cl 218872 has been researched along with zolpidem in 25 studies
| Studies (cl 218872) | Trials (cl 218872) | Recent Studies (post-2010) (cl 218872) | Studies (zolpidem) | Trials (zolpidem) | Recent Studies (post-2010) (zolpidem) |
|---|---|---|---|---|---|
| 158 | 0 | 3 | 1,825 | 368 | 683 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (12.00) | 18.7374 |
| 1990's | 14 (56.00) | 18.2507 |
| 2000's | 7 (28.00) | 29.6817 |
| 2010's | 1 (4.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lüddens, H; Wieland, HA | 1 |
| Cook, JM; Cox, ED; Diaz-Arauzo, H; Harris, B; Huang, Q; Ma, C; McKernan, R; Reddy, MS; Skolnick, P | 1 |
| Cook, JM; Dayer, CA; He, X; Huang, Q; Liu, R; Ma, C; McKernan, R; Wenger, GR; Yu, S | 1 |
| Atack, JR; Carling, RW; Castro, JL; Cook, SM; Dawson, GR; Ferris, P; Isted, C; Leeson, PD; McKernan, RM; Moore, KW; O'Connor, D; Quirk, K; Street, LJ; Thomas, S; Thompson, SA; Wafford, KA; Wild, D | 1 |
| Atack, JR; Bromidge, FA; Carling, RW; Castro, JL; Cook, SM; Hunt, P; Isted, C; Lucas, M; Macaulay, AJ; McKernan, RM; Mitchinson, A; Moore, KW; Narquizian, R; Russell, MG; Thomas, D; Thompson, SA; Wafford, KA | 1 |
| Clayton, T; Cook, JM; Cromer, BA; Ma, C; Majumder, S; Namjoshi, OA; Petrou, S; Platt, DM; Roth, BL; VanLinn, ML; Yin, W | 1 |
| Arbilla, S; Benavides, J; Durand, A; Peny, B; Scatton, B | 1 |
| Bacon, E; de Barry, J; Gombos, G | 1 |
| De Luca, C; De Medici, D; Massotti, M | 1 |
| Benavides, J; Dubois, A; Morel, E; Peny, B; Perrault, G; Scatton, B; Zivkovic, B | 1 |
| Arbilla, S; Langer, SZ | 1 |
| Joly, D; Sanger, DJ; Zivkovic, B | 1 |
| Cancedda, E; Corda, MG; Giorgi, O; Lecca, D; Serra, GP | 1 |
| Bannwarth, W; Benke, D; Fritschy, JM; Mohler, H; Trzeciak, A | 1 |
| Erickson, A; Hendrickson, A; March, D; Richards, G; Shaw, C | 1 |
| Benavides, J; Peny, B; Ruano, D; Scatton, B; Vitorica, J | 1 |
| Machado, A; Ruano, D; Vitorica, J | 1 |
| Hadingham, KL; Palmer, KJ; Thompson, SA; Wafford, KA; Whiting, PJ | 1 |
| Araujo, F; Benavides, J; Ruano, D; Schoemaker, H; Tan, S; Vitorica, J | 1 |
| Atack, JR; Emms, F; McKernan, RM; Smith, AJ | 1 |
| Araujo, F; Ruano, D; Vitorica, J | 1 |
| Bromidge, FA; Casula, MA; Hadingham, KL; Martin, K; Maubach, K; Pillai, GV; Seabrook, GR; Whiting, PJ; Wingrove, PB | 1 |
| Safo, P; Thompson, SA; Wafford, KA; Wheat, L; Whiting, PJ; Wingrove, PB | 1 |
| Cook, JM; Lelas, S; Rowlett, JK; Spealman, RD; Yin, W | 1 |
| Mathiasen, LS; Mirza, NR; Rodgers, RJ | 1 |
25 other study(ies) available for cl 218872 and zolpidem
| Article | Year |
|---|---|
Four amino acid exchanges convert a diazepam-insensitive, inverse agonist-preferring GABAA receptor into a diazepam-preferring GABAA receptor.
Topics: Amino Acid Sequence; Azides; Base Sequence; Benzodiazepines; Binding Sites; Diazepam; GABA Agonists; Humans; Molecular Sequence Data; Mutation; Receptors, GABA-A; Structure-Activity Relationship | 1994 |
Synthesis and evaluation of analogues of the partial agonist 6-(propyloxy)-4-(methoxymethyl)-beta-carboline-3-carboxylic acid ethyl ester (6-PBC) and the full agonist 6-(benzyloxy)-4-(methoxymethyl)-beta-carboline-3-carboxylic acid ethyl ester (Zk 93423)
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Binding, Competitive; Carbolines; Cell Line; Cerebral Cortex; Drug Design; GABA Agonists; Humans; Male; Mice; Muscle Relaxation; Rats; Receptors, GABA-A; Recombinant Proteins; Seizures; Structure-Activity Relationship | 1998 |
Pharmacophore/receptor models for GABA(A)/BzR subtypes (alpha1beta3gamma2, alpha5beta3gamma2, and alpha6beta3gamma2) via a comprehensive ligand-mapping approach.
Topics: Animals; Benzodiazepines; Carbolines; Cell Line; Columbidae; Conditioning, Operant; Crystallography, X-Ray; Humans; Indoles; Ligands; Male; Models, Molecular; Pyrimidines; Quinolones; Radioligand Assay; Receptors, GABA-A; Saimiri; Stereoisomerism; Structure-Activity Relationship | 2000 |
3-phenyl-6-(2-pyridyl)methyloxy-1,2,4-triazolo[3,4-a]phthalazines and analogues: high-affinity gamma-aminobutyric acid-A benzodiazepine receptor ligands with alpha 2, alpha 3, and alpha 5-subtype binding selectivity over alpha 1.
Topics: Animals; Anti-Anxiety Agents; Binding, Competitive; Biological Availability; Cell Line; GABA-A Receptor Agonists; Humans; Magnetic Resonance Spectroscopy; Maze Learning; Oocytes; Patch-Clamp Techniques; Phthalazines; Radioligand Assay; Rats; Receptors, GABA-A; Recombinant Proteins; Structure-Activity Relationship; Triazoles; Xenopus | 2004 |
Discovery of functionally selective 7,8,9,10-tetrahydro-7,10-ethano-1,2,4-triazolo[3,4-a]phthalazines as GABA A receptor agonists at the alpha3 subunit.
Topics: Animals; Binding Sites; Cell Line; Female; GABA-A Receptor Agonists; Humans; Models, Molecular; Oocytes; Patch-Clamp Techniques; Phthalazines; Protein Subunits; Radioligand Assay; Receptors, GABA-A; Structure-Activity Relationship; Triazoles; Xenopus laevis | 2005 |
Design, synthesis, and subtype selectivity of 3,6-disubstituted β-carbolines at Bz/GABA(A)ergic receptors. SAR and studies directed toward agents for treatment of alcohol abuse.
Topics: Alcoholism; Animals; Benzodiazepines; Binding Sites; Carbolines; Cell Line; Computer Simulation; GABA-A Receptor Antagonists; Humans; Protein Subunits; Rats; Receptors, GABA-A; Stereoisomerism; Structure-Activity Relationship | 2010 |
Comparative in vivo and in vitro regional selectivity of central omega (benzodiazepine) site ligands in inhibiting [3H]flumazenil binding in the rat central nervous system.
Topics: Animals; Benzodiazepines; Binding Sites; Binding, Competitive; Brain Chemistry; Cell Membrane; Central Nervous System; Flumazenil; Hypnotics and Sedatives; Pyridazines; Pyridines; Rats; Receptors, GABA-A; Triazolam; Zolpidem | 1992 |
Differential ontogenesis of type I and II benzodiazepine receptors in mouse cerebellum.
Topics: Aging; Animals; Cerebellum; Flunitrazepam; Mice; Models, Biological; Pyridazines; Pyridines; Receptors, GABA-A; Zolpidem | 1991 |
Relative efficacies of benzodiazepine receptor agonists in affecting red nucleus electrical activity in rabbits.
Topics: Animals; Bicuculline; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Flunitrazepam; Imidazoles; Isoquinolines; Male; Pentylenetetrazole; Pyridazines; Pyridines; Rabbits; Receptors, GABA-A; Red Nucleus; Zolpidem | 1990 |
In vivo interaction of zolpidem with central benzodiazepine (BZD) binding sites (as labeled by [3H]Ro 15-1788) in the mouse brain. Preferential affinity of zolpidem for the omega 1 (BZD1) subtype.
Topics: Animals; Autoradiography; Binding Sites; Brain; Flumazenil; Flunitrazepam; Hypnotics and Sedatives; In Vitro Techniques; Male; Mice; Pyridazines; Pyridines; Receptors, GABA-A; Zolpidem | 1988 |
Imidazopyridines as a tool for the characterization of benzodiazepine receptors: a proposal for a pharmacological classification as omega receptor subtypes.
Topics: Animals; Brain Chemistry; Flunitrazepam; GABA-A Receptor Antagonists; Imidazoles; In Vitro Techniques; Isoquinolines; Kidney; Ligands; Pyridazines; Pyridines; Rats; Receptors, GABA-A; Spinal Cord; Terminology as Topic; Zolpidem | 1988 |
Effects of zolpidem, a new imidazopyridine hypnotic, on the acquisition of conditioned fear in mice. Comparison with triazolam and CL 218,872.
Topics: Animals; Anti-Anxiety Agents; Conditioning, Operant; Fear; Hypnotics and Sedatives; Male; Mice; Motor Activity; Pyridazines; Pyridines; Triazolam; Zolpidem | 1986 |
Modulation of [35S]TBPS binding by ligands with preferential affinity for benzodiazepine BZ1 sites in the cerebral cortex of newborn and adult rats.
Topics: Age Factors; Animals; Animals, Newborn; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Female; Flunitrazepam; Male; Pregnancy; Pyridazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Zolpidem | 1995 |
Distribution, prevalence, and drug binding profile of gamma-aminobutyric acid type A receptor subtypes differing in the beta-subunit variant.
Topics: Animals; Brain Chemistry; Carbolines; Flumazenil; Flunitrazepam; Genetic Variation; Immunohistochemistry; Male; Microscopy, Confocal; Molecular Weight; Precipitin Tests; Protein Conformation; Pyridazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Tissue Distribution; Zolpidem | 1994 |
Coincidental appearance of the alpha 1 subunit of the GABA-A receptor and the type I benzodiazepine receptor near birth in macaque monkey visual cortex.
Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Antibodies, Monoclonal; Autoradiography; Binding, Competitive; Female; Flunitrazepam; Hypnotics and Sedatives; Immunohistochemistry; Ligands; Macaca nemestrina; Pregnancy; Pyridazines; Pyridines; Receptors, GABA-A; Visual Cortex; Zolpidem | 1994 |
Comparative autoradiographic distribution of central omega (benzodiazepine) modulatory site subtypes with high, intermediate and low affinity for zolpidem and alpidem.
Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Autoradiography; Binding, Competitive; Brain; Flumazenil; Hypnotics and Sedatives; Imidazoles; Kinetics; Male; Organ Specificity; Pyridazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Spinal Cord; Tritium; Zolpidem | 1993 |
Absence of modifications of the pharmacological properties of the GABAA receptor complex during aging, as assessed in 3- and 24-month-old rat cerebral cortex.
Topics: Affinity Labels; Aging; Animals; Anti-Anxiety Agents; Binding, Competitive; Cerebral Cortex; Flunitrazepam; Hypnotics and Sedatives; In Vitro Techniques; Male; Membrane Proteins; Muscimol; Photochemistry; Pyridazines; Pyridines; Rats; Rats, Inbred F344; Rats, Wistar; Receptors, GABA-A; Zolpidem | 1993 |
Expression and pharmacology of human GABAA receptors containing gamma 3 subunits.
Topics: Amino Acid Sequence; Animals; Anti-Anxiety Agents; Base Sequence; Benzodiazepines; Benzodiazepinones; Carbolines; Flumazenil; Flunitrazepam; GABA Modulators; Humans; Molecular Sequence Data; Pyrazoles; Pyridazines; Pyridines; Receptors, GABA-A; Recombinant Proteins; Sequence Homology, Amino Acid; Triazolam; Xenopus; Zolpidem | 1995 |
Molecular and pharmacological characterization of native cortical gamma-aminobutyric acidA receptors containing both alpha1 and alpha3 subunits.
Topics: Amino Acid Sequence; Animals; Anti-Anxiety Agents; Antibodies; Binding Sites; Cattle; Cell Membrane; Cerebral Cortex; Chromatography, Affinity; Flumazenil; Hypnotics and Sedatives; Immunoblotting; Kinetics; Macromolecular Substances; Models, Structural; Peptide Fragments; Pyridazines; Pyridines; Rats; Rats, Wistar; Receptors, GABA-A; Zolpidem | 1996 |
Regional differences in the inhibition of mouse in vivo [3H]Ro 15-1788 binding reflect selectivity for alpha 1 versus alpha 2 and alpha 3 subunit-containing GABAA receptors.
Topics: Animals; Benzodiazepines; Binding Sites; Cerebellum; Flumazenil; GABA Modulators; GABA-A Receptor Antagonists; In Vitro Techniques; Ligands; Male; Mice; Pyridazines; Pyridines; Receptors, GABA-A; Spinal Cord; Time Factors; Tritium; Zolpidem | 1999 |
Native gamma-aminobutyric acid type A receptors from rat hippocampus, containing both alpha 1 and alpha 5 subunits, exhibit a single benzodiazepine binding site with alpha 5 pharmacological properties.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Binding Sites; Chromatography, Affinity; Flumazenil; GABA Modulators; Hippocampus; Hypnotics and Sedatives; Macromolecular Substances; Precipitin Tests; Pyridazines; Pyridines; Rats; Rats, Wistar; Receptors, GABA-A; Tritium; Zolpidem | 1999 |
Identification of amino acid residues responsible for the alpha5 subunit binding selectivity of L-655,708, a benzodiazepine binding site ligand at the GABA(A) receptor.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Anti-Anxiety Agents; Azides; Benzodiazepines; Binding Sites; Binding, Competitive; Carbolines; DNA, Complementary; Female; Flumazenil; Flunitrazepam; GABA-A Receptor Agonists; Humans; Imidazoles; Isoleucine; Ligands; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Protein Binding; Protein Structure, Tertiary; Protein Subunits; Pyridazines; Pyridines; Receptors, GABA-A; Recombinant Fusion Proteins; Sequence Alignment; Structure-Activity Relationship; Threonine; Transfection; Xenopus laevis; Zolpidem | 2001 |
Mechanism of alpha-subunit selectivity of benzodiazepine pharmacology at gamma-aminobutyric acid type A receptors.
Topics: Animals; Anti-Anxiety Agents; Binding, Competitive; Cell Line; Diazepam; Dose-Response Relationship, Drug; Female; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Humans; Membrane Potentials; Mutation; Oocytes; Protein Subunits; Pyridazines; Pyridines; Radioligand Assay; Receptors, GABA-A; Tritium; Xenopus laevis; Zolpidem | 2002 |
Discriminative stimulus effects of zolpidem in squirrel monkeys: role of GABA(A)/alpha1 receptors.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Benzodiazepines; Carbolines; Discrimination Learning; Dose-Response Relationship, Drug; Flunitrazepam; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; Injections, Intravenous; Male; Pyridazines; Pyridines; Receptors, GABA-A; Saimiri; Zolpidem | 2003 |
Comparative cue generalization profiles of L-838, 417, SL651498, zolpidem, CL218,872, ocinaplon, bretazenil, zopiclone, and various benzodiazepines in chlordiazepoxide and zolpidem drug discrimination.
Topics: Animals; Azabicyclo Compounds; Benzodiazepines; Benzodiazepinones; Chlordiazepoxide; Cues; Discrimination Learning; Fluorobenzenes; GABA Modulators; Generalization, Psychological; Male; Piperazines; Protein Subunits; Pyridazines; Pyridines; Rats; Receptors, GABA-A; Triazoles; Zolpidem | 2006 |