1998, Volume: 41, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Clarithromycin; Female; Levofloxacin; Lung; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium avium; Ofloxacin; Phagocytosis; Rifamycins; Tuberculosis

1998
Antimicrobial activities of benzoxazinorifamycin (KRM-1648) and clarithromycin against Mycobacterium avium-intracellulare complex within murine peritoneal macrophages, human macrophage-like cells and human alveolar epithelial cells.
    The Journal of antimicrobial chemotherapy, 1999, Volume: 43, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Cell Line; Clarithromycin; Epithelial Cells; Female; Humans; Macrophages; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium avium Complex; Pulmonary Alveoli; Rifamycins

1999
[MICs and MBCs of levofloxacin, clarithromycin, and KRM-1648 for Mycobacterium tuberculosis and M. avium complex residing in MONO-MAC-6 human macrophage-like cell and A-549 human type II alveolar epithelial cell lines].
    Kekkaku : [Tuberculosis], 1999, Volume: 74, Issue:7

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Cells, Cultured; Clarithromycin; Humans; Levofloxacin; Macrophages; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium tuberculosis; Ofloxacin; Pulmonary Alveoli; Rifamycins

1999
[Chemoprophylaxis against Mycobacterium avium complex infection induced in mice].
    Kekkaku : [Tuberculosis], 1999, Volume: 74, Issue:9

    Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antitubercular; Clarithromycin; Female; Mice; Mycobacterium avium-intracellulare Infection; Rifabutin; Rifamycins

1999
Antimicrobial activities of levofloxacin, clarithromycin, and KRM-1648 against Mycobacterium tuberculosis and Mycobacterium avium complex replicating within Mono Mac 6 human macrophage and A-549 type II alveolar cell lines.
    International journal of antimicrobial agents, 2000, Volume: 16, Issue:1

    Topics: Anti-Bacterial Agents; Cell Line; Clarithromycin; Epithelial Cells; Humans; Levofloxacin; Macrophages; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Mycobacterium tuberculosis; Ofloxacin; Pulmonary Alveoli; Rifamycins; Tuberculosis

2000
Intramacrophage passage of Mycobacterium tuberculosis and M. avium complex alters the drug susceptibilities of the organisms as determined by intracellular susceptibility testing using macrophages and type II alveolar epithelial cells.
    Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:2

    Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Cells, Cultured; Clarithromycin; Epithelial Cells; Humans; Levofloxacin; Macrophages; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium tuberculosis; Ofloxacin; Rifamycins

2002